Nanoparticulate MgH ameliorates anxiety/depression-like behaviors in a mouse model of multiple sclerosis by regulating microglial polarization and oxidative stress.
We aimed to understand the impact of nanoparticulate magnesium hydride (MgH) on anxiety and depression associated with multiple sclerosis (MS). Our exploration involved studying how MgH affects mood disorders in a model we designed, specifically using experimental autoimmune encephalomyelitis (EAE) mice.
We discovered that MgH treatment significantly alleviated anxiety and depression-like behaviors in these mice. Not only did MgH help improve their mood, but it also reduced overall disease severity and inflammatory damage within the central nervous system.
Importantly, our findings suggest that MgH could be working by promoting healthier microglial activity. It appears to encourage the beneficial M2 polarization while inhibiting the harmful M1 polarization, alongside reducing oxidative stress. This mechanism offers a glimpse into how magnesium might truly enhance well-being for those dealing with MS-related psychiatric issues.
In summary, our research indicates that nanoparticulate MgH holds promise as a non-toxic and effective treatment option for anxiety and depression in people suffering from MS, showcasing a potential breakthrough in managing these debilitating conditions.
Read More
7
Magnesium affects anxiety via gut bacteria
Magnesium Oxide Reduces Anxiety-like Behavior in Mice by Inhibiting Sulfate-Reducing Bacteria.
We examined the link between magnesium oxide and anxiety-like behavior in mice. The research focused on how a specific type of bacteria in the gut, known as sulfate-reducing bacteria (SRB), might contribute to anxiety. When we introduced these bacteria into the mice, they exhibited increased signs of anxiety, which we measured using a test called the open field test.
Next, we explored the effect of magnesium oxide on the growth of these bacteria in both lab settings and in real-life scenarios involving psychological stress, specifically using a water avoidance stress model. Remarkably, we found that magnesium oxide effectively inhibited the growth of SRB and the production of a byproduct called hydrogen sulfide in a dose-dependent manner.
Mice subjected to stress developed an overgrowth of SRB and displayed amplified anxiety-like behavior. However, those fed a magnesium oxide-enriched diet showed reduced levels of both SRB and anxiety. Our findings suggest that magnesium may play a significant role in mitigating anxiety by altering gut bacteria dynamics.
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5
Magnesium's effects on anxiety examined
The effect of magnesium sulfate on memory and anxiety-like behavior in a rat model: an investigation of its neuronal molecular mechanisms.
We investigated how magnesium sulfate affects anxiety-like behaviors and memory in male rats suffering from induced anxiety through exposure to predator odor. By using a series of behavioral tests alongside a comparison to diazepam—an established anxiolytic medication—we aimed to assess the potential benefits of magnesium treatment in managing anxiety.
Our findings revealed that magnesium did provide some anxiolytic effects, but it fell short compared to diazepam, especially regarding its impact on anxiety. Interestingly, we noticed that the response to magnesium varied depending on the dosage used. In addition to these behavioral observations, we also examined changes in oxidative stress and nitric oxide levels in the brain, suggesting that magnesium treatment has the potential to counteract increased oxidative stress that comes with anxiety.
This research adds to the understanding of magnesium's role in anxiety management, highlighting its ability to modulate oxidative stress, although further studies will be required to fully grasp its effects and optimize its application in anxiety disorders.
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Most Useful Reviews
9
Holy grail supplement
336 people found this helpful
I rarely write reviews, but this supplement is incredible! I’ve tried various magnesium products, but this is by far the best. I take two capsules before bed, and my anxiety and stress levels have significantly decreased, allowing me to fall asleep easily and wake up refreshed. It has also relieved my muscle cramps due to stress. GREAT PRODUCT!
Read More
9
Effective for sleep
13 people found this helpful
I purchased this for anxiety and sleep issues, initially sceptical about its effectiveness. However, it works! After adjusting my timing, I finally got more than a few hours of sleep. I noticed a reduction in anxiety but had to stop taking it due to vertigo after its formula changed. I would not recommend it now, as I experienced significant dizziness when I resumed taking it due to the new ingredients.
