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Supplement Facts
Serving Size: 1 Vegetarian Capsule
Amount Per Serving
%DV
Magnesium [as magnesium oxide, citrate, succinate)
500 mg
119%
The product is found useful for the following medical conditions
Depression details
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.3
USERS' SCORE
Excellent
Based on 18 Reviews
9
9
Magnesium intake reduces depression risk
Dietary Magnesium Intake in Relation to Depression in Adults: A GRADE-Assessed Systematic Review and Dose-Response Meta-analysis of Epidemiologic Studies.
Most Relevant Research
We conducted a systematic review and meta-analysis exploring how dietary magnesium (Mg) intake connects with depression among adults. By reviewing data from over 63,000 individuals, we found that those with the highest magnesium intake had a 34% lower chance of experiencing depression compared to those with the lowest intake.
Furthermore, our analysis indicated that every increase of 100 mg per day in magnesium intake was linked to a 7% reduced risk of depression. These findings suggest that increasing dietary magnesium could play a valuable role in lowering depression risk.
Furthermore, our analysis indicated that every increase of 100 mg per day in magnesium intake was linked to a 7% reduced risk of depression. These findings suggest that increasing dietary magnesium could play a valuable role in lowering depression risk.
9.5
Improved well-being
Most Useful Review
I had been experiencing constant sleepiness, headaches, irritability, and depression before starting magnesium. Using Magnesium Caps has helped me assimilate essential vitamins and minerals, thin my blood, and synthesise the hormone of joy. It effectively alleviated insomnia and my migraines, apathy and depression have vanished. I now feel refreshed after six hours of sleep and my mental clarity has improved significantly. I highly recommend it, especially when taken before bedtime!
Knee Pain details
SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8
USERS' SCORE
Excellent
Based on 15 Reviews
9
9
Magnesium sulfate alleviates postoperative pain
Effects of magnesium sulfate on periarticular infiltration analgesia in total knee arthroplasty: a prospective, double-blind, randomized controlled trial.
Most Relevant Research
We explored the impact of magnesium sulfate on managing pain following total knee arthroplasty. In a randomized, double-blind trial with 90 patients, half received a blend of analgesics that included magnesium sulfate, while the other half did not.
Following surgery, the results showed that magnesium sulfate helped prolong pain relief and reduced the need for opioids. Patients receiving it experienced less postoperative pain and moved towards recovery more effectively.
Overall, adding magnesium sulfate appears beneficial for postoperative knee pain management.
Following surgery, the results showed that magnesium sulfate helped prolong pain relief and reduced the need for opioids. Patients receiving it experienced less postoperative pain and moved towards recovery more effectively.
Overall, adding magnesium sulfate appears beneficial for postoperative knee pain management.
9.5
Alleviated knee pain
Most Useful Review
I started taking magnesium to combat my back pain and was pleasantly surprised to find my knee pain improved as well. It's remarkable how quickly the pain alleviated, though skipping doses does bring back the discomfort!
Headache details
SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7.4
USERS' SCORE
Good
Based on 63 Reviews
8.9
9
We explored the impact of magnesium on migraine headaches, focusing on its potential benefits based on various studies. Magnesium deficiency is quite common and can arise from different factors, such as not consuming enough through diet or losing more through bodily systems.
A wealth of research, including case reports and controlled trials, suggests that magnesium supplementation can effectively alleviate migraines, both in the short term and long term. The proposed reasons for this effectiveness range from magnesium's role in preventing spreading cortical depression to its ability to manage oxidative stress and inflammation.
This evidence leads us to consider magnesium not just as a dietary supplement but as an important player in migraine management. Understanding these links helps us contemplate magnesium’s role in prevention and treatment, promising a potential path for those who suffer from this debilitating condition.
A wealth of research, including case reports and controlled trials, suggests that magnesium supplementation can effectively alleviate migraines, both in the short term and long term. The proposed reasons for this effectiveness range from magnesium's role in preventing spreading cortical depression to its ability to manage oxidative stress and inflammation.
This evidence leads us to consider magnesium not just as a dietary supplement but as an important player in migraine management. Understanding these links helps us contemplate magnesium’s role in prevention and treatment, promising a potential path for those who suffer from this debilitating condition.
9.5
Stops severe headaches
Most Useful Review
Fantastic Magnesium supplement. I opted for this product after extensive research on magnesium supplements online. My previous brand rated poorly on Labdoor.com, but this supplement emerged as their top-ranking magnesium supplement. I have trusted Labdoor for a long time, and this product proved to be excellent; I noticed improvements within a week. It alleviated issues like difficulty sleeping, muscle cramps, slightly elevated blood pressure, and importantly, my severe headaches from occipital neuralgia. Ever since I started taking magnesium several years ago, I haven't experienced a bad headache.
Leg Cramps details
SCIENTIFIC SCORE
Likely Ineffective
Based on 17 Researches
4.8
USERS' SCORE
Good
Based on 187 Reviews
8.9
9
Magnesium oxide treats leg cramps
A randomized, double-blind, placebo-controlled, multicenter study assessing the efficacy of magnesium oxide monohydrate in the treatment of nocturnal leg cramps.
Most Relevant Research
We conducted a study to evaluate how effective magnesium oxide monohydrate (MOMH) is in treating nocturnal leg cramps (NLC). This was a randomized, double-blind, placebo-controlled trial involving multiple centers in Ukraine, where participants took either MOMH or a placebo nightly for 60 days.
Our focus was on measuring the frequency and duration of cramps, the pain they caused, and how they affected sleep quality and overall life satisfaction. We used thorough statistical methods to compare the results between the two groups.
