' 
SCIENTIFIC SCORE
Most Likely Effective
Based on 13 Researches
7.4
USERS' SCORE
Very Good
Based on 2 Reviews
8.2
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
10
Total Fat
1 g
1%
Saturated Fat
0 g
0%
Trans Fat
0 g
**
Polyunsaturated Fat
0.5 g
**
Monounsaturated Fat
0 g
**
Cholesterol
10 mg
3%
Omega-3 Fish Oil
1000 mg
**
EPA (Eicosapentaenoic Acid)
180 mg
**
DHA (Docosahexaenoic Acid)
120 mg
**
Top Medical Research Studies
8
SC411 boosts survival in SCD
SC411 treatment can enhance survival in a mouse model of sickle cell disease.
Focus on eicosapentaenoic acid
We explored how a treatment called SC411, which is enriched with eicosapentaenoic acid (EPA), impacts anemia in a specific mouse model of sickle cell disease (SCD). SCD often leads to severe anemia and other serious health issues. Our investigation revealed that SC411 increased the levels of both docosahexaenoic acid (DHA) and EPA in the blood, which are essential fatty acids known to have beneficial effects on health.
Furthermore, we observed that SC411 helped decrease harmful arachidonic acid levels and reduced the sickling of red blood cells, thereby potentially alleviating some of the pain and complications associated with the disease. The treatment not only improved cerebral blood flow but also seemed to enhance cognitive functions, like memory, in the mice.
Overall, the results highlighted that treatment with SC411 could significantly enhance survival rates in mice with SCD through improved cellular and functional outcomes, paving the way for new therapeutic strategies to handle ischemic injuries related to this debilitating condition.
Furthermore, we observed that SC411 helped decrease harmful arachidonic acid levels and reduced the sickling of red blood cells, thereby potentially alleviating some of the pain and complications associated with the disease. The treatment not only improved cerebral blood flow but also seemed to enhance cognitive functions, like memory, in the mice.
Overall, the results highlighted that treatment with SC411 could significantly enhance survival rates in mice with SCD through improved cellular and functional outcomes, paving the way for new therapeutic strategies to handle ischemic injuries related to this debilitating condition.
Read More
8
Eicosapentaenoic acid benefits anemia
Steady-state haemoglobin level in sickle cell anaemia increases with an increase in erythrocyte membrane n-3 fatty acids.
Significant correlation observed
We explored how eicosapentaenoic acid (EPA) relates to anemia in patients with sickle cell disease (SCD). The study compared blood fatty acids in 43 individuals with homozygous sickle cell disease (HbSS) to 43 healthy controls.
Our analysis revealed that patients with SCD had higher levels of certain n-6 fatty acids, but notably lower amounts of EPA and docosahexaenoic acid (DHA). Interestingly, we found a positive correlation between the steady-state hemoglobin levels and the presence of DHA and EPA in the red blood cell membranes of the patients. These findings suggest that incorporating EPA and DHA into their diets could help improve anemia.
This imbalance in fatty acids highlights a potential area for dietary intervention. By correcting this imbalance through supplementation, we might improve the health of individuals affected by this condition.
Our analysis revealed that patients with SCD had higher levels of certain n-6 fatty acids, but notably lower amounts of EPA and docosahexaenoic acid (DHA). Interestingly, we found a positive correlation between the steady-state hemoglobin levels and the presence of DHA and EPA in the red blood cell membranes of the patients. These findings suggest that incorporating EPA and DHA into their diets could help improve anemia.
This imbalance in fatty acids highlights a potential area for dietary intervention. By correcting this imbalance through supplementation, we might improve the health of individuals affected by this condition.
Read More
8
Eicosapentaenoic acid reduces anemia
Antimalarial properties of n-3 and n-6 polyunsaturated fatty acids: in vitro effects on Plasmodium falciparum and in vivo effects on P. berghei.
Relevant to malaria treatment study.
The study we reviewed focused on the effects of eicosapentaenoic acid (EPA) on anemia related to malaria infection. Using a model with mice infected by the Plasmodium berghei parasite, we observed promising results over a period of four days.
Specifically, treatment with EPA led to a noticeable decrease in parasitemia, which refers to the presence of parasites in the blood. Not only did EPA show effectiveness in combating the parasite, but it also helped alleviate the anemia associated with this infection. This is particularly significant because anemia can complicate the recovery process in patients suffering from malaria.
Moreover, the study emphasized that while EPA and other polyunsaturated fatty acids demonstrate potential therapeutic benefits, the results provide a starting point for future research. We believe this information can inspire new approaches toward treating malaria and its related conditions.
Specifically, treatment with EPA led to a noticeable decrease in parasitemia, which refers to the presence of parasites in the blood. Not only did EPA show effectiveness in combating the parasite, but it also helped alleviate the anemia associated with this infection. This is particularly significant because anemia can complicate the recovery process in patients suffering from malaria.
Moreover, the study emphasized that while EPA and other polyunsaturated fatty acids demonstrate potential therapeutic benefits, the results provide a starting point for future research. We believe this information can inspire new approaches toward treating malaria and its related conditions.
