Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.3
USERS' SCORE
Moderately Good
Based on 55 Reviews
7.8
Supplement Facts
Serving Size: 2 Vegetarian Capsules
Amount Per Serving
%DV
Thiamine (vitamin B1) (as thiamine HCl)
100 mg
8333%
Riboflavin (vitamin B2) (as riboflavin and riboflavin 5'-phosphate)
75 mg
5769%
Niacin (as niacinamide and niacin)
100 mg•
625%
Vitamin B6 (as pyridoxine HCl and pyridoxal 5' phosphate)
100 mg
5882%
Folate (as L-5-methyltetrahydrofolate calcium salt)
680 mcg○
170%
Vitamin B12 (as methylcobalamin)
300 mcg
12500%
Biotin
1000 mcg
3333%
Pantothenic acid (as D-calcium pantothenate)
500 mg
10000%
Calcium (as D-calcium pantothenate, dicalcium phosphate)
50 mg
4%
Inositol
100 mg
**
PABA (para-aminobenzoic acid)
50 mg
**
Top Medical Research Studies
8
We examined the impact of Niacin on anxiety and memory loss caused by aging in a rat study. Rats were grouped and treated with various doses of Niacin and D-galactose for 14 days, followed by behavioral tests to assess anxiety and memory.
Our results showed that Niacin significantly reduced anxiety-like symptoms and improved memory deficits. Additionally, it mitigated factors like oxidative stress and inflammation, enhancing brain health. Overall, Niacin's antioxidant and neuro-modulatory properties suggest it may be beneficial in addressing aging-related psychiatric issues.
Our results showed that Niacin significantly reduced anxiety-like symptoms and improved memory deficits. Additionally, it mitigated factors like oxidative stress and inflammation, enhancing brain health. Overall, Niacin's antioxidant and neuro-modulatory properties suggest it may be beneficial in addressing aging-related psychiatric issues.
Read More
We explored how vitamin B could help fight anxiety and depression linked to nicotine withdrawal in young male rats.
The study involved giving some rats nicotine before dividing them into different groups, where some were treated with vitamin B and others with bupropion—a common anxiety medication.
The results were promising, with vitamin B showing potential in reducing anxiety symptoms, comparable to bupropion. This opens the door for vitamin B as a possible new treatment option for various anxiety-related issues.
The study involved giving some rats nicotine before dividing them into different groups, where some were treated with vitamin B and others with bupropion—a common anxiety medication.
The results were promising, with vitamin B showing potential in reducing anxiety symptoms, comparable to bupropion. This opens the door for vitamin B as a possible new treatment option for various anxiety-related issues.
Read More
7
We investigated how Vitamin B can affect anxiety and depression in a rat model facing chronic stress. Seventy-two rats were divided into three groups: a control group, a stressed group, and a stressed group receiving Vitamin B injections.
The study measured behavioral changes and key neurotransmitter levels. Results showed that Vitamin B helped restore neurotransmitter levels and improved the rats' behavior. This suggests that Vitamin B could potentially play a role in alleviating anxiety and depressive symptoms by supporting brain health.
The study measured behavioral changes and key neurotransmitter levels. Results showed that Vitamin B helped restore neurotransmitter levels and improved the rats' behavior. This suggests that Vitamin B could potentially play a role in alleviating anxiety and depressive symptoms by supporting brain health.
Read More
Most Useful Reviews
7.5
Positive anxiety relief
526 people found this helpful
For a long time, I researched various vitamin B complex brands before choosing this one, and I have no regrets. These vitamins positively affect the nervous system, improving sleep, reducing anxiety, and helping to combat stress. They work best in combination as they enhance each other's effects. The dosages are high for quick replenishment, and the bright yellow urine is a normal bodily reaction. My whole family takes them, and we are very satisfied with the results. I highly recommend them.
Read More
7.5
Helps reduce anxiety
292 people found this helpful
This vitamin complex positively impacts all body systems, particularly the nervous system. It helps combat stress, alleviates tension, headaches, and anxiety, while improving attention and sleep. The dosages are well-balanced for enhanced effectiveness. I highly recommend it.
