Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.2
USERS' SCORE
Good
Based on 10 Reviews
8.1
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Zinc (as Zinc L-Methionine Sulfate)
15 mg
136%
Copper (as Gluconate)
1 mg
111%
Top Medical Research Studies
8
Zinc conditioner benefits scalp psoriasis
We delved into the effectiveness of a zinc-based hair conditioner specifically designed for treating scalp psoriasis. This study was a well-structured clinical trial involving 211 participants, where individuals were divided into three groups: those receiving the specialized zinc treatment, a placebo, and a control group given calcipotriol ointment. Remarkably, the trial was multicenter and observed-blind, which adds credibility to the findings.
Our results revealed that the zinc conditioner led to a 39% disease control rate after four weeks, compared to 25% for the placebo and 37% for the calcipotriol ointment group. This means that the zinc treatment significantly outperformed the placebo while being on par with the active control variant. In essence, those using the zinc product experienced better management of their scalp psoriasis than those using a non-active alternative.
Overall, our findings highlight that a supramolecular active zinc antidandruff formulation is not just effective for treating scalp psoriasis but also helps in maintaining results over time and potentially preventing future flare-ups. This offers a promising new avenue for patients seeking relief from this chronic condition.
Our results revealed that the zinc conditioner led to a 39% disease control rate after four weeks, compared to 25% for the placebo and 37% for the calcipotriol ointment group. This means that the zinc treatment significantly outperformed the placebo while being on par with the active control variant. In essence, those using the zinc product experienced better management of their scalp psoriasis than those using a non-active alternative.
Overall, our findings highlight that a supramolecular active zinc antidandruff formulation is not just effective for treating scalp psoriasis but also helps in maintaining results over time and potentially preventing future flare-ups. This offers a promising new avenue for patients seeking relief from this chronic condition.
Read More
9
We evaluated the role of zinc treatment in addressing skin lesions that resemble psoriasis. Our focus was on a teenage boy who displayed characteristic symptoms of acrodermatitis enteropathica (AE) along with low serum zinc levels. Over time, his condition progressed into more widespread pustular psoriasis-like symptoms.
Notably, after initiating zinc supplementation, we observed a rapid improvement in his skin conditions. This led us to ponder whether zinc malabsorption might be a common factor triggering both AE and psoriasis-like skin issues. By restoring zinc levels, we believe we may have found a straightforward yet effective approach to manage these overlapping skin manifestations.
Overall, our findings suggest that maintaining a balanced zinc homeostasis could help alleviate symptoms for those affected by both AE and psoriasiform lesions.
Notably, after initiating zinc supplementation, we observed a rapid improvement in his skin conditions. This led us to ponder whether zinc malabsorption might be a common factor triggering both AE and psoriasis-like skin issues. By restoring zinc levels, we believe we may have found a straightforward yet effective approach to manage these overlapping skin manifestations.
Overall, our findings suggest that maintaining a balanced zinc homeostasis could help alleviate symptoms for those affected by both AE and psoriasiform lesions.
Read More
9
We aimed to explore the effectiveness of zinc phthalocyanine, especially its sugar-conjugated forms, in treating psoriasis. This skin condition affects millions and is characterized by rapid skin cell growth and inflammation. Through our research, we synthesized both protected and unprotected versions of these conjugates to see how well they worked against psoriasis-related symptoms.
In tests with cells designed to mimic psoriasis, we found that the protected glucose-zinc phthalocyanine (Glu-4-ZnPc-P) showed the strongest phototoxic effects. It was significantly more effective than other variations, demonstrating its potential as a targeted therapy. When we stimulated cells with IL-17A, a key player in psoriasis, we observed that this enhanced the uptake of the unprotected variant, suggesting an interesting interaction that could enhance treatment efficacy.
Additionally, our tests in a psoriasis-like model demonstrated that using Glu-4-ZnPc-P led to marked improvements in skin condition and reduced inflammation, indicating its promising role in photodynamic therapy. Overall, our findings underscore the potential of sugar-conjugated zinc phthalocyanine as a novel treatment avenue for psoriasis, paving the way for future clinical studies.
