Overview
SCIENTIFIC SCORE
Questionable
Based on 7 Researches
6.6
USERS' SCORE
Good
Based on 163 Reviews
8.4
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Inositol
500 mg
**
Top Medical Research Studies
8
We conducted a study to understand how inositol, a naturally occurring sugar alcohol, influences anxiety levels in laying hens. Our focus was on the behavior of Lohmann LSL lite hens, which were fed two different diets—one rich and one deficient in protein—while receiving either pure inositol or high levels of phytase.
Throughout the experimental period from 19 to 59 weeks of age, we gathered data through multiple behavior assessments, which included observing their reactions to new objects and monitoring their overall health indicators like feather condition and mortality rates.
Interestingly, inositol appeared to help reduce fearfulness in these hens, which we observed through a decrease in the time it took for them to approach and peck at new objects. However, it's worth noting that while inositol also led to a drop in vent feather cover and was associated with a slight increase in mortality, its primary benefit was tied to its ability to lessen anxiety.
Phytase, on the other hand, did not yield similar effects on behavior or health. These findings point towards the potential of inositol as a useful dietary addition for improving the well-being of laying hens by reducing anxiety levels.
Throughout the experimental period from 19 to 59 weeks of age, we gathered data through multiple behavior assessments, which included observing their reactions to new objects and monitoring their overall health indicators like feather condition and mortality rates.
Interestingly, inositol appeared to help reduce fearfulness in these hens, which we observed through a decrease in the time it took for them to approach and peck at new objects. However, it's worth noting that while inositol also led to a drop in vent feather cover and was associated with a slight increase in mortality, its primary benefit was tied to its ability to lessen anxiety.
Phytase, on the other hand, did not yield similar effects on behavior or health. These findings point towards the potential of inositol as a useful dietary addition for improving the well-being of laying hens by reducing anxiety levels.
Read More
8
We examined user sentiments surrounding treatments for Polycystic Ovary Syndrome (PCOS) through data collected from an extensive subreddit.
Our analysis revealed that lifestyle changes and supplements were viewed positively, while contraceptives often received negative feedback. Notably, inositol was associated with significant improvements in mental health, including reductions in anxiety.
This study highlights the potential of machine learning to analyze patient experiences, offering valuable insights that might complement traditional clinical research.
Our analysis revealed that lifestyle changes and supplements were viewed positively, while contraceptives often received negative feedback. Notably, inositol was associated with significant improvements in mental health, including reductions in anxiety.
This study highlights the potential of machine learning to analyze patient experiences, offering valuable insights that might complement traditional clinical research.
Read More
8
We explored how d-pinitol, a natural compound found in various fruits and legumes, could impact anxiety and related conditions. In our evaluation, we focused on its effects on mice to understand its potential as an anxiolytic agent.
During our study, we observed that when mice were given d-pinitol at doses ranging from 1 to 100 mg/kg, there was notable evidence of anxiolytic-like actions. In particular, at a dose of 70 mg/kg, d-pinitol showed significant effectiveness in reducing anxiety as assessed in specific behavioral tests.
We also investigated the possible mechanisms behind these effects. Our findings suggest that the GABAergic system may play a key role in mediating the anxiolytic benefits of d-pinitol, which indicates a promising direction for further research. It’s important to remember that while our results are encouraging, d-pinitol did not exhibit diuretic effects, which was a secondary focus of the study.
All in all, our study positions d-pinitol as a compelling candidate for alleviating anxiety, with mechanisms worth exploring further for therapeutic applications.
During our study, we observed that when mice were given d-pinitol at doses ranging from 1 to 100 mg/kg, there was notable evidence of anxiolytic-like actions. In particular, at a dose of 70 mg/kg, d-pinitol showed significant effectiveness in reducing anxiety as assessed in specific behavioral tests.
We also investigated the possible mechanisms behind these effects. Our findings suggest that the GABAergic system may play a key role in mediating the anxiolytic benefits of d-pinitol, which indicates a promising direction for further research. It’s important to remember that while our results are encouraging, d-pinitol did not exhibit diuretic effects, which was a secondary focus of the study.
