Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 15 Researches
8.9
USERS' SCORE
Good
Based on 1 Review
8.4
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Vitamin D3 (as Cholecalciferol)
5 mcg (200 IU)
25%
Calcium (as Calcium Carbonate)
333 mg
26%
Magnesium (as Magnesium Oxide)
133 mg
32%
Zinc (as Zinc Sulfate)
5 mg
45%
Top Medical Research Studies
9
We observed a striking case involving a 76-year-old woman diagnosed with cervical cancer, who was treated with nedaplatin, a platinum-based chemotherapy drug. Shortly after starting her treatment, she experienced troubling symptoms, including numbness, dizziness, and a noticeable loss of appetite.
Upon investigation, we discovered low levels of calcium and magnesium in her blood, which were likely contributing to her symptoms. Thankfully, after administering intravenous calcium and magnesium, we saw a prompt improvement in both her mineral levels and her symptoms.
The case underscores the importance of monitoring electrolyte levels during chemotherapy treatments, such as nedaplatin. By focusing on these disturbances, healthcare providers can unveil potential diagnoses even when patients present with vague symptoms. Regular follow-ups during anticancer therapies could be crucial in effectively managing side effects such as dizziness.
Upon investigation, we discovered low levels of calcium and magnesium in her blood, which were likely contributing to her symptoms. Thankfully, after administering intravenous calcium and magnesium, we saw a prompt improvement in both her mineral levels and her symptoms.
The case underscores the importance of monitoring electrolyte levels during chemotherapy treatments, such as nedaplatin. By focusing on these disturbances, healthcare providers can unveil potential diagnoses even when patients present with vague symptoms. Regular follow-ups during anticancer therapies could be crucial in effectively managing side effects such as dizziness.
Read More
9
We sought to understand the impact of severe vitamin D deficiency on benign paroxysmal positional vertigo (BPPV), a common cause of dizziness. Previous studies showed a connection between low vitamin D levels and both the onset and recurrence of BPPV, but none had conclusively demonstrated that addressing this deficiency could lessen the recurrence of symptoms.
To examine this further, we included patients diagnosed with unilateral, idiopathic posterior canal BPPV and severe vitamin D deficiency, indicated by levels of 25-hydroxyvitamin D3 at or below 10 ng/ml. After thorough evaluations including hearing tests and balance assessments, we prescribed vitamin D therapy to our participants.
Over the following months, we monitored the changes in their vitamin D levels and followed up with them for 18 months to observe any recurrence of dizziness. Our findings revealed that patients who showed an improvement in their vitamin D levels experienced a significant reduction in the recurrence of BPPV symptoms.
This suggests that by addressing vitamin D deficiency, we can potentially offer a more effective approach to managing BPPV—lessening those troublesome dizzy spells that can really impact quality of life.
To examine this further, we included patients diagnosed with unilateral, idiopathic posterior canal BPPV and severe vitamin D deficiency, indicated by levels of 25-hydroxyvitamin D3 at or below 10 ng/ml. After thorough evaluations including hearing tests and balance assessments, we prescribed vitamin D therapy to our participants.
Over the following months, we monitored the changes in their vitamin D levels and followed up with them for 18 months to observe any recurrence of dizziness. Our findings revealed that patients who showed an improvement in their vitamin D levels experienced a significant reduction in the recurrence of BPPV symptoms.
This suggests that by addressing vitamin D deficiency, we can potentially offer a more effective approach to managing BPPV—lessening those troublesome dizzy spells that can really impact quality of life.
Read More
9
We conducted a double-blinded randomized controlled trial to explore the effects of Vitamin D3 on the recurrence of BPPV, a condition that causes dizziness in older adults.
Our study involved participants who were initially vitamin D3 deficient. They were divided into two groups: one receiving a treatment of Vitamin D3 and the other a placebo. Over 12 months, participants who received the vitamin showed an impressive 87% reduction in their BPPV recurrence rates compared to those on placebo. Additionally, they experienced a longer time before their first episode of dizziness returned.
However, when we compared the treatment group to those who were already vitamin D replete, we found no significant difference in terms of recurrence rates or dizziness severity scores. This suggests that while Vitamin D3 treatment can reduce episodes of BPPV, its benefits may not extend to all older adults, particularly if they already have adequate vitamin D levels.