In tests with cells designed to mimic psoriasis, we found that the protected glucose-zinc phthalocyanine (Glu-4-ZnPc-P) showed the strongest phototoxic effects. It was significantly more effective than other variations, demonstrating its potential as a targeted therapy. When we stimulated cells with IL-17A, a key player in psoriasis, we observed that this enhanced the uptake of the unprotected variant, suggesting an interesting interaction that could enhance treatment efficacy.
Additionally, our tests in a psoriasis-like model demonstrated that using Glu-4-ZnPc-P led to marked improvements in skin condition and reduced inflammation, indicating its promising role in photodynamic therapy. Overall, our findings underscore the potential of sugar-conjugated zinc phthalocyanine as a novel treatment avenue for psoriasis, paving the way for future clinical studies.
Read More
Most Useful Reviews
7.5
Psoriasis cleared up
24 people found this helpful
I believe my Jarrow Colostrum has helped get rid of my hand and foot psoriasis. After I started taking it, my plaques began to disappear. I also used a new all-natural cream, so it could be a combination of both. Regardless, I am very happy, as my psoriasis has cleared up, and there have been no side effects.
Read More
9
Calms psoriasis
1 people found this helpful
Excellent dosage for both children and adults! I've used it before; I give my children a smaller dose when they fall ill. I regularly consume vitamin C, D, and zinc throughout autumn and winter, and I've noticed clearer skin on my face. My psoriasis on the scalp has calmed down significantly, relieving me from purchasing costly shampoos and gels for treatment.
Read More
10
Psoriasis disappeared
Excellent for psoriasis. My psoriasis has disappeared after suffering for years. This is Dr. Karim Ali's prescription, may he be rewarded. I take one pill on an empty stomach each morning.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.2
- All Researches
9
We evaluated the role of zinc treatment in addressing skin lesions that resemble psoriasis. Our focus was on a teenage boy who displayed characteristic symptoms of acrodermatitis enteropathica (AE) along with low serum zinc levels. Over time, his condition progressed into more widespread pustular psoriasis-like symptoms.
Notably, after initiating zinc supplementation, we observed a rapid improvement in his skin conditions. This led us to ponder whether zinc malabsorption might be a common factor triggering both AE and psoriasis-like skin issues. By restoring zinc levels, we believe we may have found a straightforward yet effective approach to manage these overlapping skin manifestations.
Overall, our findings suggest that maintaining a balanced zinc homeostasis could help alleviate symptoms for those affected by both AE and psoriasiform lesions.
Notably, after initiating zinc supplementation, we observed a rapid improvement in his skin conditions. This led us to ponder whether zinc malabsorption might be a common factor triggering both AE and psoriasis-like skin issues. By restoring zinc levels, we believe we may have found a straightforward yet effective approach to manage these overlapping skin manifestations.
Overall, our findings suggest that maintaining a balanced zinc homeostasis could help alleviate symptoms for those affected by both AE and psoriasiform lesions.
Read More
9
We aimed to explore the effectiveness of zinc phthalocyanine, especially its sugar-conjugated forms, in treating psoriasis. This skin condition affects millions and is characterized by rapid skin cell growth and inflammation. Through our research, we synthesized both protected and unprotected versions of these conjugates to see how well they worked against psoriasis-related symptoms.
In tests with cells designed to mimic psoriasis, we found that the protected glucose-zinc phthalocyanine (Glu-4-ZnPc-P) showed the strongest phototoxic effects. It was significantly more effective than other variations, demonstrating its potential as a targeted therapy. When we stimulated cells with IL-17A, a key player in psoriasis, we observed that this enhanced the uptake of the unprotected variant, suggesting an interesting interaction that could enhance treatment efficacy.
Additionally, our tests in a psoriasis-like model demonstrated that using Glu-4-ZnPc-P led to marked improvements in skin condition and reduced inflammation, indicating its promising role in photodynamic therapy. Overall, our findings underscore the potential of sugar-conjugated zinc phthalocyanine as a novel treatment avenue for psoriasis, paving the way for future clinical studies.
