' 
![]()
SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.5
USERS' SCORE
Good
Based on 2 Reviews
8.6
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Turmeric ExtractCurcuma longa (Rhizome)(95% [475 mg] Total Curcuminoids)
500 mg
†
Top Medical Research Studies
9.5
Curcumin aids stroke recovery
Curcumin protects against cerebral ischemia-reperfusion injury in rats by attenuating oxidative stress and inflammation: A meta-analysis and mechanism exploration.
Directly related to stroke treatment.
We explored how curcumin, a compound found in turmeric, may help protect the brain from damage caused by stroke. The study we reviewed involved an in-depth analysis, aggregating data from various experiments on rats that experienced cerebral ischemia-reperfusion injury (CIRI), which mimics the conditions of a stroke.
Our findings indicated that curcumin significantly improved neurological outcomes in these animals. We observed a marked reduction in neurological deficit scores, infarct volumes, and brain water content after curcumin treatment. This suggests that curcumin not only helps the brain recover but might also reduce damage during a stroke.
Additionally, the analysis revealed that curcumin enhances the body’s antioxidant defenses while decreasing harmful inflammatory markers. We found increases in beneficial substances like superoxide dismutase and glutathione, alongside decreases in reactive oxygen species and pro-inflammatory cytokines.
Subgroup analyses hinted that the effectiveness of curcumin could vary based on the dosage used. Overall, our exploration supports the potential of curcumin as a neuroprotective agent in stroke treatment, though further research is needed to solidify its practical applications in stroke therapy.
Our findings indicated that curcumin significantly improved neurological outcomes in these animals. We observed a marked reduction in neurological deficit scores, infarct volumes, and brain water content after curcumin treatment. This suggests that curcumin not only helps the brain recover but might also reduce damage during a stroke.
Additionally, the analysis revealed that curcumin enhances the body’s antioxidant defenses while decreasing harmful inflammatory markers. We found increases in beneficial substances like superoxide dismutase and glutathione, alongside decreases in reactive oxygen species and pro-inflammatory cytokines.
Subgroup analyses hinted that the effectiveness of curcumin could vary based on the dosage used. Overall, our exploration supports the potential of curcumin as a neuroprotective agent in stroke treatment, though further research is needed to solidify its practical applications in stroke therapy.
Read More
9
Curcumin nanoparticles improve stroke recovery
Curcumin nanogel and its efficacy against oxidative stress and inflammation in rat models of ischemic stroke.
High relevance to stroke treatment
We explored the potential of curcumin nanoparticles, a compound derived from turmeric, as a protective treatment against brain damage in ischemic stroke. By developing and testing these nanoparticles in a rat model, we focused on their ability to enhance motor functions, muscle strength, and antioxidant enzyme activity.
Our results were promising. The curcumin nanoparticles not only showed a stable physical structure, with a zeta potential of -55 ± 13.5 mV and an average particle size of 51.40 ± 21.70 nm, but they also significantly improved various health markers associated with stroke. Specifically, treatment with these nanoparticles led to noticeable improvements in motor functions and muscle strength.
Additionally, we observed that the nanoparticles boosted the activity of vital antioxidant enzymes, which help reduce oxidative stress and inflammation in the brain following a stroke. This indicates a significant neuroprotective effect of curcumin nanoparticles, validating their potential as a therapeutic option for managing ischemic stroke.
Our results were promising. The curcumin nanoparticles not only showed a stable physical structure, with a zeta potential of -55 ± 13.5 mV and an average particle size of 51.40 ± 21.70 nm, but they also significantly improved various health markers associated with stroke. Specifically, treatment with these nanoparticles led to noticeable improvements in motor functions and muscle strength.
Additionally, we observed that the nanoparticles boosted the activity of vital antioxidant enzymes, which help reduce oxidative stress and inflammation in the brain following a stroke. This indicates a significant neuroprotective effect of curcumin nanoparticles, validating their potential as a therapeutic option for managing ischemic stroke.