All in all, our study positions d-pinitol as a compelling candidate for alleviating anxiety, with mechanisms worth exploring further for therapeutic applications.
Read More
Most Useful Reviews
9
Effective alternative treatment
574 people found this helpful
Proven effective for OCD and anxiety! I was initially sceptical about inositol but saw significant improvement in my son's severe OCD and my own anxiety after following a prescribed dosage. Despite being used to medications with severe side effects, inositol has shown promising results. It seems it requires a high dose for mental health conditions, but side effects are mild. I highly recommend it as a viable option.
Read More
9
Life-changing effects
513 people found this helpful
This stuff is a lifesaver! I was struggling with severe OCD, anxiety, panic attacks, and depression for months. I felt like I was in a hell of violent intrusive thoughts and massive anxiety. After trying various medications with no success, I turned to inositol. Although I didn’t notice its effects immediately, after 3-4 weeks, it transformed my life. I felt significantly better — about 60-70% improved, able to shop without fear of panic attacks and enjoy life again. Even my family dinners became manageable once more. Inositol has given me hope again, though I'm not yet completely cured.
Read More
6
Visible OCD improvement
78 people found this helpful
For those interested in Inositol for OCD. I’ve read studies showing high doses can significantly reduce OCD symptoms. I was sceptical at first but I've seen noticeable improvements in my anxiety and OCD, allowing for easier management of my symptoms. It feels as though inositol has helped to quieten my anxiety, making daily life more manageable.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 7 Researches
6.6
- All Researches
8
We conducted a study to understand how inositol, a naturally occurring sugar alcohol, influences anxiety levels in laying hens. Our focus was on the behavior of Lohmann LSL lite hens, which were fed two different diets—one rich and one deficient in protein—while receiving either pure inositol or high levels of phytase.
Throughout the experimental period from 19 to 59 weeks of age, we gathered data through multiple behavior assessments, which included observing their reactions to new objects and monitoring their overall health indicators like feather condition and mortality rates.
Interestingly, inositol appeared to help reduce fearfulness in these hens, which we observed through a decrease in the time it took for them to approach and peck at new objects. However, it's worth noting that while inositol also led to a drop in vent feather cover and was associated with a slight increase in mortality, its primary benefit was tied to its ability to lessen anxiety.
Phytase, on the other hand, did not yield similar effects on behavior or health. These findings point towards the potential of inositol as a useful dietary addition for improving the well-being of laying hens by reducing anxiety levels.
Throughout the experimental period from 19 to 59 weeks of age, we gathered data through multiple behavior assessments, which included observing their reactions to new objects and monitoring their overall health indicators like feather condition and mortality rates.
Interestingly, inositol appeared to help reduce fearfulness in these hens, which we observed through a decrease in the time it took for them to approach and peck at new objects. However, it's worth noting that while inositol also led to a drop in vent feather cover and was associated with a slight increase in mortality, its primary benefit was tied to its ability to lessen anxiety.
Phytase, on the other hand, did not yield similar effects on behavior or health. These findings point towards the potential of inositol as a useful dietary addition for improving the well-being of laying hens by reducing anxiety levels.
Read More
8
We explored how d-pinitol, a natural compound found in various fruits and legumes, could impact anxiety and related conditions. In our evaluation, we focused on its effects on mice to understand its potential as an anxiolytic agent.
During our study, we observed that when mice were given d-pinitol at doses ranging from 1 to 100 mg/kg, there was notable evidence of anxiolytic-like actions. In particular, at a dose of 70 mg/kg, d-pinitol showed significant effectiveness in reducing anxiety as assessed in specific behavioral tests.
We also investigated the possible mechanisms behind these effects. Our findings suggest that the GABAergic system may play a key role in mediating the anxiolytic benefits of d-pinitol, which indicates a promising direction for further research. It’s important to remember that while our results are encouraging, d-pinitol did not exhibit diuretic effects, which was a secondary focus of the study.
All in all, our study positions d-pinitol as a compelling candidate for alleviating anxiety, with mechanisms worth exploring further for therapeutic applications.