In tests with cells designed to mimic psoriasis, we found that the protected glucose-zinc phthalocyanine (Glu-4-ZnPc-P) showed the strongest phototoxic effects. It was significantly more effective than other variations, demonstrating its potential as a targeted therapy. When we stimulated cells with IL-17A, a key player in psoriasis, we observed that this enhanced the uptake of the unprotected variant, suggesting an interesting interaction that could enhance treatment efficacy.
Additionally, our tests in a psoriasis-like model demonstrated that using Glu-4-ZnPc-P led to marked improvements in skin condition and reduced inflammation, indicating its promising role in photodynamic therapy. Overall, our findings underscore the potential of sugar-conjugated zinc phthalocyanine as a novel treatment avenue for psoriasis, paving the way for future clinical studies.
Read More
8
We explored the link between zinc levels and psoriasis to understand how it might influence keratinocyte proliferation, a primary driver of this skin condition. In our investigation, we noticed that SLC35E1, a protein linked to zinc regulation, was more active in the skin cells of individuals suffering from psoriasis.
We compared the psoriasis-like symptoms in mice with and without the SLC35E1 gene, particularly after inducing skin inflammation with imiquimod (IMQ). The results showed that mice lacking SLC35E1 had milder symptoms, suggesting this protein directly influences keratinocyte growth.
On a molecular level, we discovered that SLC35E1 affects zinc ion levels in skin cells. When we reduced zinc levels, the symptoms in Slc35e1 mice improved, indicating that managing zinc could be important for treating psoriasis. We also found that patients with psoriasis had lower zinc levels in their skin. Notably, supplementing with zinc helped improve psoriasis-like symptoms in our mouse models.
Overall, this study points to zinc’s crucial role in skin health and suggests that boosting zinc levels may offer new hope for those battling psoriasis.
We compared the psoriasis-like symptoms in mice with and without the SLC35E1 gene, particularly after inducing skin inflammation with imiquimod (IMQ). The results showed that mice lacking SLC35E1 had milder symptoms, suggesting this protein directly influences keratinocyte growth.
On a molecular level, we discovered that SLC35E1 affects zinc ion levels in skin cells. When we reduced zinc levels, the symptoms in Slc35e1 mice improved, indicating that managing zinc could be important for treating psoriasis. We also found that patients with psoriasis had lower zinc levels in their skin. Notably, supplementing with zinc helped improve psoriasis-like symptoms in our mouse models.
Overall, this study points to zinc’s crucial role in skin health and suggests that boosting zinc levels may offer new hope for those battling psoriasis.
Read More
8
Zinc conditioner benefits scalp psoriasis
We delved into the effectiveness of a zinc-based hair conditioner specifically designed for treating scalp psoriasis. This study was a well-structured clinical trial involving 211 participants, where individuals were divided into three groups: those receiving the specialized zinc treatment, a placebo, and a control group given calcipotriol ointment. Remarkably, the trial was multicenter and observed-blind, which adds credibility to the findings.
Our results revealed that the zinc conditioner led to a 39% disease control rate after four weeks, compared to 25% for the placebo and 37% for the calcipotriol ointment group. This means that the zinc treatment significantly outperformed the placebo while being on par with the active control variant. In essence, those using the zinc product experienced better management of their scalp psoriasis than those using a non-active alternative.
Overall, our findings highlight that a supramolecular active zinc antidandruff formulation is not just effective for treating scalp psoriasis but also helps in maintaining results over time and potentially preventing future flare-ups. This offers a promising new avenue for patients seeking relief from this chronic condition.
Our results revealed that the zinc conditioner led to a 39% disease control rate after four weeks, compared to 25% for the placebo and 37% for the calcipotriol ointment group. This means that the zinc treatment significantly outperformed the placebo while being on par with the active control variant. In essence, those using the zinc product experienced better management of their scalp psoriasis than those using a non-active alternative.
Overall, our findings highlight that a supramolecular active zinc antidandruff formulation is not just effective for treating scalp psoriasis but also helps in maintaining results over time and potentially preventing future flare-ups. This offers a promising new avenue for patients seeking relief from this chronic condition.
Read More
7
We explored the impact of zinc on psoriasis, a condition often linked with inflammation and immune response. Our attention was drawn to zinc's ability to inhibit inflammasome activation, which can trigger harmful cell death and excessive inflammation.
