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SCIENTIFIC SCORE
Questionable
Based on 7 Researches
6.9
USERS' SCORE
Good
Based on 5 Reviews
8.6
Supplement Facts
Serving Size: 2 Capsules
Amount Per Serving
%DV
European Elder (berry)
920 mg
**
European Elder (flower)
230 mg
**
Top Medical Research Studies
8
Elderberry protein's anticancer potential
Recombinant pebulin protein, a type 2 ribosome-inactivating protein isolated from dwarf elder (Sambucus ebulus L.) shows anticancer and antifungal activities in vitro.
Strong focus on cancer effects
We focused on a newly identified protein called pebulin, derived from dwarf elder, and examined its potential anticancer effects. The protein was successfully produced in E. coli and purified for further testing.
Our tests revealed that pebulin is not only capable of agglutinating red blood cells from all human blood types but also has significant inhibitory effects on cancer cell lines like MCF-7 and HT-29. This means that pebulin could slow down the growth of these cancer cells, a promising outcome we found particularly exciting.
Additionally, we noted that pebulin demonstrated effectiveness against certain plant fungi, showcasing its versatile bioactivity. The study suggests that pebulin may offer a new avenue for cancer treatment, particularly considering its impact on both cancer cells and fungi.
Our tests revealed that pebulin is not only capable of agglutinating red blood cells from all human blood types but also has significant inhibitory effects on cancer cell lines like MCF-7 and HT-29. This means that pebulin could slow down the growth of these cancer cells, a promising outcome we found particularly exciting.
Additionally, we noted that pebulin demonstrated effectiveness against certain plant fungi, showcasing its versatile bioactivity. The study suggests that pebulin may offer a new avenue for cancer treatment, particularly considering its impact on both cancer cells and fungi.
Read More
7
Elderberry extracts show cancer potential
flower and berry extracts for food and therapeutic applications: effect of gastrointestinal digestion on and bioactivity and toxicity.
Berry extracts effectiveness noted
We delved into how flower and berry extracts, with a focus on elderberry, affect cancer cells and assess their potential benefits in nutrition and therapy. The study investigated the behavior of these extracts before and after digestion to understand their bioavailability and effects on toxicity.
Upon analyzing the extracts, we found that the flower extract boasted a higher concentration of beneficial phenolic compounds compared to the berry extract. Importantly, when we tested how these extracts performed against cancerous cell lines, we noted variations in results. Both extracts reduced the formation of reactive oxygen species (ROS) in healthy cells under oxidative stress, with elderberry's effects being most pronounced in cancer cells.
The findings indicated a promising potential for these natural compounds, particularly elderberry, to be used in functional food formulations or as therapeutic agents against cancer. Thus, while the extracts generally showed a positive impact, further research is needed to fully understand their specific effects and optimal applications.
Upon analyzing the extracts, we found that the flower extract boasted a higher concentration of beneficial phenolic compounds compared to the berry extract. Importantly, when we tested how these extracts performed against cancerous cell lines, we noted variations in results. Both extracts reduced the formation of reactive oxygen species (ROS) in healthy cells under oxidative stress, with elderberry's effects being most pronounced in cancer cells.
The findings indicated a promising potential for these natural compounds, particularly elderberry, to be used in functional food formulations or as therapeutic agents against cancer. Thus, while the extracts generally showed a positive impact, further research is needed to fully understand their specific effects and optimal applications.
Read More
7
Elderflower extract shows anti-cancer promise
Chemical Characterization of L. Flowers Aqueous Extract and Its Biological Implications.
Directly addresses elderflower effects
We examined the effects of elderflower extracts on cancer, focusing on their chemical properties and potential health benefits. Using aqueous extractions at varying temperatures, we found that the extract heated to 90 °C had the highest levels of beneficial phenolic compounds and demonstrated notable antioxidant activity.
Analyzing this extract through advanced methods like GC-MS and HPLC-MS revealed 46 different compounds, primarily quercetin and chlorogenic acid derivatives, which made up a large percentage of the extract's phenolic content. We also identified naringenin as a significant component within the extract.
To assess its impact on cancer, we tested the elderflower extract on several colon cancer cell lines. The results indicated that the RKO cancer cells were particularly sensitive to the extract, with a significant inhibitory concentration observed. Additionally, the extract showed promise in combating certain Gram-positive bacteria.
These findings suggest that elderflower extracts could be valuable sources of bioactive compounds, potentially enhancing health and quality of life. This highlights their possibilities not only as foods but also in cosmetic and therapeutic applications.
Analyzing this extract through advanced methods like GC-MS and HPLC-MS revealed 46 different compounds, primarily quercetin and chlorogenic acid derivatives, which made up a large percentage of the extract's phenolic content. We also identified naringenin as a significant component within the extract.
To assess its impact on cancer, we tested the elderflower extract on several colon cancer cell lines. The results indicated that the RKO cancer cells were particularly sensitive to the extract, with a significant inhibitory concentration observed. Additionally, the extract showed promise in combating certain Gram-positive bacteria.
