' 
![]()
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.2
USERS' SCORE
Good
Based on 1 Reviews
8.2
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Turmeric ExtractCurcuma longa (Rhizome)(95% [475 mg] Total Curcuminoids)
500 mg
†
Top Medical Research Studies
9
Curcuma extract improves reflux symptoms
Protective Effects of Inflammation of Curcumae Longae Rhizoma 30% EtOH Extract on Acute Reflux Esophagitis Rats.
Supports turmeric's digestive benefits
We evaluated how Curcumae Longae Rhizoma extract, which contains the well-known compound curcumin, influences reflux conditions in rats suffering from acute reflux esophagitis (ARE). Through a series of experiments, we were able to measure various antioxidant and inflammatory markers, providing insight into how this natural treatment helps manage reflux symptoms.
To investigate the protective effects of this turmeric extract, we induced ARE in Sprague-Dawley rats and administered the extract prior to the onset of reflux. Remarkably, we found that the inclusion of the turmeric extract significantly reduced tissue damage in the esophagus of the treated rats. Moreover, the levels of harmful substances typically associated with inflammation and oxidative stress, such as alanine aminotransferase (ALT) and aspartate aminotransferase (AST), were notably decreased.
Additionally, our results indicated that the turmeric extract helped promote antioxidant activity while suppressing pro-inflammatory proteins. This suggests that Curcumae Longae Rhizoma may be a promising therapeutic option for managing reflux-related conditions effectively. Overall, we were encouraged by the findings that indicate its potential role in both prevention and treatment of acute reflux esophagitis.
To investigate the protective effects of this turmeric extract, we induced ARE in Sprague-Dawley rats and administered the extract prior to the onset of reflux. Remarkably, we found that the inclusion of the turmeric extract significantly reduced tissue damage in the esophagus of the treated rats. Moreover, the levels of harmful substances typically associated with inflammation and oxidative stress, such as alanine aminotransferase (ALT) and aspartate aminotransferase (AST), were notably decreased.
Additionally, our results indicated that the turmeric extract helped promote antioxidant activity while suppressing pro-inflammatory proteins. This suggests that Curcumae Longae Rhizoma may be a promising therapeutic option for managing reflux-related conditions effectively. Overall, we were encouraged by the findings that indicate its potential role in both prevention and treatment of acute reflux esophagitis.
Read More
7
Curcumin benefits gastrointestinal health
Curcumin: A Potent Protectant against Esophageal and Gastric Disorders.
Moderate relevance to reflux treatment
We examined the power of curcumin, the active ingredient in turmeric, in relation to reflux and other upper gastrointestinal issues. The research presented encouraged us by showing that curcumin has several valuable properties, including anti-inflammatory and antioxidant effects, which may help in protecting the gastrointestinal tract.
Curcumin has been noted for its potential to guard against conditions like reflux esophagitis and even damage caused by common medications such as nonsteroidal anti-inflammatory drugs (NSAIDs). By reducing inflammation and promoting healing, we see curcumin as a promising player in the fight against reflux.
While promising results regarding its role in managing reflux symptoms have been shared, further detailed studies involving direct comparisons with established treatments are essential to define its effectiveness more clearly. Hence, we advocate for more research to explore the full potential of curcumin in gastrointestinal health, particularly concerning reflux conditions.
Curcumin has been noted for its potential to guard against conditions like reflux esophagitis and even damage caused by common medications such as nonsteroidal anti-inflammatory drugs (NSAIDs). By reducing inflammation and promoting healing, we see curcumin as a promising player in the fight against reflux.
While promising results regarding its role in managing reflux symptoms have been shared, further detailed studies involving direct comparisons with established treatments are essential to define its effectiveness more clearly. Hence, we advocate for more research to explore the full potential of curcumin in gastrointestinal health, particularly concerning reflux conditions.
Read More
9
Curcumin enhances reflux treatment
Enhanced oral delivery and anti-gastroesophageal reflux activity of curcumin by binary mixed micelles.
Focused on curcumin's effectiveness
We aimed to discover how curcumin, a natural compound often touted for its health benefits, can help with gastroesophageal reflux. To enhance its effectiveness, we created two special formulations called binary mixed micelles, which help increase curcumin's solubility and absorption in the body.
These formulations, known as CM-T and CM-F, were prepared using different ingredients and methods. After testing, we found that both formulations significantly increased the oral bioavailability of curcumin—meaning that a greater amount reached the bloodstream compared to regular curcumin.
Interestingly, we observed improved efficacy against gastroesophageal reflux in both micelle formulations when compared to free curcumin. This suggests that our micelle approach may be a promising way to enhance the benefits of curcumin for those suffering from reflux conditions.
