Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
USERS' SCORE
Good
Based on 7 Reviews
8.3
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Inositol
500 mg
**
Top Medical Research Studies
9
We investigated the potential benefits of Myo-inositol, a naturally occurring sugar alcohol, on DU-145 prostate cancer cells. By treating these cancer cells with various doses of Myo-inositol, we determined its half-maximal inhibitory concentration (IC50) using a simple method that measures cell viability.
Our findings revealed that Myo-inositol significantly decreased the viability of DU-145 cells, showing an IC50 of 0.06 mg/ml. This suggests that Myo-inositol may effectively inhibit cancer cell growth.
Furthermore, we performed a detailed proteomic analysis using advanced techniques to explore how Myo-inositol changes protein expression. We found notable differences in protein levels between treated and untreated cells, particularly in areas linked to key cellular functions like cytoskeletal regulation, apoptosis (cell death), and stress responses. For instance, certain proteins tied to tumor suppression were upregulated in response to Myo-inositol treatment.
Overall, these observations highlight Myo-inositol's potential as a therapeutic option. However, further studies are necessary to unravel the underlying mechanisms and assess its effectiveness in combination with other treatments for managing prostate cancer, especially castration-resistant prostate cancer (CRPC).
Our findings revealed that Myo-inositol significantly decreased the viability of DU-145 cells, showing an IC50 of 0.06 mg/ml. This suggests that Myo-inositol may effectively inhibit cancer cell growth.
Furthermore, we performed a detailed proteomic analysis using advanced techniques to explore how Myo-inositol changes protein expression. We found notable differences in protein levels between treated and untreated cells, particularly in areas linked to key cellular functions like cytoskeletal regulation, apoptosis (cell death), and stress responses. For instance, certain proteins tied to tumor suppression were upregulated in response to Myo-inositol treatment.
Overall, these observations highlight Myo-inositol's potential as a therapeutic option. However, further studies are necessary to unravel the underlying mechanisms and assess its effectiveness in combination with other treatments for managing prostate cancer, especially castration-resistant prostate cancer (CRPC).
Read More
9
We investigated how isogarcinol (ISO) influences breast cancer cells and what mechanisms are at play. Through lab tests, we found that ISO at 13 μM effectively lowered cell growth and movement. In living subjects, doses of 5 to 15 mg/kg showed a significant reduction in tumor activity.
We observed that ISO achieves its tumor-suppressing effects by lowering the levels of a protein called methionyl-tRNA synthetase (MARS) and deactivating key pathways involved in cancer progression. These findings suggest ISO could be a valuable addition to breast cancer treatment strategies.
We observed that ISO achieves its tumor-suppressing effects by lowering the levels of a protein called methionyl-tRNA synthetase (MARS) and deactivating key pathways involved in cancer progression. These findings suggest ISO could be a valuable addition to breast cancer treatment strategies.
Read More
7
Vitamin E Succinate enhances autophagy
We examined how vitamin E succinate (VES) affects autophagy in human gastric cancer cells by activating a calcium signaling pathway. Our study involved cultured gastric cancer cell lines treated with various doses of VES. We noted that VES significantly reduced cell proliferation and enhanced the formation of autophagosomes, indicating increased autophagy.
However, when we inhibited the calcium channel involved, the positive effects of VES diminished, suggesting the importance of this pathway in its action. Overall, while VES shows promise in promoting autophagy, further research is needed to understand its full potential in cancer treatment.
However, when we inhibited the calcium channel involved, the positive effects of VES diminished, suggesting the importance of this pathway in its action. Overall, while VES shows promise in promoting autophagy, further research is needed to understand its full potential in cancer treatment.
Read More
Most Useful Reviews
9
Post-surgery support
7 people found this helpful
So far so fantastic! I cannot afford similar products elsewhere, and this has helped me immensely, especially after my hysterectomy and during early menopause due to having cancer. I will continue purchasing, and now my friends are doing the same.
Read More
9
Menstrual cycle restoration
Unbelievably, inositol has been instrumental in treating polycystic ovaries, aiding hormonal balance, stabilising the cardiovascular system, and prompting ovulation. It helps to lower triglycerides and reduces the risk of cancer.
Read More
7.5
Cancer risk reduction
Inositol, the most bioavailable form of vitamin B8, offers numerous benefits, such as reducing cancer risk. It helps normalise metabolism, improve lipid profiles, and lowers blood glucose without harmful side effects.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
- All Researches
9
We investigated the potential benefits of Myo-inositol, a naturally occurring sugar alcohol, on DU-145 prostate cancer cells. By treating these cancer cells with various doses of Myo-inositol, we determined its half-maximal inhibitory concentration (IC50) using a simple method that measures cell viability.
Our findings revealed that Myo-inositol significantly decreased the viability of DU-145 cells, showing an IC50 of 0.06 mg/ml. This suggests that Myo-inositol may effectively inhibit cancer cell growth.