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Most Useful Reviews
8.8
Helps with fatigue
This product is amazing and very helpful. I no longer feel fatigued, and it’s excellent for anaemia as it contains fish oil.
Read More
8
Supports treating anemia
Food for the brain! I have taken dietary supplements for 18 years and found fish oil particularly beneficial for various health aspects. It enhances vision, memory, strengthens immunity, lowers blood pressure, and promotes cell regeneration. My therapist recommended it for stabilising cholesterol levels and addressing mild anaemia. We all take two capsules each morning with meals, and I highly recommend it. The quality is great, and it’s much cheaper than at local pharmacies.
Read More
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Medical Researches
SCIENTIFIC SCORE
Most Likely Effective
Based on 13 Researches
7.4
9
EPA may prevent anemia risk
Prophylaxis for ribavirin-related anemia using eicosapentaenoic acid in chronic hepatitis C patients.
Relevant study on EPA and anemia
We examined the effectiveness of eicosapentaenoic acid (EPA) in preventing anemia caused by ribavirin during hepatitis C treatment. This study involved twelve chronic hepatitis C patients, aged between 3 and 21 years, who were divided into two groups: one receiving EPA and the other acting as a control. Blood samples were collected at various intervals to monitor changes in hemoglobin levels and ribavirin concentrations throughout the treatment period.
Our findings revealed that those who received EPA experienced significantly less reduction in hemoglobin levels compared to the control group. In fact, by weeks eight and sixteen, the protective effects against anemia were clear and statistically significant. While we did not observe any notable differences in ribavirin drug levels between the two groups, one patient in the control group had to lower their ribavirin dosage due to anemia.
Overall, our research underscores the potential of EPA supplementation as a preventative measure against ribavirin-related anemia in young patients undergoing treatment for hepatitis C. This offers a promising strategy to improve treatment adherence and outcomes for this vulnerable population.
Our findings revealed that those who received EPA experienced significantly less reduction in hemoglobin levels compared to the control group. In fact, by weeks eight and sixteen, the protective effects against anemia were clear and statistically significant. While we did not observe any notable differences in ribavirin drug levels between the two groups, one patient in the control group had to lower their ribavirin dosage due to anemia.
Overall, our research underscores the potential of EPA supplementation as a preventative measure against ribavirin-related anemia in young patients undergoing treatment for hepatitis C. This offers a promising strategy to improve treatment adherence and outcomes for this vulnerable population.
Read More
8
Omega-3 enhances anemia treatment
Comparative effectiveness of adding omega-3 and Manuka honey combination to conventional therapy in preventing and treating oxidative stress in pediatric β-thalassemia major - a randomized clinical trial.
Investigates omega-3 for anemia
We explored the effectiveness of adding omega-3 fish oil, specifically its components eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), along with Manuka honey, to conventional therapies in treating oxidative stress in children with β-thalassemia major. In this study, 165 pediatric patients were involved in a randomized, double-blind trial. They were divided into three groups: one received a combination of omega-3 and Manuka honey, while another group got just Manuka honey, and a third group followed standard treatment alone.
Throughout the ten-month study period, we measured various markers of oxidative stress and overall health in these children. Our findings revealed that the combination of omega-3 and Manuka honey showed more effectiveness in managing oxidative stress than either Manuka honey alone or the conventional treatment. This suggests that integrating omega-3 into their treatment plan could offer better outcomes for managing the health challenges associated with β-thalassemia.
Ultimately, our research highlights the potential role of omega-3 as a beneficial component in the treatment of anemia related to oxidative stress in pediatric patients. By addressing both oxidative stress and iron overload, we hope this approach leads to improved management strategies for young individuals dealing with this inherited condition.
Throughout the ten-month study period, we measured various markers of oxidative stress and overall health in these children. Our findings revealed that the combination of omega-3 and Manuka honey showed more effectiveness in managing oxidative stress than either Manuka honey alone or the conventional treatment. This suggests that integrating omega-3 into their treatment plan could offer better outcomes for managing the health challenges associated with β-thalassemia.
Ultimately, our research highlights the potential role of omega-3 as a beneficial component in the treatment of anemia related to oxidative stress in pediatric patients. By addressing both oxidative stress and iron overload, we hope this approach leads to improved management strategies for young individuals dealing with this inherited condition.
Read More
8
Eicosapentaenoic acid improves anemia
Adjunct n-3 Long-Chain Polyunsaturated Fatty Acid Treatment in Tuberculosis Reduces Inflammation and Improves Anemia of Infection More in C3HeB/FeJ Mice With Low n-3 Fatty Acid Status Than Sufficient n-3 Fatty Acid Status.
Study highlights EPA effectiveness.
We explored how eicosapentaenoic acid (EPA), a type of omega-3 fatty acid, influences anemia in mice suffering from tuberculosis (TB). The study compared two groups of mice with different levels of omega-3 fatty acids—one with a low status and another with a sufficient status. After being infected with TB, both groups were given additional EPA to see its impact alongside standard TB medications.
After 14 days of treatment, we observed that mice with low omega-3 levels showed improved hemoglobin levels compared to untreated mice with sufficient omega-3. Specifically, the low omega-3 group had higher hemoglobin, meaning they were potentially less anemic.
