' 
SCIENTIFIC SCORE
Possibly Effective
Based on 29 Researches
7.6
USERS' SCORE
Good
Based on 31 Reviews
8.9
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Iron (as ferrous sulfate)
65 mg
361%
Top Medical Research Studies
9.5
Iron treatment reduces anemia
Iron deficiency and anemia in pregnancy: a call to action!: -"If you don't take a temperature, you can't find a fever".
Focused study on anemia treatment
We examined how iron treatment specifically impacts anemia, particularly during pregnancy. Iron deficiency is a leading cause of anemia, and finding the right treatment is crucial for both mothers and their developing babies.
Our study focused on just the effects of iron without looking at other treatments. This clear approach allowed us to isolate the benefits of iron supplementation. The results were insightful, showing that iron treatment had measurable effects on reducing anemia.
However, we must be careful about overgeneralizing these findings. While our results indicate improvements, it's important to recognize that individual responses to iron may vary. Our findings highlight the importance of monitoring iron levels in pregnant women to effectively address anemia.
Our study focused on just the effects of iron without looking at other treatments. This clear approach allowed us to isolate the benefits of iron supplementation. The results were insightful, showing that iron treatment had measurable effects on reducing anemia.
However, we must be careful about overgeneralizing these findings. While our results indicate improvements, it's important to recognize that individual responses to iron may vary. Our findings highlight the importance of monitoring iron levels in pregnant women to effectively address anemia.
Read More
8
Iron treatment and CKD anemia
Iron in Chronic Kidney Disease and End-Stage Kidney Disease-Current Trends and Future Direction.
Strong relevance to kidney disease
We explored the critical relationship between iron treatment and anemia in chronic kidney disease (CKD). Anemia often arises in CKD patients, whether they are on dialysis or not, primarily due to erythropoietin deficiency. However, iron deficiency plays a significant role and can be categorized into absolute, caused by blood loss, or functional, which is affected by inflammation and high levels of hepcidin.
Hepcidin impedes the body’s ability to use iron effectively, trapping it where it's not accessible for red blood cell production. This disruption in iron metabolism also means that oral iron supplements may not work well, especially in advanced CKD. Therefore, we reviewed various intravenous (IV) iron formulations available for treatment and outlined the diagnostic criteria and treatment benchmarks for iron deficiency in CKD patients.
Our findings led us to consider future therapeutic directions to improve patient outcomes. With advancements in the understanding of iron’s role in this context, the hope is to enhance treatment strategies for managing anemia in CKD effectively.
Hepcidin impedes the body’s ability to use iron effectively, trapping it where it's not accessible for red blood cell production. This disruption in iron metabolism also means that oral iron supplements may not work well, especially in advanced CKD. Therefore, we reviewed various intravenous (IV) iron formulations available for treatment and outlined the diagnostic criteria and treatment benchmarks for iron deficiency in CKD patients.
Our findings led us to consider future therapeutic directions to improve patient outcomes. With advancements in the understanding of iron’s role in this context, the hope is to enhance treatment strategies for managing anemia in CKD effectively.
Read More
8
Ferric Carboxymaltose Replaces Iron Sucrose
A cost-effective innovation in anaemia management for paediatric patients with haemodialysis-dependent chronic kidney disease.
High relevance to pediatric anemia
We aimed to find a better way to manage anemia in pediatric patients undergoing hemodialysis. Traditionally, these patients receive intravenous (IV) iron therapy using iron sucrose, which requires frequent treatments and carries a risk of allergic reactions. Moving forward with a home hemodialysis program, we investigated ferric carboxymaltose as a safer and more effective alternative.
In our study, we looked closely at how ferric carboxymaltose performed in maintaining healthy levels of hemoglobin, transferrin saturation, and reticulocyte hemoglobin content over a 12-month period. We also compared its efficacy against traditional iron sucrose treatments. The results were encouraging, showing that ferric carboxymaltose not only matched the effectiveness of iron sucrose but also required fewer hospital visits, significantly easing the treatment burden on families.
Overall, our findings suggest that ferric carboxymaltose is both clinically effective and cost-efficient. By reducing the frequency of administration, this approach can enhance the quality of life for pediatric patients with anemia due to chronic kidney disease who depend on hemodialysis. We believe this innovation presents a promising shift in anemia management for this vulnerable population.
In our study, we looked closely at how ferric carboxymaltose performed in maintaining healthy levels of hemoglobin, transferrin saturation, and reticulocyte hemoglobin content over a 12-month period. We also compared its efficacy against traditional iron sucrose treatments. The results were encouraging, showing that ferric carboxymaltose not only matched the effectiveness of iron sucrose but also required fewer hospital visits, significantly easing the treatment burden on families.
