' 
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.7
USERS' SCORE
Good
Based on 2 Reviews
8.5
Supplement Facts
Serving Size: 1 Vegetarian Capsule
Amount Per Serving
%DV
Vitamin C (from ascorbic acid, camu-camu berry extract)
30 mg
33%
Quercetin (as quercetin dihydrate)
250 mg
**
Optimized Food Blend[onion (bulb) (extracts), bitter orange bioflavonoids (peel and fruit), apple (fruit)
220 mg
**
Camu-camu extract (wildcrafted berry)
50 mg
**
Top Medical Research Studies
7
Quercetin shows promise for psoriasis
Inhibition of PI3K/AKT/GLUT1 Signaling Pathway by Quercetin in the Treatment of Psoriasis.
Focus on quercetin's isolated effects
We set out to explore the therapeutic impact of quercetin on psoriasis and how it interacts with a specific signaling pathway known as PI3K/AKT/GLUT1, which plays a critical role in inflammation and immune responses. Using a mouse model of psoriasis induced by imiquimod, we carefully assessed the effects of quercetin on skin lesions and associated histopathological features.
To deepen our understanding, we evaluated human keratinocyte cells (HaCaT) to see how quercetin influenced cell proliferation and apoptosis. Our findings indicated that quercetin appeared helpful in reducing the symptoms of psoriasis and that it had a notable effect on signaling through the PI3K/AKT/GLUT1 pathway.
Overall, the results suggest that quercetin could be a promising candidate for treating psoriasis, marking a step forward in potential therapeutic options. As we continue to investigate this area, these insights may pave the way for more targeted treatments in the future.
To deepen our understanding, we evaluated human keratinocyte cells (HaCaT) to see how quercetin influenced cell proliferation and apoptosis. Our findings indicated that quercetin appeared helpful in reducing the symptoms of psoriasis and that it had a notable effect on signaling through the PI3K/AKT/GLUT1 pathway.
Overall, the results suggest that quercetin could be a promising candidate for treating psoriasis, marking a step forward in potential therapeutic options. As we continue to investigate this area, these insights may pave the way for more targeted treatments in the future.
Read More
8
Quercetin reduces psoriasis inflammation
Quercetin mediates the therapeutic effect of on psoriasis by regulating STAT3 phosphorylation to inhibit the IL-23/IL-17A axis.
Direct evaluation of quercetin effects
Our exploration focused on understanding how quercetin, along with other components, contributes to treating psoriasis. The study involved utilizing various databases to identify compounds and their targets, followed by creating a network to visualize these interactions.
We examined the effects of quercetin and found that it effectively reduces the production of inflammatory substances like NO, TNF-α, and IL-6. Additionally, quercetin appeared to impact critical inflammatory pathways, particularly by regulating the IL-23/IL-17A axis through the phospho-STAT3 pathway. This regulation is significant, as it suggests quercetin's potential in managing psoriasis symptoms by dampening the inflammatory response.
Overall, our findings highlight quercetin, along with asiaticoside and asiatic acid, as key players in addressing psoriasis. However, quercetin stands out for its specific impact on modulating inflammatory markers, which presents a promising direction for future treatments.
We examined the effects of quercetin and found that it effectively reduces the production of inflammatory substances like NO, TNF-α, and IL-6. Additionally, quercetin appeared to impact critical inflammatory pathways, particularly by regulating the IL-23/IL-17A axis through the phospho-STAT3 pathway. This regulation is significant, as it suggests quercetin's potential in managing psoriasis symptoms by dampening the inflammatory response.
Overall, our findings highlight quercetin, along with asiaticoside and asiatic acid, as key players in addressing psoriasis. However, quercetin stands out for its specific impact on modulating inflammatory markers, which presents a promising direction for future treatments.
Read More
8
Quercetin's potential in psoriasis
Unveiling the molecular mechanisms of Haitang-Xiaoyin Mixture in psoriasis treatment based on bioinformatics, network pharmacology, machine learning, and molecular docking verification.
