Can NOW Supplements Coral Calcium Help with Cancer?

SCIENTIFIC SCORE

Questionable

Based on 3 Researches

6.3

USERS' SCORE

Good

Based on 1 Review

8.5

Supplement Facts

Serving Size: 1 Veg Capsule

Amount Per Serving

%DV

Calcium (from Fossilized Coral Calcium)

350 mg

27%

Fossilized Coral Calcium

1 g (1,000 mg)

†

Top Medical Research Studies

Calcium treatment impacts cancer viability

Investigation of the Bystander Effect on Cell Viability After Application of Combined Electroporation-Based Methods.

Calcium relevance in cancer treatment

We investigated how calcium treatment, in conjunction with various electroporation methods, affects cancer cell viability. In our study, we used 4T1 breast cancer cells and applied different forms of electroporation, such as reversible and irreversible treatments along with calcium electroporation. We were particularly interested in the bystander effect, where treated cells might affect untreated nearby cells.

By transferring conditioned media from the treated to untreated cells, we observed significant impacts on cell viability. The results showed that after applying calcium electroporation and bleomycin treatments, colony formation plummeted to nearly zero, and metabolic activity dipped as low as 11.62%. Additionally, other assessments, including flow cytometry, confirmed a drastic decrease in cell viability in the presence of calcium therapy.

While the study highlighted calcium’s role in enhancing the effects of electroporation, the combined treatments reduced the overall viability of surrounding cells markedly. We also noticed a delay in wound healing with conditioned media, indicating that calcium treatment could significantly impact not just treated but also neighboring cancer cells. Overall, calcium's combined effects were powerful, emphasizing its utility in cancer treatment strategies.

Calcium's role in cancer dynamics

Calcium levels modulate platelet function, platelet-cancer cell interaction, and cancer cell invasion.

Moderate relevance to cancer research

We examined how calcium levels impact the interactions between platelets and cancer cells, as these interactions are crucial for cancer metastasis. Our focus was on specific platelet receptors called integrins, which play vital roles in these interactions.

Throughout our study, we discovered that calcium significantly affects the functionality of these integrins and the overall behavior of platelets. When we reduced calcium levels, we noticed a change in how platelets interacted with breast cancer cells (specifically MDA-MB-231). On the contrary, environments with high calcium levels did not seem to affect these interactions as significantly.

Interestingly, we observed that hypercalcemia, or elevated calcium levels, appeared to enhance cancer cell invasion in the presence of platelets for both breast and lung cancer cells (MDA-MB-231 and A549, respectively). This suggests that rather than obstructing metastatic processes, high calcium may facilitate cancer spread, offering a new perspective on calcium's role in cancer dynamics.

Overall, this study sheds light on how calcium adjustments could be viewed not only as a potential therapeutic strategy but also as a factor impacting cancer progression, especially through platelet interactions.

Calcium-Vitamin D benefits post-surgery

Effects of vitamin D and calcium supplementation on bone of young adults after thyroidectomy of differentiated thyroid carcinoma.

Moderate relevance to calcium effects

We explored the impact of calcium and vitamin D supplementation on bone health in young adults after surgery for differentiated thyroid carcinoma (DTC). This study focused on patients under 50 years who had thyroidectomy and were experiencing vitamin D deficiency or insufficiency.

Over the course of one year, we provided patients with daily calcium and vitamin D supplements, monitoring their bone metabolism along the way. After analyzing results from 458 patients, we found that those receiving the supplements had lower levels of parathyroid hormone (PTH) and a notable increase in bone mineral density (BMD) at both the lumbar spine and hip compared to those who did not receive any supplements.

Our findings suggest that calcium, combined with vitamin D, can play a beneficial role in reducing bone loss in young DTC patients suffering from vitamin D malnutrition after thyroid surgery. This could mean improved bone health and a reduced risk of osteoporosis for these patients in the future.