Read More
9
Stabilised mood
9 people found this helpful
I tried magnesium glycinate after previous forms didn't work. It significantly reduced my calf cramps and stabilised my mood, making me feel calmer. I also noticed great results for a young athlete I know, aiding in recovery and muscle endurance.
We examined how magnesium, in combination with ibogaine, affects anxiety in veterans with traumatic brain injuries. This was part of a larger study focusing on the wellbeing of Special Operations Forces veterans, who often suffer from mental health issues like anxiety and PTSD after experiencing head trauma.
The study involved 30 male veterans, primarily with mild brain injuries. Researchers used various assessments, including scales for anxiety, to measure changes before treatment and then again one month afterward. The findings were promising, showing considerable improvements in anxiety levels, as well as in depression and PTSD symptoms.
However, it’s important to note that since magnesium was administered alongside ibogaine, we can’t isolate the effects of magnesium alone on anxiety. Although the results were encouraging, we need more controlled clinical trials to fully understand the safety and effectiveness of magnesium treatment on its own.
Overall, while magnesium may play a role in improving anxiety, further research is essential to clarify its specific impact without the influence of other treatments.
Read More
8
Magnesium's role in anxiety treatment
Efficacy of Magnesium Sulfate and Labetalol in the Treatment of Pregnancy-Induced Hypertension and Its Effect on Anxiety and Depression: A Retrospective Cohort Study.
We explored the effects of magnesium sulfate and labetalol on managing pregnancy-induced hypertension (PIH) and their potential influence on anxiety and depression among patients. In our study, we examined data from patients diagnosed with PIH from July 2020 to July 2023 at two hospitals in Chengdu, China.
Among the 219 participants, we found that 36.1% experienced anxiety and depression. We divided patients into two groups based on treatment: one group received magnesium sulfate and labetalol, while the other group received standard treatment. It was notable that those in the magnesium sulfate and labetalol group reported significant improvements in anxiety and depression levels, as measured by the Edinburgh Postnatal Depression Scale and the Generalized Anxiety Disorder 7 scale.
However, when evaluating blood pressure control, the effectiveness was similar across both groups, which means the treatment did not significantly impact blood pressure outcomes. Overall, this research points to the possibility that magnesium sulfate and labetalol can not only help manage high blood pressure in pregnant women but may also indirectly alleviate feelings of anxiety and depression.
Read More
8
Magnesium aids post-surgery anxiety
Effects of intravenous single-bolus lidocaine infusion versus intravenous single-bolus magnesium sulfate infusion on postoperative pain, emotional status, and quality of life in patients undergoing spine fusion surgery: a randomized study.
This study set out to understand how magnesium, combined with lidocaine, influences anxiety levels and postoperative pain in patients undergoing spine fusion surgery. We engaged 120 patients aged 18 to 60 and divided them into different groups, each receiving varying treatments, including a control group that received saline.
Importantly, we observed that the group receiving the combination of lidocaine and magnesium experienced lower anxiety and depression levels following surgery. Not only did this treatment seem to help in managing pain more effectively, but it also enhanced overall patient satisfaction three months after a single infusion.
While the study highlighted the synergistic effects of combining both medications, the specific impact of magnesium alone on anxiety isn't entirely clear. The results suggested that while magnesium played a role within the combination treatment, isolating its effect on anxiety wasn't feasible in this context.
Nonetheless, the findings are promising for those seeking alternatives to standard pain management that could include anxiety relief in the postoperative period. It opens up avenues for further research on magnesium’s individual role in emotional health.
Read More
8
Magnesium reduces anxiety symptoms
Neuroprotective effects of magnesium against stress induced by hydrogen peroxide in Wistar rat.
We investigated how magnesium might influence anxiety, particularly when triggered by oxidative stress from hydrogen peroxide. The study involved eighteen Wistar rats divided into three groups: a control group, a group treated with hydrogen peroxide, and a group receiving both hydrogen peroxide and magnesium sulphate.