Overall, our findings lay the groundwork for further research into Vitamin D3's role in treating BPPV, potentially informing future clinical practice to help reduce risks of falls in older adults.
Our study involved participants who were initially vitamin D3 deficient. They were divided into two groups: one receiving a treatment of Vitamin D3 and the other a placebo. Over 12 months, participants who received the vitamin showed an impressive 87% reduction in their BPPV recurrence rates compared to those on placebo. Additionally, they experienced a longer time before their first episode of dizziness returned.
However, when we compared the treatment group to those who were already vitamin D replete, we found no significant difference in terms of recurrence rates or dizziness severity scores. This suggests that while Vitamin D3 treatment can reduce episodes of BPPV, its benefits may not extend to all older adults, particularly if they already have adequate vitamin D levels.
Overall, our findings lay the groundwork for further research into Vitamin D3's role in treating BPPV, potentially informing future clinical practice to help reduce risks of falls in older adults.
Read More
Most Useful Reviews
7.5
Improved symptoms
393 people found this helpful
For years, I suffered from face flushing, anxiety, sleeplessness, fatigue, and dizziness. After researching magnesium deficiency, which I discussed with my doctor, I found this vitamin. After a couple of weeks, I noticed a reduction in my issues, and after a month, I felt much better. I no longer take medications and feel remarkable. This supplement has been transformative for me over the past three years.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 15 Researches
8.9
- All Researches
9.5
We explored how vitamin D3, coupled with antioxidant supplements, can help prevent recurrent cases of benign paroxysmal positional vertigo (BPPV), a common type of dizziness. In this multicentric trial involving 128 patients who experienced frequent episodes of BPPV, we organized participants into three groups based on their vitamin D levels and treatment.
The first group received vitamin D3 along with a combination of alpha-lipoic acid, Carnosine, and Zinc, as well as vitamins from the B group. The second group, with sufficient vitamin D but no supplementation, served as a control. Meanwhile, the third group had sufficient vitamin D and received a different antioxidant mix.
After a six-month follow-up, we observed a significant reduction in dizziness relapses only among those in the first group who had insufficient or deficient vitamin D levels prior to treatment. Unfortunately, the other groups did not show similar improvements. This highlights the importance of addressing vitamin D deficiency, especially for those prone to recurrent dizziness. However, we must be cautious, as the combination of different supplements makes it challenging to isolate the effects solely attributed to vitamin D3.
The first group received vitamin D3 along with a combination of alpha-lipoic acid, Carnosine, and Zinc, as well as vitamins from the B group. The second group, with sufficient vitamin D but no supplementation, served as a control. Meanwhile, the third group had sufficient vitamin D and received a different antioxidant mix.
After a six-month follow-up, we observed a significant reduction in dizziness relapses only among those in the first group who had insufficient or deficient vitamin D levels prior to treatment. Unfortunately, the other groups did not show similar improvements. This highlights the importance of addressing vitamin D deficiency, especially for those prone to recurrent dizziness. However, we must be cautious, as the combination of different supplements makes it challenging to isolate the effects solely attributed to vitamin D3.
Read More
9.5
We explored how normalization of vitamin D levels may impact the recurrence of dizziness caused by benign paroxysmal positional vertigo (BPPV). This case-control study included patients with a history of BPPV who had low serum vitamin D levels. We divided participants into two groups: one received additional vitamin D3, while both groups underwent Epley rehabilitation therapy.
Over the course of two months, the treatment group raised their vitamin D levels significantly, while the control group did not see any change. Following this treatment period, we observed a remarkable difference in the recurrence of BPPV attacks; the group receiving vitamin D3 experienced far fewer episodes compared to the control group.
Our results indicate that boosting vitamin D3 levels significantly reduces the number of recurrent dizziness episodes in patients with BPPV. This suggests that addressing vitamin D deficiency may play a key role in managing dizziness in affected patients.
Over the course of two months, the treatment group raised their vitamin D levels significantly, while the control group did not see any change. Following this treatment period, we observed a remarkable difference in the recurrence of BPPV attacks; the group receiving vitamin D3 experienced far fewer episodes compared to the control group.
Our results indicate that boosting vitamin D3 levels significantly reduces the number of recurrent dizziness episodes in patients with BPPV. This suggests that addressing vitamin D deficiency may play a key role in managing dizziness in affected patients.