These formulations, known as CM-T and CM-F, were prepared using different ingredients and methods. After testing, we found that both formulations significantly increased the oral bioavailability of curcumin—meaning that a greater amount reached the bloodstream compared to regular curcumin.
Interestingly, we observed improved efficacy against gastroesophageal reflux in both micelle formulations when compared to free curcumin. This suggests that our micelle approach may be a promising way to enhance the benefits of curcumin for those suffering from reflux conditions.
Read More
Most Useful Reviews
4.8
Limited reflux relief
So far so good; it might be helping with general inflammation. However, it hasn't yet alleviated my reflux as I hoped. It can stain clothing yellow, yet it has had no negative effects.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.2
9
Curcuma extract improves reflux symptoms
Protective Effects of Inflammation of Curcumae Longae Rhizoma 30% EtOH Extract on Acute Reflux Esophagitis Rats.
Supports turmeric's digestive benefits
We evaluated how Curcumae Longae Rhizoma extract, which contains the well-known compound curcumin, influences reflux conditions in rats suffering from acute reflux esophagitis (ARE). Through a series of experiments, we were able to measure various antioxidant and inflammatory markers, providing insight into how this natural treatment helps manage reflux symptoms.
To investigate the protective effects of this turmeric extract, we induced ARE in Sprague-Dawley rats and administered the extract prior to the onset of reflux. Remarkably, we found that the inclusion of the turmeric extract significantly reduced tissue damage in the esophagus of the treated rats. Moreover, the levels of harmful substances typically associated with inflammation and oxidative stress, such as alanine aminotransferase (ALT) and aspartate aminotransferase (AST), were notably decreased.
Additionally, our results indicated that the turmeric extract helped promote antioxidant activity while suppressing pro-inflammatory proteins. This suggests that Curcumae Longae Rhizoma may be a promising therapeutic option for managing reflux-related conditions effectively. Overall, we were encouraged by the findings that indicate its potential role in both prevention and treatment of acute reflux esophagitis.
To investigate the protective effects of this turmeric extract, we induced ARE in Sprague-Dawley rats and administered the extract prior to the onset of reflux. Remarkably, we found that the inclusion of the turmeric extract significantly reduced tissue damage in the esophagus of the treated rats. Moreover, the levels of harmful substances typically associated with inflammation and oxidative stress, such as alanine aminotransferase (ALT) and aspartate aminotransferase (AST), were notably decreased.
Additionally, our results indicated that the turmeric extract helped promote antioxidant activity while suppressing pro-inflammatory proteins. This suggests that Curcumae Longae Rhizoma may be a promising therapeutic option for managing reflux-related conditions effectively. Overall, we were encouraged by the findings that indicate its potential role in both prevention and treatment of acute reflux esophagitis.
Read More
9
Curcumin may prevent bile reflux cancer
The in vivo preventive and therapeutic properties of curcumin in bile reflux-related oncogenesis of the hypopharynx.
Moderate relevance to reflux treatments
We explored how curcumin, a compound found in turmeric, can impact the harmful effects of bile reflux on the hypopharynx. This condition, which can result in cancer, is exacerbated by bile at a highly acidic pH. Our investigation specifically looked at whether curcumin could block the early signs of cancer caused by bile acids.
To examine this, we conducted experiments using mice, applying curcumin directly to the hypopharynx before and after exposing them to bile acids. We noted that curcumin significantly reduced the activation of a protein called NF-κB, which is involved in cancer development. Additionally, curcumin seemed to influence the expression of several genes linked to oncogenesis, highlighting its potential preventative benefits.
Overall, the findings provide exciting insights into curcumin’s ability to serve as a topical treatment against acid-induced cancer risk, potentially leading to new, non-drug therapies. We believe that with further research, curcumin could become an important player in managing bile reflux's oncogenic effects.
To examine this, we conducted experiments using mice, applying curcumin directly to the hypopharynx before and after exposing them to bile acids. We noted that curcumin significantly reduced the activation of a protein called NF-κB, which is involved in cancer development. Additionally, curcumin seemed to influence the expression of several genes linked to oncogenesis, highlighting its potential preventative benefits.
Overall, the findings provide exciting insights into curcumin’s ability to serve as a topical treatment against acid-induced cancer risk, potentially leading to new, non-drug therapies. We believe that with further research, curcumin could become an important player in managing bile reflux's oncogenic effects.
Read More
9
Curcumin enhances reflux treatment
Enhanced oral delivery and anti-gastroesophageal reflux activity of curcumin by binary mixed micelles.
Focused on curcumin's effectiveness
We aimed to discover how curcumin, a natural compound often touted for its health benefits, can help with gastroesophageal reflux. To enhance its effectiveness, we created two special formulations called binary mixed micelles, which help increase curcumin's solubility and absorption in the body.