Our findings revealed that the rats exposed to hydrogen peroxide exhibited increased anxiety and signs of oxidative damage in the brain. However, those that received magnesium showed significant improvements. They not only had reduced levels of anxiety but also demonstrated less oxidative stress.
This suggests that magnesium could play a beneficial role in counteracting anxiety and the negative effects of oxidative stress. Though the results are promising, it's important to remember that further research is needed to fully understand magnesium's potential effects on anxiety in humans.
Read More
8
Magnesium treats anxiety in MS
Nanoparticulate MgH ameliorates anxiety/depression-like behaviors in a mouse model of multiple sclerosis by regulating microglial polarization and oxidative stress.
We aimed to understand the impact of nanoparticulate magnesium hydride (MgH) on anxiety and depression associated with multiple sclerosis (MS). Our exploration involved studying how MgH affects mood disorders in a model we designed, specifically using experimental autoimmune encephalomyelitis (EAE) mice.
We discovered that MgH treatment significantly alleviated anxiety and depression-like behaviors in these mice. Not only did MgH help improve their mood, but it also reduced overall disease severity and inflammatory damage within the central nervous system.
Importantly, our findings suggest that MgH could be working by promoting healthier microglial activity. It appears to encourage the beneficial M2 polarization while inhibiting the harmful M1 polarization, alongside reducing oxidative stress. This mechanism offers a glimpse into how magnesium might truly enhance well-being for those dealing with MS-related psychiatric issues.
In summary, our research indicates that nanoparticulate MgH holds promise as a non-toxic and effective treatment option for anxiety and depression in people suffering from MS, showcasing a potential breakthrough in managing these debilitating conditions.
I rarely write reviews, but this supplement is incredible! I’ve tried various magnesium products, but this is by far the best. I take two capsules before bed, and my anxiety and stress levels have significantly decreased, allowing me to fall asleep easily and wake up refreshed. It has also relieved my muscle cramps due to stress. GREAT PRODUCT!
Read More
9
Effective for sleep
13 people found this helpful
I purchased this for anxiety and sleep issues, initially sceptical about its effectiveness. However, it works! After adjusting my timing, I finally got more than a few hours of sleep. I noticed a reduction in anxiety but had to stop taking it due to vertigo after its formula changed. I would not recommend it now, as I experienced significant dizziness when I resumed taking it due to the new ingredients.
Read More
9
Stabilised mood
9 people found this helpful
I tried magnesium glycinate after previous forms didn't work. It significantly reduced my calf cramps and stabilised my mood, making me feel calmer. I also noticed great results for a young athlete I know, aiding in recovery and muscle endurance.
Read More
9
Calms nervous system
7 people found this helpful
Magnesium is essential for wellbeing. I regularly use this magnesium formulation, which comes with beneficial plant supplements. It effectively alleviates anxiety symptoms and promotes restful sleep. I highly recommend it for those struggling with thyroid issues.
Read More
9
Fights anxiety symptoms
6 people found this helpful
I started taking magnesium after experiencing anxiety symptoms like rapid heartbeat and insomnia. After a month, I noticed significant improvement; I feel calmer and no longer suffer from insomnia. The good absorption of this magnesium makes it a reliable choice.
Anxiety is a natural and often healthy emotion characterized by feelings of worry, nervousness, or fear about an impending event or situation. While some level of anxiety is a normal reaction to stress, excessive or chronic anxiety can become a mental health issue. It may present in various forms, from everyday worries to more severe conditions such as generalized anxiety disorder (GAD), panic disorder, or social anxiety disorder. Symptoms can manifest both psychologically, such as persistent worry and difficulty concentrating, and physically, including symptoms like increased heart rate, sweating, or fatigue.