Addresses quercetin's psoriasis effects
We examined the therapeutic effects of quercetin, a key component of the traditional Chinese medicine formulation known as Haitang-Xiaoyin Mixture (HXM), on psoriasis. The study utilized advanced approaches, including bioinformatics and network pharmacology, to identify the specific targets and mechanisms of action that quercetin may have in managing this skin condition.
Our findings illuminated that quercetin, along with another component called triptolide, interacts with important proteins in the body known to be involved in psoriasis. Notably, we pinpointed CXCL2 and CXCR4 as critical targets affected by quercetin, suggesting that this compound plays an essential role in modulating immune responses and inflammation associated with psoriasis.
By employing methods like machine learning and molecular docking, we strengthened the understanding of how quercetin acts at a molecular level. This research reveals the promising potential of quercetin in alleviating psoriasis symptoms, although we should carefully consider its effects in conjunction with other compounds present in HXM.
Our findings illuminated that quercetin, along with another component called triptolide, interacts with important proteins in the body known to be involved in psoriasis. Notably, we pinpointed CXCL2 and CXCR4 as critical targets affected by quercetin, suggesting that this compound plays an essential role in modulating immune responses and inflammation associated with psoriasis.
By employing methods like machine learning and molecular docking, we strengthened the understanding of how quercetin acts at a molecular level. This research reveals the promising potential of quercetin in alleviating psoriasis symptoms, although we should carefully consider its effects in conjunction with other compounds present in HXM.
Read More
Most Useful Reviews
8
Improved immune function
Great product! I've noticed a difference at week four with some inflammation in my joints and reduced flare-ups of psoriasis on my face. I haven't been ill yet, despite winter approaching and my two young kids having minor colds, indicating that my immune system seems to be functioning better as well.
Read More
8.8
Reduced psoriasis irritation
Great product! I've been using Life Extension's Optimised Quercetin for a few weeks now, and I've noticed a remarkable improvement in my overall well-being. As someone who deals with occasional joint inflammation and seasonal allergies, this supplement has made a noticeable difference. By week four, I experienced reduced joint flare-ups and less irritation from my psoriasis, particularly on my face. My immune system has held strong, and I haven't fallen ill despite my kids bringing home minor colds. What I really love about this product is its versatility; it's also helped with respiratory issues. The antioxidant properties of quercetin have contributed to reduced inflammation, and I've felt more energised throughout the day. Life Extension's commitment to quality is evident, and this supplement has become a staple in my daily routine.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.7
- All Researches
8
Quercetin's potential in psoriasis
Unveiling the molecular mechanisms of Haitang-Xiaoyin Mixture in psoriasis treatment based on bioinformatics, network pharmacology, machine learning, and molecular docking verification.
Addresses quercetin's psoriasis effects
We examined the therapeutic effects of quercetin, a key component of the traditional Chinese medicine formulation known as Haitang-Xiaoyin Mixture (HXM), on psoriasis. The study utilized advanced approaches, including bioinformatics and network pharmacology, to identify the specific targets and mechanisms of action that quercetin may have in managing this skin condition.
Our findings illuminated that quercetin, along with another component called triptolide, interacts with important proteins in the body known to be involved in psoriasis. Notably, we pinpointed CXCL2 and CXCR4 as critical targets affected by quercetin, suggesting that this compound plays an essential role in modulating immune responses and inflammation associated with psoriasis.
By employing methods like machine learning and molecular docking, we strengthened the understanding of how quercetin acts at a molecular level. This research reveals the promising potential of quercetin in alleviating psoriasis symptoms, although we should carefully consider its effects in conjunction with other compounds present in HXM.
Our findings illuminated that quercetin, along with another component called triptolide, interacts with important proteins in the body known to be involved in psoriasis. Notably, we pinpointed CXCL2 and CXCR4 as critical targets affected by quercetin, suggesting that this compound plays an essential role in modulating immune responses and inflammation associated with psoriasis.
By employing methods like machine learning and molecular docking, we strengthened the understanding of how quercetin acts at a molecular level. This research reveals the promising potential of quercetin in alleviating psoriasis symptoms, although we should carefully consider its effects in conjunction with other compounds present in HXM.