These formulations, known as CM-T and CM-F, were prepared using different ingredients and methods. After testing, we found that both formulations significantly increased the oral bioavailability of curcumin—meaning that a greater amount reached the bloodstream compared to regular curcumin.
Interestingly, we observed improved efficacy against gastroesophageal reflux in both micelle formulations when compared to free curcumin. This suggests that our micelle approach may be a promising way to enhance the benefits of curcumin for those suffering from reflux conditions.
These formulations, known as CM-T and CM-F, were prepared using different ingredients and methods. After testing, we found that both formulations significantly increased the oral bioavailability of curcumin—meaning that a greater amount reached the bloodstream compared to regular curcumin.
Interestingly, we observed improved efficacy against gastroesophageal reflux in both micelle formulations when compared to free curcumin. This suggests that our micelle approach may be a promising way to enhance the benefits of curcumin for those suffering from reflux conditions.
Read More
7
Curcumin benefits gastrointestinal health
Curcumin: A Potent Protectant against Esophageal and Gastric Disorders.
Moderate relevance to reflux treatment
We examined the power of curcumin, the active ingredient in turmeric, in relation to reflux and other upper gastrointestinal issues. The research presented encouraged us by showing that curcumin has several valuable properties, including anti-inflammatory and antioxidant effects, which may help in protecting the gastrointestinal tract.
Curcumin has been noted for its potential to guard against conditions like reflux esophagitis and even damage caused by common medications such as nonsteroidal anti-inflammatory drugs (NSAIDs). By reducing inflammation and promoting healing, we see curcumin as a promising player in the fight against reflux.
While promising results regarding its role in managing reflux symptoms have been shared, further detailed studies involving direct comparisons with established treatments are essential to define its effectiveness more clearly. Hence, we advocate for more research to explore the full potential of curcumin in gastrointestinal health, particularly concerning reflux conditions.
Curcumin has been noted for its potential to guard against conditions like reflux esophagitis and even damage caused by common medications such as nonsteroidal anti-inflammatory drugs (NSAIDs). By reducing inflammation and promoting healing, we see curcumin as a promising player in the fight against reflux.
While promising results regarding its role in managing reflux symptoms have been shared, further detailed studies involving direct comparisons with established treatments are essential to define its effectiveness more clearly. Hence, we advocate for more research to explore the full potential of curcumin in gastrointestinal health, particularly concerning reflux conditions.
Read More
7
Curcumin shows promise for reflux
Effects of curcumin on reflux esophagitis in rats.
Combining treatments limits clarity
We explored the effects of curcumin, a compound found in turmeric, on reflux esophagitis using a rat model. This study aimed to assess whether curcumin could serve as a potential treatment for gastroesophageal reflux disease (GERD).
In our experiments, we administered curcumin alongside other treatments like dimethyl sulfoxide (DMSO) and lansoprazole to see how well it could prevent acute acid reflux esophagitis. While we found that curcumin did show some preventative effects—reducing esophagitis formation by about 52.5%—it was less effective than lansoprazole, which blocked reflux by nearly 71%.
Interestingly, when combined with DMSO, curcumin helped lower the severity of chronic esophagitis to levels similar to those seen with lansoprazole. Although curcumin alone couldn’t prevent chronic reflux esophagitis, its benefits were notable, especially in reducing neutrophil infiltration compared to the control group. However, lansoprazole seemed to worsen some histopathological changes.
Overall, while curcumin isn't as powerful as lansoprazole for acute reflux, it is particularly promising in cases of mixed reflux esophagitis and is thought to work due to its antioxidant and anti-inflammatory properties.
In our experiments, we administered curcumin alongside other treatments like dimethyl sulfoxide (DMSO) and lansoprazole to see how well it could prevent acute acid reflux esophagitis. While we found that curcumin did show some preventative effects—reducing esophagitis formation by about 52.5%—it was less effective than lansoprazole, which blocked reflux by nearly 71%.
Interestingly, when combined with DMSO, curcumin helped lower the severity of chronic esophagitis to levels similar to those seen with lansoprazole. Although curcumin alone couldn’t prevent chronic reflux esophagitis, its benefits were notable, especially in reducing neutrophil infiltration compared to the control group. However, lansoprazole seemed to worsen some histopathological changes.
Overall, while curcumin isn't as powerful as lansoprazole for acute reflux, it is particularly promising in cases of mixed reflux esophagitis and is thought to work due to its antioxidant and anti-inflammatory properties.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Reviews
8.2
4.8
Limited reflux relief
So far so good; it might be helping with general inflammation. However, it hasn't yet alleviated my reflux as I hoped. It can stain clothing yellow, yet it has had no negative effects.