Understanding the difference between normal anxiety and an anxiety disorder is crucial. Normal anxiety can be beneficial, motivating you to prepare for important events like exams or public speaking. However, when it starts to interfere with daily activities or leads to avoidance behaviors, it may indicate the need for professional help. Treatments for anxiety often include therapy, medications, and lifestyle changes, allowing individuals to manage their symptoms effectively. If someone is struggling with anxiety that impacts their quality of life, seeking guidance from a healthcare professional is a key step toward recovery.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
Magnesium has been studied for its potential role in alleviating symptoms of anxiety, and some evidence suggests it may be beneficial. Magnesium plays a critical role in brain function and the regulation of neurotransmitters, which are essential for mood stability. Some studies have indicated that low levels of magnesium may be linked to increased anxiety symptoms, and supplementation could work to help improve overall mental health by restoring adequate magnesium levels. While it's not a standalone treatment for anxiety disorders, integrating magnesium into a balanced diet with other treatment modalities could provide additional support.
That said, it's important to approach magnesium supplementation thoughtfully. Overuse can lead to adverse effects, and individual needs may vary widely depending on dietary intake and overall health status. Before starting any new supplement, especially for managing anxiety, consulting with a healthcare professional is advisable to tailor an approach that aligns with your personal health needs. In summary, while magnesium can play a role in supporting anxiety management, it should complement traditional treatments rather than serve as a primary solution.
Based on user reviews, the time it takes to see results from magnesium glycinate can vary, but many users report noticeable improvements within a week to a month. For instance, one user mentioned experiencing significant improvements after just one week of use, particularly in managing their anxiety during stressful times Read Review. In contrast, another user noted a marked reduction in anxiety after two weeks, highlighting the product's high quality and absorption Read Review.
Some users have also reported quicker responses, with one noticing a calming effect after just three days Read Review. It's important to note that individual experiences may differ; while some may feel effects sooner, others may require more time for the supplement to work effectively in alleviating anxiety symptoms. Ultimately, those considering magnesium glycinate for anxiety should be open to a range of timelines while monitoring their own responses to the supplement.
Research suggests that magnesium may have potential benefits for managing anxiety, though findings are mixed and often require more rigorous investigation. Various studies indicate that magnesium supplementation can lead to reductions in anxiety levels, particularly in specific populations or under certain conditions. For instance, a systematic review identified improvements in self-reported anxiety levels from a variety of studies, indicating that magnesium could be useful for those with mild anxiety, especially if they have low magnesium levels to begin with [3]. Additionally, a study involving magnesium sulfate showed significant improvements in anxiety among patients during pregnancy [4].
However, the effects of magnesium on anxiety are not universally strong and can depend on individual circumstances. Some studies found promising results where magnesium treatments led to reduced anxiety in animal models [10] or during specific therapies [5]. Yet, it's important to note that many of the studies varied in their methodologies and populations, which complicates the ability to draw definitive conclusions. In summary, while there is some scientific support for magnesium's role in alleviating anxiety, more extensive and focused trials are necessary to confirm its efficacy and clarify optimal dosages and contexts for use.
Based on user reviews, many individuals have reported significant improvements in various symptoms related to anxiety, sleep disorders, and even muscle cramps after using magnesium glycinate. For example, one user mentioned that it not only helped stabilize their mood but also effectively reduced calf cramps, which is a common complaint for athletes Read Review. A notable number of reviewers highlighted enhanced sleep quality, with one user claiming they no longer suffer from insomnia after a month of use, feeling calmer overall Read Review.
Additionally, a few users experienced rapid improvement in anxiety levels or sleep disruptions after just a few days of supplementing with magnesium glycinate. For instance, one user reported feeling a calming effect within three days Read Review. Moreover, another user experienced effective anxiety management and improved general wellbeing after transitioning off beta blockers Read Review. It's crucial to keep in mind that while many users reported positive outcomes, individual results can differ significantly; some may find magnesium glycinate more beneficial than others, and the time taken to see changes can vary widely.
Based on user reviews, many individuals have reported positive experiences when combining magnesium glycinate with other supplements for managing anxiety. For instance, one user noted that alongside vitamin B6, they observed a reduction in anxiety symptoms and improvements in their menstrual cycle Read Review. Another reviewer mentioned that using magnesium glycinate in conjunction with essential oils dramatically improved their anxiety levels, allowing them to transition off beta blockers smoothly Read Review. These anecdotes suggest that multi-supplement approaches can enhance the efficacy of magnesium glycinate for anxiety relief.