Read More
9
Effective for anxiety
254 people found this helpful
My husband and I took this supplement for two courses, and it has an excellent composition that absorbs well. It helps with post-covid symptoms, supports the nervous system, and reduces anxiety and muscle weakness. The high dosages are safe as they are water-soluble; any excess is excreted. It has greatly improved our overall well-being and sleep. I recommend it.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.3
- All Researches
8
We examined the impact of Niacin on anxiety and memory loss caused by aging in a rat study. Rats were grouped and treated with various doses of Niacin and D-galactose for 14 days, followed by behavioral tests to assess anxiety and memory.
Our results showed that Niacin significantly reduced anxiety-like symptoms and improved memory deficits. Additionally, it mitigated factors like oxidative stress and inflammation, enhancing brain health. Overall, Niacin's antioxidant and neuro-modulatory properties suggest it may be beneficial in addressing aging-related psychiatric issues.
Our results showed that Niacin significantly reduced anxiety-like symptoms and improved memory deficits. Additionally, it mitigated factors like oxidative stress and inflammation, enhancing brain health. Overall, Niacin's antioxidant and neuro-modulatory properties suggest it may be beneficial in addressing aging-related psychiatric issues.
Read More
We explored how vitamin B could help fight anxiety and depression linked to nicotine withdrawal in young male rats.
The study involved giving some rats nicotine before dividing them into different groups, where some were treated with vitamin B and others with bupropion—a common anxiety medication.
The results were promising, with vitamin B showing potential in reducing anxiety symptoms, comparable to bupropion. This opens the door for vitamin B as a possible new treatment option for various anxiety-related issues.
The study involved giving some rats nicotine before dividing them into different groups, where some were treated with vitamin B and others with bupropion—a common anxiety medication.
The results were promising, with vitamin B showing potential in reducing anxiety symptoms, comparable to bupropion. This opens the door for vitamin B as a possible new treatment option for various anxiety-related issues.
Read More
7
We investigated how Vitamin B can affect anxiety and depression in a rat model facing chronic stress. Seventy-two rats were divided into three groups: a control group, a stressed group, and a stressed group receiving Vitamin B injections.
The study measured behavioral changes and key neurotransmitter levels. Results showed that Vitamin B helped restore neurotransmitter levels and improved the rats' behavior. This suggests that Vitamin B could potentially play a role in alleviating anxiety and depressive symptoms by supporting brain health.
The study measured behavioral changes and key neurotransmitter levels. Results showed that Vitamin B helped restore neurotransmitter levels and improved the rats' behavior. This suggests that Vitamin B could potentially play a role in alleviating anxiety and depressive symptoms by supporting brain health.
Read More
7
Vitamin B aids anxiety recovery
We explored the effects of vitamin B supplementation on anxiety and cognitive function in male Swiss albino mice following traumatic brain injury (TBI). Our research found that vitamin B appears to improve neurological impairments, enhance memory, and reduce anxiety-like behaviors.
Additionally, we saw a reduction in oxidative stress markers, indicating better neuronal health. This suggests that vitamin B not only helps with anxiety but also plays a role in recovery from cognitive dysfunctions associated with TBI.
Additionally, we saw a reduction in oxidative stress markers, indicating better neuronal health. This suggests that vitamin B not only helps with anxiety but also plays a role in recovery from cognitive dysfunctions associated with TBI.
Read More
We explored the effectiveness of vitamin B complex in treating anxiety among patients with Post-COVID-19 syndrome (PC19S) through the PreVitaCOV trial. This study involved 240 participants who were given either prednisolone, vitamin B1, B6, and B12, a combination of these treatments, or a placebo. While the trial showed high feasibility and safety, it ultimately did not demonstrate significant benefits in symptom change over placebo in anxiety or other evaluated symptoms.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 55 Reviews
7.8
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Positive anxiety relief
526 people found this helpful
For a long time, I researched various vitamin B complex brands before choosing this one, and I have no regrets. These vitamins positively affect the nervous system, improving sleep, reducing anxiety, and helping to combat stress. They work best in combination as they enhance each other's effects. The dosages are high for quick replenishment, and the bright yellow urine is a normal bodily reaction. My whole family takes them, and we are very satisfied with the results. I highly recommend them.
Read More
7.5
Helps reduce anxiety
292 people found this helpful
This vitamin complex positively impacts all body systems, particularly the nervous system. It helps combat stress, alleviates tension, headaches, and anxiety, while improving attention and sleep. The dosages are well-balanced for enhanced effectiveness. I highly recommend it.