The findings indicated that MOMH is both effective and safe for individuals dealing with NLC. Participants reported improvements in their symptoms, demonstrating that this magnesium supplement can play a helpful role in managing nocturnal leg cramps.
Our focus was on measuring the frequency and duration of cramps, the pain they caused, and how they affected sleep quality and overall life satisfaction. We used thorough statistical methods to compare the results between the two groups.
The findings indicated that MOMH is both effective and safe for individuals dealing with NLC. Participants reported improvements in their symptoms, demonstrating that this magnesium supplement can play a helpful role in managing nocturnal leg cramps.
9.5
Eliminated leg cramps
Most Useful Review
I liked Now Foods magnesium 500 mg. The capsules come in good packaging, with 100 capsules at an acceptable price. Taking one capsule daily eliminated my irritability, helped normalise my sleep, and stopped my leg cramps. This effective supplement improved my mood and condition without side effects.
Anxiety details
SCIENTIFIC SCORE
Questionable
Based on 12 Researches
6.9
USERS' SCORE
Good
Based on 49 Reviews
8.8
8
Magnesium treats anxiety in MS
Nanoparticulate MgH ameliorates anxiety/depression-like behaviors in a mouse model of multiple sclerosis by regulating microglial polarization and oxidative stress.
Most Relevant Research
We aimed to understand the impact of nanoparticulate magnesium hydride (MgH) on anxiety and depression associated with multiple sclerosis (MS). Our exploration involved studying how MgH affects mood disorders in a model we designed, specifically using experimental autoimmune encephalomyelitis (EAE) mice.
We discovered that MgH treatment significantly alleviated anxiety and depression-like behaviors in these mice. Not only did MgH help improve their mood, but it also reduced overall disease severity and inflammatory damage within the central nervous system.
Importantly, our findings suggest that MgH could be working by promoting healthier microglial activity. It appears to encourage the beneficial M2 polarization while inhibiting the harmful M1 polarization, alongside reducing oxidative stress. This mechanism offers a glimpse into how magnesium might truly enhance well-being for those dealing with MS-related psychiatric issues.
In summary, our research indicates that nanoparticulate MgH holds promise as a non-toxic and effective treatment option for anxiety and depression in people suffering from MS, showcasing a potential breakthrough in managing these debilitating conditions.
We discovered that MgH treatment significantly alleviated anxiety and depression-like behaviors in these mice. Not only did MgH help improve their mood, but it also reduced overall disease severity and inflammatory damage within the central nervous system.
Importantly, our findings suggest that MgH could be working by promoting healthier microglial activity. It appears to encourage the beneficial M2 polarization while inhibiting the harmful M1 polarization, alongside reducing oxidative stress. This mechanism offers a glimpse into how magnesium might truly enhance well-being for those dealing with MS-related psychiatric issues.
In summary, our research indicates that nanoparticulate MgH holds promise as a non-toxic and effective treatment option for anxiety and depression in people suffering from MS, showcasing a potential breakthrough in managing these debilitating conditions.
9.5
Supports anxiety relief
Most Useful Review
My favourite magnesium supplement has a high dosage of 500 mg per capsule. It effectively supports my nervous system, combats anxiety, helps with muscle cramps, and stabilises sleep. I take one capsule each evening a few hours before bed. The packaging lasts me 3.5 months, and I’m very satisfied with the quality and dosage. There are three forms of magnesium in the composition, ensuring rapid absorption in my body.
Insomnia details
SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7.4
USERS' SCORE
Good
Based on 68 Reviews
8.8
9
Magnesium improves elderly insomnia
The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial.
Most Relevant Research
We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
9.5
Fights insomnia effectively
Most Useful Review
Using Magnesium Caps has markedly improved my daily sleepiness, irritability, and headaches. I found that it reduces insomnia, and I no longer experience migraines or apathy. I feel refreshed after a good night’s sleep. I highly recommend it, especially if taken before bedtime!
Migraine details
SCIENTIFIC SCORE
Possibly Effective
Based on 17 Researches
7.4
USERS' SCORE
Good
Based on 26 Reviews
8.8
9
We explored how magnesium supplementation can help alleviate migraines, a condition that affects countless individuals and can be incredibly disabling. Research has shown a strong link between magnesium deficiency and various factors that contribute to migraines, such as neurological changes and inflammation.
Studies, including randomized controlled trials, indicate that magnesium can reduce the frequency and severity of migraine attacks, both in the short term and as a preventative measure. This effectiveness is thought to stem from magnesium's ability to influence nerve function and reduce stress responses in the body.
We've examined the accumulating evidence from case studies and clinical trials, and it clearly points to magnesium being a valuable option for those suffering from migraines. By addressing magnesium deficiency, we may offer a new avenue for relief and improved management of this challenging condition.
Studies, including randomized controlled trials, indicate that magnesium can reduce the frequency and severity of migraine attacks, both in the short term and as a preventative measure. This effectiveness is thought to stem from magnesium's ability to influence nerve function and reduce stress responses in the body.
We've examined the accumulating evidence from case studies and clinical trials, and it clearly points to magnesium being a valuable option for those suffering from migraines. By addressing magnesium deficiency, we may offer a new avenue for relief and improved management of this challenging condition.
9.5
Reduced migraines
Most Useful Review
Using Magnesium Caps has been transformative! Before, I struggled with constant sleepiness, headaches, irritability, and nervousness. This supplement aids in the absorption of vitamins and minerals, effectively thinning the blood and reducing my migraines. It also helped me overcome insomnia and depression. I now wake refreshed after just six hours of sleep. Highly recommended!