In particular, we noted how zinc functions as a crucial player in regulating immune responses. By targeting a protein involved in zinc export, called SLC30A1, we observed that increasing zinc levels inside cells could inhibit the activity of caspases, enzymes that play a role in inflammation. This inhibition appears to limit the severity of inflammatory responses, making zinc a potential ally in managing psoriasis and similar conditions.
Interestingly, zinc supplementation showed promise in alleviating symptoms among those with psoriasis, alongside benefits for other inflammatory diseases like sepsis and Alzheimer’s. Although zinc may enhance treatment efficacy, we should remain cautious as the specific benefits for psoriasis treatment relative to other therapies need further clarification.
Overall, zinc emerges as a valuable option worth considering in our approach to treating conditions that involve inflammasome overactivation, including psoriasis.
In particular, we noted how zinc functions as a crucial player in regulating immune responses. By targeting a protein involved in zinc export, called SLC30A1, we observed that increasing zinc levels inside cells could inhibit the activity of caspases, enzymes that play a role in inflammation. This inhibition appears to limit the severity of inflammatory responses, making zinc a potential ally in managing psoriasis and similar conditions.
Interestingly, zinc supplementation showed promise in alleviating symptoms among those with psoriasis, alongside benefits for other inflammatory diseases like sepsis and Alzheimer’s. Although zinc may enhance treatment efficacy, we should remain cautious as the specific benefits for psoriasis treatment relative to other therapies need further clarification.
Overall, zinc emerges as a valuable option worth considering in our approach to treating conditions that involve inflammasome overactivation, including psoriasis.
Read More
User Reviews
USERS' SCORE
Good
Based on 10 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Psoriasis cleared up
24 people found this helpful
I believe my Jarrow Colostrum has helped get rid of my hand and foot psoriasis. After I started taking it, my plaques began to disappear. I also used a new all-natural cream, so it could be a combination of both. Regardless, I am very happy, as my psoriasis has cleared up, and there have been no side effects.
Read More
9
Calms psoriasis
1 people found this helpful
Excellent dosage for both children and adults! I've used it before; I give my children a smaller dose when they fall ill. I regularly consume vitamin C, D, and zinc throughout autumn and winter, and I've noticed clearer skin on my face. My psoriasis on the scalp has calmed down significantly, relieving me from purchasing costly shampoos and gels for treatment.
Read More
10
Psoriasis disappeared
Excellent for psoriasis. My psoriasis has disappeared after suffering for years. This is Dr. Karim Ali's prescription, may he be rewarded. I take one pill on an empty stomach each morning.
Read More
8
Copper balance maintained
Zinc and copper are antagonists, hence neither should be taken for prolonged periods. I have psoriasis and follow a personal treatment protocol that involves taking high doses of zinc in short courses. After this, I use the supplement to prevent copper imbalance, which is vital for the immune and nervous systems.
Read More
7.5
Relieves itching
Favorite product. I purchase it repeatedly as it assists with my psoriasis. With regular usage, it alleviates itching and redness. I also appreciate the inclusion of copper in the ingredients, eliminating the need for additional supplementation.
Read More
Frequently Asked Questions
10
Psoriasis disappeared
Excellent for psoriasis. My psoriasis has disappeared after suffering for years. This is Dr. Karim Ali's prescription, may he be rewarded. I take one pill on an empty stomach each morning.
7.5
Relieves itching
Favorite product. I purchase it repeatedly as it assists with my psoriasis. With regular usage, it alleviates itching and redness. I also appreciate the inclusion of copper in the ingredients, eliminating the need for additional supplementation.
7.5
Maintains immunity
Excellent! I have psoriasis and consume it for prevention and to support my immunity.
9
Calms psoriasis
1 people found this helpful
Excellent dosage for both children and adults! I've used it before; I give my children a smaller dose when they fall ill. I regularly consume vitamin C, D, and zinc throughout autumn and winter, and I've noticed clearer skin on my face. My psoriasis on the scalp has calmed down significantly, relieving me from purchasing costly shampoos and gels for treatment.
