' 
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.7
USERS' SCORE
Good
Based on 1 Review
8.5
Supplement Facts
Serving Size: About 1/4 cup (31 g)
Amount Per Serving
%DV
Calories
180
Total Fat
13 g
17%
Saturated Fat
3 g
15%
Trans Fat
0 g
Cholesterol
0 mg
0%
Sodium
0 mg
0%
Total Carbohydrate
4 g
1%
Dietary Fiber
2 g
7%
Total Sugars
0 g
Includes 0g Added Sugars
0%
Protein
11g
Vit. D
0 mcg
0%
Calcium
8 mg
0%
Iron
4 mg
20%
Potassium
243 mg
6%
Top Medical Research Studies
9
Fermented pea protein improves sleep
Sleep-enhancing activity of fermented pea protein hydrolysate with enhanced GABA content by Lactobacillus brevis SYLB 0016 fermentation.
Direct focus on insomnia treatment.
We explored the potential of fermented pea protein hydrolysate, enriched with gamma-aminobutyric acid (GABA), to improve sleep. This intriguing study involved testing on ICR mice and Sprague Dawley rats, specifically looking at how this protein treatment could affect sleep duration and structure.
Our findings revealed that after fermentation by Lactobacillus brevis SYLB 0016, the GABA content increased significantly, which could be key in enhancing sleep quality. Notably, in tests where sleep was induced with pentobarbital, the hydrolysate extended sleep duration by an average of 25 minutes compared to the control group. Moreover, we found that the time spent in non-rapid eye movement (NREM) sleep increased, showing a boost in delta wave activity, which is important for restful sleep.
Further experiments indicated that the pea protein hydrolysate also benefited those suffering from caffeine-induced insomnia, effectively lengthening sleep periods at various dosages. Additionally, regular intake over three weeks improved GABA levels and receptor expression in the brain, which points towards a strong connection with sleep enhancement.
Overall, our research suggests that this hypoallergenic protein supplement holds promise for those struggling with sleep disorders. The findings support the idea that fermented pea protein could be a natural way to promote better sleep.
Our findings revealed that after fermentation by Lactobacillus brevis SYLB 0016, the GABA content increased significantly, which could be key in enhancing sleep quality. Notably, in tests where sleep was induced with pentobarbital, the hydrolysate extended sleep duration by an average of 25 minutes compared to the control group. Moreover, we found that the time spent in non-rapid eye movement (NREM) sleep increased, showing a boost in delta wave activity, which is important for restful sleep.
Further experiments indicated that the pea protein hydrolysate also benefited those suffering from caffeine-induced insomnia, effectively lengthening sleep periods at various dosages. Additionally, regular intake over three weeks improved GABA levels and receptor expression in the brain, which points towards a strong connection with sleep enhancement.
Overall, our research suggests that this hypoallergenic protein supplement holds promise for those struggling with sleep disorders. The findings support the idea that fermented pea protein could be a natural way to promote better sleep.
Read More
8
Insomnia linked to specific proteins
Characterizing Genetic-Predisposed Proteins Involving Insomnia by Integrating Genome-Wide Association Study Summary Statistics.
Moderate relevance due to complexities
We investigated how certain proteins might influence the risk of insomnia. Through extensive analyses, including integrative studies involving genome-wide association studies (GWAS), we found that changes in protein levels related to 28 specific genes in the brain were associated with insomnia risk.
In our research, we identified four proteins—ADO, CAMLG, ICA1L, and LXN—that appeared to play significant roles. Interestingly, we discovered that higher levels of ADO, CAMLG, and ICA1L corresponded to a lower risk of developing insomnia. Conversely, a higher level of LXN was linked to an increased risk of insomnia.
Additionally, we explored how genetically predicted insomnia might relate to other health issues. Our findings indicated a potential increase in the risk for cardiovascular diseases and depression associated with insomnia. Overall, this study sheds light on the potential for these proteins to inform further research into treatment options and the biological mechanisms behind insomnia.
In our research, we identified four proteins—ADO, CAMLG, ICA1L, and LXN—that appeared to play significant roles. Interestingly, we discovered that higher levels of ADO, CAMLG, and ICA1L corresponded to a lower risk of developing insomnia. Conversely, a higher level of LXN was linked to an increased risk of insomnia.
Additionally, we explored how genetically predicted insomnia might relate to other health issues. Our findings indicated a potential increase in the risk for cardiovascular diseases and depression associated with insomnia. Overall, this study sheds light on the potential for these proteins to inform further research into treatment options and the biological mechanisms behind insomnia.
Read More
9
Microneedles enhance melatonin delivery
Silk fibroin microneedles loaded with melatonin for circadian rhythm regulation.
Focus on melatonin delivery
We investigated the potential of silk fibroin microneedles as a novel way to deliver melatonin, a hormone that regulates sleep, to help with insomnia. In our research, the microneedles were designed to release melatonin gradually, improving how the body absorbs the drug and enhancing patient comfort.