Back Pain details
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.5
USERS' SCORE
Good
Based on 36 Reviews
8.7
9.5
Magnesium reduces postoperative back pain
Effect of perioperative intravenous magnesium sulfate on postoperative pain after iliac venous stenting.
Most Relevant Research
We explored the effectiveness of magnesium sulfate (MS) in relieving low back pain (LBP) for patients who underwent iliac venous stenting. This study involved 97 patients, divided into two groups: one received MS infusion during their surgery, while the other did not.
Patients who received MS experienced significantly lower pain levels at all follow-up intervals. We found that, at 24 hours after surgery, those in the magnesium group consumed much less tramadol—a common pain medication—compared to the control group. Additionally, the need for extra pain relief was lower among those who received magnesium.
Importantly, the side effects like nausea and vomiting were similar in both groups, indicating that magnesium can be a safe option for pain management after this type of surgery. Overall, the findings suggest that magnesium sulfate not only alleviates pain but also reduces reliance on opioids, making it a valuable treatment for postoperative care.
Patients who received MS experienced significantly lower pain levels at all follow-up intervals. We found that, at 24 hours after surgery, those in the magnesium group consumed much less tramadol—a common pain medication—compared to the control group. Additionally, the need for extra pain relief was lower among those who received magnesium.
Importantly, the side effects like nausea and vomiting were similar in both groups, indicating that magnesium can be a safe option for pain management after this type of surgery. Overall, the findings suggest that magnesium sulfate not only alleviates pain but also reduces reliance on opioids, making it a valuable treatment for postoperative care.
9.5
Alleviated back pain
Most Useful Review
I started taking magnesium for my back pain. After a few days, I noticed a significant reduction in pain, and it almost disappeared when I continued taking it. However, the pain returns if I miss a dose!
Cardiovascular Disease details
SCIENTIFIC SCORE
Questionable
Based on 12 Researches
6.8
USERS' SCORE
Good
Based on 38 Reviews
8.7
8
Magnesium's impact on heart health
The Role of Dietary Magnesium in Cardiovascular Disease.
Most Relevant Research
We examined the connection between dietary magnesium and cardiovascular disease, focusing on how magnesium intake or serum levels relate to heart health. Over the last couple of decades, numerous studies have shown that low magnesium levels are associated with several heart-related issues, including high blood pressure, heart attacks, and even heart failure.
Our insights reveal that even mild or moderate magnesium deficiencies can trigger physiological and metabolic changes that may heighten cardiovascular risks. When magnesium levels are insufficient, we see a rise in inflammation, oxidative stress, and issues with how fats are processed in the body, which can lead to serious heart problems.
Furthermore, we noted that many individuals often consume less magnesium than what is recommended, particularly those who do not regularly eat whole grains, legumes, or green vegetables. This widespread lack of magnesium is concerning, as it could be a significant factor influencing heart disease in the general population.
Our insights reveal that even mild or moderate magnesium deficiencies can trigger physiological and metabolic changes that may heighten cardiovascular risks. When magnesium levels are insufficient, we see a rise in inflammation, oxidative stress, and issues with how fats are processed in the body, which can lead to serious heart problems.
Furthermore, we noted that many individuals often consume less magnesium than what is recommended, particularly those who do not regularly eat whole grains, legumes, or green vegetables. This widespread lack of magnesium is concerning, as it could be a significant factor influencing heart disease in the general population.
8.8
Eases cardiovascular issues
Most Useful Review
I took magnesium while recovering from COVID-19 to address deficiency, taking 1000 mg daily. I enjoy this product without side effects. It improves cardiovascular function and my nervous system, so I recommend drinking it in cycles for optimal benefits.
Heart Disease details
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.4
USERS' SCORE
Good
Based on 48 Reviews
8.7
7
Magnesium supplements lower heart failure risk
Nonprescription Magnesium Supplement Use and Risk of Heart Failure in Patients With Diabetes: A Target Trial Emulation.
Most Relevant Research
We examined how magnesium supplements might influence heart failure and serious heart-related issues in diabetic patients.
In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.
Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.
In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.
Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.
9.5
Aids heart recovery
Most Useful Review
Quality magnesium for recovery after intense workouts. It has notably improved my heart health, especially post-leg workouts. I recommend taking it with food, ideally in the evening, and consider adding zinc and BCAA for optimal results.
Hypothyroidism details
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.7
USERS' SCORE
Good
Based on 5 Reviews
8.7
4
Magnesium shows promise in thyroid recovery
Proof of concept of the WOMED model of benign thyroid disease: Restitution of thyroid morphology after correction of physical and psychological stressors and magnesium supplementation.
Most Relevant Research
We set out to investigate how magnesium, along with selenium and coenzyme Q10, could influence hypothyroidism in patients with benign thyroid diseases. Our approach included a small group of eight patients—five with hyperthyroidism and three with hypothyroidism—who received additional treatment aimed at addressing both their thyroid condition and related physical and psychological stresses.
Over a period of 2 to 4 years, we observed some significant changes. Initially, we focused on correcting musculoskeletal issues, followed by addressing stress. As a result, we noted that thyroid morphology normalized in many cases, which was confirmed through ultrasound examinations. Interestingly, we also saw a reduction in thyroid antibody levels for most patients.
However, we must be transparent about our findings. While magnesium and the other supplements showed promise, there were two cases of chronic thyroiditis that did not respond positively to treatment, possibly due to long-standing fibrosis. This indicates that while magnesium may play a role in thyroid health, its effectiveness can vary significantly based on individual circumstances and the duration of the thyroid condition.