During our study, we observed that when mice were given d-pinitol at doses ranging from 1 to 100 mg/kg, there was notable evidence of anxiolytic-like actions. In particular, at a dose of 70 mg/kg, d-pinitol showed significant effectiveness in reducing anxiety as assessed in specific behavioral tests.
We also investigated the possible mechanisms behind these effects. Our findings suggest that the GABAergic system may play a key role in mediating the anxiolytic benefits of d-pinitol, which indicates a promising direction for further research. It’s important to remember that while our results are encouraging, d-pinitol did not exhibit diuretic effects, which was a secondary focus of the study.
All in all, our study positions d-pinitol as a compelling candidate for alleviating anxiety, with mechanisms worth exploring further for therapeutic applications.
Read More
8
We examined user sentiments surrounding treatments for Polycystic Ovary Syndrome (PCOS) through data collected from an extensive subreddit.
Our analysis revealed that lifestyle changes and supplements were viewed positively, while contraceptives often received negative feedback. Notably, inositol was associated with significant improvements in mental health, including reductions in anxiety.
This study highlights the potential of machine learning to analyze patient experiences, offering valuable insights that might complement traditional clinical research.
Our analysis revealed that lifestyle changes and supplements were viewed positively, while contraceptives often received negative feedback. Notably, inositol was associated with significant improvements in mental health, including reductions in anxiety.
This study highlights the potential of machine learning to analyze patient experiences, offering valuable insights that might complement traditional clinical research.
Read More
7
Myo-Inositol improves anxiety behavior
We aimed to explore the impact of myo-inositol (MI) on anxiety in a mouse model of classic galactosemia. Our research involved a combination of acute and chronic evaluations of MI, particularly looking at its effects over a long-term treatment period. We observed that lower doses of MI suggested notable improvements in motor deficits and anxiety-driven hyperactivity among the GalT-KO mice, which are affected by this condition.
While we conducted a thorough assessment of motor-related behaviors and anxiety levels, it appears that MI holds potential as an adjunct treatment option. These findings indicate that MI may benefit not only physical symptoms but also emotional well-being, particularly in reducing anxiety-related behaviors in this genetically modified model, which helps us understand its role more clearly. The results could point to new avenues for managing anxiety, especially in conditions like classic galactosemia where traditional treatment methods fall short.
While we conducted a thorough assessment of motor-related behaviors and anxiety levels, it appears that MI holds potential as an adjunct treatment option. These findings indicate that MI may benefit not only physical symptoms but also emotional well-being, particularly in reducing anxiety-related behaviors in this genetically modified model, which helps us understand its role more clearly. The results could point to new avenues for managing anxiety, especially in conditions like classic galactosemia where traditional treatment methods fall short.
Read More
7
Inositol as potential anxiety treatment
We examined the potential of inositol as a treatment for anxiety disorders. While several treatments are currently available, many patients still struggle with symptoms, leading us to seek out alternatives like inositol.
Our findings suggest that inositol may have anti-panic effects, indicating it is worth considering for those who haven’t found success with other medications. We noted that it was generally well tolerated, which is essential for anyone looking for anxiety relief without unpleasant side effects.
While inositol shows promise, further research is necessary to firmly establish its efficacy. In this case, it's important to keep expectations grounded and recognize that individual responses may vary.
Overall, inositol presents itself as a intriguing option, especially for patients facing treatment-resistant conditions, highlighting the ongoing need for fresh approaches to managing anxiety.
Our findings suggest that inositol may have anti-panic effects, indicating it is worth considering for those who haven’t found success with other medications. We noted that it was generally well tolerated, which is essential for anyone looking for anxiety relief without unpleasant side effects.
While inositol shows promise, further research is necessary to firmly establish its efficacy. In this case, it's important to keep expectations grounded and recognize that individual responses may vary.
Overall, inositol presents itself as a intriguing option, especially for patients facing treatment-resistant conditions, highlighting the ongoing need for fresh approaches to managing anxiety.
Read More
User Reviews
USERS' SCORE
Good
Based on 163 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Effective alternative treatment
574 people found this helpful
Proven effective for OCD and anxiety! I was initially sceptical about inositol but saw significant improvement in my son's severe OCD and my own anxiety after following a prescribed dosage. Despite being used to medications with severe side effects, inositol has shown promising results. It seems it requires a high dose for mental health conditions, but side effects are mild. I highly recommend it as a viable option.