However, not every combination appears to be effective; one user reported a negative reaction, stating their anxiety and insomnia increased after starting magnesium glycinate, indicating that individual reactions can vary Read Review. Overall, while many users advocate for the benefits of magnesium glycinate in managing anxiety alongside other supplements, it's essential for individuals to observe their own responses carefully and consult healthcare professionals when considering supplement combinations.
Based on user reviews, many individuals have found magnesium glycinate to be effective for managing anxiety, with suggested dosages varying. Some users report taking between 800 to 1000 mg daily, noting significant improvements in anxiety symptoms and overall mood stability. For instance, one user mentioned taking 2 capsules and experiencing a clearer head and calmness during stressful times, while another preferred a smaller dose of 2 capsules at night, experiencing relief from anxiety and improved sleep Read ReviewRead Review.
The absorption quality of magnesium glycinate seems to be a key factor for users, as several highlighted that it is well-absorbed and gentle on the stomach. This makes it suitable for those who are sensitive to other forms of magnesium that may cause gastrointestinal discomfort. Users have noted that the calming effects manifest relatively quickly, with some mentioning improvements within a few days to weeks of consistent use Read ReviewRead Review. Overall, while individual experiences may vary, magnesium glycinate appears to be a popular choice for anxiety management, and many users recommend it based on their positive results.
8
Reduces anxiety significantly
2 people found this helpful
In search of good magnesium, I found these vitamins with glycinate, which is highly bioavailable and helps soothe the nervous system. It assists with issues like insomnia and anxiety without causing bowel movements. The capsules are large, but easy to swallow. They greatly assisted my family during stressful times; noticeable improvements occurred within a week.
9
Effective anxiety relief
This magnesium is excellent! After two weeks, I noticed a marked decrease in anxiety, and falling asleep became easier. While the price is high, I find the quality and absorption impressive. I will use it in cycles to maintain its effects.
9
Eases anxiety quickly
1 people found this helpful
This is the best magnesium I’ve tried; it quickly alleviated my anxiety during a stressful time. I took 2 capsules and felt clearer-headed and calmer, unlike other brands that required multiple doses. The quality and packaging are excellent, making it easy to swallow.
9
Stabilised mood
9 people found this helpful
I tried magnesium glycinate after previous forms didn't work. It significantly reduced my calf cramps and stabilised my mood, making me feel calmer. I also noticed great results for a young athlete I know, aiding in recovery and muscle endurance.
9
Fights anxiety symptoms
6 people found this helpful
I started taking magnesium after experiencing anxiety symptoms like rapid heartbeat and insomnia. After a month, I noticed significant improvement; I feel calmer and no longer suffer from insomnia. The good absorption of this magnesium makes it a reliable choice.
9
Significant anxiety improvement
2 people found this helpful
After years in a continuous state of panic, magnesium glycinate, alongside essential oils, markedly improved my anxiety levels. I transitioned off beta blockers within days and now manage my anxiety effectively on a lower scale.
7.5
Alleviates anxiety issues
1 people found this helpful
This magnesium is the best I've found online. It doesn't affect my gastrointestinal system. After feeling anxious and experiencing cramps post-COVID, I took 2 capsules and along with vitamin B6, I noticed a reduction in anxiety and improvements in my menstrual cycle. Although expensive, it works effectively for me.
1
Negative anxiety response
2 people found this helpful
After three days, this product caused a negative reaction, increasing my anxiety and insomnia. It’s not worth the high price.
9
Supports mental health
1 people found this helpful
Magnesium glycinate significantly calms me during periods of stress. It works well for sleep disorders, anxiety, and muscle spasms. I take 800-1000 mg daily, feeling much better as it aids my nervous system. The quality is good, and the convenient packaging is a plus.
9
Comfortable digestion
3 people found this helpful
Magnesium is essential, yet many experience deficiency. I take two capsules nightly; it's well absorbed and effectively tackles anxiety. Recommended purchase!
