5/5/2025
Last update
5/5/2025
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
USERS' SCORE
Good
Based on 44 Reviews
8.7
Supplement Facts
Serving Size: 2 Capsules
Amount Per Serving
%DV
Total Carbohydrate
<1 g
<1%†
Calcium (from calcium magnesium phytate)
131 mg
10%
Phosphorus (from calcium magnesium phytate)
192 mg
15%
Magnesium (from calcium magnesium phytate)
40 mg
10%
IP-6 (inositol hexaphosphate) (from calcium magnesium phytate)
800 mg
**
Inositol
220 mg
**
Top Medical Research Studies
9
We investigated the potential benefits of Myo-inositol, a naturally occurring sugar alcohol, on DU-145 prostate cancer cells. By treating these cancer cells with various doses of Myo-inositol, we determined its half-maximal inhibitory concentration (IC50) using a simple method that measures cell viability.
Our findings revealed that Myo-inositol significantly decreased the viability of DU-145 cells, showing an IC50 of 0.06 mg/ml. This suggests that Myo-inositol may effectively inhibit cancer cell growth.
Furthermore, we performed a detailed proteomic analysis using advanced techniques to explore how Myo-inositol changes protein expression. We found notable differences in protein levels between treated and untreated cells, particularly in areas linked to key cellular functions like cytoskeletal regulation, apoptosis (cell death), and stress responses. For instance, certain proteins tied to tumor suppression were upregulated in response to Myo-inositol treatment.
Overall, these observations highlight Myo-inositol's potential as a therapeutic option. However, further studies are necessary to unravel the underlying mechanisms and assess its effectiveness in combination with other treatments for managing prostate cancer, especially castration-resistant prostate cancer (CRPC).
Our findings revealed that Myo-inositol significantly decreased the viability of DU-145 cells, showing an IC50 of 0.06 mg/ml. This suggests that Myo-inositol may effectively inhibit cancer cell growth.
Furthermore, we performed a detailed proteomic analysis using advanced techniques to explore how Myo-inositol changes protein expression. We found notable differences in protein levels between treated and untreated cells, particularly in areas linked to key cellular functions like cytoskeletal regulation, apoptosis (cell death), and stress responses. For instance, certain proteins tied to tumor suppression were upregulated in response to Myo-inositol treatment.
Overall, these observations highlight Myo-inositol's potential as a therapeutic option. However, further studies are necessary to unravel the underlying mechanisms and assess its effectiveness in combination with other treatments for managing prostate cancer, especially castration-resistant prostate cancer (CRPC).
Read More
9
We investigated how isogarcinol (ISO) influences breast cancer cells and what mechanisms are at play. Through lab tests, we found that ISO at 13 μM effectively lowered cell growth and movement. In living subjects, doses of 5 to 15 mg/kg showed a significant reduction in tumor activity.
We observed that ISO achieves its tumor-suppressing effects by lowering the levels of a protein called methionyl-tRNA synthetase (MARS) and deactivating key pathways involved in cancer progression. These findings suggest ISO could be a valuable addition to breast cancer treatment strategies.
We observed that ISO achieves its tumor-suppressing effects by lowering the levels of a protein called methionyl-tRNA synthetase (MARS) and deactivating key pathways involved in cancer progression. These findings suggest ISO could be a valuable addition to breast cancer treatment strategies.
Read More
7
Vitamin E Succinate enhances autophagy
We examined how vitamin E succinate (VES) affects autophagy in human gastric cancer cells by activating a calcium signaling pathway. Our study involved cultured gastric cancer cell lines treated with various doses of VES. We noted that VES significantly reduced cell proliferation and enhanced the formation of autophagosomes, indicating increased autophagy.
However, when we inhibited the calcium channel involved, the positive effects of VES diminished, suggesting the importance of this pathway in its action. Overall, while VES shows promise in promoting autophagy, further research is needed to understand its full potential in cancer treatment.
However, when we inhibited the calcium channel involved, the positive effects of VES diminished, suggesting the importance of this pathway in its action. Overall, while VES shows promise in promoting autophagy, further research is needed to understand its full potential in cancer treatment.
Read More
Most Useful Reviews
10
Active cancer treatment
319 people found this helpful
This is the best I-P6 product available. It works wonders to shrink tumours. I have effectively halted my cancer twice using this product – two pills in the morning and two at night for maintenance. Studies indicate it begins working at doses of 8 mg. It also benefits immune health and is suitable for the entire family; I highly recommend it.
Read More
9
Long-term survivor
319 people found this helpful
I've experienced incredible results with IP6. My mother-in-law first introduced it during my father-in-law's fight against Stage IV colon cancer, where he refused chemo. He changed his diet and took just one pill of IP6 daily. Twenty years later, he never had a recurrence of cancer! Although he eventually passed away from renal failure at age 92, this changed my perspective entirely. It sounds unbelievable, but I assure you it’s true.
