Last update
5/25/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7
USERS' SCORE
Good
Based on 18 Reviews
8.4
Supplement Facts
Serving Size: 2 tablets
Amount Per Serving
%DV
Pancreatic EnzymesUsp Units Of Activity:Amylase 81,250 UspProtease 81,250 UspLipase 6,500 Usp
361 mg
**
Trypsin
75 mg
**
Papain
50 mg
**
Bromelain
16 mg
**
Amylase
10 mg
**
Lipase
10 mg
**
Chymotrypsin
2 mg
**
Top Medical Research Studies
7
Spasmocanulase aids IBS symptom relief
We investigated how spasmocanulase could help those struggling with irritable bowel syndrome (IBS), particularly focusing on symptoms like bloating. In a clinic in Riyadh, 21 patients who had not found relief with other medications were given spasmocanulase three times a day for six months.
The results showed over half of the participants experienced improvements in bloating and abdominal pain. In fact, symptom relief was noted in 43-75% of patients, marking a significant change from their prior treatments.
While the sample size was small, this suggests spasmocanulase may offer real benefits for IBS symptoms.
The results showed over half of the participants experienced improvements in bloating and abdominal pain. In fact, symptom relief was noted in 43-75% of patients, marking a significant change from their prior treatments.
While the sample size was small, this suggests spasmocanulase may offer real benefits for IBS symptoms.
Read More
7
We investigated whether probiotics or digestive enzymes could alleviate gastrointestinal symptoms following gastric bypass surgery. In this double-blind trial, 60 patients were assigned to receive either probiotics or digestive enzymes, including pancreatin, for two weeks.
After the intervention, we noticed a significant improvement in various symptoms like bloating and gas among all groups. This indicates that both types of treatment could enhance quality of life for patients grappling with post-surgery GI issues.
After the intervention, we noticed a significant improvement in various symptoms like bloating and gas among all groups. This indicates that both types of treatment could enhance quality of life for patients grappling with post-surgery GI issues.
Read More
Most Useful Reviews
10
Relief achieved
8 people found this helpful
Real relief. Finally, I can eat any meal, and as long as I take two tabs right before or with my meal, the dreadful bloating, pain, and gas have become a thing of the past. I will be ordering it again and want to thank you for having it available!
Read More
9
No bloating
4 people found this helpful
My mum is thrilled with these enzymes. She feels fantastic, free from bloating. Her bowel movements have normalised. We’ll have her health tested to confirm these benefits. Please click YES!
Read More
7.5
Bloating disappears
3 people found this helpful
I have IBS, which causes digestive issues. A colleague suggested Mega-Zyme, and it complements my usual medications well. Even if taken post-meal, the bloated feeling vanishes almost immediately. When I forget them, I notice the difference and regret it. These pills are now a part of my daily routine!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7
- All Researches
7
We investigated whether probiotics or digestive enzymes could alleviate gastrointestinal symptoms following gastric bypass surgery. In this double-blind trial, 60 patients were assigned to receive either probiotics or digestive enzymes, including pancreatin, for two weeks.
After the intervention, we noticed a significant improvement in various symptoms like bloating and gas among all groups. This indicates that both types of treatment could enhance quality of life for patients grappling with post-surgery GI issues.
After the intervention, we noticed a significant improvement in various symptoms like bloating and gas among all groups. This indicates that both types of treatment could enhance quality of life for patients grappling with post-surgery GI issues.
Read More
7
Spasmocanulase aids IBS symptom relief
We investigated how spasmocanulase could help those struggling with irritable bowel syndrome (IBS), particularly focusing on symptoms like bloating. In a clinic in Riyadh, 21 patients who had not found relief with other medications were given spasmocanulase three times a day for six months.
The results showed over half of the participants experienced improvements in bloating and abdominal pain. In fact, symptom relief was noted in 43-75% of patients, marking a significant change from their prior treatments.
While the sample size was small, this suggests spasmocanulase may offer real benefits for IBS symptoms.