7
Magnesium shows potential for anxiety
Examining the Effects of Supplemental Magnesium on Self-Reported Anxiety and Sleep Quality: A Systematic Review.
We conducted a systematic review to evaluate how magnesium might help with anxiety. As self-treatment with supplements grows in popularity, we focused on the clinical evidence surrounding magnesium’s effects on anxiety and sleep disorders.
Through our thorough search, we found 15 studies that fit our strict criteria. Most of these studies showed at least some improvement in either anxiety levels or sleep quality. In fact, five out of eight studies looking at sleep-related outcomes noted positive changes, while five out of seven studies focused on anxiety reported improvements in self-reported anxiety.
Despite the encouraging findings, we have to approach these results with caution. The studies varied in terms of dosage, formulation, and duration of magnesium treatment. Plus, some included other active ingredients that make it hard to know magnesium’s exact impact. Interestingly, two of the studies that didn’t show improvement involved populations with other health concerns, highlighting the need for further investigation.
Overall, it seems like magnesium might be a useful supplement for those dealing with mild anxiety, especially if they have low magnesium levels to begin with. However, larger and more rigorous trials are essential to truly confirm its effectiveness and determine the best types and doses for use.
8
Magnesium's role in anxiety treatment
Efficacy of Magnesium Sulfate and Labetalol in the Treatment of Pregnancy-Induced Hypertension and Its Effect on Anxiety and Depression: A Retrospective Cohort Study.
We explored the effects of magnesium sulfate and labetalol on managing pregnancy-induced hypertension (PIH) and their potential influence on anxiety and depression among patients. In our study, we examined data from patients diagnosed with PIH from July 2020 to July 2023 at two hospitals in Chengdu, China.
Among the 219 participants, we found that 36.1% experienced anxiety and depression. We divided patients into two groups based on treatment: one group received magnesium sulfate and labetalol, while the other group received standard treatment. It was notable that those in the magnesium sulfate and labetalol group reported significant improvements in anxiety and depression levels, as measured by the Edinburgh Postnatal Depression Scale and the Generalized Anxiety Disorder 7 scale.
However, when evaluating blood pressure control, the effectiveness was similar across both groups, which means the treatment did not significantly impact blood pressure outcomes. Overall, this research points to the possibility that magnesium sulfate and labetalol can not only help manage high blood pressure in pregnant women but may also indirectly alleviate feelings of anxiety and depression.
8
Magnesium reduces anxiety symptoms
Neuroprotective effects of magnesium against stress induced by hydrogen peroxide in Wistar rat.
We investigated how magnesium might influence anxiety, particularly when triggered by oxidative stress from hydrogen peroxide. The study involved eighteen Wistar rats divided into three groups: a control group, a group treated with hydrogen peroxide, and a group receiving both hydrogen peroxide and magnesium sulphate.
Our findings revealed that the rats exposed to hydrogen peroxide exhibited increased anxiety and signs of oxidative damage in the brain. However, those that received magnesium showed significant improvements. They not only had reduced levels of anxiety but also demonstrated less oxidative stress.
This suggests that magnesium could play a beneficial role in counteracting anxiety and the negative effects of oxidative stress. Though the results are promising, it's important to remember that further research is needed to fully understand magnesium's potential effects on anxiety in humans.
8
Magnesium aids post-surgery anxiety
Effects of intravenous single-bolus lidocaine infusion versus intravenous single-bolus magnesium sulfate infusion on postoperative pain, emotional status, and quality of life in patients undergoing spine fusion surgery: a randomized study.
This study set out to understand how magnesium, combined with lidocaine, influences anxiety levels and postoperative pain in patients undergoing spine fusion surgery. We engaged 120 patients aged 18 to 60 and divided them into different groups, each receiving varying treatments, including a control group that received saline.
Importantly, we observed that the group receiving the combination of lidocaine and magnesium experienced lower anxiety and depression levels following surgery. Not only did this treatment seem to help in managing pain more effectively, but it also enhanced overall patient satisfaction three months after a single infusion.