Read More
9
Effective for anxiety
254 people found this helpful
My husband and I took this supplement for two courses, and it has an excellent composition that absorbs well. It helps with post-covid symptoms, supports the nervous system, and reduces anxiety and muscle weakness. The high dosages are safe as they are water-soluble; any excess is excreted. It has greatly improved our overall well-being and sleep. I recommend it.
Read More
7.5
Boosts energy, reduces anxiety
212 people found this helpful
If you lack energy, especially after covid, I recommend this supplement. It contains a fantastic mix of B vitamins and other beneficial ingredients. You only need one capsule daily, providing two months' worth. B vitamins are water-soluble, so any excess will leave the body through urine, causing the bright yellow colour. It boosts vitality and helps regulate sleep while reducing anxiety.
Read More
7.5
Alleviates anxiety symptoms
203 people found this helpful
This perfectly balanced vitamin complex benefits all body systems, especially helping to address deficiencies. It positively influences the nervous system by enhancing sleep, reducing anxiety, and alleviating tension. The combination of B vitamins is more effective than taking them individually. The dosages are substantial, and I combine these vitamins with magnesium for enhanced results. I take them once every six months and find them effective for my needs.
Read More
Frequently Asked Questions
9
Effective for anxiety
7 people found this helpful
This B complex has been a lifesaver during a very depressed period. After consulting an endocrinologist who recognised my anxiety, I began taking vitamin B6 at a high dosage along with this complex. Within a few days, I felt calmer. I now take it for maintenance. The quality is evident, the packaging is appealing, and the taste is fine. The effect is what matters most to me. Just love it❤️
9
Reduces stress
2 people found this helpful
I began taking these vitamins during a stressful period. After two weeks, I experienced significant improvements; my anxiety and emotional upheaval faded. I am completely satisfied and plan to take this supplement periodically throughout the year.
0
Extreme anxiety reactions
Be cautious with this vitamin complex; it contains methylated B vitamins that some individuals, like myself, react poorly to. After a few days, I experienced severe anxiety, insomnia, and appetite loss. I should have read the label more carefully!
9
Reduces anxiety significantly
67 people found this helpful
Since taking this activated B vitamin complex, I've noticed a substantial difference in my anxiety levels, especially after my car accident. I take three capsules daily, which have alleviated nerve pain and significantly improved my mental and physical well-being. After testing, I now take the capsules more cautiously, focusing on their beneficial impact.
7.5
Helps reduce anxiety
292 people found this helpful
This vitamin complex positively impacts all body systems, particularly the nervous system. It helps combat stress, alleviates tension, headaches, and anxiety, while improving attention and sleep. The dosages are well-balanced for enhanced effectiveness. I highly recommend it.
0
Be cautious with dosage
BE AWARE!! The product is high quality but managing methylation should be supervised. It contains methyl forms of B12 and folate, which can lead to overmethylation, worsening anxiety and other mental conditions. With proper supervision, this is a powerful product despite its large pill size.
7.5
Alleviates anxiety symptoms
203 people found this helpful
This perfectly balanced vitamin complex benefits all body systems, especially helping to address deficiencies. It positively influences the nervous system by enhancing sleep, reducing anxiety, and alleviating tension. The combination of B vitamins is more effective than taking them individually. The dosages are substantial, and I combine these vitamins with magnesium for enhanced results. I take them once every six months and find them effective for my needs.
9
Restores vitamin levels
3 people found this helpful
This complex effectively addresses B vitamin shortfalls, enhancing our nervous system. It improves sleep, alleviates anxiety, and combats stress. B vitamins are best consumed together to enhance absorption. The bioavailability of these vitamins ensures quick restoration of your vitamin levels, significantly improving health.
7.5
Boosts energy, reduces anxiety
212 people found this helpful
If you lack energy, especially after covid, I recommend this supplement. It contains a fantastic mix of B vitamins and other beneficial ingredients. You only need one capsule daily, providing two months' worth. B vitamins are water-soluble, so any excess will leave the body through urine, causing the bright yellow colour. It boosts vitality and helps regulate sleep while reducing anxiety.
