Overview
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.3
USERS' SCORE
Good
Based on 7 Reviews
8.5
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
MethylSulfonylMethane (MSM)
1,000 mg
†
Top Medical Research Studies
7
We explored the challenges faced by men who have sex with men (MSM) regarding anal cancer treatment in Liberia. With limited access to screening and care for anal cancers, we aimed to investigate whether a screen-triage-treat approach could effectively help identify and manage anal high-grade squamous intraepithelial lesions (aHSIL) within this vulnerable population.
In our study, we collaborated with local organizations to gather data from MSM and transgender individuals. Participants were recruited and engaged in self-swabbing to test for high-risk human papillomavirus (HPV), alongside HIV testing. Those who tested positive for aHSIL were offered further evaluation and treatment using high-resolution anoscopy and infrared coagulation.
Among 110 participants, a significant number turned out to be living with HIV, and nearly half tested positive for high-risk HPV. This indicates a notable health concern. While 68% of those who tested positive opted for further procedures, we found that this model effectively presented a potential solution for identifying anal cancer risks and can work in a low-resource environment.
Overall, our findings suggest that implementing a screen-triage-treat model shows promise for reducing anal cancer incidence among MSM in Liberia. This approach, previously successful in cervical cancer management, might become a crucial tool in cancer prevention strategies for similar low- and middle-income countries.
In our study, we collaborated with local organizations to gather data from MSM and transgender individuals. Participants were recruited and engaged in self-swabbing to test for high-risk human papillomavirus (HPV), alongside HIV testing. Those who tested positive for aHSIL were offered further evaluation and treatment using high-resolution anoscopy and infrared coagulation.
Among 110 participants, a significant number turned out to be living with HIV, and nearly half tested positive for high-risk HPV. This indicates a notable health concern. While 68% of those who tested positive opted for further procedures, we found that this model effectively presented a potential solution for identifying anal cancer risks and can work in a low-resource environment.
Overall, our findings suggest that implementing a screen-triage-treat model shows promise for reducing anal cancer incidence among MSM in Liberia. This approach, previously successful in cervical cancer management, might become a crucial tool in cancer prevention strategies for similar low- and middle-income countries.
Read More
5
We investigated the effectiveness and safety of electrocautery ablation for treating high-grade squamous intraepithelial lesions (HSILs) in men who have sex with men (MSM), including those living with HIV. Our study included 20 participants who underwent this treatment and were followed closely with high-resolution anoscopy (HRA) to monitor outcomes.
The primary goal was to see how well this approach worked at curing local HSILs after six months. While electrocautery ablation was noted to be moderately effective, we also discovered that the recurrence rates were quite high. This suggests that even with comprehensive biopsies from the anal canal, we could not fully prevent the return of these lesions.
Overall, our findings highlight that while this treatment can be helpful for MSM, the risk of recurrence is significant. More research involving larger participant groups and longer follow-ups is necessary to improve treatment outcomes. We believe it is crucial to continue refining strategies for managing HSIL to enhance the health of this community.
The primary goal was to see how well this approach worked at curing local HSILs after six months. While electrocautery ablation was noted to be moderately effective, we also discovered that the recurrence rates were quite high. This suggests that even with comprehensive biopsies from the anal canal, we could not fully prevent the return of these lesions.
Overall, our findings highlight that while this treatment can be helpful for MSM, the risk of recurrence is significant. More research involving larger participant groups and longer follow-ups is necessary to improve treatment outcomes. We believe it is crucial to continue refining strategies for managing HSIL to enhance the health of this community.
Read More
7
We investigated the effects of methanolic extracts from the fruit of Meyna spinosa on cancer cells. Our findings highlighted that both the methanolic extract and the ethyl acetate extract displayed antiproliferative properties, particularly against A549 and MCF7 cancer cell lines.
As we increased the concentration of these extracts and the duration of exposure, we observed a consistent reduction in cell viability, indicating that these extracts may inhibit cancer growth. Moreover, the extracts showed promising antioxidant activity which suggests additional mechanisms at play in potentially combating cancer.
Importantly, while these results are encouraging, they stem from laboratory observations, and further research would be necessary to translate these effects into clinical applications or comprehensive treatment options for cancer patients. Overall, our analysis gives a glimpse into the potential of Meyna spinosa fruit extracts in cancer therapy but also underscores the need for more studies to confirm these findings.