Read More
9
Extra time with husband
289 people found this helpful
Eighteen years ago, my husband was diagnosed with terminal liver cancer and given little time to live. IP-6 significantly improved his immune system and extended his life by three years beyond expectations. Since then, I have introduced many friends to this extraordinary product, which has helped each of them. I now use IP-6 due to my own health issues and support my friend undergoing chemotherapy with it.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
- All Researches
9
We investigated the potential benefits of Myo-inositol, a naturally occurring sugar alcohol, on DU-145 prostate cancer cells. By treating these cancer cells with various doses of Myo-inositol, we determined its half-maximal inhibitory concentration (IC50) using a simple method that measures cell viability.
Our findings revealed that Myo-inositol significantly decreased the viability of DU-145 cells, showing an IC50 of 0.06 mg/ml. This suggests that Myo-inositol may effectively inhibit cancer cell growth.
Furthermore, we performed a detailed proteomic analysis using advanced techniques to explore how Myo-inositol changes protein expression. We found notable differences in protein levels between treated and untreated cells, particularly in areas linked to key cellular functions like cytoskeletal regulation, apoptosis (cell death), and stress responses. For instance, certain proteins tied to tumor suppression were upregulated in response to Myo-inositol treatment.
Overall, these observations highlight Myo-inositol's potential as a therapeutic option. However, further studies are necessary to unravel the underlying mechanisms and assess its effectiveness in combination with other treatments for managing prostate cancer, especially castration-resistant prostate cancer (CRPC).
Our findings revealed that Myo-inositol significantly decreased the viability of DU-145 cells, showing an IC50 of 0.06 mg/ml. This suggests that Myo-inositol may effectively inhibit cancer cell growth.
Furthermore, we performed a detailed proteomic analysis using advanced techniques to explore how Myo-inositol changes protein expression. We found notable differences in protein levels between treated and untreated cells, particularly in areas linked to key cellular functions like cytoskeletal regulation, apoptosis (cell death), and stress responses. For instance, certain proteins tied to tumor suppression were upregulated in response to Myo-inositol treatment.
Overall, these observations highlight Myo-inositol's potential as a therapeutic option. However, further studies are necessary to unravel the underlying mechanisms and assess its effectiveness in combination with other treatments for managing prostate cancer, especially castration-resistant prostate cancer (CRPC).
Read More
9
We investigated how isogarcinol (ISO) influences breast cancer cells and what mechanisms are at play. Through lab tests, we found that ISO at 13 μM effectively lowered cell growth and movement. In living subjects, doses of 5 to 15 mg/kg showed a significant reduction in tumor activity.
We observed that ISO achieves its tumor-suppressing effects by lowering the levels of a protein called methionyl-tRNA synthetase (MARS) and deactivating key pathways involved in cancer progression. These findings suggest ISO could be a valuable addition to breast cancer treatment strategies.
We observed that ISO achieves its tumor-suppressing effects by lowering the levels of a protein called methionyl-tRNA synthetase (MARS) and deactivating key pathways involved in cancer progression. These findings suggest ISO could be a valuable addition to breast cancer treatment strategies.
Read More
7
Vitamin E Succinate enhances autophagy
We examined how vitamin E succinate (VES) affects autophagy in human gastric cancer cells by activating a calcium signaling pathway. Our study involved cultured gastric cancer cell lines treated with various doses of VES. We noted that VES significantly reduced cell proliferation and enhanced the formation of autophagosomes, indicating increased autophagy.
However, when we inhibited the calcium channel involved, the positive effects of VES diminished, suggesting the importance of this pathway in its action. Overall, while VES shows promise in promoting autophagy, further research is needed to understand its full potential in cancer treatment.
However, when we inhibited the calcium channel involved, the positive effects of VES diminished, suggesting the importance of this pathway in its action. Overall, while VES shows promise in promoting autophagy, further research is needed to understand its full potential in cancer treatment.
Read More
User Reviews
USERS' SCORE
Good
Based on 44 Reviews
8.7
- All Reviews
- Positive Reviews
- Negative Reviews
10
Active cancer treatment
319 people found this helpful
This is the best I-P6 product available. It works wonders to shrink tumours. I have effectively halted my cancer twice using this product – two pills in the morning and two at night for maintenance. Studies indicate it begins working at doses of 8 mg. It also benefits immune health and is suitable for the entire family; I highly recommend it.
Read More
9
Long-term survivor
319 people found this helpful
I've experienced incredible results with IP6. My mother-in-law first introduced it during my father-in-law's fight against Stage IV colon cancer, where he refused chemo. He changed his diet and took just one pill of IP6 daily. Twenty years later, he never had a recurrence of cancer! Although he eventually passed away from renal failure at age 92, this changed my perspective entirely. It sounds unbelievable, but I assure you it’s true.
Read More
9
Extra time with husband
289 people found this helpful
Eighteen years ago, my husband was diagnosed with terminal liver cancer and given little time to live. IP-6 significantly improved his immune system and extended his life by three years beyond expectations. Since then, I have introduced many friends to this extraordinary product, which has helped each of them. I now use IP-6 due to my own health issues and support my friend undergoing chemotherapy with it.
