Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 23 Researches
7.5
USERS' SCORE
Moderately Good
Based on 45 Reviews
7.8
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Lactobacillus acidophilus (La-14)
2 Billion CFU
*
Top Medical Research Studies
9
Probiotics improve constipation symptoms
We conducted a randomized, placebo-controlled trial involving 92 children aged 4 to 12 with functional constipation. Over four weeks, we provided one group with a probiotic chewable tablet containing specific strains and compared their experiences to a placebo group.
The findings were promising; the probiotic group reported a significant improvement in stool frequency and a decrease in hard defecation. Specifically, hard stools decreased from 43% to 14%, while normal defecation increased from 56% to 80%. This study highlights the potential of probiotics as a valuable option for managing constipation in children.
The findings were promising; the probiotic group reported a significant improvement in stool frequency and a decrease in hard defecation. Specifically, hard stools decreased from 43% to 14%, while normal defecation increased from 56% to 80%. This study highlights the potential of probiotics as a valuable option for managing constipation in children.
Read More
7
We aimed to understand if lactic acid bacteria (LAB) could help nursing home residents with chronic constipation. In a study with 19 residents, we administered LAB twice daily for two weeks and tracked their bowel habits through questionnaires and fecal samples.
The results showed that LAB supplementation improved defecation frequency and stool quality. This suggests that incorporating LAB into regular treatment may be a useful strategy for enhancing digestive health in the elderly.
The results showed that LAB supplementation improved defecation frequency and stool quality. This suggests that incorporating LAB into regular treatment may be a useful strategy for enhancing digestive health in the elderly.
Read More
8
Synbiotics beneficial for constipation relief
This randomized controlled trial explored how synbiotics affect constipation and quality of life in chronic hemodialysis patients. Despite not reducing indoxyl sulphate toxin levels after two months, we found that the use of Lactobacillus acidophilus and Bifidobacterium longum significantly improved constipation symptoms and overall quality of life.
The study involved a double-blinded setup to ensure fairness, with participants divided into synbiotics and placebo groups. Caregivers and outcome assessors were also blinded, ensuring objective results. Thus, while toxin levels remained unchanged, the benefits for constipation were clear.
The study involved a double-blinded setup to ensure fairness, with participants divided into synbiotics and placebo groups. Caregivers and outcome assessors were also blinded, ensuring objective results. Thus, while toxin levels remained unchanged, the benefits for constipation were clear.
Read More
Most Useful Reviews
10
Daily bowel movement
8 people found this helpful
The effect is remarkable. I have tried numerous lactic acid bacteria and probiotics, yet nothing matches this product. Initially, I experienced constipation, but since using it, I now go daily. It's been a game-changer for my bowel health and will also assist those seeking to lose weight.
Read More
9
Improved digestion
5 people found this helpful
I began using this product for better intestinal health, as I believe all diseases stem from gut issues. Since then, my digestion has improved, and my wife no longer suffers from colic. I highly recommend this for anyone struggling with constipation or poor digestion.
Read More
9
Avoid constipation
3 people found this helpful
After my haemorrhoid surgery, avoiding constipation was crucial. I tried several supplements, but this dietary supplement worked wonders. I highly recommend it for its effectiveness.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 23 Researches
7.5
- All Researches
9.5
Cultured milk drink relieves constipation
We explored the impact of a cultured milk drink containing Lactobacillus acidophilus on constipation symptoms in adults with constipation-predominant irritable bowel syndrome (IBS-C). Over 30 days, 77 participants drank this yogurt-like beverage daily.
Post-treatment, a staggering 97.4% of participants reported improvement in their symptoms, including decreased intestinal transit time and lower fecal pH. Notably, the levels of inflammatory cytokines also dropped significantly, suggesting potential benefits of this treatment for IBS-C patients.
Post-treatment, a staggering 97.4% of participants reported improvement in their symptoms, including decreased intestinal transit time and lower fecal pH. Notably, the levels of inflammatory cytokines also dropped significantly, suggesting potential benefits of this treatment for IBS-C patients.