As we increased the concentration of these extracts and the duration of exposure, we observed a consistent reduction in cell viability, indicating that these extracts may inhibit cancer growth. Moreover, the extracts showed promising antioxidant activity which suggests additional mechanisms at play in potentially combating cancer.
Importantly, while these results are encouraging, they stem from laboratory observations, and further research would be necessary to translate these effects into clinical applications or comprehensive treatment options for cancer patients. Overall, our analysis gives a glimpse into the potential of Meyna spinosa fruit extracts in cancer therapy but also underscores the need for more studies to confirm these findings.
Read More
Most Useful Reviews
9
Improves recovery and health
129 people found this helpful
Methylsulfonylmethane (MSM) is excellent for my ballet training as it supports my joints and aids recovery. The effects are tangible; it's best taken with silicon supplements. MSM not only helps with joint pain and cholesterol levels but also possesses anti-cancer properties, boosts immunity, detoxifies the liver, promotes normal blood levels, and enhances brain function.
Read More
9
Essential for cancer diet
1 people found this helpful
The large package of MSM I've purchased is crucial in my diet and treatment plan for cancer. It aids in the absorption of vital supplements and herbs that I take, making it an essential part of my regimen.
Read More
0
No effect on cancer
3 people found this helpful
Works. I started taking this due to a car accident that left me limping on a damaged knee. I no longer limp; I did not have knee surgery, and the pain in my hands has gone. Four stars instead of five is for the cancer aspect, as the product does not provide the percentage of organic sulphur in it. It has had no effect on my skin cancer problem.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.3
- All Researches
7
We investigated the effects of methanolic extracts from the fruit of Meyna spinosa on cancer cells. Our findings highlighted that both the methanolic extract and the ethyl acetate extract displayed antiproliferative properties, particularly against A549 and MCF7 cancer cell lines.
As we increased the concentration of these extracts and the duration of exposure, we observed a consistent reduction in cell viability, indicating that these extracts may inhibit cancer growth. Moreover, the extracts showed promising antioxidant activity which suggests additional mechanisms at play in potentially combating cancer.
Importantly, while these results are encouraging, they stem from laboratory observations, and further research would be necessary to translate these effects into clinical applications or comprehensive treatment options for cancer patients. Overall, our analysis gives a glimpse into the potential of Meyna spinosa fruit extracts in cancer therapy but also underscores the need for more studies to confirm these findings.
As we increased the concentration of these extracts and the duration of exposure, we observed a consistent reduction in cell viability, indicating that these extracts may inhibit cancer growth. Moreover, the extracts showed promising antioxidant activity which suggests additional mechanisms at play in potentially combating cancer.
Importantly, while these results are encouraging, they stem from laboratory observations, and further research would be necessary to translate these effects into clinical applications or comprehensive treatment options for cancer patients. Overall, our analysis gives a glimpse into the potential of Meyna spinosa fruit extracts in cancer therapy but also underscores the need for more studies to confirm these findings.
Read More
7
We explored the challenges faced by men who have sex with men (MSM) regarding anal cancer treatment in Liberia. With limited access to screening and care for anal cancers, we aimed to investigate whether a screen-triage-treat approach could effectively help identify and manage anal high-grade squamous intraepithelial lesions (aHSIL) within this vulnerable population.
In our study, we collaborated with local organizations to gather data from MSM and transgender individuals. Participants were recruited and engaged in self-swabbing to test for high-risk human papillomavirus (HPV), alongside HIV testing. Those who tested positive for aHSIL were offered further evaluation and treatment using high-resolution anoscopy and infrared coagulation.
Among 110 participants, a significant number turned out to be living with HIV, and nearly half tested positive for high-risk HPV. This indicates a notable health concern. While 68% of those who tested positive opted for further procedures, we found that this model effectively presented a potential solution for identifying anal cancer risks and can work in a low-resource environment.
Overall, our findings suggest that implementing a screen-triage-treat model shows promise for reducing anal cancer incidence among MSM in Liberia. This approach, previously successful in cervical cancer management, might become a crucial tool in cancer prevention strategies for similar low- and middle-income countries.