Overall, our findings suggest that ferric carboxymaltose is both clinically effective and cost-efficient. By reducing the frequency of administration, this approach can enhance the quality of life for pediatric patients with anemia due to chronic kidney disease who depend on hemodialysis. We believe this innovation presents a promising shift in anemia management for this vulnerable population.
Read More
Most Useful Reviews
9.5
Best brand found
I had been dealing with chronic, sometimes severe anaemia and tried various prescription supplements that caused nausea. Eventually, I discovered these Nature Made iron supplements, which have no side effects. After sufficient time, I no longer feel the effects of anaemia, and my lab results often show normal ranges. I've found that taking one pill every other day maintains my health effectively. If others have not worked for you or made you feel ill, consider giving this brand a try.
Read More
9.5
Cured pica disorder
Helped with my pica disorder! I am so pleased I decided to start taking iron. I chose this specific supplement because I already occasionally use their melatonin pills. This iron has been incredibly beneficial. After my first pregnancy, I developed a strong urge to consume uncooked rice daily, which has had detrimental effects on my health. Through research, I discovered that I have a condition known as pica, often linked to iron deficiency/anemia. I have been close to anaemic but didn't receive a prescription from my doctor. However, after taking this iron for a week, the desire to eat rice has completely vanished! I'm ecstatic to share this change in my life, as it feels monumental. If you experience similar issues, please consult your doctor before trying this.
Read More
9.5
Stable anemia
Very effective! I have slight anaemia and an iron supplement was recommended by our family doctor a few years ago. I have used them with good results, and my anaemia has improved and is stable. I would recommend them to anyone needing a boost of iron.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 29 Researches
7.6
- All Researches
9.5
Iron treatment reduces anemia
Iron deficiency and anemia in pregnancy: a call to action!: -"If you don't take a temperature, you can't find a fever".
Focused study on anemia treatment
We examined how iron treatment specifically impacts anemia, particularly during pregnancy. Iron deficiency is a leading cause of anemia, and finding the right treatment is crucial for both mothers and their developing babies.
Our study focused on just the effects of iron without looking at other treatments. This clear approach allowed us to isolate the benefits of iron supplementation. The results were insightful, showing that iron treatment had measurable effects on reducing anemia.
However, we must be careful about overgeneralizing these findings. While our results indicate improvements, it's important to recognize that individual responses to iron may vary. Our findings highlight the importance of monitoring iron levels in pregnant women to effectively address anemia.
Our study focused on just the effects of iron without looking at other treatments. This clear approach allowed us to isolate the benefits of iron supplementation. The results were insightful, showing that iron treatment had measurable effects on reducing anemia.
However, we must be careful about overgeneralizing these findings. While our results indicate improvements, it's important to recognize that individual responses to iron may vary. Our findings highlight the importance of monitoring iron levels in pregnant women to effectively address anemia.
Read More
9.5
Identifying and treating hookworm infection
Combined morphological and molecular approaches to the clinical diagnosis of Necator americanus infection: a case report.
High relevance for diagnosis
We explored the challenges of diagnosing hookworm infections, particularly in severe cases. By using both morphological and molecular methods, we successfully identified a 75-year-old woman suffering from anemia linked to the hookworm species, Necator americanus. After confirming the infection through various tests, we initiated treatment with albendazole. Following this, we observed a significant improvement in her condition, with both the hookworm and her anemia effectively resolved.
Read More
9
Iron supplementation effects on anemia
Childhood iron-folic acid supplementation in India for mild-to-moderate anaemia.
Addresses anemia treatment effectiveness
We explored the impact of iron and folic acid supplementation on children suffering from mild-to-moderate anemia in India. This study specifically aimed to assess how effective iron treatments are in improving overall hemoglobin levels and reducing anemia symptoms.
The research consisted of controlled trials where groups of children received iron supplements, while others did not. By comparing these groups, we aimed to determine if there was a significant difference in the rates of recovery from anemia.
While we hoped for positive outcomes from the supplementation, the findings showed mixed results. In some cases, we observed improvements in hemoglobin levels, but the overall effectiveness was not as pronounced as anticipated. It's essential to take these findings into account when considering future strategies for combating anemia in children.
Our analysis highlights that while iron supplementation is a crucial piece of the puzzle for treating anemia, it’s also clear that additional factors may play significant roles in achieving optimal health outcomes for affected children.
The research consisted of controlled trials where groups of children received iron supplements, while others did not. By comparing these groups, we aimed to determine if there was a significant difference in the rates of recovery from anemia.
While we hoped for positive outcomes from the supplementation, the findings showed mixed results. In some cases, we observed improvements in hemoglobin levels, but the overall effectiveness was not as pronounced as anticipated. It's essential to take these findings into account when considering future strategies for combating anemia in children.
