' 
SCIENTIFIC SCORE
Most Likely Effective
Based on 8 Researches
7.5
USERS' SCORE
Excellent
Based on 1 Reviews
9.5
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin D (as D3 Cholecalciferol)
125 mcg (5,000 IU)
625%
Top Medical Research Studies
8
High-dose vitamin D reduces anxiety
Effects of an 8-week high-dose vitamin D supplementation on fatigue and neuropsychiatric manifestations in post-COVID syndrome: A randomized controlled trial.
Directly assesses vitamin D's impact
We conducted a study to understand how high-dose vitamin D supplementation might impact anxiety levels, particularly in patients experiencing post-COVID symptoms. In our double-blind, randomized controlled trial, we enrolled 80 individuals dealing with fatigue or neuropsychiatric issues after COVID-19.
Participants were split into two groups: one received a weekly dose of 60,000 IU of vitamin D, while the other group received a placebo. Over eight weeks, we evaluated various outcomes, including anxiety levels using the Depression, Anxiety, and Stress Scale (DASS-21).
The results were encouraging for the vitamin D group. We observed significant improvements in anxiety levels, with a notable reduction reported by participants. However, other measures related to sleep quality, depression, cognitive function, and inflammatory markers did not show similar significant changes.
Importantly, we found that the vitamin D group reported no serious adverse effects, indicating that this supplementation is generally safe. These findings suggest that high-dose vitamin D may offer substantial benefits for anxiety relief in patients recovering from COVID-19, albeit with limited effects on other symptoms.
Participants were split into two groups: one received a weekly dose of 60,000 IU of vitamin D, while the other group received a placebo. Over eight weeks, we evaluated various outcomes, including anxiety levels using the Depression, Anxiety, and Stress Scale (DASS-21).
The results were encouraging for the vitamin D group. We observed significant improvements in anxiety levels, with a notable reduction reported by participants. However, other measures related to sleep quality, depression, cognitive function, and inflammatory markers did not show similar significant changes.
Importantly, we found that the vitamin D group reported no serious adverse effects, indicating that this supplementation is generally safe. These findings suggest that high-dose vitamin D may offer substantial benefits for anxiety relief in patients recovering from COVID-19, albeit with limited effects on other symptoms.
Read More
8
Link between Vitamin D and anxiety
Association of serum vitamin D with anxiety in US adults: a cross-sectional study.
High relevance for vitamin D research
We examined if there is a connection between vitamin D levels and anxiety among US adults, utilizing data from the National Health and Nutrition Examination Survey (NHANES) conducted between 2007 and 2012. The study included over 12,000 participants and employed sophisticated statistical methods to determine the relationship between serum vitamin D and anxiety.
Our analyses revealed that higher levels of serum vitamin D were associated with a lower risk of experiencing anxiety. Specifically, we found a significant inverse relationship; as vitamin D levels increased, the likelihood of anxiety decreased. This connection remained strong even after adjusting for various factors that could influence the results.
Furthermore, smooth curve fitting techniques confirmed a negative association between vitamin D and anxiety risk. Nonetheless, while these findings are promising, we emphasize the need for further prospective studies to validate these results and fully understand the implications of vitamin D on mental health.
Our analyses revealed that higher levels of serum vitamin D were associated with a lower risk of experiencing anxiety. Specifically, we found a significant inverse relationship; as vitamin D levels increased, the likelihood of anxiety decreased. This connection remained strong even after adjusting for various factors that could influence the results.
Furthermore, smooth curve fitting techniques confirmed a negative association between vitamin D and anxiety risk. Nonetheless, while these findings are promising, we emphasize the need for further prospective studies to validate these results and fully understand the implications of vitamin D on mental health.
Read More
8
Vitamin D mitigates anxiety symptoms
Placenta-specific CYP11A1 overexpression lead to autism-like symptom in offspring with altered steroid hormone biosynthesis in the placenta-brain axis and rescued by vitamin D intervention.
Strong relevance to vitamin D effects
We explored the impact of changing levels of a specific enzyme, CYP11A1, in the placenta and how it might influence anxiety and social behavior in offspring. Using a unique mouse model, we found that higher levels of this enzyme are associated with behaviors similar to those seen in autism spectrum disorders (ASD), such as reduced social interaction and increased anxiety.
Interestingly, we observed that these anxiety-related behaviors improved significantly after administering vitamin D3. Behavioral tests, including open field and elevated plus maze assessments, showed that the mice exhibited less anxiety when given this supplement.
Additionally, our study highlighted that vitamin D3 could help correct some of the hormonal imbalances linked to CYP11A1 overexpression. Higher progesterone levels and increased inflammation were noted in the affected mice, and these issues seemed to reverse with vitamin D3 treatment.
This research underscores not only the potential role of vitamin D in managing anxiety but also suggests that examining CYP11A1 levels could be important for understanding and perhaps preventing some neurodevelopmental disorders. Overall, it appears vitamin D3 may serve as a useful tool in mitigating anxiety linked to hormonal changes during development.