Read More
9
Life-changing effects
513 people found this helpful
This stuff is a lifesaver! I was struggling with severe OCD, anxiety, panic attacks, and depression for months. I felt like I was in a hell of violent intrusive thoughts and massive anxiety. After trying various medications with no success, I turned to inositol. Although I didn’t notice its effects immediately, after 3-4 weeks, it transformed my life. I felt significantly better — about 60-70% improved, able to shop without fear of panic attacks and enjoy life again. Even my family dinners became manageable once more. Inositol has given me hope again, though I'm not yet completely cured.
Read More
6
Visible OCD improvement
78 people found this helpful
For those interested in Inositol for OCD. I’ve read studies showing high doses can significantly reduce OCD symptoms. I was sceptical at first but I've seen noticeable improvements in my anxiety and OCD, allowing for easier management of my symptoms. It feels as though inositol has helped to quieten my anxiety, making daily life more manageable.
Read More
10
Fast-acting relief
64 people found this helpful
So much suffering has vanished thanks to Inositol! I wish I had known about using this for anxiety and OCD earlier; it could have saved my loved one from a lot of pain. It worked incredibly quickly, producing a night-and-day difference, alleviating anxiety and obsessive thoughts. My loved one is taking 18 grams a day but approached it gradually to allow their system to adjust, increasing the dosage weekly.
Read More
7.5
Anxiety relief experienced
48 people found this helpful
Promising for anxiety and PCOS! I initially tried it for PCOS but saw dramatic improvements in my husband's anxiety. He feels relaxed and less stressed, while I have noticed myself being less easily agitated. This supplement has notably improved our motivation and overall wellbeing. I do wish it came in larger containers though, as the therapeutic dosage is significant.
Read More
Frequently Asked Questions
9
Eliminates anxiety
43 people found this helpful
This is my second time taking Inositol, and it effectively alleviates anxiety and nervousness within days. I find I can handle stressful situations more calmly without feeling drowsy or cloudy-headed. The supplement comes in easy-to-take capsules.
9
Enhanced mental health
6 people found this helpful
In my late 50s, I've struggled with sleep issues and anxiety. After just two weeks of taking inositol, I noticed improved sleep and a reduction in panic attacks. My anxiety levels have decreased significantly, making a positive difference in my mental health and overall outlook.
9
Alleviates OCD
10 people found this helpful
This inositol product has noticeably helped with my obsessive-compulsive disorder (OCD) and anxiety. I used to check tasks repeatedly. Now, instead of relying on prescription medication for anxiety before travelling, I simply take inositol an hour beforehand. It’s vegan and high-quality, with no adverse effects.
9
Anxiety relief
5 people found this helpful
I bought this supplement due to the reviews and noticed my anxiety vanished soon after I started taking it at night when I need to sleep well. I'll continue using it.
9
Stops panic attacks
26 people found this helpful
This product has been a revelation, completely eliminating my panic attacks and anxiety, allowing me to function normally again. It’s also reasonably priced, making it a great choice.
9
Life-changing effects
36 people found this helpful
Researching this product was worthwhile as it has transformed my life. I have hormonal imbalances and PCOS, and after using it, I've lost weight, gained energy, and no longer suffer from cravings or anxiety attacks. It has been a remarkable part of my wellness journey.
9
Stress reduction
11 people found this helpful
These capsules are a must-have for anyone with anxiety. I take three capsules three times a day, as per my doctor's advice, and have heard others with OCD and panic disorders taking even higher doses, often with great success.
8.5
Surprisingly effective
8 people found this helpful
My doctor recommended 3 grams of inositol daily for generalised anxiety. I was initially sceptical but have been pleasantly surprised by its effectiveness, requiring valium much less frequently. No side effects noted.
9
Anxiety relief
12 people found this helpful
This has significantly reduced my anxiety. I take a maximum of two pills daily, and the benefits have been enormous. I highly recommend it to anyone struggling with OCD, Bipolar disorder or depression.