Over a period of 2 to 4 years, we observed some significant changes. Initially, we focused on correcting musculoskeletal issues, followed by addressing stress. As a result, we noted that thyroid morphology normalized in many cases, which was confirmed through ultrasound examinations. Interestingly, we also saw a reduction in thyroid antibody levels for most patients.
However, we must be transparent about our findings. While magnesium and the other supplements showed promise, there were two cases of chronic thyroiditis that did not respond positively to treatment, possibly due to long-standing fibrosis. This indicates that while magnesium may play a role in thyroid health, its effectiveness can vary significantly based on individual circumstances and the duration of the thyroid condition.
9.5
Effective supplement
Most Useful Review
After being diagnosed with hypothyroidism and trying hormonal therapy with no improvement, I decided to try magnesium. I've been taking it for less than a week, and I already feel better—no more freezing limbs or constipation. This supplement genuinely works!
Vertigo details
SCIENTIFIC SCORE
Likely Very Effective
Based on 3 Researches
9.3
USERS' SCORE
Good
Based on 2 Reviews
8.7
9.5
Effective magnesium treatment for vertigo
Successful treatment of a child with definite Meniere's disease with the migraine regimen.
Most Relevant Research
We explored the relationship between magnesium treatment and vertigo in a remarkable case involving a 5-year-old girl with Meniere's disease (MD). This young patient had been suffering from six months of left-sided hearing loss, followed by troubling daily episodes of vertigo, persistent headaches, and vomiting. She met the established criteria for definite MD, which made her situation particularly concerning for both her and her family.
After initiating a 6-week diet and lifestyle regimen aimed at migraine management, which included magnesium, we observed promising results. The patient reported being symptom-free and showed a significant improvement in her hearing, reaching near-normal levels. This outcome has led us to believe that the vertigo and other symptoms associated with MD may actually be linked to a vestibular migraine phenomenon, suggesting that magnesium and lifestyle changes could play a key role in alleviating these symptoms in pediatric patients.
Our findings suggest that children with MD might benefit from these migraine-oriented lifestyle modifications, highlighting the need for some researchers and caregivers to consider alternative approaches for treating children's vestibular symptoms.
After initiating a 6-week diet and lifestyle regimen aimed at migraine management, which included magnesium, we observed promising results. The patient reported being symptom-free and showed a significant improvement in her hearing, reaching near-normal levels. This outcome has led us to believe that the vertigo and other symptoms associated with MD may actually be linked to a vestibular migraine phenomenon, suggesting that magnesium and lifestyle changes could play a key role in alleviating these symptoms in pediatric patients.
Our findings suggest that children with MD might benefit from these migraine-oriented lifestyle modifications, highlighting the need for some researchers and caregivers to consider alternative approaches for treating children's vestibular symptoms.
10
Significant relief
Most Useful Review
This has been a lifesaver for me. Since starting this product, my vertigo has significantly improved, and the issues related to my Ménière’s Disease, such as balance problems and ear ringing, have disappeared. I intend to continue, as it has helped me greatly.
Blurred Vision details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
8.8
Enhanced vision
Most Useful Review
My condition is improving daily. I’ve noticed a significant enhancement in my skin, hair, and nails, along with better hearing and vision. I am truly grateful for such excellent products and am very pleased with the results.
Bone Pain details
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7
USERS' SCORE
Good
Based on 75 Reviews
8.6
7
CMT shows potential for pain relief
The efficacy of choline magnesium trisalicylate (CMT) in the management of metastatic bone pain: a pilot study.
Most Relevant Research
We investigated how choline magnesium trisalicylate (CMT) helps alleviate bone pain in patients with metastatic cancer. In a carefully designed study involving 26 participants, we compared CMT against a placebo in a crossover format, measuring pain relief at multiple intervals after dosing.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
8.8
No bone pain
Most Useful Review
Working magnesium is excellent. I take one pill in the evening after discovering my magnesium levels were nearly zero. Despite being an emotional person, I've noticed no muscle pain or nerve issues during its use—it's clearly effective!
Chronic Cough details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
9.5
Effective supplement
Most Useful Review
This magnesium supplement is effective for my chronic condition following a kidney injury, resulting in a magnesium deficiency. It's one of the few formulations that significantly impacts my lab reports. I recommend taking it in the evening as it helps relax my skeletal muscles and aids sleep.
Chronic Fatigue Syndrome details
SCIENTIFIC SCORE
Questionable
Based on 5 Researches
6.6
USERS' SCORE
Good
Based on 57 Reviews
8.6
8
Magnesium potentially benefits CFS patients
Red blood cell magnesium and chronic fatigue syndrome.
Most Relevant Research
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.
In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.
In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.
In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
9.5
Improved sleep quality
Most Useful Review
After taking magnesium, I found I became much calmer, my sleep improved, and my legs stopped hurting. Magnesium is crucial for our bodies and is recommended for pregnant women. I take 2 capsules after meals or 30-40 minutes before bedtime. Since using this product, I sleep well, feel less fatigued, and manage my duties as a mother more effectively. I highly recommend it; the quality matches the price, and I appreciate the capsule size.
Common Cold details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 4 Reviews
8.6
8.8
Effective for colds
Most Useful Review
This magnesium is excellent. A cardiologist found an abnormality in my heart, which could be linked to my mother’s vitamin D deficiency during pregnancy. I experienced tachycardia and cramps in my calves. Within a week of taking this supplement, I noticed significant improvement. I prioritised chelated forms due to their higher bioavailability compared to inorganic compounds. This product combines magnesium oxide, citrate, succinate, and lysylglycinate chelate.