Furthermore, we performed a detailed proteomic analysis using advanced techniques to explore how Myo-inositol changes protein expression. We found notable differences in protein levels between treated and untreated cells, particularly in areas linked to key cellular functions like cytoskeletal regulation, apoptosis (cell death), and stress responses. For instance, certain proteins tied to tumor suppression were upregulated in response to Myo-inositol treatment.
Overall, these observations highlight Myo-inositol's potential as a therapeutic option. However, further studies are necessary to unravel the underlying mechanisms and assess its effectiveness in combination with other treatments for managing prostate cancer, especially castration-resistant prostate cancer (CRPC).
Our findings revealed that Myo-inositol significantly decreased the viability of DU-145 cells, showing an IC50 of 0.06 mg/ml. This suggests that Myo-inositol may effectively inhibit cancer cell growth.
Furthermore, we performed a detailed proteomic analysis using advanced techniques to explore how Myo-inositol changes protein expression. We found notable differences in protein levels between treated and untreated cells, particularly in areas linked to key cellular functions like cytoskeletal regulation, apoptosis (cell death), and stress responses. For instance, certain proteins tied to tumor suppression were upregulated in response to Myo-inositol treatment.
Overall, these observations highlight Myo-inositol's potential as a therapeutic option. However, further studies are necessary to unravel the underlying mechanisms and assess its effectiveness in combination with other treatments for managing prostate cancer, especially castration-resistant prostate cancer (CRPC).
Read More
9
We investigated how isogarcinol (ISO) influences breast cancer cells and what mechanisms are at play. Through lab tests, we found that ISO at 13 μM effectively lowered cell growth and movement. In living subjects, doses of 5 to 15 mg/kg showed a significant reduction in tumor activity.
We observed that ISO achieves its tumor-suppressing effects by lowering the levels of a protein called methionyl-tRNA synthetase (MARS) and deactivating key pathways involved in cancer progression. These findings suggest ISO could be a valuable addition to breast cancer treatment strategies.
We observed that ISO achieves its tumor-suppressing effects by lowering the levels of a protein called methionyl-tRNA synthetase (MARS) and deactivating key pathways involved in cancer progression. These findings suggest ISO could be a valuable addition to breast cancer treatment strategies.
Read More
7
Vitamin E Succinate enhances autophagy
We examined how vitamin E succinate (VES) affects autophagy in human gastric cancer cells by activating a calcium signaling pathway. Our study involved cultured gastric cancer cell lines treated with various doses of VES. We noted that VES significantly reduced cell proliferation and enhanced the formation of autophagosomes, indicating increased autophagy.
However, when we inhibited the calcium channel involved, the positive effects of VES diminished, suggesting the importance of this pathway in its action. Overall, while VES shows promise in promoting autophagy, further research is needed to understand its full potential in cancer treatment.
However, when we inhibited the calcium channel involved, the positive effects of VES diminished, suggesting the importance of this pathway in its action. Overall, while VES shows promise in promoting autophagy, further research is needed to understand its full potential in cancer treatment.
Read More
User Reviews
USERS' SCORE
Good
Based on 7 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
Post-surgery support
7 people found this helpful
So far so fantastic! I cannot afford similar products elsewhere, and this has helped me immensely, especially after my hysterectomy and during early menopause due to having cancer. I will continue purchasing, and now my friends are doing the same.
Read More
9
Menstrual cycle restoration
Unbelievably, inositol has been instrumental in treating polycystic ovaries, aiding hormonal balance, stabilising the cardiovascular system, and prompting ovulation. It helps to lower triglycerides and reduces the risk of cancer.
Read More
7.5
Cancer risk reduction
Inositol, the most bioavailable form of vitamin B8, offers numerous benefits, such as reducing cancer risk. It helps normalise metabolism, improve lipid profiles, and lowers blood glucose without harmful side effects.
Read More
7.5
Hormonal balance
In the form of myo-inositol, it stabilises hormones and can lower "bad" cholesterol, thus reducing the risk of heart attack, stroke, hypertension, and cancer. It has also helped normalise my menstrual cycle.
Read More
7.5
Heart attack prevention
Just 4 grams of inositol a day can lower triglycerides and “bad” cholesterol by 20-30%, thus reducing the risk of heart attack, stroke, hypertension, and cancer. It also helps decrease insulin resistance and stabilise blood pressure.
Read More
Frequently Asked Questions
7.5
Hormonal balance
In the form of myo-inositol, it stabilises hormones and can lower "bad" cholesterol, thus reducing the risk of heart attack, stroke, hypertension, and cancer. It has also helped normalise my menstrual cycle.
7.5
Heart attack prevention
Just 4 grams of inositol a day can lower triglycerides and “bad” cholesterol by 20-30%, thus reducing the risk of heart attack, stroke, hypertension, and cancer. It also helps decrease insulin resistance and stabilise blood pressure.
7.5
Cholesterol reduction
Excellent! Just 4 grams of inositol each day can significantly lower triglycerides and “bad” cholesterol, reducing the risk of heart attack, stroke, hypertension, and cancer. It also aids in reducing insulin resistance.