The results showed over half of the participants experienced improvements in bloating and abdominal pain. In fact, symptom relief was noted in 43-75% of patients, marking a significant change from their prior treatments.
While the sample size was small, this suggests spasmocanulase may offer real benefits for IBS symptoms.
Read More
User Reviews
USERS' SCORE
Good
Based on 18 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
10
Relief achieved
8 people found this helpful
Real relief. Finally, I can eat any meal, and as long as I take two tabs right before or with my meal, the dreadful bloating, pain, and gas have become a thing of the past. I will be ordering it again and want to thank you for having it available!
Read More
9
No bloating
4 people found this helpful
My mum is thrilled with these enzymes. She feels fantastic, free from bloating. Her bowel movements have normalised. We’ll have her health tested to confirm these benefits. Please click YES!
Read More
7.5
Bloating disappears
3 people found this helpful
I have IBS, which causes digestive issues. A colleague suggested Mega-Zyme, and it complements my usual medications well. Even if taken post-meal, the bloated feeling vanishes almost immediately. When I forget them, I notice the difference and regret it. These pills are now a part of my daily routine!
Read More
9
Improved digestion
2 people found this helpful
My pancreas is weak, and these enzymes help significantly. My digestive system operates much better now, with no bloating or discomfort!
Read More
9
Effective enzymes
1 people found this helpful
These are the best enzymes I've tried for digestion and bloating. I take one pill before meals, and it works wonders, alleviating my bloating issues. The small size makes them easy to swallow, and I highly recommend them.
Read More
Frequently Asked Questions
7.5
Bloating disappears
3 people found this helpful
I have IBS, which causes digestive issues. A colleague suggested Mega-Zyme, and it complements my usual medications well. Even if taken post-meal, the bloated feeling vanishes almost immediately. When I forget them, I notice the difference and regret it. These pills are now a part of my daily routine!
9
Light stomach
This is an excellent product. I used to suffer from bloating and gas after meals, but since I started taking these enzymes, I feel a sense of lightness in my stomach and intestines.
7
We investigated whether probiotics or digestive enzymes could alleviate gastrointestinal symptoms following gastric bypass surgery. In this double-blind trial, 60 patients were assigned to receive either probiotics or digestive enzymes, including pancreatin, for two weeks.
After the intervention, we noticed a significant improvement in various symptoms like bloating and gas among all groups. This indicates that both types of treatment could enhance quality of life for patients grappling with post-surgery GI issues.
After the intervention, we noticed a significant improvement in various symptoms like bloating and gas among all groups. This indicates that both types of treatment could enhance quality of life for patients grappling with post-surgery GI issues.
7
Spasmocanulase aids IBS symptom relief
We investigated how spasmocanulase could help those struggling with irritable bowel syndrome (IBS), particularly focusing on symptoms like bloating. In a clinic in Riyadh, 21 patients who had not found relief with other medications were given spasmocanulase three times a day for six months.
The results showed over half of the participants experienced improvements in bloating and abdominal pain. In fact, symptom relief was noted in 43-75% of patients, marking a significant change from their prior treatments.
While the sample size was small, this suggests spasmocanulase may offer real benefits for IBS symptoms.
The results showed over half of the participants experienced improvements in bloating and abdominal pain. In fact, symptom relief was noted in 43-75% of patients, marking a significant change from their prior treatments.
While the sample size was small, this suggests spasmocanulase may offer real benefits for IBS symptoms.
References
- Chen JC, Lee WJ, Tsou JJ, Liu TP, Tsai PL. Effect of probiotics on postoperative quality of gastric bypass surgeries: a prospective randomized trial. Surg Obes Relat Dis. 2016;12:57. 10.1016/j.soard.2015.07.010
- Mohamed AE, Ghandour ZM, Al-Karawi MA. Spasmocanulase in irritable bowel syndrome. Saudi Med J. 2002;23:1074. PubMed