In our study, we collaborated with local organizations to gather data from MSM and transgender individuals. Participants were recruited and engaged in self-swabbing to test for high-risk human papillomavirus (HPV), alongside HIV testing. Those who tested positive for aHSIL were offered further evaluation and treatment using high-resolution anoscopy and infrared coagulation.
Among 110 participants, a significant number turned out to be living with HIV, and nearly half tested positive for high-risk HPV. This indicates a notable health concern. While 68% of those who tested positive opted for further procedures, we found that this model effectively presented a potential solution for identifying anal cancer risks and can work in a low-resource environment.
Overall, our findings suggest that implementing a screen-triage-treat model shows promise for reducing anal cancer incidence among MSM in Liberia. This approach, previously successful in cervical cancer management, might become a crucial tool in cancer prevention strategies for similar low- and middle-income countries.
Read More
5
We investigated the effectiveness and safety of electrocautery ablation for treating high-grade squamous intraepithelial lesions (HSILs) in men who have sex with men (MSM), including those living with HIV. Our study included 20 participants who underwent this treatment and were followed closely with high-resolution anoscopy (HRA) to monitor outcomes.
The primary goal was to see how well this approach worked at curing local HSILs after six months. While electrocautery ablation was noted to be moderately effective, we also discovered that the recurrence rates were quite high. This suggests that even with comprehensive biopsies from the anal canal, we could not fully prevent the return of these lesions.
Overall, our findings highlight that while this treatment can be helpful for MSM, the risk of recurrence is significant. More research involving larger participant groups and longer follow-ups is necessary to improve treatment outcomes. We believe it is crucial to continue refining strategies for managing HSIL to enhance the health of this community.
The primary goal was to see how well this approach worked at curing local HSILs after six months. While electrocautery ablation was noted to be moderately effective, we also discovered that the recurrence rates were quite high. This suggests that even with comprehensive biopsies from the anal canal, we could not fully prevent the return of these lesions.
Overall, our findings highlight that while this treatment can be helpful for MSM, the risk of recurrence is significant. More research involving larger participant groups and longer follow-ups is necessary to improve treatment outcomes. We believe it is crucial to continue refining strategies for managing HSIL to enhance the health of this community.
Read More
User Reviews
USERS' SCORE
Good
Based on 7 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
Improves recovery and health
129 people found this helpful
Methylsulfonylmethane (MSM) is excellent for my ballet training as it supports my joints and aids recovery. The effects are tangible; it's best taken with silicon supplements. MSM not only helps with joint pain and cholesterol levels but also possesses anti-cancer properties, boosts immunity, detoxifies the liver, promotes normal blood levels, and enhances brain function.
Read More
9
Essential for cancer diet
1 people found this helpful
The large package of MSM I've purchased is crucial in my diet and treatment plan for cancer. It aids in the absorption of vital supplements and herbs that I take, making it an essential part of my regimen.
Read More
0
No effect on cancer
3 people found this helpful
Works. I started taking this due to a car accident that left me limping on a damaged knee. I no longer limp; I did not have knee surgery, and the pain in my hands has gone. Four stars instead of five is for the cancer aspect, as the product does not provide the percentage of organic sulphur in it. It has had no effect on my skin cancer problem.
Read More
7.5
Slows cancer development
2 people found this helpful
Methylsulfonylmethane is utilised mainly for alleviating pain in muscles and joints. Its anti-inflammatory properties can ease severe joint pain and strengthen immunity by reducing oxidative stress. Importantly, studies suggest that MSM may slow the development of cancer cells in various organs like the liver, skin, and colon. I recommend listening to your body and ensuring you stay healthy.
Read More
9
Effective for detoxification
Doctor Three highly praises MSM for its benefits in pain relief, detoxification, and anti-cancer effectiveness. I appreciate the positive outcomes I've experienced and continue to use it.
Read More
Frequently Asked Questions
7.5
Reduces inflammation
After my family experienced cancer, we noticed significant inflammation. Since we began using MSM, the inflammation has greatly diminished. I was advised by a doctor and I plan to continue using it for its benefits.
9
Essential for cancer diet
1 people found this helpful
The large package of MSM I've purchased is crucial in my diet and treatment plan for cancer. It aids in the absorption of vital supplements and herbs that I take, making it an essential part of my regimen.