Read More
8
Curcumin aids stroke recovery mechanisms
Curcumin Regulates Microglia Polarization to Alleviate Ischemic Stroke by Targeting microRNA-205-5p/Kruppel-Like Factor 2 (KLF2)/Activating Transcription Factor 2 (ATF2) Axis.
Directly assessed curcumin's benefits
We investigated how curcumin, a compound found in turmeric, may impact recovery after an ischemic stroke—when blood flow to the brain is obstructed. To do this, we created models both in living mice and in brain cells exposed to conditions mimicking a stroke. Through a series of tests, we measured the health of the brain and the response of specific immune cells called microglia that play a significant role in recovery.
Our findings revealed that curcumin appears to help reduce brain damage after an ischemic stroke by encouraging microglia to adopt a protective M2 state, which is vital for healing. Interestingly, we found that curcumin led to lower levels of a specific microRNA, known as miR-205-5p, in stroke-affected mice. We noted that when miR-205-5p was reduced, it seemed to enhance the beneficial M2 polarization of microglia under stress, mimicking the effects seen with curcumin treatment.
Additionally, the study showed that an interplay exists between miR-205-5p, Kruppel-like factor 2 (KLF2), and activating transcription factor 2 (ATF2), where higher levels of miR-205-5p could hinder the protective response that curcumin promotes. Overall, curcumin’s capacity to lessen the detrimental effects of this microRNA is pivotal in enhancing the brain’s recovery after a stroke.
Our findings revealed that curcumin appears to help reduce brain damage after an ischemic stroke by encouraging microglia to adopt a protective M2 state, which is vital for healing. Interestingly, we found that curcumin led to lower levels of a specific microRNA, known as miR-205-5p, in stroke-affected mice. We noted that when miR-205-5p was reduced, it seemed to enhance the beneficial M2 polarization of microglia under stress, mimicking the effects seen with curcumin treatment.
Additionally, the study showed that an interplay exists between miR-205-5p, Kruppel-like factor 2 (KLF2), and activating transcription factor 2 (ATF2), where higher levels of miR-205-5p could hinder the protective response that curcumin promotes. Overall, curcumin’s capacity to lessen the detrimental effects of this microRNA is pivotal in enhancing the brain’s recovery after a stroke.
Read More
Most Useful Reviews
8.8
Improved bowel regularity
It is a fantastic product! I initially purchased this for my husband, as I learned that turmeric may assist stroke patients. Afterward, I began taking it too and found it helps me detox. I have regular bowel movements after every meal, which makes me feel great. It has also benefited my husband, who had constipation issues, becoming more regular up to twice daily.
Read More
9.5
Immune system boost
This is one of the best curcumin products. I bought it for my mother after her stroke and for preventive purposes. Curcumin is a powerful antioxidant that strengthens the immune system. I've taken one capsule daily with no side effects. It reduces inflammation and lowers C-reactive protein. The price is reasonable too.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.5
9.5
Curcumin aids stroke recovery
Curcumin protects against cerebral ischemia-reperfusion injury in rats by attenuating oxidative stress and inflammation: A meta-analysis and mechanism exploration.
Directly related to stroke treatment.
We explored how curcumin, a compound found in turmeric, may help protect the brain from damage caused by stroke. The study we reviewed involved an in-depth analysis, aggregating data from various experiments on rats that experienced cerebral ischemia-reperfusion injury (CIRI), which mimics the conditions of a stroke.
Our findings indicated that curcumin significantly improved neurological outcomes in these animals. We observed a marked reduction in neurological deficit scores, infarct volumes, and brain water content after curcumin treatment. This suggests that curcumin not only helps the brain recover but might also reduce damage during a stroke.
Additionally, the analysis revealed that curcumin enhances the body’s antioxidant defenses while decreasing harmful inflammatory markers. We found increases in beneficial substances like superoxide dismutase and glutathione, alongside decreases in reactive oxygen species and pro-inflammatory cytokines.
Subgroup analyses hinted that the effectiveness of curcumin could vary based on the dosage used. Overall, our exploration supports the potential of curcumin as a neuroprotective agent in stroke treatment, though further research is needed to solidify its practical applications in stroke therapy.