Kidney Stones details
SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7.3
USERS' SCORE
Good
Based on 9 Reviews
8.5
9
Magnesium reduces kidney stone risk
Effect of magnesium oxide or citrate supplements on metabolic risk factors in kidney stone formers with idiopathic hyperoxaluria: a randomized clinical trial.
Most Relevant Research
We conducted a randomized, double-blind, placebo-controlled clinical trial to explore how magnesium treatments influence kidney stones, specifically for those with high levels of oxalate in their urine. Our study involved 90 participants with a history of calcium kidney stones, all of whom were experiencing idiopathic hyperoxaluria. They were divided into three groups receiving either magnesium oxide (MgO), magnesium citrate (MgCit), or a placebo for eight weeks, while their diets were monitored to keep nutritional intake consistent.
After the treatment period, we observed promising results. Both MgO and MgCit effectively reduced the excretion of oxalate in urine, which is a key factor in kidney stone formation. The Group taking magnesium citrate showed even more significant reductions in both oxalate levels and the calcium oxalate supersaturation index, which measures the concentration of stone-forming minerals in urine. This was notably true for participants with normal magnesium levels.
Overall, we found that magnesium supplements might play a beneficial role in decreasing critical risk factors for kidney stones, especially for those using magnesium citrate. It's encouraging to see that this may offer a practical option for those struggling with recurrent stones due to high oxalate excretion.
After the treatment period, we observed promising results. Both MgO and MgCit effectively reduced the excretion of oxalate in urine, which is a key factor in kidney stone formation. The Group taking magnesium citrate showed even more significant reductions in both oxalate levels and the calcium oxalate supersaturation index, which measures the concentration of stone-forming minerals in urine. This was notably true for participants with normal magnesium levels.
Overall, we found that magnesium supplements might play a beneficial role in decreasing critical risk factors for kidney stones, especially for those using magnesium citrate. It's encouraging to see that this may offer a practical option for those struggling with recurrent stones due to high oxalate excretion.
9.5
Eases kidney stones
Most Useful Review
This magnesium supplement is effective for my magnesium deficiency due to a chronic kidney condition. I have noticed positive changes in my blood reports. I recommend taking it in the evening, as it relaxes muscles and aids sleep.
Tinnitus details
SCIENTIFIC SCORE
Moderately Effective
Based on 6 Researches
8
USERS' SCORE
Good
Based on 3 Reviews
8.5
8
Magnesium's role in tinnitus explored
Relationship between serum magnesium level and subjective tinnitus.
Most Relevant Research
We explored the connection between serum magnesium levels and the occurrence of severe bilateral subjective tinnitus. This study involved 76 patients suffering from this distressing condition and compared them to 86 healthy participants.
By measuring and analyzing the magnesium levels in both groups, we observed that those with tinnitus had significantly lower magnesium concentrations—1.8 mg/dL compared to 2.3 mg/dL in the control group. This difference suggests that magnesium may play a role in the body’s response to tinnitus.
Our findings indicate that magnesium could be an important factor in understanding the pathophysiology of subjective tinnitus. While this doesn’t confirm that magnesium treatment will alleviate tinnitus symptoms, it certainly opens up avenues for further research in this area.
By measuring and analyzing the magnesium levels in both groups, we observed that those with tinnitus had significantly lower magnesium concentrations—1.8 mg/dL compared to 2.3 mg/dL in the control group. This difference suggests that magnesium may play a role in the body’s response to tinnitus.
Our findings indicate that magnesium could be an important factor in understanding the pathophysiology of subjective tinnitus. While this doesn’t confirm that magnesium treatment will alleviate tinnitus symptoms, it certainly opens up avenues for further research in this area.
9.5
Resolved dizziness
Most Useful Review
I bought magnesium as I was feeling dizzy and dealing with tinnitus, and it worked effectively.
Stroke details
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.5
USERS' SCORE
Good
Based on 2 Reviews
8.4
9
Magnesium shows neuroprotective promise
Neuroprotection on ischemic brain injury by Mg/H released from endovascular Mg implant.
Most Relevant Research
We embarked on an intriguing exploration of how magnesium might help during cerebral ischemia, particularly after an acute stroke. The study set out to determine the potential benefits of a biodegradable neuroprotective stent that releases magnesium into the bloodstream, targeting areas impacted by reperfusion injury.
To do this, we first looked at how pure magnesium affected neuron cells that had undergone oxygen-glucose deprivation and reoxygenation. Encouragingly, we found that the magnesium could indeed protect these cells from injury.
Building on this, we then tested out a magnesium wire in the carotid artery of rats, mimicking the human experience of stroke. The results indicated that this method successfully helped reduce behavioral issues, neural damage, and even blood-brain barrier disruption in the rats following a known stroke model.
In conclusion, magnesium-based implants may represent a promising local treatment option for alleviating the damage caused by strokes, bolstering support for using magnesium in neuroprotection.
To do this, we first looked at how pure magnesium affected neuron cells that had undergone oxygen-glucose deprivation and reoxygenation. Encouragingly, we found that the magnesium could indeed protect these cells from injury.
Building on this, we then tested out a magnesium wire in the carotid artery of rats, mimicking the human experience of stroke. The results indicated that this method successfully helped reduce behavioral issues, neural damage, and even blood-brain barrier disruption in the rats following a known stroke model.
In conclusion, magnesium-based implants may represent a promising local treatment option for alleviating the damage caused by strokes, bolstering support for using magnesium in neuroprotection.