8
Copper balance maintained
Zinc and copper are antagonists, hence neither should be taken for prolonged periods. I have psoriasis and follow a personal treatment protocol that involves taking high doses of zinc in short courses. After this, I use the supplement to prevent copper imbalance, which is vital for the immune and nervous systems.
7.5
Skin condition improved
An excellent result with zinc, an important trace element necessary for biological processes in the body. It enhances skin conditions, particularly in the case of acne and psoriasis, promotes wound healing, boosts immunity, and improves hair structure and strength.
7
We explored the impact of zinc on psoriasis, a condition often linked with inflammation and immune response. Our attention was drawn to zinc's ability to inhibit inflammasome activation, which can trigger harmful cell death and excessive inflammation.
In particular, we noted how zinc functions as a crucial player in regulating immune responses. By targeting a protein involved in zinc export, called SLC30A1, we observed that increasing zinc levels inside cells could inhibit the activity of caspases, enzymes that play a role in inflammation. This inhibition appears to limit the severity of inflammatory responses, making zinc a potential ally in managing psoriasis and similar conditions.
Interestingly, zinc supplementation showed promise in alleviating symptoms among those with psoriasis, alongside benefits for other inflammatory diseases like sepsis and Alzheimer’s. Although zinc may enhance treatment efficacy, we should remain cautious as the specific benefits for psoriasis treatment relative to other therapies need further clarification.
Overall, zinc emerges as a valuable option worth considering in our approach to treating conditions that involve inflammasome overactivation, including psoriasis.
In particular, we noted how zinc functions as a crucial player in regulating immune responses. By targeting a protein involved in zinc export, called SLC30A1, we observed that increasing zinc levels inside cells could inhibit the activity of caspases, enzymes that play a role in inflammation. This inhibition appears to limit the severity of inflammatory responses, making zinc a potential ally in managing psoriasis and similar conditions.
Interestingly, zinc supplementation showed promise in alleviating symptoms among those with psoriasis, alongside benefits for other inflammatory diseases like sepsis and Alzheimer’s. Although zinc may enhance treatment efficacy, we should remain cautious as the specific benefits for psoriasis treatment relative to other therapies need further clarification.
Overall, zinc emerges as a valuable option worth considering in our approach to treating conditions that involve inflammasome overactivation, including psoriasis.
9
We evaluated the role of zinc treatment in addressing skin lesions that resemble psoriasis. Our focus was on a teenage boy who displayed characteristic symptoms of acrodermatitis enteropathica (AE) along with low serum zinc levels. Over time, his condition progressed into more widespread pustular psoriasis-like symptoms.
Notably, after initiating zinc supplementation, we observed a rapid improvement in his skin conditions. This led us to ponder whether zinc malabsorption might be a common factor triggering both AE and psoriasis-like skin issues. By restoring zinc levels, we believe we may have found a straightforward yet effective approach to manage these overlapping skin manifestations.
Overall, our findings suggest that maintaining a balanced zinc homeostasis could help alleviate symptoms for those affected by both AE and psoriasiform lesions.
Notably, after initiating zinc supplementation, we observed a rapid improvement in his skin conditions. This led us to ponder whether zinc malabsorption might be a common factor triggering both AE and psoriasis-like skin issues. By restoring zinc levels, we believe we may have found a straightforward yet effective approach to manage these overlapping skin manifestations.
Overall, our findings suggest that maintaining a balanced zinc homeostasis could help alleviate symptoms for those affected by both AE and psoriasiform lesions.
8
Zinc conditioner benefits scalp psoriasis
We delved into the effectiveness of a zinc-based hair conditioner specifically designed for treating scalp psoriasis. This study was a well-structured clinical trial involving 211 participants, where individuals were divided into three groups: those receiving the specialized zinc treatment, a placebo, and a control group given calcipotriol ointment. Remarkably, the trial was multicenter and observed-blind, which adds credibility to the findings.
Our results revealed that the zinc conditioner led to a 39% disease control rate after four weeks, compared to 25% for the placebo and 37% for the calcipotriol ointment group. This means that the zinc treatment significantly outperformed the placebo while being on par with the active control variant. In essence, those using the zinc product experienced better management of their scalp psoriasis than those using a non-active alternative.