Read More
9
Probiotics improve constipation symptoms
We conducted a randomized, placebo-controlled trial involving 92 children aged 4 to 12 with functional constipation. Over four weeks, we provided one group with a probiotic chewable tablet containing specific strains and compared their experiences to a placebo group.
The findings were promising; the probiotic group reported a significant improvement in stool frequency and a decrease in hard defecation. Specifically, hard stools decreased from 43% to 14%, while normal defecation increased from 56% to 80%. This study highlights the potential of probiotics as a valuable option for managing constipation in children.
The findings were promising; the probiotic group reported a significant improvement in stool frequency and a decrease in hard defecation. Specifically, hard stools decreased from 43% to 14%, while normal defecation increased from 56% to 80%. This study highlights the potential of probiotics as a valuable option for managing constipation in children.
Read More
9
We evaluated how lactobacillus acidophilus, both alone and in a mix with other bacteria, might relieve constipation caused by loperamide in rats. Over 14 days, we noticed that the groups receiving probiotics had significantly heavier and wetter stools compared to control animals.
Notably, the CKDBP group, a blend of multiple bacteria, showed the greatest improvement in intestinal transit. Measures like mucosal length and mucus secretion were also significantly enhanced in all probiotic-treated groups, highlighting their potential to alleviate constipation symptoms effectively.
Notably, the CKDBP group, a blend of multiple bacteria, showed the greatest improvement in intestinal transit. Measures like mucosal length and mucus secretion were also significantly enhanced in all probiotic-treated groups, highlighting their potential to alleviate constipation symptoms effectively.
Read More
8
Synbiotics beneficial for constipation relief
This randomized controlled trial explored how synbiotics affect constipation and quality of life in chronic hemodialysis patients. Despite not reducing indoxyl sulphate toxin levels after two months, we found that the use of Lactobacillus acidophilus and Bifidobacterium longum significantly improved constipation symptoms and overall quality of life.
The study involved a double-blinded setup to ensure fairness, with participants divided into synbiotics and placebo groups. Caregivers and outcome assessors were also blinded, ensuring objective results. Thus, while toxin levels remained unchanged, the benefits for constipation were clear.
The study involved a double-blinded setup to ensure fairness, with participants divided into synbiotics and placebo groups. Caregivers and outcome assessors were also blinded, ensuring objective results. Thus, while toxin levels remained unchanged, the benefits for constipation were clear.
Read More
8
Yogurt may aid constipation relief
We explored the impact of daily yogurt consumption containing polydextrose and probiotic strains L. acidophilus NCFM and B. lactis HN019 on chronic constipation. Patients were divided into two groups, with one group receiving the active yogurt and the other only plain yogurt for 14 days.
At the end of the study, those in the yogurt treatment group experienced a significant decrease in colonic transit time compared to the control group. This suggests that such a yogurt product may be a beneficial option for those struggling with constipation.
At the end of the study, those in the yogurt treatment group experienced a significant decrease in colonic transit time compared to the control group. This suggests that such a yogurt product may be a beneficial option for those struggling with constipation.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 45 Reviews
7.8
- All Reviews
- Positive Reviews
- Negative Reviews
10
Daily bowel movement
8 people found this helpful
The effect is remarkable. I have tried numerous lactic acid bacteria and probiotics, yet nothing matches this product. Initially, I experienced constipation, but since using it, I now go daily. It's been a game-changer for my bowel health and will also assist those seeking to lose weight.
Read More
9
Improved digestion
5 people found this helpful
I began using this product for better intestinal health, as I believe all diseases stem from gut issues. Since then, my digestion has improved, and my wife no longer suffers from colic. I highly recommend this for anyone struggling with constipation or poor digestion.
Read More
9
Avoid constipation
3 people found this helpful
After my haemorrhoid surgery, avoiding constipation was crucial. I tried several supplements, but this dietary supplement worked wonders. I highly recommend it for its effectiveness.
Read More
7.5
Constipation daily
3 people found this helpful
My constipation has significantly improved; it was once every 2-3 days, but now it's daily. However, if I skip taking it, the issue returns. I'm considering switching to a product with more bacteria if this one doesn’t continue to work.