7.5
Calming effect noted
Most Useful Review
I can feel the calming effect of magnesium, which is vital for normal bone structure. Low levels of magnesium are linked to various diseases, including osteoporosis, high blood pressure, heart disease, diabetes, and stroke. These pills are easy to take, and I felt the calming effects within 30 minutes. I opted for this after my last physical showed slightly elevated LDL levels, and I’ll post my next test results as an update.
Autoimmune Disorder details
SCIENTIFIC SCORE
Moderately Effective
Based on 10 Researches
8.4
USERS' SCORE
Good
Based on 47 Reviews
8.3
9
Magnesium shows promise for RA treatment
Magnesium Supplementation Modifies Arthritis Synovial and Splenic Transcriptomic Signatures Including Ferroptosis and Cell Senescence Biological Pathways.
Most Relevant Research
We analyzed how magnesium supplementation affects the biology of rheumatoid arthritis (RA) in mice. By feeding one group a diet rich in magnesium and another a standard diet over 15 days, we examined changes in their tissue responses.
Our findings revealed that increased magnesium intake may alter gene expression linked to oxidative stress and cellular aging, processes that are significant in RA development. This suggests that magnesium could be beneficial for managing RA and potentially other autoimmune disorders by reducing disease severity and joint damage.
Our findings revealed that increased magnesium intake may alter gene expression linked to oxidative stress and cellular aging, processes that are significant in RA development. This suggests that magnesium could be beneficial for managing RA and potentially other autoimmune disorders by reducing disease severity and joint damage.
9.5
Emotional stability
Most Useful Review
I noticed various forms of magnesium in this product, although the manufacturer did not specify their ratios. After a month, I've felt remarkably calmer, observing that the emotional reactions of others no longer affect me as they did before. However, it's essential to consult with a doctor before using it to ensure it's right for your autoimmune disorder.
Diabetes details
SCIENTIFIC SCORE
Possibly Effective
Based on 19 Researches
7.5
USERS' SCORE
Good
Based on 9 Reviews
8.3
8
Magnesium intake benefits diabetes patients
Associations of dietary magnesium intake with the risk of atherosclerotic cardiovascular disease and mortality in individuals with and without type 2 diabetes: A prospective study in the UK Biobank.
Most Relevant Research
We investigated the link between dietary magnesium intake and the risk of heart disease and death in over 149,000 individuals, including those with type 2 diabetes. Through careful analysis over a median of 12 years, we found that higher magnesium intake was associated with significantly lower risks of heart disease and mortality in individuals with diabetes.
However, this benefit wasn't seen in those without diabetes. Our findings highlight the potential for magnesium to play a crucial role in health management for people living with type 2 diabetes, signaling the need for tailored dietary guidance.
However, this benefit wasn't seen in those without diabetes. Our findings highlight the potential for magnesium to play a crucial role in health management for people living with type 2 diabetes, signaling the need for tailored dietary guidance.
9.5
Diabetes risk reduction
Most Useful Review
Magnesium is a vital mineral involved in numerous biochemical reactions. It helps convert food into energy, synthesise DNA and proteins, and conduct nerve impulses. Without sufficient magnesium, risks of cardiovascular diseases, hypertension, osteoporosis, and type 2 diabetes increase. The dosage is good, lasting for 100 days of usage.
Heart Attack details
SCIENTIFIC SCORE
Questionable
Based on 23 Researches
6.6
USERS' SCORE
Good
Based on 13 Reviews
8.3
9
Magnesium implantation improves heart recovery
Magnesium implantation as a continuous hydrogen production generator for the treatment of myocardial infarction in rats.
Most Relevant Research
We explored the potential of magnesium implantation as a new approach to combat heart attacks, specifically myocardial infarction (MI). Our research centered on using magnesium slices implanted under the skin of rats to generate hydrogen gas continuously. This method could ensure a greater and longer-lasting concentration of hydrogen directly reaching the heart, which is crucial for its therapeutic effects.
Through our study, we measured how effectively the magnesium produced hydrogen and evaluated its safety. The results were promising; we observed that magnesium implantation not only improved cardiac function in rats suffering from MI, but also played a role in eliminating harmful free radicals from mitochondrial dysfunction. Furthermore, it helped reduce cell death in heart muscle cells, which is a common consequence of heart attacks.
Compared to traditional hydrogen inhalation, which has limitations in delivering sufficient doses over time, magnesium implantation proved to be a superior method. Overall, our findings pave the way for innovative treatments that could enhance recovery after heart attacks by harnessing the unique properties of magnesium for hydrogen production.
Through our study, we measured how effectively the magnesium produced hydrogen and evaluated its safety. The results were promising; we observed that magnesium implantation not only improved cardiac function in rats suffering from MI, but also played a role in eliminating harmful free radicals from mitochondrial dysfunction. Furthermore, it helped reduce cell death in heart muscle cells, which is a common consequence of heart attacks.
Compared to traditional hydrogen inhalation, which has limitations in delivering sufficient doses over time, magnesium implantation proved to be a superior method. Overall, our findings pave the way for innovative treatments that could enhance recovery after heart attacks by harnessing the unique properties of magnesium for hydrogen production.
9.5
Reduces heart issues
Most Useful Review
Life Extension's magnesium supplement is fantastic. It aids in recovery and alleviates stress due to deficiencies. It helps with heart health and lowers blood pressure, enhances energy production, and improves sleep. This supplement also has anti-inflammatory benefits, making it a vital part of my diet.
Frozen Shoulder details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 12 Reviews
8.2
9.5
Migraine relief
Most Useful Review
After over 10 years of migraines due to atmospheric pressure and my frozen shoulder, I tried magnesium. Surprisingly, after just two days, my migraines vanished. It may not work for everyone, but if you're suffering from headaches, it's worth a shot.
