Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 6 Reviews
8.4
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
MethylSulfonylMethane (MSM)
1,000 mg

Top Medical Research Studies

8
MSM enhances bone cell differentiation
We investigated how methylsulfonylmethane (MSM) interacts with bone morphogenetic protein 2 (BMP-2) to potentially enhance the differentiation of mesenchymal stem cells (MSCs) into osteoblasts, which are crucial for bone health. The study revealed that both MSM and BMP-2, when combined, lead to increased levels of certain proteins that aid in this process.

Observing changes in cell structure and mineral deposits helped us see the effectiveness of these treatments. The researchers noted that using MSM alongside BMP-2 significantly boosted the differentiation of MSCs into osteoblasts compared to using either treatment on its own.

Moreover, the findings indicated that the combination treatment elevated the expression of genes related to osteoblast differentiation. This suggests that MSM could play a beneficial role in promoting bone formation when used with BMP-2. However, it is essential to consider that the study's focus on the combination makes it challenging to assess MSM's isolated impact on osteoporosis directly.
Read More

Most Useful Reviews

9
Menopause support
This is good for osteoporosis and essential during menopause.
Read More
9
Walking freely
Excellent for osteoporosis! My mother, who struggled to walk due to multiple fractures sustained in a traffic accident, takes MSM and now walks freely.
Read More
7.5
Mobility improvement
1 people found this helpful
I give this to my mother, who has osteoporosis. She also takes glucosamine and chondroitin occasionally. I am pleased with the results; at 80 and after a femoral neck fracture, she can now walk on her own.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
  • All Researches
8
MSM enhances bone cell differentiation
We investigated how methylsulfonylmethane (MSM) interacts with bone morphogenetic protein 2 (BMP-2) to potentially enhance the differentiation of mesenchymal stem cells (MSCs) into osteoblasts, which are crucial for bone health. The study revealed that both MSM and BMP-2, when combined, lead to increased levels of certain proteins that aid in this process.

Observing changes in cell structure and mineral deposits helped us see the effectiveness of these treatments. The researchers noted that using MSM alongside BMP-2 significantly boosted the differentiation of MSCs into osteoblasts compared to using either treatment on its own.

Moreover, the findings indicated that the combination treatment elevated the expression of genes related to osteoblast differentiation. This suggests that MSM could play a beneficial role in promoting bone formation when used with BMP-2. However, it is essential to consider that the study's focus on the combination makes it challenging to assess MSM's isolated impact on osteoporosis directly.
Read More

User Reviews

USERS' SCORE
Good
Based on 6 Reviews
8.4
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Menopause support
This is good for osteoporosis and essential during menopause.
Read More
9
Walking freely
Excellent for osteoporosis! My mother, who struggled to walk due to multiple fractures sustained in a traffic accident, takes MSM and now walks freely.
Read More
7.5
Mobility improvement
1 people found this helpful
I give this to my mother, who has osteoporosis. She also takes glucosamine and chondroitin occasionally. I am pleased with the results; at 80 and after a femoral neck fracture, she can now walk on her own.
Read More
7.5
Collagen production
1 people found this helpful
This organic sulfur product aids in collagen production. Just one pill a day, preferably with glucosamine, ginkgo biloba, and vitamin D, is sufficient for those experiencing weakness, osteoporosis, or knee issues.
Read More
9
Prevention effectiveness
An excellent drug for preventing osteoporosis and for collagen production.
Read More

Frequently Asked Questions

9
Walking freely
Excellent for osteoporosis! My mother, who struggled to walk due to multiple fractures sustained in a traffic accident, takes MSM and now walks freely.
7.5
Mobility improvement
1 people found this helpful
I give this to my mother, who has osteoporosis. She also takes glucosamine and chondroitin occasionally. I am pleased with the results; at 80 and after a femoral neck fracture, she can now walk on her own.
7.5
Collagen production
1 people found this helpful
This organic sulfur product aids in collagen production. Just one pill a day, preferably with glucosamine, ginkgo biloba, and vitamin D, is sufficient for those experiencing weakness, osteoporosis, or knee issues.
7.5
Osteoporosis improvement
My mother has a bad knee, but her condition improved after taking this. Her osteoporosis has also significantly improved, though I believe this is likely due to the treatment.
9
Prevention effectiveness
An excellent drug for preventing osteoporosis and for collagen production.
9
Menopause support
This is good for osteoporosis and essential during menopause.
8
MSM enhances bone cell differentiation
We investigated how methylsulfonylmethane (MSM) interacts with bone morphogenetic protein 2 (BMP-2) to potentially enhance the differentiation of mesenchymal stem cells (MSCs) into osteoblasts, which are crucial for bone health. The study revealed that both MSM and BMP-2, when combined, lead to increased levels of certain proteins that aid in this process.

Observing changes in cell structure and mineral deposits helped us see the effectiveness of these treatments. The researchers noted that using MSM alongside BMP-2 significantly boosted the differentiation of MSCs into osteoblasts compared to using either treatment on its own.

Moreover, the findings indicated that the combination treatment elevated the expression of genes related to osteoblast differentiation. This suggests that MSM could play a beneficial role in promoting bone formation when used with BMP-2. However, it is essential to consider that the study's focus on the combination makes it challenging to assess MSM's isolated impact on osteoporosis directly.

References

  1. Kim DN, Joung YH, Darvin P, Kang DY, Sp N, et al. Methylsulfonylmethane enhances BMP‑2‑induced osteoblast differentiation in mesenchymal stem cells. Mol Med Rep. 2016;14:460. doi:10.3892/mmr.2016.5274
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