Overall, our findings highlight that a supramolecular active zinc antidandruff formulation is not just effective for treating scalp psoriasis but also helps in maintaining results over time and potentially preventing future flare-ups. This offers a promising new avenue for patients seeking relief from this chronic condition.
Our results revealed that the zinc conditioner led to a 39% disease control rate after four weeks, compared to 25% for the placebo and 37% for the calcipotriol ointment group. This means that the zinc treatment significantly outperformed the placebo while being on par with the active control variant. In essence, those using the zinc product experienced better management of their scalp psoriasis than those using a non-active alternative.
Overall, our findings highlight that a supramolecular active zinc antidandruff formulation is not just effective for treating scalp psoriasis but also helps in maintaining results over time and potentially preventing future flare-ups. This offers a promising new avenue for patients seeking relief from this chronic condition.
8
We explored the link between zinc levels and psoriasis to understand how it might influence keratinocyte proliferation, a primary driver of this skin condition. In our investigation, we noticed that SLC35E1, a protein linked to zinc regulation, was more active in the skin cells of individuals suffering from psoriasis.
We compared the psoriasis-like symptoms in mice with and without the SLC35E1 gene, particularly after inducing skin inflammation with imiquimod (IMQ). The results showed that mice lacking SLC35E1 had milder symptoms, suggesting this protein directly influences keratinocyte growth.
On a molecular level, we discovered that SLC35E1 affects zinc ion levels in skin cells. When we reduced zinc levels, the symptoms in Slc35e1 mice improved, indicating that managing zinc could be important for treating psoriasis. We also found that patients with psoriasis had lower zinc levels in their skin. Notably, supplementing with zinc helped improve psoriasis-like symptoms in our mouse models.
Overall, this study points to zinc’s crucial role in skin health and suggests that boosting zinc levels may offer new hope for those battling psoriasis.
We compared the psoriasis-like symptoms in mice with and without the SLC35E1 gene, particularly after inducing skin inflammation with imiquimod (IMQ). The results showed that mice lacking SLC35E1 had milder symptoms, suggesting this protein directly influences keratinocyte growth.
On a molecular level, we discovered that SLC35E1 affects zinc ion levels in skin cells. When we reduced zinc levels, the symptoms in Slc35e1 mice improved, indicating that managing zinc could be important for treating psoriasis. We also found that patients with psoriasis had lower zinc levels in their skin. Notably, supplementing with zinc helped improve psoriasis-like symptoms in our mouse models.
Overall, this study points to zinc’s crucial role in skin health and suggests that boosting zinc levels may offer new hope for those battling psoriasis.
References
- Gong X, Gu W, Fu S, Zou G, Jiang Z. Zinc homeostasis regulates caspase activity and inflammasome activation. PLoS Pathog. 2024;20:e1012805. doi:10.1371/journal.ppat.1012805
- Wang L, Zou S, Zhu Y. Zinc Supplementation for Acrodermatitis Enteropathica Overlapped with Psoriasiform Lesions. Psoriasis (Auckl). 2024;14:175. doi:10.2147/PTT.S494519
- Makuch S, Kupczyk P, Woźniak M, Makarec A, Lipińska M, et al. In Vitro and In Vivo Antipsoriatic Efficacy of Protected and Unprotected Sugar-Zinc Phthalocyanine Conjugates. Pharmaceutics. 2024;16. doi:10.3390/pharmaceutics16060838
- Huang T, Chen S, Ding K, Zheng B, Lv W, et al. SLC35E1 promotes keratinocyte proliferation in psoriasis by regulating zinc homeostasis. Cell Death Dis. 2023;14:354. doi:10.1038/s41419-023-05874-1
- Yu C, Yu N, Jiang X, Gao X, Lv S, et al. Efficacy and safety of supramolecular active zinc in the treatment of scalp psoriasis: a multicentre, randomized, observed-blind, parallel-group, placebo- and active-controlled noninferiority trial. Clin Exp Dermatol. 2023;48:1138. doi:10.1093/ced/llad168