Sleep Apnea details
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 70 Reviews
8.2
7
Magnesium's role in sleep apnea
Association between magnesium deficiency score and sleep quality in adults: A population-based cross-sectional study.
Most Relevant Research
We aimed to uncover the relationship between magnesium levels and sleep quality, particularly focusing on sleep apnea. Our study analyzed data from a large group of adults aged 20 and older, using a well-structured method to assess magnesium levels and the prevalence of sleep issues.
We found a notable connection between lower magnesium levels, measured as the magnesium depletion score (MDS), and the likelihood of experiencing sleep apnea. Specifically, individuals with higher MDS levels were significantly more likely to report sleep apnea, showing over three times the odds compared to those with adequate magnesium levels.
Interestingly, our research did not link magnesium deficiency to other sleep problems like insomnia or restless legs syndrome, suggesting a more complex relationship with sleep apnea alone. Additionally, we noticed that older adults with depressive symptoms showed a tendency toward excessive sleep rather than insufficient sleep.
While our findings highlight the association between magnesium deficiency and sleep apnea, they also point towards the potential of adequate magnesium intake in reducing this risk. This emphasizes the importance of maintaining proper magnesium levels for better sleep quality, especially in those at higher risk for sleep apnea.
We found a notable connection between lower magnesium levels, measured as the magnesium depletion score (MDS), and the likelihood of experiencing sleep apnea. Specifically, individuals with higher MDS levels were significantly more likely to report sleep apnea, showing over three times the odds compared to those with adequate magnesium levels.
Interestingly, our research did not link magnesium deficiency to other sleep problems like insomnia or restless legs syndrome, suggesting a more complex relationship with sleep apnea alone. Additionally, we noticed that older adults with depressive symptoms showed a tendency toward excessive sleep rather than insufficient sleep.
While our findings highlight the association between magnesium deficiency and sleep apnea, they also point towards the potential of adequate magnesium intake in reducing this risk. This emphasizes the importance of maintaining proper magnesium levels for better sleep quality, especially in those at higher risk for sleep apnea.
8.3
Calmer nights
Most Useful Review
Magnesium helps me achieve restful sleep at night and calms my nervous system effectively.
Swollen Lymph Nodes details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 12 Reviews
8.1
10
Pleasant results
Most Useful Review
Excellent! I take a capsule at night. My legs were extremely swollen from standing all day. Now there's no swelling, and I am very pleased with my choice.
Chest Pain details
SCIENTIFIC SCORE
Possibly Effective
Based on 19 Researches
7.1
USERS' SCORE
Moderately Good
Based on 13 Reviews
7.8
8
Magnesium improves chest pain outcomes
Effects of oral magnesium therapy on exercise tolerance, exercise-induced chest pain, and quality of life in patients with coronary artery disease.
Most Relevant Research
We examined how oral magnesium might enhance quality of life and reduce exercise-induced chest pain for those with coronary artery disease (CAD). In an impressive multicenter trial, 187 patients were randomly assigned to receive either magnesium supplements or a placebo for six months.
Our findings show that magnesium therapy improved exercise duration and decreased chest pain during exertion. Participants receiving magnesium reported both enhanced exercise tolerance and better quality of life compared to those on a placebo. This suggests that magnesium supplementation could play an important role in managing CAD symptoms.
Our findings show that magnesium therapy improved exercise duration and decreased chest pain during exertion. Participants receiving magnesium reported both enhanced exercise tolerance and better quality of life compared to those on a placebo. This suggests that magnesium supplementation could play an important role in managing CAD symptoms.
9.5
Reduced chest pain
Most Useful Review
I was admitted to hospital at 16 weeks pregnant due to uterine hypertonicity and severe stomach pain, which no one could explain. I visited an osteopath, but after trying various medications, my doctor advised magnesium. I took one tablet daily, and my spasms began to reduce after three days. My bowel movements improved, and I felt much better overall. Now at 23 weeks, I no longer have uterine tension or any worries.
Constipation details
SCIENTIFIC SCORE
Questionable
Based on 22 Researches
6.8
USERS' SCORE
Moderately Good
Based on 142 Reviews
7.7
9
Effective treatment for chronic constipation
Senna Versus Magnesium Oxide for the Treatment of Chronic Constipation: A Randomized, Placebo-Controlled Trial.
Most Relevant Research
We explored the effectiveness of magnesium oxide (MgO) as a treatment for chronic constipation using a robust randomized, placebo-controlled trial. Over 28 days, participants received MgO, senna, or a placebo.
Both MgO and senna significantly improved bowel movement frequency and quality of life compared to placebo. About 68.3% of those using MgO reported symptom improvement, showcasing its potential as an effective osmotic agent alongside a stimulant laxative.
Importantly, there were no severe treatment-related side effects reported during the trial.
Both MgO and senna significantly improved bowel movement frequency and quality of life compared to placebo. About 68.3% of those using MgO reported symptom improvement, showcasing its potential as an effective osmotic agent alongside a stimulant laxative.
Importantly, there were no severe treatment-related side effects reported during the trial.
10
Constipation relief
Most Useful Review
I suffered from migraines and initially dismissed magnesium supplements. However, after trying this, my constipation disappeared within two days, and I lost 3 kg. My headaches have reduced significantly, making my days easier. I now recommend it to friends.