Interestingly, we observed that these anxiety-related behaviors improved significantly after administering vitamin D3. Behavioral tests, including open field and elevated plus maze assessments, showed that the mice exhibited less anxiety when given this supplement.
Additionally, our study highlighted that vitamin D3 could help correct some of the hormonal imbalances linked to CYP11A1 overexpression. Higher progesterone levels and increased inflammation were noted in the affected mice, and these issues seemed to reverse with vitamin D3 treatment.
This research underscores not only the potential role of vitamin D in managing anxiety but also suggests that examining CYP11A1 levels could be important for understanding and perhaps preventing some neurodevelopmental disorders. Overall, it appears vitamin D3 may serve as a useful tool in mitigating anxiety linked to hormonal changes during development.
Read More
Most Useful Reviews
9.5
Reduced anxiety
I trust the Jarrow brand and was satisfied with their vitamin D, which I take with my family at breakfast. Coupled with K2, we have fallen ill less often, and my feelings of anxiety have diminished. This product has truly benefited our health, and I highly recommend it.
Read More
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8
High-dose vitamin D reduces anxiety
Effects of an 8-week high-dose vitamin D supplementation on fatigue and neuropsychiatric manifestations in post-COVID syndrome: A randomized controlled trial.
Directly assesses vitamin D's impact
We conducted a study to understand how high-dose vitamin D supplementation might impact anxiety levels, particularly in patients experiencing post-COVID symptoms. In our double-blind, randomized controlled trial, we enrolled 80 individuals dealing with fatigue or neuropsychiatric issues after COVID-19.
Participants were split into two groups: one received a weekly dose of 60,000 IU of vitamin D, while the other group received a placebo. Over eight weeks, we evaluated various outcomes, including anxiety levels using the Depression, Anxiety, and Stress Scale (DASS-21).
The results were encouraging for the vitamin D group. We observed significant improvements in anxiety levels, with a notable reduction reported by participants. However, other measures related to sleep quality, depression, cognitive function, and inflammatory markers did not show similar significant changes.
Importantly, we found that the vitamin D group reported no serious adverse effects, indicating that this supplementation is generally safe. These findings suggest that high-dose vitamin D may offer substantial benefits for anxiety relief in patients recovering from COVID-19, albeit with limited effects on other symptoms.
Participants were split into two groups: one received a weekly dose of 60,000 IU of vitamin D, while the other group received a placebo. Over eight weeks, we evaluated various outcomes, including anxiety levels using the Depression, Anxiety, and Stress Scale (DASS-21).
The results were encouraging for the vitamin D group. We observed significant improvements in anxiety levels, with a notable reduction reported by participants. However, other measures related to sleep quality, depression, cognitive function, and inflammatory markers did not show similar significant changes.
Importantly, we found that the vitamin D group reported no serious adverse effects, indicating that this supplementation is generally safe. These findings suggest that high-dose vitamin D may offer substantial benefits for anxiety relief in patients recovering from COVID-19, albeit with limited effects on other symptoms.
Read More
8
Vitamin D mitigates anxiety symptoms
Placenta-specific CYP11A1 overexpression lead to autism-like symptom in offspring with altered steroid hormone biosynthesis in the placenta-brain axis and rescued by vitamin D intervention.
Strong relevance to vitamin D effects
We explored the impact of changing levels of a specific enzyme, CYP11A1, in the placenta and how it might influence anxiety and social behavior in offspring. Using a unique mouse model, we found that higher levels of this enzyme are associated with behaviors similar to those seen in autism spectrum disorders (ASD), such as reduced social interaction and increased anxiety.
Interestingly, we observed that these anxiety-related behaviors improved significantly after administering vitamin D3. Behavioral tests, including open field and elevated plus maze assessments, showed that the mice exhibited less anxiety when given this supplement.
Additionally, our study highlighted that vitamin D3 could help correct some of the hormonal imbalances linked to CYP11A1 overexpression. Higher progesterone levels and increased inflammation were noted in the affected mice, and these issues seemed to reverse with vitamin D3 treatment.
This research underscores not only the potential role of vitamin D in managing anxiety but also suggests that examining CYP11A1 levels could be important for understanding and perhaps preventing some neurodevelopmental disorders. Overall, it appears vitamin D3 may serve as a useful tool in mitigating anxiety linked to hormonal changes during development.
Interestingly, we observed that these anxiety-related behaviors improved significantly after administering vitamin D3. Behavioral tests, including open field and elevated plus maze assessments, showed that the mice exhibited less anxiety when given this supplement.
Additionally, our study highlighted that vitamin D3 could help correct some of the hormonal imbalances linked to CYP11A1 overexpression. Higher progesterone levels and increased inflammation were noted in the affected mice, and these issues seemed to reverse with vitamin D3 treatment.
This research underscores not only the potential role of vitamin D in managing anxiety but also suggests that examining CYP11A1 levels could be important for understanding and perhaps preventing some neurodevelopmental disorders. Overall, it appears vitamin D3 may serve as a useful tool in mitigating anxiety linked to hormonal changes during development.
