'
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.5
USERS' SCORE
Good
Based on 1 Reviews
8.6
Supplement Facts
Serving Size:  1 Tablet
Serving Per Container:  275
Amount Per Serving
%DV
Total Carbohydrates
1 g
<1%**
Calcium (as Calcium Carbonate)
98 mg
8%
Proprietary BlendCascara Sagrada powder (bark), Fennel powder (seed), Psyllium powder (seed husk), Ginger powder (rhizome), Acacia Gum, Barley Grass powder (aerial), Beet powder (root), Glucomannan, Karaya Gum, Lemon Peel powder (peel), Oat Bran powder, Peppermint powder (leaf), Red Raspberry (Rubus idaeus) powder (leaf), Slippery Elm powder (bark), Chlorella powder, Guar Gum, Lactobacillus acidophilus (1 million/g *** )
542 mg

Top Medical Research Studies

9
Probiotics improve constipation symptoms
Impact of a probiotic chewable tablet on stool habits and microbial profile in children with functional constipation: A randomized controlled clinical trial.
High relevance to childhood constipation.
We conducted a randomized, placebo-controlled trial involving 92 children aged 4 to 12 with functional constipation. Over four weeks, we provided one group with a probiotic chewable tablet containing specific strains and compared their experiences to a placebo group.

The findings were promising; the probiotic group reported a significant improvement in stool frequency and a decrease in hard defecation. Specifically, hard stools decreased from 43% to 14%, while normal defecation increased from 56% to 80%. This study highlights the potential of probiotics as a valuable option for managing constipation in children.
Read More
8
Synbiotics improve constipation symptoms
The effects of synbiotics on indoxyl sulphate level, constipation, and quality of life associated with constipation in chronic haemodialysis patients: a randomized controlled trial.
Study relevance is well-grounded
We conducted a double-blinded, randomized controlled trial to explore the effects of synbiotics on constipation among chronic haemodialysis patients. While our study found that the synbiotic treatment did not significantly reduce indoxyl sulphate toxin levels, it notably improved constipation symptoms and the overall quality of life related to constipation.

This suggests that Lactobacillus acidophilus and Bifidobacterium longum may be beneficial for enhancing digestive comfort in individuals facing these challenges, even if they don't directly affect certain toxic levels in the body.
Read More
8
Probiotics improved bowel function post-surgery
Functional outcome, quality of life, and efficacy of probiotics in postoperative patients with colorectal cancer.
Study shows probiotic benefits
We evaluated how taking probiotics, specifically Lactobacillus acidophilus, could help improve bowel function and quality of life for patients after colorectal cancer surgery.

Using questionnaires sent to 193 patients, we found that those who took probiotics for three months reported better defecation frequency and less discomfort compared to those who did not.

Notably, all patients, regardless of their type of surgery, saw improvements in their bowel function and overall quality of life after the treatment.
Read More

Most Useful Reviews

9.5
Cleansing aid
Works well. First and foremost, don't take this if you're trying to lose weight—just exercise. If you're using this, it suggests you're in need of a colon cleanse or irregular bowel movement. I take this whenever I fly and have constipation; it truly helps.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.5
9.5
Lactobacillus improves IBS-C symptoms
Clinical assessment and cytokines level in constipation-predominant irritable bowel syndrome participants treated with Lactobacillus-containing cultured milk drink.
Consistent findings support treatment benefit
We investigated how a cultured milk drink containing Lactobacillus acidophilus affects symptoms of constipation in individuals with irritable bowel syndrome (IBS-C). Over 30 days, participants consumed the drink daily.

At the end of the study, an impressive 97.4% of IBS-C participants reported improvement in their constipation-related symptoms. We also noticed reductions in intestinal transit time and pro-inflammatory cytokines linked to IBS. Overall, this suggests that including this cultured milk drink may be a beneficial addition to IBS-C treatment plans.
Read More
9
Probiotics improve constipation symptoms
Impact of a probiotic chewable tablet on stool habits and microbial profile in children with functional constipation: A randomized controlled clinical trial.
High relevance to childhood constipation.
We conducted a randomized, placebo-controlled trial involving 92 children aged 4 to 12 with functional constipation. Over four weeks, we provided one group with a probiotic chewable tablet containing specific strains and compared their experiences to a placebo group.

The findings were promising; the probiotic group reported a significant improvement in stool frequency and a decrease in hard defecation. Specifically, hard stools decreased from 43% to 14%, while normal defecation increased from 56% to 80%. This study highlights the potential of probiotics as a valuable option for managing constipation in children.
Read More
9
Probiotics improve constipation symptoms
Effects of Fermented Milk with Mixed Strains as a Probiotic on the Inhibition of Loperamide-Induced Constipation.
Relevant for constipation treatment
We evaluated how lactobacillus acidophilus, both alone and in a mix with other bacteria, might relieve constipation caused by loperamide in rats. Over 14 days, we noticed that the groups receiving probiotics had significantly heavier and wetter stools compared to control animals.

Notably, the CKDBP group, a blend of multiple bacteria, showed the greatest improvement in intestinal transit. Measures like mucosal length and mucus secretion were also significantly enhanced in all probiotic-treated groups, highlighting their potential to alleviate constipation symptoms effectively.
Read More
8
Synbiotics improve constipation symptoms
The effects of synbiotics on indoxyl sulphate level, constipation, and quality of life associated with constipation in chronic haemodialysis patients: a randomized controlled trial.
Study relevance is well-grounded
We conducted a double-blinded, randomized controlled trial to explore the effects of synbiotics on constipation among chronic haemodialysis patients. While our study found that the synbiotic treatment did not significantly reduce indoxyl sulphate toxin levels, it notably improved constipation symptoms and the overall quality of life related to constipation.

This suggests that Lactobacillus acidophilus and Bifidobacterium longum may be beneficial for enhancing digestive comfort in individuals facing these challenges, even if they don't directly affect certain toxic levels in the body.
Read More
8
Probiotics ease constipation in patients
Randomized Clinical Trial: Probiotics Alleviated Oral-Gut Microbiota Dysbiosis and Thyroid Hormone Withdrawal-Related Complications in Thyroid Cancer Patients Before Radioiodine Therapy Following Thyroidectomy.
Moderate relevance to effectiveness
We investigated whether probiotics could ease complications like constipation in thyroid cancer patients undergoing thyroid hormone withdrawal. Fifty patients were randomly assigned to either probiotics or placebo during their treatment. The results showed that probiotics significantly reduced constipation alongside other symptoms, suggesting a positive impact on the gut and oral microbiota.

This improvement might be linked to the restoration of microbial diversity in these patients, highlighting the potential benefits of probiotics in managing constipation and other complications after thyroid surgery.
Read More

User Reviews

USERS' SCORE
Good
Based on 1 Reviews
8.6
9.5
Cleansing aid
Works well. First and foremost, don't take this if you're trying to lose weight—just exercise. If you're using this, it suggests you're in need of a colon cleanse or irregular bowel movement. I take this whenever I fly and have constipation; it truly helps.
image