These findings suggest that elderflower extracts could be valuable sources of bioactive compounds, potentially enhancing health and quality of life. This highlights their possibilities not only as foods but also in cosmetic and therapeutic applications.
Read More
Most Useful Reviews
9.5
Cancer fighter
Very excellent; it is regarded as a cancer fighter and an antioxidant.
Read More
9.5
Cancer treatment aid
Black elderberry is effective against flu and colds and helps with cancer treatment. It helps remove toxins and has an immunomodulatory effect, aiding my health in dealing with cancer.
Read More
8.8
Cancer prevention
We always have it on hand! It has many polyphenols, preventing flu and stopping colds in their tracks. I drink it daily for its extraordinary anti-inflammatory and antioxidant benefits and to help prevent cancer.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 7 Researches
6.9
8
Elderberry's potential in cancer treatment
Transient receptor potential channel stimulation induced oxidative stress and apoptosis in the colon of mice with colitis-associated colon cancer: modulator role of Sambucus ebulus L.
Moderate relevance to cancer treatment
We explored the relationship between elderberry treatment and its effects on cancer, particularly in the context of colitis-associated colon cancer. In our study, 28 mice were divided into four groups, including those receiving elderberry and those with a cancer-inducing treatment known as AOM/DSS. This allowed us to compare the impact of elderberry on oxidative stress and apoptosis in the colon.
Our findings revealed that the activation of specific channels, TRPA1, TRPM2, and TRPV1, was associated with increased oxidative stress and cell death in cancerous cells. However, when the mice were treated with elderberry, these harmful effects seemed to diminish, suggesting elderberry might offer some protective benefits against cancer development in this model. While our results are encouraging, they highlight the potential of using elderberry as a complementary approach alongside other cancer treatments, rather than a standalone cure.
Ultimately, this research provides insights into how elderberry may influence cancer processes by modulating channel activity in the colon. The study’s results warrant further investigation, particularly in human contexts, to better understand elderberry's role in cancer prevention or treatment.
Our findings revealed that the activation of specific channels, TRPA1, TRPM2, and TRPV1, was associated with increased oxidative stress and cell death in cancerous cells. However, when the mice were treated with elderberry, these harmful effects seemed to diminish, suggesting elderberry might offer some protective benefits against cancer development in this model. While our results are encouraging, they highlight the potential of using elderberry as a complementary approach alongside other cancer treatments, rather than a standalone cure.
Ultimately, this research provides insights into how elderberry may influence cancer processes by modulating channel activity in the colon. The study’s results warrant further investigation, particularly in human contexts, to better understand elderberry's role in cancer prevention or treatment.
Read More
8
Elderberry protein's anticancer potential
Recombinant pebulin protein, a type 2 ribosome-inactivating protein isolated from dwarf elder (Sambucus ebulus L.) shows anticancer and antifungal activities in vitro.
Strong focus on cancer effects
We focused on a newly identified protein called pebulin, derived from dwarf elder, and examined its potential anticancer effects. The protein was successfully produced in E. coli and purified for further testing.
Our tests revealed that pebulin is not only capable of agglutinating red blood cells from all human blood types but also has significant inhibitory effects on cancer cell lines like MCF-7 and HT-29. This means that pebulin could slow down the growth of these cancer cells, a promising outcome we found particularly exciting.
Additionally, we noted that pebulin demonstrated effectiveness against certain plant fungi, showcasing its versatile bioactivity. The study suggests that pebulin may offer a new avenue for cancer treatment, particularly considering its impact on both cancer cells and fungi.
Our tests revealed that pebulin is not only capable of agglutinating red blood cells from all human blood types but also has significant inhibitory effects on cancer cell lines like MCF-7 and HT-29. This means that pebulin could slow down the growth of these cancer cells, a promising outcome we found particularly exciting.
Additionally, we noted that pebulin demonstrated effectiveness against certain plant fungi, showcasing its versatile bioactivity. The study suggests that pebulin may offer a new avenue for cancer treatment, particularly considering its impact on both cancer cells and fungi.
Read More
7
Elderberry extracts show cancer potential
flower and berry extracts for food and therapeutic applications: effect of gastrointestinal digestion on and bioactivity and toxicity.
Berry extracts effectiveness noted
We delved into how flower and berry extracts, with a focus on elderberry, affect cancer cells and assess their potential benefits in nutrition and therapy. The study investigated the behavior of these extracts before and after digestion to understand their bioavailability and effects on toxicity.
Upon analyzing the extracts, we found that the flower extract boasted a higher concentration of beneficial phenolic compounds compared to the berry extract. Importantly, when we tested how these extracts performed against cancerous cell lines, we noted variations in results. Both extracts reduced the formation of reactive oxygen species (ROS) in healthy cells under oxidative stress, with elderberry's effects being most pronounced in cancer cells.
The findings indicated a promising potential for these natural compounds, particularly elderberry, to be used in functional food formulations or as therapeutic agents against cancer. Thus, while the extracts generally showed a positive impact, further research is needed to fully understand their specific effects and optimal applications.