Read More
8
Link between Vitamin D and anxiety
Association of serum vitamin D with anxiety in US adults: a cross-sectional study.
High relevance for vitamin D research
We examined if there is a connection between vitamin D levels and anxiety among US adults, utilizing data from the National Health and Nutrition Examination Survey (NHANES) conducted between 2007 and 2012. The study included over 12,000 participants and employed sophisticated statistical methods to determine the relationship between serum vitamin D and anxiety.
Our analyses revealed that higher levels of serum vitamin D were associated with a lower risk of experiencing anxiety. Specifically, we found a significant inverse relationship; as vitamin D levels increased, the likelihood of anxiety decreased. This connection remained strong even after adjusting for various factors that could influence the results.
Furthermore, smooth curve fitting techniques confirmed a negative association between vitamin D and anxiety risk. Nonetheless, while these findings are promising, we emphasize the need for further prospective studies to validate these results and fully understand the implications of vitamin D on mental health.
Our analyses revealed that higher levels of serum vitamin D were associated with a lower risk of experiencing anxiety. Specifically, we found a significant inverse relationship; as vitamin D levels increased, the likelihood of anxiety decreased. This connection remained strong even after adjusting for various factors that could influence the results.
Furthermore, smooth curve fitting techniques confirmed a negative association between vitamin D and anxiety risk. Nonetheless, while these findings are promising, we emphasize the need for further prospective studies to validate these results and fully understand the implications of vitamin D on mental health.
Read More
8
Probiotics and vitamin D treatment
Probiotics plus vitamin D in irritable bowel syndrome: a prospective multicentric non-interventional study.
Limited insight on vitamin D
We evaluated the effectiveness of a treatment combining probiotics and vitamin D on patients suffering from irritable bowel syndrome, particularly focusing on those who experience anxiety. The study involved adult participants diagnosed with diarrhea-predominant IBS or mixed bowel movements, who took a daily sachet containing specific probiotic strains and vitamin D for 42 days.
At the end of the treatment period, we saw that a significant percentage of patients reported relief from their symptoms. Specifically, many in the study reported a marked decrease in the severity of their IBS symptoms, which was linked to improved quality of life and reductions in both anxiety and depression scores.
However, while vitamin D was part of the treatment regimen, it was used alongside probiotics, making it challenging to pinpoint the individual effect of vitamin D alone on anxiety. Still, the findings suggest that the combination might beneficially impact gut-related anxiety among IBS patients.
At the end of the treatment period, we saw that a significant percentage of patients reported relief from their symptoms. Specifically, many in the study reported a marked decrease in the severity of their IBS symptoms, which was linked to improved quality of life and reductions in both anxiety and depression scores.
However, while vitamin D was part of the treatment regimen, it was used alongside probiotics, making it challenging to pinpoint the individual effect of vitamin D alone on anxiety. Still, the findings suggest that the combination might beneficially impact gut-related anxiety among IBS patients.
Read More
7
Vitamin D may reduce anxiety
Associations Between Early-Pregnancy Vitamin D Status and Postpartum Depressive and Anxiety Symptoms.
Relevant study on vitamin D
We investigated whether vitamin D levels during pregnancy could predict anxiety symptoms in new mothers. In a large cohort study involving over 2,400 participants, we measured maternal serum vitamin D and C-reactive protein (CRP) levels around the 13-week mark of gestation. After giving birth, we checked in on the mothers three months later to assess their levels of depression and anxiety using standardized questionnaires.
Our findings suggest that insufficient vitamin D, particularly in women who did not take supplements, is linked to increased anxiety symptoms post-delivery. Specifically, a deficiency in vitamin D was associated with a noticeable rise in these symptoms, hinting that proper vitamin D levels might play a protective role. However, we found that CRP did not seem to mediate this relationship.
Overall, our research indicates that ensuring adequate vitamin D levels during pregnancy may be beneficial for reducing anxiety, especially for those not using supplements. Still, further clinical trials are needed to confirm whether vitamin D supplementation can actively mitigate postpartum affective disorders.
Our findings suggest that insufficient vitamin D, particularly in women who did not take supplements, is linked to increased anxiety symptoms post-delivery. Specifically, a deficiency in vitamin D was associated with a noticeable rise in these symptoms, hinting that proper vitamin D levels might play a protective role. However, we found that CRP did not seem to mediate this relationship.
Overall, our research indicates that ensuring adequate vitamin D levels during pregnancy may be beneficial for reducing anxiety, especially for those not using supplements. Still, further clinical trials are needed to confirm whether vitamin D supplementation can actively mitigate postpartum affective disorders.
Read More
User Reviews
USERS' SCORE
Excellent
Based on 1 Reviews
9.5
9.5
Reduced anxiety
I trust the Jarrow brand and was satisfied with their vitamin D, which I take with my family at breakfast. Coupled with K2, we have fallen ill less often, and my feelings of anxiety have diminished. This product has truly benefited our health, and I highly recommend it.