High Cholesterol details
SCIENTIFIC SCORE
Moderately Effective
Based on 9 Researches
8
USERS' SCORE
Moderately Good
Based on 12 Reviews
7.7
9
Magnesium chloride reduces liver stress
Protective Effects of Magnesium Chloride on Liver Enzymes and Biomarkers of Oxidative Stress in high fat diet fed Rats.
Most Relevant Research
We aimed to find out how magnesium chloride influences liver health and oxidative stress in rats on a high-fat diet.
In our study, groups of rats were fed either a normal diet, a high-fat diet, or a high-fat diet supplemented with magnesium chloride.
We found that those receiving magnesium showed lower levels of liver enzymes and oxidative stress markers compared to the high-fat diet group alone.
This suggests that magnesium chloride could help protect against the harmful effects of a high-fat diet, although its efficacy in humans needs further investigation.
In our study, groups of rats were fed either a normal diet, a high-fat diet, or a high-fat diet supplemented with magnesium chloride.
We found that those receiving magnesium showed lower levels of liver enzymes and oxidative stress markers compared to the high-fat diet group alone.
This suggests that magnesium chloride could help protect against the harmful effects of a high-fat diet, although its efficacy in humans needs further investigation.
9.5
Cramps alleviated
Most Useful Review
This magnesium is highly dosed and compatible, presented at a great price. I used to suffer from calf cramps at night, but since taking these capsules, they have disappeared entirely.
Food Poisoning details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 3 Reviews
7.5
9.5
Effective for constipation
Most Useful Review
It really helps. I used magnesium citrate as an oral laxative when nothing else worked. My doctor prescribed it after I experienced constipation due to travel and food poisoning. After taking a 10 oz bottle at 4 p.m., I felt the urge to go to the toilet by 10 p.m., which continued until 5 a.m. This product is strong but highly effective.
Pelvic Pain details
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.3
USERS' SCORE
Moderately Good
Based on 23 Reviews
7.4
8
Magnesium alleviates primary dysmenorrhea
Effectiveness of magnesium pidolate in the prophylactic treatment of primary dysmenorrhea.
Most Relevant Research
We evaluated how magnesium pidolate impacts primary dysmenorrhea in 30 young women. Over six menstrual cycles, we tracked their pain levels using a visual scale. Initially, no treatment was given, and subsequently, magnesium was administered just before menstruation.
The first day of menstrual pain showed a notable decrease with magnesium treatment, especially from the first to the sixth cycle. While there were some improvements on days two and three, those weren't statistically significant. Importantly, no side effects were reported, suggesting magnesium can be a reliable option for managing menstrual pain.
The first day of menstrual pain showed a notable decrease with magnesium treatment, especially from the first to the sixth cycle. While there were some improvements on days two and three, those weren't statistically significant. Importantly, no side effects were reported, suggesting magnesium can be a reliable option for managing menstrual pain.
9.5
Improved pelvic pain
Most Useful Review
Saved from cramps during pregnancy. At 16 weeks, I was admitted with uterine hypertonicity. The pain continued, and various medications did not help. The doctor advised magnesium, which I took daily. Within three days, my symptoms improved significantly. Now at 23 weeks, I feel great with no more tone or discomfort.
Irritable Bowel Syndrome details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Medium or Average
Based on 55 Reviews
6.9
8
Magnesium boosts colonic activity
Effects of oral magnesium sulphate on colonic motility in patients with the irritable bowel syndrome.
Most Relevant Research
We set out to understand how magnesium sulphate influences the symptoms of irritable bowel syndrome (IBS). In a study involving 20 IBS patients, magnesium sulphate was administered orally, resulting in a quick boost in colonic motor activity. Most participants experienced this increase within just two to six minutes.
Specifically, the percentage of colonic activity rose from 16.2% to 23.7%, signaling a notable change. Those who often felt abdominal pain after eating showed even more pronounced reactions, with their activity jumping from 16.1% to 29.8%. However, it’s important to note that three of these patients still experienced their usual pain after taking magnesium, suggesting that while magnesium can enhance motility, it doesn’t eliminate the pain for everyone.
Ultimately, these findings lend support to the idea that some cases of abdominal pain related to food may stem from heightened intestinal responses to cholecystokinin, a hormone released by the intestine. So while magnesium shows promise for intriguing changes in colonic movement in IBS patients, its effectiveness in alleviating pain remains mixed.
Specifically, the percentage of colonic activity rose from 16.2% to 23.7%, signaling a notable change. Those who often felt abdominal pain after eating showed even more pronounced reactions, with their activity jumping from 16.1% to 29.8%. However, it’s important to note that three of these patients still experienced their usual pain after taking magnesium, suggesting that while magnesium can enhance motility, it doesn’t eliminate the pain for everyone.
Ultimately, these findings lend support to the idea that some cases of abdominal pain related to food may stem from heightened intestinal responses to cholecystokinin, a hormone released by the intestine. So while magnesium shows promise for intriguing changes in colonic movement in IBS patients, its effectiveness in alleviating pain remains mixed.
9.5
Regulated bowel transit
Most Useful Review
My wife has irritable bowel syndrome and struggled with constipation. After trying various methods, this supplement has resolved her issues. Previously, she would go four to five days without a bowel movement, but now she goes twice daily. The quality of this magnesium complex is excellent and it's easy to take.
Athlete’s Foot details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Medium or Average
Based on 3 Reviews
6.7
9.5
Leg cramps alleviated
Most Useful Review
No more leg cramps after switching to a keto lifestyle. I faced severe cramps and constipation, but since I began taking Life Extension magnesium supplements, I've only experienced one episode of cramps at night. Increasing my intake from one to two capsules has effectively resolved the issue.