Read More
8
Quercetin reduces psoriasis inflammation
Quercetin mediates the therapeutic effect of on psoriasis by regulating STAT3 phosphorylation to inhibit the IL-23/IL-17A axis.
Direct evaluation of quercetin effects
Our exploration focused on understanding how quercetin, along with other components, contributes to treating psoriasis. The study involved utilizing various databases to identify compounds and their targets, followed by creating a network to visualize these interactions.
We examined the effects of quercetin and found that it effectively reduces the production of inflammatory substances like NO, TNF-α, and IL-6. Additionally, quercetin appeared to impact critical inflammatory pathways, particularly by regulating the IL-23/IL-17A axis through the phospho-STAT3 pathway. This regulation is significant, as it suggests quercetin's potential in managing psoriasis symptoms by dampening the inflammatory response.
Overall, our findings highlight quercetin, along with asiaticoside and asiatic acid, as key players in addressing psoriasis. However, quercetin stands out for its specific impact on modulating inflammatory markers, which presents a promising direction for future treatments.
We examined the effects of quercetin and found that it effectively reduces the production of inflammatory substances like NO, TNF-α, and IL-6. Additionally, quercetin appeared to impact critical inflammatory pathways, particularly by regulating the IL-23/IL-17A axis through the phospho-STAT3 pathway. This regulation is significant, as it suggests quercetin's potential in managing psoriasis symptoms by dampening the inflammatory response.
Overall, our findings highlight quercetin, along with asiaticoside and asiatic acid, as key players in addressing psoriasis. However, quercetin stands out for its specific impact on modulating inflammatory markers, which presents a promising direction for future treatments.
Read More
7
Quercetin shows promise for psoriasis
Inhibition of PI3K/AKT/GLUT1 Signaling Pathway by Quercetin in the Treatment of Psoriasis.
Focus on quercetin's isolated effects
We set out to explore the therapeutic impact of quercetin on psoriasis and how it interacts with a specific signaling pathway known as PI3K/AKT/GLUT1, which plays a critical role in inflammation and immune responses. Using a mouse model of psoriasis induced by imiquimod, we carefully assessed the effects of quercetin on skin lesions and associated histopathological features.
To deepen our understanding, we evaluated human keratinocyte cells (HaCaT) to see how quercetin influenced cell proliferation and apoptosis. Our findings indicated that quercetin appeared helpful in reducing the symptoms of psoriasis and that it had a notable effect on signaling through the PI3K/AKT/GLUT1 pathway.
Overall, the results suggest that quercetin could be a promising candidate for treating psoriasis, marking a step forward in potential therapeutic options. As we continue to investigate this area, these insights may pave the way for more targeted treatments in the future.
To deepen our understanding, we evaluated human keratinocyte cells (HaCaT) to see how quercetin influenced cell proliferation and apoptosis. Our findings indicated that quercetin appeared helpful in reducing the symptoms of psoriasis and that it had a notable effect on signaling through the PI3K/AKT/GLUT1 pathway.
Overall, the results suggest that quercetin could be a promising candidate for treating psoriasis, marking a step forward in potential therapeutic options. As we continue to investigate this area, these insights may pave the way for more targeted treatments in the future.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
8
Improved immune function
Great product! I've noticed a difference at week four with some inflammation in my joints and reduced flare-ups of psoriasis on my face. I haven't been ill yet, despite winter approaching and my two young kids having minor colds, indicating that my immune system seems to be functioning better as well.
Read More
8.8
Reduced psoriasis irritation
Great product! I've been using Life Extension's Optimised Quercetin for a few weeks now, and I've noticed a remarkable improvement in my overall well-being. As someone who deals with occasional joint inflammation and seasonal allergies, this supplement has made a noticeable difference. By week four, I experienced reduced joint flare-ups and less irritation from my psoriasis, particularly on my face. My immune system has held strong, and I haven't fallen ill despite my kids bringing home minor colds. What I really love about this product is its versatility; it's also helped with respiratory issues. The antioxidant properties of quercetin have contributed to reduced inflammation, and I've felt more energised throughout the day. Life Extension's commitment to quality is evident, and this supplement has become a staple in my daily routine.
Read More