Read More
10
Saved lives
144 people found this helpful
KILLS CANCER! I know six people who have taken this, and it impressively combats cancer. My mother’s life was saved from pancreatic cancer, and everyone I know who used this has seen their cancer disappear.
Read More
9
Cured skin cancer
130 people found this helpful
I've been using this for nearly a decade and love it! Although they advise against such claims, I cured my own skin cancer with high doses of this product. Additionally, it enhances my skin's appearance and helps me maintain a youthful look. I can't recommend it highly enough.
Read More
Frequently Asked Questions
9
Vital for health
Great Must have for immunity and cancer survivors. I am taking more than the suggested amount.
9
We investigated the potential benefits of Myo-inositol, a naturally occurring sugar alcohol, on DU-145 prostate cancer cells. By treating these cancer cells with various doses of Myo-inositol, we determined its half-maximal inhibitory concentration (IC50) using a simple method that measures cell viability.
Our findings revealed that Myo-inositol significantly decreased the viability of DU-145 cells, showing an IC50 of 0.06 mg/ml. This suggests that Myo-inositol may effectively inhibit cancer cell growth.
Furthermore, we performed a detailed proteomic analysis using advanced techniques to explore how Myo-inositol changes protein expression. We found notable differences in protein levels between treated and untreated cells, particularly in areas linked to key cellular functions like cytoskeletal regulation, apoptosis (cell death), and stress responses. For instance, certain proteins tied to tumor suppression were upregulated in response to Myo-inositol treatment.
Overall, these observations highlight Myo-inositol's potential as a therapeutic option. However, further studies are necessary to unravel the underlying mechanisms and assess its effectiveness in combination with other treatments for managing prostate cancer, especially castration-resistant prostate cancer (CRPC).
Our findings revealed that Myo-inositol significantly decreased the viability of DU-145 cells, showing an IC50 of 0.06 mg/ml. This suggests that Myo-inositol may effectively inhibit cancer cell growth.
Furthermore, we performed a detailed proteomic analysis using advanced techniques to explore how Myo-inositol changes protein expression. We found notable differences in protein levels between treated and untreated cells, particularly in areas linked to key cellular functions like cytoskeletal regulation, apoptosis (cell death), and stress responses. For instance, certain proteins tied to tumor suppression were upregulated in response to Myo-inositol treatment.
Overall, these observations highlight Myo-inositol's potential as a therapeutic option. However, further studies are necessary to unravel the underlying mechanisms and assess its effectiveness in combination with other treatments for managing prostate cancer, especially castration-resistant prostate cancer (CRPC).
7
Vitamin E Succinate enhances autophagy
We examined how vitamin E succinate (VES) affects autophagy in human gastric cancer cells by activating a calcium signaling pathway. Our study involved cultured gastric cancer cell lines treated with various doses of VES. We noted that VES significantly reduced cell proliferation and enhanced the formation of autophagosomes, indicating increased autophagy.
However, when we inhibited the calcium channel involved, the positive effects of VES diminished, suggesting the importance of this pathway in its action. Overall, while VES shows promise in promoting autophagy, further research is needed to understand its full potential in cancer treatment.
However, when we inhibited the calcium channel involved, the positive effects of VES diminished, suggesting the importance of this pathway in its action. Overall, while VES shows promise in promoting autophagy, further research is needed to understand its full potential in cancer treatment.
9
We investigated how isogarcinol (ISO) influences breast cancer cells and what mechanisms are at play. Through lab tests, we found that ISO at 13 μM effectively lowered cell growth and movement. In living subjects, doses of 5 to 15 mg/kg showed a significant reduction in tumor activity.
We observed that ISO achieves its tumor-suppressing effects by lowering the levels of a protein called methionyl-tRNA synthetase (MARS) and deactivating key pathways involved in cancer progression. These findings suggest ISO could be a valuable addition to breast cancer treatment strategies.
We observed that ISO achieves its tumor-suppressing effects by lowering the levels of a protein called methionyl-tRNA synthetase (MARS) and deactivating key pathways involved in cancer progression. These findings suggest ISO could be a valuable addition to breast cancer treatment strategies.
References
- Islam MJ, Muntaha S, Masum MM, Nowshin S, Salam S, et al. Proteomic Analysis of Anticancer Effect of Myo-inositol in Human Prostate Cancer (DU-145) Cell Line. Asian Pac J Cancer Prev. 2024;25:4447. 10.31557/APJCP.2024.25.12.4447
- Wen XY, Cao MM, Zhang ZY, Xie N, Wei ZY, et al. [The role of endoplasmic reticulum IP(3)R calcium channel in vitamin E succinate induced autophagy of human gastric cancer cell]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2025;43:180. 10.3760/cma.j.cn121094-20240125-00037
- Zhang D, Chu Y, Li M, Du L. Isogarcinol Reduces MARS Levels and Deactivates the PI3K/AKT Pathway to Suppress the Malignant Properties of Breast Cancer Cells. Cell Biochem Biophys. 2025. 10.1007/s12013-025-01727-0