Read More
9.5
We observed the intriguing connection between Meniere's disease (MD) and migraine-related dizziness in our study of a 5-year-old girl. She experienced a six-month struggle with left-sided hearing loss, which evolved into daily bouts of vertigo, headaches, and vomiting, fulfilling the criteria for definite MD.
After implementing a specialized six-week migraine diet and lifestyle plan that included riboflavin and magnesium, we noted a remarkable transformation. The child became symptom-free and achieved nearly normal hearing levels, leading us to consider that MD symptoms might be linked to vestibular migraine triggers.
This suggests that young patients with MD could greatly benefit from lifestyle and dietary adjustments aimed at managing migraine symptoms. While magnesium was part of this regimen, it’s essential to look at it as one component of a broader approach. The results invite further exploration into how dietary interventions may alleviate both cochlear and vestibular symptoms in Meniere's disease.
After implementing a specialized six-week migraine diet and lifestyle plan that included riboflavin and magnesium, we noted a remarkable transformation. The child became symptom-free and achieved nearly normal hearing levels, leading us to consider that MD symptoms might be linked to vestibular migraine triggers.
This suggests that young patients with MD could greatly benefit from lifestyle and dietary adjustments aimed at managing migraine symptoms. While magnesium was part of this regimen, it’s essential to look at it as one component of a broader approach. The results invite further exploration into how dietary interventions may alleviate both cochlear and vestibular symptoms in Meniere's disease.
Read More
9.5
We looked into the issue of persistent post-stapedotomy vertigo, or PSV, which can leave patients feeling dizzy for months after ear surgery. Over a span of ten years, we examined cases at a major hospital where patients reported ongoing dizziness for at least three months following their procedure.
Our findings included five patients who struggled with daily vertigo episodes, averaging 53 years old. They were treated with a combination of lifestyle and dietary changes alongside medications like nortriptyline and verapamil. Interestingly, vitamin B2 and magnesium were also part of the regimen.
After starting treatment, we noticed a remarkable turnaround. All five patients experienced a complete resolution of their vertigo over an average period of nine weeks. While magnesium was included in their treatment, we cannot definitively point to its isolated effect on dizziness, as it was used alongside other medications. Overall, our results hint that patients suffering from this type of vertigo might indeed benefit from migraine prophylaxis treatments, where magnesium could play a role, but more research is needed to isolate its impact specifically.
Our findings included five patients who struggled with daily vertigo episodes, averaging 53 years old. They were treated with a combination of lifestyle and dietary changes alongside medications like nortriptyline and verapamil. Interestingly, vitamin B2 and magnesium were also part of the regimen.
After starting treatment, we noticed a remarkable turnaround. All five patients experienced a complete resolution of their vertigo over an average period of nine weeks. While magnesium was included in their treatment, we cannot definitively point to its isolated effect on dizziness, as it was used alongside other medications. Overall, our results hint that patients suffering from this type of vertigo might indeed benefit from migraine prophylaxis treatments, where magnesium could play a role, but more research is needed to isolate its impact specifically.
Read More
9
We observed a striking case involving a 76-year-old woman diagnosed with cervical cancer, who was treated with nedaplatin, a platinum-based chemotherapy drug. Shortly after starting her treatment, she experienced troubling symptoms, including numbness, dizziness, and a noticeable loss of appetite.
Upon investigation, we discovered low levels of calcium and magnesium in her blood, which were likely contributing to her symptoms. Thankfully, after administering intravenous calcium and magnesium, we saw a prompt improvement in both her mineral levels and her symptoms.
The case underscores the importance of monitoring electrolyte levels during chemotherapy treatments, such as nedaplatin. By focusing on these disturbances, healthcare providers can unveil potential diagnoses even when patients present with vague symptoms. Regular follow-ups during anticancer therapies could be crucial in effectively managing side effects such as dizziness.
Upon investigation, we discovered low levels of calcium and magnesium in her blood, which were likely contributing to her symptoms. Thankfully, after administering intravenous calcium and magnesium, we saw a prompt improvement in both her mineral levels and her symptoms.