Upon analyzing the extracts, we found that the flower extract boasted a higher concentration of beneficial phenolic compounds compared to the berry extract. Importantly, when we tested how these extracts performed against cancerous cell lines, we noted variations in results. Both extracts reduced the formation of reactive oxygen species (ROS) in healthy cells under oxidative stress, with elderberry's effects being most pronounced in cancer cells.
The findings indicated a promising potential for these natural compounds, particularly elderberry, to be used in functional food formulations or as therapeutic agents against cancer. Thus, while the extracts generally showed a positive impact, further research is needed to fully understand their specific effects and optimal applications.
Read More
7
Elderberry's potential in cancer treatment
Black Elder and Its Constituents: Molecular Mechanisms of Action Associated with Female Reproduction.
Indicates positive cancer treatment effects
We examined the potential effects of elderberry, particularly its bioactive compounds, on cancer, focusing on ovarian cells. Our review highlighted how extracts from black elder berry can stimulate the viability and hormone production in healthy ovarian cells. This is promising, as it suggests the extract may have beneficial roles in boosting reproductive health.
Importantly, we also noted that elderberry constituents like rutin, anthocyanins, and agglutinins show the ability to reduce the proliferation of ovarian cancer cells. These compounds seem to promote apoptosis, or programmed cell death, which is a crucial process in eliminating unhealthy cells.
While the studies conducted so far have limitations, the initial findings indicate that elderberry could be useful in both preventing and treating reproductive disorders in veterinary and human medicine. There's still much to discover, but the path forward appears promising for those looking into cancer treatments and reproductive health improvement through natural means.
Importantly, we also noted that elderberry constituents like rutin, anthocyanins, and agglutinins show the ability to reduce the proliferation of ovarian cancer cells. These compounds seem to promote apoptosis, or programmed cell death, which is a crucial process in eliminating unhealthy cells.
While the studies conducted so far have limitations, the initial findings indicate that elderberry could be useful in both preventing and treating reproductive disorders in veterinary and human medicine. There's still much to discover, but the path forward appears promising for those looking into cancer treatments and reproductive health improvement through natural means.
Read More
7
Elderflower extract shows anti-cancer promise
Chemical Characterization of L. Flowers Aqueous Extract and Its Biological Implications.
Directly addresses elderflower effects
We examined the effects of elderflower extracts on cancer, focusing on their chemical properties and potential health benefits. Using aqueous extractions at varying temperatures, we found that the extract heated to 90 °C had the highest levels of beneficial phenolic compounds and demonstrated notable antioxidant activity.
Analyzing this extract through advanced methods like GC-MS and HPLC-MS revealed 46 different compounds, primarily quercetin and chlorogenic acid derivatives, which made up a large percentage of the extract's phenolic content. We also identified naringenin as a significant component within the extract.
To assess its impact on cancer, we tested the elderflower extract on several colon cancer cell lines. The results indicated that the RKO cancer cells were particularly sensitive to the extract, with a significant inhibitory concentration observed. Additionally, the extract showed promise in combating certain Gram-positive bacteria.
These findings suggest that elderflower extracts could be valuable sources of bioactive compounds, potentially enhancing health and quality of life. This highlights their possibilities not only as foods but also in cosmetic and therapeutic applications.
Analyzing this extract through advanced methods like GC-MS and HPLC-MS revealed 46 different compounds, primarily quercetin and chlorogenic acid derivatives, which made up a large percentage of the extract's phenolic content. We also identified naringenin as a significant component within the extract.
To assess its impact on cancer, we tested the elderflower extract on several colon cancer cell lines. The results indicated that the RKO cancer cells were particularly sensitive to the extract, with a significant inhibitory concentration observed. Additionally, the extract showed promise in combating certain Gram-positive bacteria.
These findings suggest that elderflower extracts could be valuable sources of bioactive compounds, potentially enhancing health and quality of life. This highlights their possibilities not only as foods but also in cosmetic and therapeutic applications.
Read More
User Reviews
USERS' SCORE
Good
Based on 5 Reviews
8.6
9.5
Cancer fighter
Very excellent; it is regarded as a cancer fighter and an antioxidant.
9.5
Cancer treatment aid
Black elderberry is effective against flu and colds and helps with cancer treatment. It helps remove toxins and has an immunomodulatory effect, aiding my health in dealing with cancer.
8.8
Cancer prevention
We always have it on hand! It has many polyphenols, preventing flu and stopping colds in their tracks. I drink it daily for its extraordinary anti-inflammatory and antioxidant benefits and to help prevent cancer.
8.8
Cancer support
It works wonderfully. I take it mainly for prevention and also gave it to my father-in-law during his battle with cancer, supporting his health for over a year.
8
Cancer cell prevention
Elderberry has diuretic, anti-inflammatory, and antioxidant effects, beneficial for colds, respiratory diseases, and even cancer. Dried elderberries may aid those suffering from malaria or stomach cancer, while the fibre content helps remove cholesterol from the body, reducing cardiovascular disease risks.
Read More