9
Reduced panic attacks
7 people found this helpful
At 58, inositol has been my saviour for panic attacks. Initially hesitant about the dosage, I found that 6g daily works well for me. My panic attacks have lessened, and my anxiety is more manageable now. I appreciated Dr. Atkins' recommendations, which really helped guide my use of this supplement.
7
Myo-Inositol improves anxiety behavior
We aimed to explore the impact of myo-inositol (MI) on anxiety in a mouse model of classic galactosemia. Our research involved a combination of acute and chronic evaluations of MI, particularly looking at its effects over a long-term treatment period. We observed that lower doses of MI suggested notable improvements in motor deficits and anxiety-driven hyperactivity among the GalT-KO mice, which are affected by this condition.
While we conducted a thorough assessment of motor-related behaviors and anxiety levels, it appears that MI holds potential as an adjunct treatment option. These findings indicate that MI may benefit not only physical symptoms but also emotional well-being, particularly in reducing anxiety-related behaviors in this genetically modified model, which helps us understand its role more clearly. The results could point to new avenues for managing anxiety, especially in conditions like classic galactosemia where traditional treatment methods fall short.
While we conducted a thorough assessment of motor-related behaviors and anxiety levels, it appears that MI holds potential as an adjunct treatment option. These findings indicate that MI may benefit not only physical symptoms but also emotional well-being, particularly in reducing anxiety-related behaviors in this genetically modified model, which helps us understand its role more clearly. The results could point to new avenues for managing anxiety, especially in conditions like classic galactosemia where traditional treatment methods fall short.
4
We sought to understand the effects of inositol, a type of mitochondrial modulator, on anxiety as part of a broader examination of its role in treating obsessive-compulsive and related disorders. In this systematic review, we analyzed results from 17 double-blind, randomized, placebo-controlled trials involving 629 participants.
Our findings indicated that while inositol is included among several other treatments, its specific impact on anxiety-related scores did not surpass that of the placebo. Though overall symptoms improved with inositol and other mitochondrial modulators like N-acetylcysteine, the evidence for inositol alone does not demonstrate a significant advantage for anxiety relief.
Overall, while we enjoyed exploring the various treatments and their potential benefits, it is essential to note that inositol's effectiveness on its own concerning anxiety remains unproven when compared directly to placebo.
Our findings indicated that while inositol is included among several other treatments, its specific impact on anxiety-related scores did not surpass that of the placebo. Though overall symptoms improved with inositol and other mitochondrial modulators like N-acetylcysteine, the evidence for inositol alone does not demonstrate a significant advantage for anxiety relief.
Overall, while we enjoyed exploring the various treatments and their potential benefits, it is essential to note that inositol's effectiveness on its own concerning anxiety remains unproven when compared directly to placebo.
4
Myo-inositol shows no significant anxiety effects
Our study examined the effects of a combined supplement of myo-inositol, probiotics, and micronutrients on the mental wellbeing of women from preconception through pregnancy and into the post-delivery period. We designed a double-blind randomized trial to compare this specific supplement with a standard micronutrient supplement. Our goal was to see if the intervention could lead to reduced anxiety and improved mood in participants.
Throughout various stages of pregnancy and after delivery, we measured mood and anxiety levels using established scales. We found that while there were no significant differences between the supplement group and the control group in terms of anxiety and mood symptoms, there was a modest improvement in overall mental health functioning for those taking the combined supplement. Specifically, women in the intervention group experienced a slight uptick in their mental health scores by 1.21 points compared to the control group by six months post-delivery.
Ultimately, while our findings did not indicate a meaningful impact on anxiety levels, they do suggest that taking myo-inositol along with other nutrients could support overall mental health during the perinatal period, offering some benefits beyond mood and anxiety symptoms alone.
Throughout various stages of pregnancy and after delivery, we measured mood and anxiety levels using established scales. We found that while there were no significant differences between the supplement group and the control group in terms of anxiety and mood symptoms, there was a modest improvement in overall mental health functioning for those taking the combined supplement. Specifically, women in the intervention group experienced a slight uptick in their mental health scores by 1.21 points compared to the control group by six months post-delivery.