The case underscores the importance of monitoring electrolyte levels during chemotherapy treatments, such as nedaplatin. By focusing on these disturbances, healthcare providers can unveil potential diagnoses even when patients present with vague symptoms. Regular follow-ups during anticancer therapies could be crucial in effectively managing side effects such as dizziness.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Improved symptoms
393 people found this helpful
For years, I suffered from face flushing, anxiety, sleeplessness, fatigue, and dizziness. After researching magnesium deficiency, which I discussed with my doctor, I found this vitamin. After a couple of weeks, I noticed a reduction in my issues, and after a month, I felt much better. I no longer take medications and feel remarkable. This supplement has been transformative for me over the past three years.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Komoda J, Hori T, Sato K, Kusajima K, Shimizu T. Hypomagnesemia because of nedaplatin for cervical cancer: A case report. J Gen Fam Med. 2023;24:257. doi:10.1002/jgf2.630
- Chua KW, Huang X, Koh XH, Soh JFJY, Barrera VC, et al. Randomized Controlled Trial Assessing Vitamin D's Role in Reducing BPPV Recurrence in Older Adults. Otolaryngol Head Neck Surg. 2025;172:127. doi:10.1002/ohn.954
- Libonati GA, Leone A, Martellucci S, Gallo A, Albera R, et al. Prevention of Recurrent Benign Paroxysmal Positional Vertigo: The Role of Combined Supplementation with Vitamin D and Antioxidants. Audiol Res. 2022;12:445. doi:10.3390/audiolres12040045
- Gu X, Dong F, Gu J. Analysis of effect of 1α-hydroxyvitamin D3 on benign paroxysmal positional vertigo and risk factors. Exp Ther Med. 2018;15:2321. doi:10.3892/etm.2018.5699
- Sheikhzadeh M, Lotfi Y, Mousavi A, Heidari B, Bakhshi E. The effect of serum vitamin D normalization in preventing recurrences of benign paroxysmal positional vertigo: A case-control study. Caspian J Intern Med. 2016;7:173.
- Sheikhzadeh M, Lotfi Y, Mousavi A, Heidari B, Monadi M, et al. Influence of supplemental vitamin D on intensity of benign paroxysmal positional vertigo: A longitudinal clinical study. Caspian J Intern Med. 2016;7:93.
- Talaat HS, Kabel AM, Khaliel LH, Abuhadied G, El-Naga HA, et al. Reduction of recurrence rate of benign paroxysmal positional vertigo by treatment of severe vitamin D deficiency. Auris Nasus Larynx. 2016;43:237. doi:10.1016/j.anl.2015.08.009
- Mori K, Niimura S, Mizuno K. [A case of idiopathic hypoparathyroidism complicated with chronic thyroiditis]. Nihon Naibunpi Gakkai Zasshi. 1991;67:1339.
- Qiao Y, Zhao J, Wu J, Cao L, Song G, et al. Clinical and genetic analysis of a case of Gitelman syndrome accompanied with Graves disease and adrenocortical adenoma: A case report. Medicine (Baltimore). 2024;103:e37770. doi:10.1097/MD.0000000000037770
- Hannigan IP, Rosengren SM, Di Tanna GL, Watson SRD, Welgampola MS. Effects of nonprescription therapies on vestibular migraine: a questionnaire-based observational study. Intern Med J. 2024;54:916. doi:10.1111/imj.16314
- Pawar V, Ashraf H, Dorsala S, Mary P, Hameed N, et al. Motorist's Vestibular Disorientation Syndrome (MVDS)-Proposed Diagnostic Criteria. J Pers Med. 2023;13. doi:10.3390/jpm13050732
- Viola P, Marcelli V, Sculco D, Pisani D, Caglioti A, et al. Vestibular Disorders after Kidney Transplantation: Focus on the Pathophysiological Mechanisms Underlying the Vertical Nystagmus Associated with Tacrolimus-Related Hypomagnesamia. Int J Environ Res Public Health. 2022;19. doi:10.3390/ijerph19042260
- Abouzari M, Abiri A, Djalilian HR. Successful treatment of a child with definite Meniere's disease with the migraine regimen. Am J Otolaryngol. 2019;40:440. doi:10.1016/j.amjoto.2019.02.004
- Moshtaghi O, Mahboubi H, Haidar YM, Sahyouni R, Lin HW, et al. Resolution of Persistent Post-Stapedotomy Vertigo With Migraine Prophylactic Medication. Otol Neurotol. 2017;38:1500. doi:10.1097/MAO.0000000000001596
- Sun CY, Wu SH, Chao CT, Lin SH. Recurrent falls as the presentations of Gitelman syndrome in an octogenarian. Aging (Albany NY). 2025;null. doi:10.18632/aging.206216