9
Improves recovery and health
129 people found this helpful
Methylsulfonylmethane (MSM) is excellent for my ballet training as it supports my joints and aids recovery. The effects are tangible; it's best taken with silicon supplements. MSM not only helps with joint pain and cholesterol levels but also possesses anti-cancer properties, boosts immunity, detoxifies the liver, promotes normal blood levels, and enhances brain function.
7.5
Slows cancer development
2 people found this helpful
Methylsulfonylmethane is utilised mainly for alleviating pain in muscles and joints. Its anti-inflammatory properties can ease severe joint pain and strengthen immunity by reducing oxidative stress. Importantly, studies suggest that MSM may slow the development of cancer cells in various organs like the liver, skin, and colon. I recommend listening to your body and ensuring you stay healthy.
5
We investigated the effectiveness and safety of electrocautery ablation for treating high-grade squamous intraepithelial lesions (HSILs) in men who have sex with men (MSM), including those living with HIV. Our study included 20 participants who underwent this treatment and were followed closely with high-resolution anoscopy (HRA) to monitor outcomes.
The primary goal was to see how well this approach worked at curing local HSILs after six months. While electrocautery ablation was noted to be moderately effective, we also discovered that the recurrence rates were quite high. This suggests that even with comprehensive biopsies from the anal canal, we could not fully prevent the return of these lesions.
Overall, our findings highlight that while this treatment can be helpful for MSM, the risk of recurrence is significant. More research involving larger participant groups and longer follow-ups is necessary to improve treatment outcomes. We believe it is crucial to continue refining strategies for managing HSIL to enhance the health of this community.
The primary goal was to see how well this approach worked at curing local HSILs after six months. While electrocautery ablation was noted to be moderately effective, we also discovered that the recurrence rates were quite high. This suggests that even with comprehensive biopsies from the anal canal, we could not fully prevent the return of these lesions.
Overall, our findings highlight that while this treatment can be helpful for MSM, the risk of recurrence is significant. More research involving larger participant groups and longer follow-ups is necessary to improve treatment outcomes. We believe it is crucial to continue refining strategies for managing HSIL to enhance the health of this community.
7
We investigated the effects of methanolic extracts from the fruit of Meyna spinosa on cancer cells. Our findings highlighted that both the methanolic extract and the ethyl acetate extract displayed antiproliferative properties, particularly against A549 and MCF7 cancer cell lines.
As we increased the concentration of these extracts and the duration of exposure, we observed a consistent reduction in cell viability, indicating that these extracts may inhibit cancer growth. Moreover, the extracts showed promising antioxidant activity which suggests additional mechanisms at play in potentially combating cancer.
Importantly, while these results are encouraging, they stem from laboratory observations, and further research would be necessary to translate these effects into clinical applications or comprehensive treatment options for cancer patients. Overall, our analysis gives a glimpse into the potential of Meyna spinosa fruit extracts in cancer therapy but also underscores the need for more studies to confirm these findings.
As we increased the concentration of these extracts and the duration of exposure, we observed a consistent reduction in cell viability, indicating that these extracts may inhibit cancer growth. Moreover, the extracts showed promising antioxidant activity which suggests additional mechanisms at play in potentially combating cancer.
Importantly, while these results are encouraging, they stem from laboratory observations, and further research would be necessary to translate these effects into clinical applications or comprehensive treatment options for cancer patients. Overall, our analysis gives a glimpse into the potential of Meyna spinosa fruit extracts in cancer therapy but also underscores the need for more studies to confirm these findings.
References
- Kitamura H, Ando N, Mizushima D, Shiojiri D, Nakamoto T, et al. Electrocautery ablation therapy for anal intraepithelial carcinoma with high-resolution anoscopy. J Infect Chemother. 2025;31:102608. doi:10.1016/j.jiac.2025.102608
- Boruah JLH, Gogoi M, Famhawite V, Barman D, Das DJ, et al. Phytochemical Characterization, Prooxidant, Antiproliferative and Anti-Inflammatory Potential of Meyna spinosa Roxb. Ex Link Ripe Fruit. Chem Biodivers. 2024. doi:10.1002/cbdv.202402342
- Reynolds CW, Lieb W, Schecter A, Gaisa MM, McGill SK, et al. Piloting of a Screen‑Triage‑Treat Surgical Approach Model for Management of Anal Cancer in Liberia. Ann Glob Health. 2024;90:75. doi:10.5334/aogh.4576