Our findings indicated that curcumin significantly improved neurological outcomes in these animals. We observed a marked reduction in neurological deficit scores, infarct volumes, and brain water content after curcumin treatment. This suggests that curcumin not only helps the brain recover but might also reduce damage during a stroke.
Additionally, the analysis revealed that curcumin enhances the body’s antioxidant defenses while decreasing harmful inflammatory markers. We found increases in beneficial substances like superoxide dismutase and glutathione, alongside decreases in reactive oxygen species and pro-inflammatory cytokines.
Subgroup analyses hinted that the effectiveness of curcumin could vary based on the dosage used. Overall, our exploration supports the potential of curcumin as a neuroprotective agent in stroke treatment, though further research is needed to solidify its practical applications in stroke therapy.
Read More
9
Curcumin gel aids stroke recovery
Curcumin loaded hydrogel with double ROS-scavenging effect regulates microglia polarization to promote poststroke rehabilitation.
Promising therapeutic implications
We explored how a curcumin-loaded hydrogel can affect recovery after a stroke. This innovative gel not only includes curcumin, a compound from turmeric known for its anti-inflammatory properties, but also has a unique ability to respond to reactive oxygen species (ROS) in the body. By neutralizing these harmful molecules, the gel releases curcumin in a targeted manner.
In our observations, this release helps to combat inflammation in microglia, the brain's immune cells, by changing their behavior. We saw that the gel reduced harmful signs of inflammation, while also promoting protective markers in brain cells. This dual effect creates a more favorable environment for recovery in stroke-affected areas of the brain.
When we looked at the effects in stroke mice, those treated with the hydrogel showed better motor function recovery than those who weren’t treated. The gel helped enhance neuroplasticity, which is crucial for repairing and reforming brain connections that are often damaged during a stroke.
Overall, our findings suggest that this curcumin gel holds significant promise for helping stroke patients recover, making it a potential option for future clinical applications.
In our observations, this release helps to combat inflammation in microglia, the brain's immune cells, by changing their behavior. We saw that the gel reduced harmful signs of inflammation, while also promoting protective markers in brain cells. This dual effect creates a more favorable environment for recovery in stroke-affected areas of the brain.
When we looked at the effects in stroke mice, those treated with the hydrogel showed better motor function recovery than those who weren’t treated. The gel helped enhance neuroplasticity, which is crucial for repairing and reforming brain connections that are often damaged during a stroke.
Overall, our findings suggest that this curcumin gel holds significant promise for helping stroke patients recover, making it a potential option for future clinical applications.
Read More
9
Turmeric may aid stroke recovery
Curcumin-primed olfactory mucosa-derived mesenchymal stem cells mitigate cerebral ischemia/reperfusion injury-induced neuronal PANoptosis by modulating microglial polarization.
Supports turmeric's therapeutic potential
Exploring the link between turmeric and stroke, we looked at how curcumin, a key compound in turmeric, impacts brain injuries caused by a lack of blood flow. By creating both in vivo and in vitro models of cerebral ischemia-reperfusion injury in mice, we delved into the role of curcumin-prepped olfactory mucosa-derived mesenchymal stem cells (OM-MSCs) in combating neuron death.
Our findings revealed that PANoptosis, a type of cell death, occurs in neurons following stroke-like conditions. Notably, curcumin preconditioning improved the protective effects of OM-MSCs against inflammation by altering microglial polarization. This was achieved through the upregulation of miRNA-423-5p.
Ultimately, we see promise in using a combination of curcumin and OM-MSCs to reduce neuronal death from strokes. This research opens doors for potential treatments in the future.
Our findings revealed that PANoptosis, a type of cell death, occurs in neurons following stroke-like conditions. Notably, curcumin preconditioning improved the protective effects of OM-MSCs against inflammation by altering microglial polarization. This was achieved through the upregulation of miRNA-423-5p.
Ultimately, we see promise in using a combination of curcumin and OM-MSCs to reduce neuronal death from strokes. This research opens doors for potential treatments in the future.