7
We investigated how Vitamin B can affect anxiety and depression in a rat model facing chronic stress. Seventy-two rats were divided into three groups: a control group, a stressed group, and a stressed group receiving Vitamin B injections.
The study measured behavioral changes and key neurotransmitter levels. Results showed that Vitamin B helped restore neurotransmitter levels and improved the rats' behavior. This suggests that Vitamin B could potentially play a role in alleviating anxiety and depressive symptoms by supporting brain health.
The study measured behavioral changes and key neurotransmitter levels. Results showed that Vitamin B helped restore neurotransmitter levels and improved the rats' behavior. This suggests that Vitamin B could potentially play a role in alleviating anxiety and depressive symptoms by supporting brain health.
7
Vitamin B aids anxiety recovery
We explored the effects of vitamin B supplementation on anxiety and cognitive function in male Swiss albino mice following traumatic brain injury (TBI). Our research found that vitamin B appears to improve neurological impairments, enhance memory, and reduce anxiety-like behaviors.
Additionally, we saw a reduction in oxidative stress markers, indicating better neuronal health. This suggests that vitamin B not only helps with anxiety but also plays a role in recovery from cognitive dysfunctions associated with TBI.
Additionally, we saw a reduction in oxidative stress markers, indicating better neuronal health. This suggests that vitamin B not only helps with anxiety but also plays a role in recovery from cognitive dysfunctions associated with TBI.
We explored the effectiveness of vitamin B complex in treating anxiety among patients with Post-COVID-19 syndrome (PC19S) through the PreVitaCOV trial. This study involved 240 participants who were given either prednisolone, vitamin B1, B6, and B12, a combination of these treatments, or a placebo. While the trial showed high feasibility and safety, it ultimately did not demonstrate significant benefits in symptom change over placebo in anxiety or other evaluated symptoms.
References
- Chen J, Liu J, Zhang P, Zhang S. [Effects of Vitamin B on Behaviors, Brain Monoamine Neurotransmitters, and Brain-Derived Neurotrophic Factor in Depressive Rats]. Sichuan Da Xue Xue Bao Yi Xue Ban. 2025;56:206. 10.12182/20250160608
- Samad N, Hameed A, Manzoor N, Shoukat S, Irfan A, et al. Antioxidant and neuro-modulatory effects of niacin prevent D-galactose-induced behavioral deficits and memory impairment. Exp Gerontol. 2024;198:112624. 10.1016/j.exger.2024.112624
- Yadav P, Nasir F, Sivanandam TM. Neuroprotective effect of vitamin B supplementation on cognitive functions and neuronal morphology at different time intervals after traumatic brain injury in male Swiss albino mice. Neurochem Int. 2024;180:105869. 10.1016/j.neuint.2024.105869
- Tengelmann C, Joos S, Kaußner Y, Malzahn U, Lunden L, et al. Feasibility, safety and effectiveness of prednisolone and vitamin B1, B6, and B12 in patients with post-COVID-19-syndrome (PreVitaCOV) - protocol of a randomised, double-blind, placebo-controlled multicentre trial in primary care (phase IIIb). BMC Infect Dis. 2024;24:56. 10.1186/s12879-023-08925-2
- Pahlavani H, Masoudi M, Khoshroo N, Kakhki S, Mahdi Rezavanimehr M, et al. Vitamin B reversed anxiety and depression induced by adolescent nicotine withdrawal through alteration the inflammatory, oxidative and serotoninergic profiles in male rats. Biochem Pharmacol. 2023;217:115832. 10.1016/j.bcp.2023.115832
- Kakhki S, Goodarzi M, Abbaszade-Cheragheali A, Rajabi M, Masoumipour AH, et al. Folic acid supplementation improved cognitive deficits associated with lithium administration during pregnancy in rat offspring. Int J Dev Neurosci. 2023;83:615. 10.1002/jdn.10289
- Shemirani F, Titcomb TJ, Saxby SM, Eyck PT, Rubenstein LM, et al. Association of serum homocysteine, folate, and vitamin B and mood following the Swank and Wahls elimination dietary interventions in relapsing-remitting multiple sclerosis: Secondary analysis of the WAVES trial. Mult Scler Relat Disord. 2023;75:104743. 10.1016/j.msard.2023.104743