Our analysis highlights that while iron supplementation is a crucial piece of the puzzle for treating anemia, it’s also clear that additional factors may play significant roles in achieving optimal health outcomes for affected children.
Read More
9
Serum hepcidin aids anemia diagnosis
Serum hepcidin level with iron profile assay might replace bone marrow iron study as a diagnostic tool for evaluation of anemia in elderly without chronic renal disease.
Addresses anemia in elderly patients
We explored the effectiveness of serum hepcidin levels in diagnosing types of anemia in elderly patients, specifically focusing on iron deficiency anemia (IDA) and anemia of chronic disease (ACD). By studying a group of 100 elderly patients alongside 15 healthy controls, we aimed to find a less invasive way to distinguish between these two common conditions.
Through our evaluation, we observed significant differences in iron levels and hepcidin concentrations between patients with IDA and those with ACD. We discovered that serum hepcidin could effectively differentiate between the two types of anemia, boasting a remarkable sensitivity of 93.9% and a specificity of 92.2%. This points to hepcidin as a promising alternative to the traditional bone marrow iron study.
Interestingly, while hepcidin is a valuable marker, relying solely on it can lead to misdiagnoses, similar concerns arise with ferritin levels. Our findings suggest that combining hepcidin with the iron profile provides a more accurate assessment and could potentially replace more invasive diagnostic methods for anemia in the elderly. Overall, we find this combined approach to be a vital step forward in understanding and treating anemia related to iron levels.
Through our evaluation, we observed significant differences in iron levels and hepcidin concentrations between patients with IDA and those with ACD. We discovered that serum hepcidin could effectively differentiate between the two types of anemia, boasting a remarkable sensitivity of 93.9% and a specificity of 92.2%. This points to hepcidin as a promising alternative to the traditional bone marrow iron study.
Interestingly, while hepcidin is a valuable marker, relying solely on it can lead to misdiagnoses, similar concerns arise with ferritin levels. Our findings suggest that combining hepcidin with the iron profile provides a more accurate assessment and could potentially replace more invasive diagnostic methods for anemia in the elderly. Overall, we find this combined approach to be a vital step forward in understanding and treating anemia related to iron levels.
Read More
9
Roxadustat and iron enhance anemia
Study on HIF-PHI combined with iron supplement in treatment of renal anemia in rats.
High relevance to anemia treatment
We investigated the combination of Roxadustat, a newer treatment for anemia related to chronic kidney disease (CKD), alongside polysaccharide-iron complex (PIC) in rats. By dividing them into different groups, we observed how various doses of iron impacted hemoglobin levels and kidney function. The results showed that this combination significantly improved hemoglobin levels and kidney health. Importantly, adequate iron supply early on was crucial for effective anemia treatment. Combining these therapies appears beneficial in addressing anemia in CKD effectively.
Read More
User Reviews
USERS' SCORE
Good
Based on 31 Reviews
8.9
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Best brand found
I had been dealing with chronic, sometimes severe anaemia and tried various prescription supplements that caused nausea. Eventually, I discovered these Nature Made iron supplements, which have no side effects. After sufficient time, I no longer feel the effects of anaemia, and my lab results often show normal ranges. I've found that taking one pill every other day maintains my health effectively. If others have not worked for you or made you feel ill, consider giving this brand a try.
Read More
9.5
Cured pica disorder
Helped with my pica disorder! I am so pleased I decided to start taking iron. I chose this specific supplement because I already occasionally use their melatonin pills. This iron has been incredibly beneficial. After my first pregnancy, I developed a strong urge to consume uncooked rice daily, which has had detrimental effects on my health. Through research, I discovered that I have a condition known as pica, often linked to iron deficiency/anemia. I have been close to anaemic but didn't receive a prescription from my doctor. However, after taking this iron for a week, the desire to eat rice has completely vanished! I'm ecstatic to share this change in my life, as it feels monumental. If you experience similar issues, please consult your doctor before trying this.
Read More
9.5
Stable anemia
Very effective! I have slight anaemia and an iron supplement was recommended by our family doctor a few years ago. I have used them with good results, and my anaemia has improved and is stable. I would recommend them to anyone needing a boost of iron.
10
Lifesaver supplement
This has worked wonders for me. I struggled with my anaemia, which caused prolonged bleeding for over 90 days. After I started taking this supplement, I have stopped bleeding and no longer feel exhausted. It's truly a lifesaver. If you need iron support, I highly recommend this!
8.8
Improved appetite
Those with anemia and poor appetite can benefit from this product. I had anemia, hair loss, and fatigue, but after using it, I felt much better. The key is to continue taking it without experiencing constipation like other iron supplements.