Read More
9
Immediate effect
2 people found this helpful
I often face constipation issues and, after reading positive reviews, I decided to try this product. Taking one tablet on an empty stomach in the morning stimulates a strong urge to visit the toilet after breakfast. I will continue using it!
Read More
Frequently Asked Questions
7.5
Consistent results
1 people found this helpful
It takes a few days to see results, but this supplement effectively treats constipation. It's easier and more economical than eating yogurt daily, so I've opted for a larger bottle.
9
Effective for bowel movements
After finishing one bottle, I found it very effective. I took one on a day I was constipated, and my bowel movements were normal by the next day.
7.5
Constipation daily
3 people found this helpful
My constipation has significantly improved; it was once every 2-3 days, but now it's daily. However, if I skip taking it, the issue returns. I'm considering switching to a product with more bacteria if this one doesn’t continue to work.
10
Daily bowel movement
8 people found this helpful
The effect is remarkable. I have tried numerous lactic acid bacteria and probiotics, yet nothing matches this product. Initially, I experienced constipation, but since using it, I now go daily. It's been a game-changer for my bowel health and will also assist those seeking to lose weight.
9
Effective remedy
1 people found this helpful
This product significantly improved my digestion; my constipation has resolved and my stool has normalised. I definitely find this supplement effective and would recommend it to others.
8
Comfortable digestion
2 people found this helpful
Mixing this with a 3 billion probiotics supplement has improved my intestinal environment. I now experience daily comfort regarding constipation and will continue with this product.
7
We explored the effects of two different probiotic formulations designed to tackle functional constipation in adults. Participants took an oral sachet daily for 30 days in a randomized, double-blind trial.
Both probiotic mixes improved constipation symptoms by increasing the frequency of bowel movements and enhancing stool quality. However, no significant differences were found among the treatment groups. Overall, the probiotics were safe, with only one report of abdominal pain in a participant.
Both probiotic mixes improved constipation symptoms by increasing the frequency of bowel movements and enhancing stool quality. However, no significant differences were found among the treatment groups. Overall, the probiotics were safe, with only one report of abdominal pain in a participant.
7
We studied the effects of multistrain probiotics on constipation in elderly nursing home residents. Sixty participants took either a specific probiotic mixture or a placebo over 12 weeks in a double-blind setup.
While there was a slight but not statistically significant increase in stool frequency overall, those receiving probiotics showed a notable increase in stool frequency post-day 71 when laxative use was considered.
Overall, the probiotics were well tolerated and deemed safe for treating functional constipation in this population.
While there was a slight but not statistically significant increase in stool frequency overall, those receiving probiotics showed a notable increase in stool frequency post-day 71 when laxative use was considered.
Overall, the probiotics were well tolerated and deemed safe for treating functional constipation in this population.
9.5
Cultured milk drink relieves constipation
We explored the impact of a cultured milk drink containing Lactobacillus acidophilus on constipation symptoms in adults with constipation-predominant irritable bowel syndrome (IBS-C). Over 30 days, 77 participants drank this yogurt-like beverage daily.
Post-treatment, a staggering 97.4% of participants reported improvement in their symptoms, including decreased intestinal transit time and lower fecal pH. Notably, the levels of inflammatory cytokines also dropped significantly, suggesting potential benefits of this treatment for IBS-C patients.
Post-treatment, a staggering 97.4% of participants reported improvement in their symptoms, including decreased intestinal transit time and lower fecal pH. Notably, the levels of inflammatory cytokines also dropped significantly, suggesting potential benefits of this treatment for IBS-C patients.
9
Probiotics improve constipation symptoms
We conducted a randomized, placebo-controlled trial involving 92 children aged 4 to 12 with functional constipation. Over four weeks, we provided one group with a probiotic chewable tablet containing specific strains and compared their experiences to a placebo group.
The findings were promising; the probiotic group reported a significant improvement in stool frequency and a decrease in hard defecation. Specifically, hard stools decreased from 43% to 14%, while normal defecation increased from 56% to 80%. This study highlights the potential of probiotics as a valuable option for managing constipation in children.