While the study highlighted the synergistic effects of combining both medications, the specific impact of magnesium alone on anxiety isn't entirely clear. The results suggested that while magnesium played a role within the combination treatment, isolating its effect on anxiety wasn't feasible in this context.
Nonetheless, the findings are promising for those seeking alternatives to standard pain management that could include anxiety relief in the postoperative period. It opens up avenues for further research on magnesium’s individual role in emotional health.
References
Strodl E, Bambling M, Parnam S, Ritchie G, Cramb S, et al. Probiotics and magnesium orotate for the treatment of major depressive disorder: a randomised double blind controlled trial. Sci Rep. 2024;14:20841. 10.1038/s41598-024-71093-z
Coffman CN, Carroll-Portillo A, Alcock J, Singh SB, Rumsey K, et al. Magnesium Oxide Reduces Anxiety-like Behavior in Mice by Inhibiting Sulfate-Reducing Bacteria. Microorganisms. 2024;12. 10.3390/microorganisms12071429
Rawji A, Peltier MR, Mourtzanakis K, Awan S, Rana J, et al. Examining the Effects of Supplemental Magnesium on Self-Reported Anxiety and Sleep Quality: A Systematic Review. Cureus. 2024;16:e59317. 10.7759/cureus.59317
Wang S, Zhang J, Zhu T, Xie X, Xia X, et al. Efficacy of Magnesium Sulfate and Labetalol in the Treatment of Pregnancy-Induced Hypertension and Its Effect on Anxiety and Depression: A Retrospective Cohort Study. Alpha Psychiatry. 2024;25:243. 10.5152/alphapsychiatry.2024.231342
Abdel Rady MM, Osman AM, Abo Elfadl GM, Ahmed HM, Sayed S, et al. Effects of intravenous single-bolus lidocaine infusion versus intravenous single-bolus magnesium sulfate infusion on postoperative pain, emotional status, and quality of life in patients undergoing spine fusion surgery: a randomized study. Minerva Anestesiol. 2024;90:397. 10.23736/S0375-9393.24.17868-6
Cetin A, Ozdemir E, Golgeli A, Taskiran AS, Karabulut S, et al. The effect of magnesium sulfate on memory and anxiety-like behavior in a rat model: an investigation of its neuronal molecular mechanisms. Neurol Res. 2024;46:752. 10.1080/01616412.2024.2352234
Mititelu-Tartau L, Bogdan M, Pavel LL, Rezus C, Foia CI, et al. Anxiolytic-like Activity, Antioxidant Properties, and Facilitatory Effects on the Short-Term Memory Retention of Molsidomine in Rats. Life (Basel). 2024;14. 10.3390/life14030306
Cherian KN, Keynan JN, Anker L, Faerman A, Brown RE, et al. Magnesium-ibogaine therapy in veterans with traumatic brain injuries. Nat Med. 2024;30:373. 10.1038/s41591-023-02705-w
Pickering G, Noah L, Pereira B, Goubayon J, Leray V, et al. Assessing brain function in stressed healthy individuals following the use of a combination of green tea, Rhodiola, magnesium, and B vitamins: an fMRI study. Front Nutr. 2023;10:1211321. 10.3389/fnut.2023.1211321
Hajri L, Othman H, Ghodbane S, Sakly M, Abdelmelek H, et al. Neuroprotective effects of magnesium against stress induced by hydrogen peroxide in Wistar rat. Biomarkers. 2023;28:538. 10.1080/1354750X.2023.2246104
Li Z, Chen K, Shao Q, Lu H, Zhang X, et al. Nanoparticulate MgH ameliorates anxiety/depression-like behaviors in a mouse model of multiple sclerosis by regulating microglial polarization and oxidative stress. J Neuroinflammation. 2023;20:16. 10.1186/s12974-023-02696-y
Proskurnina EV, Liaukovich KM, Bychkovskaya LS, Mikheev IV, Alshanskaia EI, et al. Salivary Antioxidant Capacity and Magnesium in Generalized Anxiety Disorder. Metabolites. 2023;13. 10.3390/metabo13010073