9
Menstrual cycle restoration
Unbelievably, inositol has been instrumental in treating polycystic ovaries, aiding hormonal balance, stabilising the cardiovascular system, and prompting ovulation. It helps to lower triglycerides and reduces the risk of cancer.
7.5
Cancer risk reduction
Inositol, the most bioavailable form of vitamin B8, offers numerous benefits, such as reducing cancer risk. It helps normalise metabolism, improve lipid profiles, and lowers blood glucose without harmful side effects.
9
We investigated the potential benefits of Myo-inositol, a naturally occurring sugar alcohol, on DU-145 prostate cancer cells. By treating these cancer cells with various doses of Myo-inositol, we determined its half-maximal inhibitory concentration (IC50) using a simple method that measures cell viability.
Our findings revealed that Myo-inositol significantly decreased the viability of DU-145 cells, showing an IC50 of 0.06 mg/ml. This suggests that Myo-inositol may effectively inhibit cancer cell growth.
Furthermore, we performed a detailed proteomic analysis using advanced techniques to explore how Myo-inositol changes protein expression. We found notable differences in protein levels between treated and untreated cells, particularly in areas linked to key cellular functions like cytoskeletal regulation, apoptosis (cell death), and stress responses. For instance, certain proteins tied to tumor suppression were upregulated in response to Myo-inositol treatment.
Overall, these observations highlight Myo-inositol's potential as a therapeutic option. However, further studies are necessary to unravel the underlying mechanisms and assess its effectiveness in combination with other treatments for managing prostate cancer, especially castration-resistant prostate cancer (CRPC).
Our findings revealed that Myo-inositol significantly decreased the viability of DU-145 cells, showing an IC50 of 0.06 mg/ml. This suggests that Myo-inositol may effectively inhibit cancer cell growth.
Furthermore, we performed a detailed proteomic analysis using advanced techniques to explore how Myo-inositol changes protein expression. We found notable differences in protein levels between treated and untreated cells, particularly in areas linked to key cellular functions like cytoskeletal regulation, apoptosis (cell death), and stress responses. For instance, certain proteins tied to tumor suppression were upregulated in response to Myo-inositol treatment.
Overall, these observations highlight Myo-inositol's potential as a therapeutic option. However, further studies are necessary to unravel the underlying mechanisms and assess its effectiveness in combination with other treatments for managing prostate cancer, especially castration-resistant prostate cancer (CRPC).
7
Vitamin E Succinate enhances autophagy
We examined how vitamin E succinate (VES) affects autophagy in human gastric cancer cells by activating a calcium signaling pathway. Our study involved cultured gastric cancer cell lines treated with various doses of VES. We noted that VES significantly reduced cell proliferation and enhanced the formation of autophagosomes, indicating increased autophagy.
However, when we inhibited the calcium channel involved, the positive effects of VES diminished, suggesting the importance of this pathway in its action. Overall, while VES shows promise in promoting autophagy, further research is needed to understand its full potential in cancer treatment.
However, when we inhibited the calcium channel involved, the positive effects of VES diminished, suggesting the importance of this pathway in its action. Overall, while VES shows promise in promoting autophagy, further research is needed to understand its full potential in cancer treatment.
9
We investigated how isogarcinol (ISO) influences breast cancer cells and what mechanisms are at play. Through lab tests, we found that ISO at 13 μM effectively lowered cell growth and movement. In living subjects, doses of 5 to 15 mg/kg showed a significant reduction in tumor activity.
We observed that ISO achieves its tumor-suppressing effects by lowering the levels of a protein called methionyl-tRNA synthetase (MARS) and deactivating key pathways involved in cancer progression. These findings suggest ISO could be a valuable addition to breast cancer treatment strategies.
We observed that ISO achieves its tumor-suppressing effects by lowering the levels of a protein called methionyl-tRNA synthetase (MARS) and deactivating key pathways involved in cancer progression. These findings suggest ISO could be a valuable addition to breast cancer treatment strategies.
References
- Islam MJ, Muntaha S, Masum MM, Nowshin S, Salam S, et al. Proteomic Analysis of Anticancer Effect of Myo-inositol in Human Prostate Cancer (DU-145) Cell Line. Asian Pac J Cancer Prev. 2024;25:4447. doi:10.31557/APJCP.2024.25.12.4447
- Wen XY, Cao MM, Zhang ZY, Xie N, Wei ZY, et al. [The role of endoplasmic reticulum IP(3)R calcium channel in vitamin E succinate induced autophagy of human gastric cancer cell]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2025;43:180. doi:10.3760/cma.j.cn121094-20240125-00037
- Zhang D, Chu Y, Li M, Du L. Isogarcinol Reduces MARS Levels and Deactivates the PI3K/AKT Pathway to Suppress the Malignant Properties of Breast Cancer Cells. Cell Biochem Biophys. 2025. doi:10.1007/s12013-025-01727-0