The findings were promising; the probiotic group reported a significant improvement in stool frequency and a decrease in hard defecation. Specifically, hard stools decreased from 43% to 14%, while normal defecation increased from 56% to 80%. This study highlights the potential of probiotics as a valuable option for managing constipation in children.
8
We looked into how probiotics, specifically those containing Lactobacillus acidophilus, can help patients recover after colorectal cancer surgery.
Patients completed questionnaires on bowel function and quality of life before and after taking probiotics for three months.
The results showed improvements in defecation frequency and overall quality of life across multiple surgery types.
This indicates that probiotics may indeed play a beneficial role in recovery from colorectal surgery.
Patients completed questionnaires on bowel function and quality of life before and after taking probiotics for three months.
The results showed improvements in defecation frequency and overall quality of life across multiple surgery types.
This indicates that probiotics may indeed play a beneficial role in recovery from colorectal surgery.
4
We aimed to explore how a multi-strain probiotic product might help improve bowel habits in adults with functional constipation. In our randomized, double-blind study with 94 participants, we found that both those taking probiotics and those on placebo experienced over 20% improvement in symptoms.
Notably, the probiotic group showed benefits earlier, with a faster return to normal stool frequency and consistency. While there were no significant differences in overall symptom scores, we did observe positive changes in gut microbiota among probiotic users.
Notably, the probiotic group showed benefits earlier, with a faster return to normal stool frequency and consistency. While there were no significant differences in overall symptom scores, we did observe positive changes in gut microbiota among probiotic users.
References
- Mitelmão FCR, Häckel K, Bergamaschi CC, Gerenutti M, Silva MT, et al. The effect of probiotics on functional constipation in adults: A randomized, double-blind controlled trial. Medicine (Baltimore). 2022;101:e31185. 10.1097/MD.0000000000031185
- Šola KF, Vladimir-Knežević S, Hrabač P, Mucalo I, Saso L, et al. The effect of multistrain probiotics on functional constipation in the elderly: a randomized controlled trial. Eur J Clin Nutr. 2022;76:1675. 10.1038/s41430-022-01189-0
- Lydia A, Indra TA, Rizka A, Abdullah M. The effects of synbiotics on indoxyl sulphate level, constipation, and quality of life associated with constipation in chronic haemodialysis patients: a randomized controlled trial. BMC Nephrol. 2022;23:259. 10.1186/s12882-022-02890-9
- Mokhtar NM, Jaafar NM, Alfian E, Mohd Rathi ND, Abdul Rani R, et al. Clinical assessment and cytokines level in constipation-predominant irritable bowel syndrome participants treated with Lactobacillus-containing cultured milk drink. Acta Gastroenterol Belg. 2021;84:585. 10.51821/84.4.009
- Martoni CJ, Evans M, Chow CT, Chan LS, Leyer G. Impact of a probiotic product on bowel habits and microbial profile in participants with functional constipation: A randomized controlled trial. J Dig Dis. 2019;20:435. 10.1111/1751-2980.12797
- Airaksinen K, Yeung N, Lyra A, Lahtinen SJ, Huttunen T, et al. The effect of a probiotic blend on gastrointestinal symptoms in constipated patients: a double blind, randomised, placebo controlled 2-week trial. Benef Microbes. 2019;10:617. 10.3920/BM2018.0163
- Magro DO, de Oliveira LM, Bernasconi I, Ruela Mde S, Credidio L, et al. Effect of yogurt containing polydextrose, Lactobacillus acidophilus NCFM and Bifidobacterium lactis HN019: a randomized, double-blind, controlled study in chronic constipation. Nutr J. 2014;13:75. 10.1186/1475-2891-13-75
- Ohigashi S, Hoshino Y, Ohde S, Onodera H. Functional outcome, quality of life, and efficacy of probiotics in postoperative patients with colorectal cancer. Surg Today. 2011;41:1200. 10.1007/s00595-010-4450-6
- Tabbers MM, de Milliano I, Roseboom MG, Benninga MA. Is Bifidobacterium breve effective in the treatment of childhood constipation? Results from a pilot study. Nutr J. 2011;10:19. 10.1186/1475-2891-10-19
- Jeon JR, Choi JH. Lactic acid fermentation of germinated barley fiber and proliferative function of colonic epithelial cells in loperamide-induced rats. J Med Food. 2010;13:950. 10.1089/jmf.2009.1307
- Lamiki P, Tsuchiya J, Pathak S, Okura R, Solimene U, et al. Probiotics in diverticular disease of the colon: an open label study. J Gastrointestin Liver Dis. 2010;19:31.