Read More
9
Curcumin nanoparticles improve stroke recovery
Curcumin nanogel and its efficacy against oxidative stress and inflammation in rat models of ischemic stroke.
High relevance to stroke treatment
We explored the potential of curcumin nanoparticles, a compound derived from turmeric, as a protective treatment against brain damage in ischemic stroke. By developing and testing these nanoparticles in a rat model, we focused on their ability to enhance motor functions, muscle strength, and antioxidant enzyme activity.
Our results were promising. The curcumin nanoparticles not only showed a stable physical structure, with a zeta potential of -55 ± 13.5 mV and an average particle size of 51.40 ± 21.70 nm, but they also significantly improved various health markers associated with stroke. Specifically, treatment with these nanoparticles led to noticeable improvements in motor functions and muscle strength.
Additionally, we observed that the nanoparticles boosted the activity of vital antioxidant enzymes, which help reduce oxidative stress and inflammation in the brain following a stroke. This indicates a significant neuroprotective effect of curcumin nanoparticles, validating their potential as a therapeutic option for managing ischemic stroke.
Our results were promising. The curcumin nanoparticles not only showed a stable physical structure, with a zeta potential of -55 ± 13.5 mV and an average particle size of 51.40 ± 21.70 nm, but they also significantly improved various health markers associated with stroke. Specifically, treatment with these nanoparticles led to noticeable improvements in motor functions and muscle strength.
Additionally, we observed that the nanoparticles boosted the activity of vital antioxidant enzymes, which help reduce oxidative stress and inflammation in the brain following a stroke. This indicates a significant neuroprotective effect of curcumin nanoparticles, validating their potential as a therapeutic option for managing ischemic stroke.
Read More
9
Turmeric helps post-stroke shoulder pain
Clinical effect of acupoint application with turmeric blistering moxibustion plaster on post-stroke hemiplegic shoulder pain.
Moderate relevance to turmeric effectiveness
We observed how turmeric, in the form of blistering moxibustion plaster, could help alleviate shoulder pain in patients suffering from post-stroke hemiplegia. In the study, 82 patients were divided into two groups: one received traditional care, while the other also benefited from the turmeric treatment applied at specific acupoints. This treatment involved daily therapy where the plaster was applied for six hours, five times a week, over a span of two weeks.
Over the course of the study, we measured pain levels using a visual analogue scale, assessed shoulder range of motion (ROM), and gauged motor function in the upper limbs with the Fugl-Meyer assessment. The results indicated that patients receiving the turmeric moxibustion treatment reported less shoulder pain, improved range of motion, and better overall motor function compared to those who only received standard care.
Overall, our findings suggest that incorporating turmeric moxibustion could be beneficial for individuals experiencing shoulder pain after a stroke. However, it’s essential to note that since the treatment involved multiple therapies, the specific impact of turmeric alone remains somewhat unclear.
Over the course of the study, we measured pain levels using a visual analogue scale, assessed shoulder range of motion (ROM), and gauged motor function in the upper limbs with the Fugl-Meyer assessment. The results indicated that patients receiving the turmeric moxibustion treatment reported less shoulder pain, improved range of motion, and better overall motor function compared to those who only received standard care.
Overall, our findings suggest that incorporating turmeric moxibustion could be beneficial for individuals experiencing shoulder pain after a stroke. However, it’s essential to note that since the treatment involved multiple therapies, the specific impact of turmeric alone remains somewhat unclear.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.6
9.5
Immune system boost
This is one of the best curcumin products. I bought it for my mother after her stroke and for preventive purposes. Curcumin is a powerful antioxidant that strengthens the immune system. I've taken one capsule daily with no side effects. It reduces inflammation and lowers C-reactive protein. The price is reasonable too.
Read More
8.8
Improved bowel regularity
It is a fantastic product! I initially purchased this for my husband, as I learned that turmeric may assist stroke patients. Afterward, I began taking it too and found it helps me detox. I have regular bowel movements after every meal, which makes me feel great. It has also benefited my husband, who had constipation issues, becoming more regular up to twice daily.
Read More