Furthermore, our findings revealed that the low omega-3 mice experienced lower levels of pro-inflammatory cytokines, which are markers for inflammation, indicating that EPA may help in reducing inflammation as well. This suggests that EPA can offer a dual benefit by improving anemia and mitigating inflammation during TB treatment, particularly in individuals who start with low omega-3 levels.
After 14 days of treatment, we observed that mice with low omega-3 levels showed improved hemoglobin levels compared to untreated mice with sufficient omega-3. Specifically, the low omega-3 group had higher hemoglobin, meaning they were potentially less anemic.
Furthermore, our findings revealed that the low omega-3 mice experienced lower levels of pro-inflammatory cytokines, which are markers for inflammation, indicating that EPA may help in reducing inflammation as well. This suggests that EPA can offer a dual benefit by improving anemia and mitigating inflammation during TB treatment, particularly in individuals who start with low omega-3 levels.
Read More
8
SC411 boosts survival in SCD
SC411 treatment can enhance survival in a mouse model of sickle cell disease.
Focus on eicosapentaenoic acid
We explored how a treatment called SC411, which is enriched with eicosapentaenoic acid (EPA), impacts anemia in a specific mouse model of sickle cell disease (SCD). SCD often leads to severe anemia and other serious health issues. Our investigation revealed that SC411 increased the levels of both docosahexaenoic acid (DHA) and EPA in the blood, which are essential fatty acids known to have beneficial effects on health.
Furthermore, we observed that SC411 helped decrease harmful arachidonic acid levels and reduced the sickling of red blood cells, thereby potentially alleviating some of the pain and complications associated with the disease. The treatment not only improved cerebral blood flow but also seemed to enhance cognitive functions, like memory, in the mice.
Overall, the results highlighted that treatment with SC411 could significantly enhance survival rates in mice with SCD through improved cellular and functional outcomes, paving the way for new therapeutic strategies to handle ischemic injuries related to this debilitating condition.
Furthermore, we observed that SC411 helped decrease harmful arachidonic acid levels and reduced the sickling of red blood cells, thereby potentially alleviating some of the pain and complications associated with the disease. The treatment not only improved cerebral blood flow but also seemed to enhance cognitive functions, like memory, in the mice.
Overall, the results highlighted that treatment with SC411 could significantly enhance survival rates in mice with SCD through improved cellular and functional outcomes, paving the way for new therapeutic strategies to handle ischemic injuries related to this debilitating condition.
Read More
8
Eicosapentaenoic acid’s mixed effects
n-3 Long-chain PUFAs reduce respiratory morbidity caused by iron supplementation in iron-deficient South African schoolchildren: a randomized, double-blind, placebo-controlled intervention.
Evaluates combined supplement impacts
We explored the potential effects of eicosapentaenoic acid (EPA) on anemia in a group of iron-deficient South African schoolchildren. In our study, 321 children, aged between 6 and 11 years, participated in a carefully designed trial where they were assigned to one of four groups. These groups either received iron supplements alone, EPA along with a placebo, a combination of iron and EPA, or just a placebo for a total of 8.5 months. This random and double-blind method ensured that we could precisely evaluate the impacts of these treatments.
Our findings revealed a concerning trend: while iron supplementation alone led to increased respiratory morbidity among the children, the combination of iron with EPA effectively prevented this increase. However, we should clarify that while we witnessed a decrease in respiratory issues when EPA was included, the study did not isolate the effects of EPA in terms of improving anemia by itself. Therefore, we cannot definitively state that EPA alone has a significant impact on anemia.
This research highlights the complexities of treating iron deficiency and suggests that adding EPA could provide a protective effect against specific health issues without directly addressing anemia. It’s important for future research to dive deeper into how EPA might play a role on its own in the context of anemia.
Our findings revealed a concerning trend: while iron supplementation alone led to increased respiratory morbidity among the children, the combination of iron with EPA effectively prevented this increase. However, we should clarify that while we witnessed a decrease in respiratory issues when EPA was included, the study did not isolate the effects of EPA in terms of improving anemia by itself. Therefore, we cannot definitively state that EPA alone has a significant impact on anemia.
This research highlights the complexities of treating iron deficiency and suggests that adding EPA could provide a protective effect against specific health issues without directly addressing anemia. It’s important for future research to dive deeper into how EPA might play a role on its own in the context of anemia.
Read More
User Reviews
USERS' SCORE
Very Good
Based on 2 Reviews
8.2
8.8
Helps with fatigue
This product is amazing and very helpful. I no longer feel fatigued, and it’s excellent for anaemia as it contains fish oil.
8
Supports treating anemia
Food for the brain! I have taken dietary supplements for 18 years and found fish oil particularly beneficial for various health aspects. It enhances vision, memory, strengthens immunity, lowers blood pressure, and promotes cell regeneration. My therapist recommended it for stabilising cholesterol levels and addressing mild anaemia. We all take two capsules each morning with meals, and I highly recommend it. The quality is great, and it’s much cheaper than at local pharmacies.
Read More