- An HM, Baek EH, Jang S, Lee DK, Kim MJ, et al. Efficacy of Lactic Acid Bacteria (LAB) supplement in management of constipation among nursing home residents. Nutr J. 2010;9:5. 10.1186/1475-2891-9-5
- Drouault-Holowacz S, Bieuvelet S, Burckel A, Cazaubiel M, Dray X, et al. A double blind randomized controlled trial of a probiotic combination in 100 patients with irritable bowel syndrome. Gastroenterol Clin Biol. 2008;32:147. 10.1016/j.gcb.2007.06.001
- Astegiano M, Pellicano R, Terzi E, Simondi D, Rizzetto M. Treatment of irritable bowel syndrome. A case control experience. Minerva Gastroenterol Dietol. 2006;52:359.
- Tsuchiya J, Barreto R, Okura R, Kawakita S, Fesce E, et al. Single-blind follow-up study on the effectiveness of a symbiotic preparation in irritable bowel syndrome. Chin J Dig Dis. 2004;5:169.
- Alm L. [Acidophilus milk for therapy in gastrointestinal disorders]. Nahrung. 1984;28:683.
- Liao Y, Wang Y, Huang W, Wang J, Guo M, et al. L. acidophilus/L. johnsonii ratio affects slow transit constipation in rats. Sci Rep. 2024;14:21088. 10.1038/s41598-024-71945-8
- Gan D, Chen J, Tang X, Xiao L, Martoni CJ, et al. Impact of a probiotic chewable tablet on stool habits and microbial profile in children with functional constipation: A randomized controlled clinical trial. Front Microbiol. 2022;13:985308. 10.3389/fmicb.2022.985308
- Lin B, Zhao F, Liu Y, Wu X, Feng J, et al. Randomized Clinical Trial: Probiotics Alleviated Oral-Gut Microbiota Dysbiosis and Thyroid Hormone Withdrawal-Related Complications in Thyroid Cancer Patients Before Radioiodine Therapy Following Thyroidectomy. Front Endocrinol (Lausanne). 2022;13:834674. 10.3389/fendo.2022.834674
- Leventogiannis K, Gkolfakis P, Spithakis G, Tsatali A, Pistiki A, et al. Effect of a Preparation of Four Probiotics on Symptoms of Patients with Irritable Bowel Syndrome: Association with Intestinal Bacterial Overgrowth. Probiotics Antimicrob Proteins. 2019;11:627. 10.1007/s12602-018-9401-3
- Kim BK, Choi IS, Kim J, Han SH, Suh HJ, et al. Effects of Fermented Milk with Mixed Strains as a Probiotic on the Inhibition of Loperamide-Induced Constipation. Korean J Food Sci Anim Resour. 2017;37:906. 10.5851/kosfa.2017.37.6.906
- Choi SC, Kim BJ, Rhee PL, Chang DK, Son HJ, et al. Probiotic Fermented Milk Containing Dietary Fiber Has Additive Effects in IBS with Constipation Compared to Plain Probiotic Fermented Milk. Gut Liver. 2011;5:22. 10.5009/gnl.2011.5.1.22
- Nova E, Viadel B, Wärnberg J, Carreres JE, Marcos A. Beneficial effects of a synbiotic supplement on self-perceived gastrointestinal well-being and immunoinflammatory status of healthy adults. J Med Food. 2011;14:79. 10.1089/jmf.2008.0328