Ultimately, while our findings did not indicate a meaningful impact on anxiety levels, they do suggest that taking myo-inositol along with other nutrients could support overall mental health during the perinatal period, offering some benefits beyond mood and anxiety symptoms alone.
8
We explored how d-pinitol, a natural compound found in various fruits and legumes, could impact anxiety and related conditions. In our evaluation, we focused on its effects on mice to understand its potential as an anxiolytic agent.
During our study, we observed that when mice were given d-pinitol at doses ranging from 1 to 100 mg/kg, there was notable evidence of anxiolytic-like actions. In particular, at a dose of 70 mg/kg, d-pinitol showed significant effectiveness in reducing anxiety as assessed in specific behavioral tests.
We also investigated the possible mechanisms behind these effects. Our findings suggest that the GABAergic system may play a key role in mediating the anxiolytic benefits of d-pinitol, which indicates a promising direction for further research. It’s important to remember that while our results are encouraging, d-pinitol did not exhibit diuretic effects, which was a secondary focus of the study.
All in all, our study positions d-pinitol as a compelling candidate for alleviating anxiety, with mechanisms worth exploring further for therapeutic applications.
During our study, we observed that when mice were given d-pinitol at doses ranging from 1 to 100 mg/kg, there was notable evidence of anxiolytic-like actions. In particular, at a dose of 70 mg/kg, d-pinitol showed significant effectiveness in reducing anxiety as assessed in specific behavioral tests.
We also investigated the possible mechanisms behind these effects. Our findings suggest that the GABAergic system may play a key role in mediating the anxiolytic benefits of d-pinitol, which indicates a promising direction for further research. It’s important to remember that while our results are encouraging, d-pinitol did not exhibit diuretic effects, which was a secondary focus of the study.
All in all, our study positions d-pinitol as a compelling candidate for alleviating anxiety, with mechanisms worth exploring further for therapeutic applications.
References
- Bellagamba O, Guo AJ, Senthilkumar S, Lillevik SH, De Biase D, et al. Assessment of Long-Term Safety and Efficacy of Purple Sweet Potato Color (PSPC) and Myo-Inositol (MI) Treatment for Motor Related and Behavioral Phenotypes in a Mouse Model of Classic Galactosemia. J Inherit Metab Dis. 2025;48:e70002. doi:10.1002/jimd.70002
- El-Heis S, Barton SJ, Chang HF, Nield H, Cox V, et al. Maternal mood, anxiety and mental health functioning after combined myo-inositol, probiotics, micronutrient supplementation from preconception: Findings from the NiPPeR RCT. Psychiatry Res. 2024;334:115813. doi:10.1016/j.psychres.2024.115813
- Kishi T, Sakuma K, Iwata N. Mitochondrial modulators for obsessive-compulsive and related disorders: a systematic review and meta-analysis. Transl Psychiatry. 2022;12:263. doi:10.1038/s41398-022-02026-5
- Herwig E, Classen HL, Walk CL, Bedford M, Schwean-Lardner K. Dietary Inositol Reduces Fearfulness and Avoidance in Laying Hens. Animals (Basel). 2019;9. doi:10.3390/ani9110938
- Alonso-Castro AJ, Alba-Betancourt C, Rocha-González E, Ruiz-Arredondo A, Zapata-Morales JR, et al. Neuropharmacological effects of d-pinitol and its possible mechanisms of action. J Food Biochem. 2019;43:e13070. doi:10.1111/jfbc.13070
- Zulfarina MS, Syarifah-Noratiqah SB, Nazrun SA, Sharif R, Naina-Mohamed I. Pharmacological Therapy in Panic Disorder: Current Guidelines and Novel Drugs Discovery for Treatment-resistant Patient. Clin Psychopharmacol Neurosci. 2019;17:145. doi:10.9758/cpn.2019.17.2.145
- Emanuel RHK, Docherty PD, Lunt H, Campbell RE. What do users in a polycystic ovary syndrome (PCOS) forum think about the treatments they tried: Analysing treatment sentiment using machine learning. Phys Eng Sci Med. 2025. doi:10.1007/s13246-025-01539-9