The silk fibroin used in these microneedles creates a strong yet flexible structure that allows them to pierce the skin easily while forming a sustained-release channel. Our findings indicated that microneedles with a melatonin loading of 1 mg could release the hormone over 11 hours, with an impressive cumulative release rate of over 85%. This approach appears to be quite effective, as our animal studies demonstrated that these microneedles maintained stable melatonin levels in the bloodstream for up to 8 hours.
Critically, we observed significant positive effects on insomnia in animal models. The microneedles showed promise in correcting disrupted circadian rhythms and reducing anxiety, suggesting that melatonin delivered this way could be beneficial for those struggling with sleep issues. Overall, while the study highlights how microneedles laden with melatonin could assist with insomnia, it doesn't directly evaluate the effects of protein by itself in treating sleep disorders.
The silk fibroin used in these microneedles creates a strong yet flexible structure that allows them to pierce the skin easily while forming a sustained-release channel. Our findings indicated that microneedles with a melatonin loading of 1 mg could release the hormone over 11 hours, with an impressive cumulative release rate of over 85%. This approach appears to be quite effective, as our animal studies demonstrated that these microneedles maintained stable melatonin levels in the bloodstream for up to 8 hours.
Critically, we observed significant positive effects on insomnia in animal models. The microneedles showed promise in correcting disrupted circadian rhythms and reducing anxiety, suggesting that melatonin delivered this way could be beneficial for those struggling with sleep issues. Overall, while the study highlights how microneedles laden with melatonin could assist with insomnia, it doesn't directly evaluate the effects of protein by itself in treating sleep disorders.
Read More
Most Useful Reviews
8.8
Alleviates insomnia
This product significantly helped with my stomach issues and psychological state. I noticed a positive change. The taste is quite sweet, and it’s particularly beneficial for those suffering from insomnia, as it contains magnesium that aids relaxation during sleep.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.7
9
Fermented pea protein improves sleep
Sleep-enhancing activity of fermented pea protein hydrolysate with enhanced GABA content by Lactobacillus brevis SYLB 0016 fermentation.
Direct focus on insomnia treatment.
We explored the potential of fermented pea protein hydrolysate, enriched with gamma-aminobutyric acid (GABA), to improve sleep. This intriguing study involved testing on ICR mice and Sprague Dawley rats, specifically looking at how this protein treatment could affect sleep duration and structure.
Our findings revealed that after fermentation by Lactobacillus brevis SYLB 0016, the GABA content increased significantly, which could be key in enhancing sleep quality. Notably, in tests where sleep was induced with pentobarbital, the hydrolysate extended sleep duration by an average of 25 minutes compared to the control group. Moreover, we found that the time spent in non-rapid eye movement (NREM) sleep increased, showing a boost in delta wave activity, which is important for restful sleep.
Further experiments indicated that the pea protein hydrolysate also benefited those suffering from caffeine-induced insomnia, effectively lengthening sleep periods at various dosages. Additionally, regular intake over three weeks improved GABA levels and receptor expression in the brain, which points towards a strong connection with sleep enhancement.
Overall, our research suggests that this hypoallergenic protein supplement holds promise for those struggling with sleep disorders. The findings support the idea that fermented pea protein could be a natural way to promote better sleep.
Our findings revealed that after fermentation by Lactobacillus brevis SYLB 0016, the GABA content increased significantly, which could be key in enhancing sleep quality. Notably, in tests where sleep was induced with pentobarbital, the hydrolysate extended sleep duration by an average of 25 minutes compared to the control group. Moreover, we found that the time spent in non-rapid eye movement (NREM) sleep increased, showing a boost in delta wave activity, which is important for restful sleep.
Further experiments indicated that the pea protein hydrolysate also benefited those suffering from caffeine-induced insomnia, effectively lengthening sleep periods at various dosages. Additionally, regular intake over three weeks improved GABA levels and receptor expression in the brain, which points towards a strong connection with sleep enhancement.
Overall, our research suggests that this hypoallergenic protein supplement holds promise for those struggling with sleep disorders. The findings support the idea that fermented pea protein could be a natural way to promote better sleep.
Read More
9
Microneedles enhance melatonin delivery
Silk fibroin microneedles loaded with melatonin for circadian rhythm regulation.
Focus on melatonin delivery
We investigated the potential of silk fibroin microneedles as a novel way to deliver melatonin, a hormone that regulates sleep, to help with insomnia. In our research, the microneedles were designed to release melatonin gradually, improving how the body absorbs the drug and enhancing patient comfort.
The silk fibroin used in these microneedles creates a strong yet flexible structure that allows them to pierce the skin easily while forming a sustained-release channel. Our findings indicated that microneedles with a melatonin loading of 1 mg could release the hormone over 11 hours, with an impressive cumulative release rate of over 85%. This approach appears to be quite effective, as our animal studies demonstrated that these microneedles maintained stable melatonin levels in the bloodstream for up to 8 hours.
Critically, we observed significant positive effects on insomnia in animal models. The microneedles showed promise in correcting disrupted circadian rhythms and reducing anxiety, suggesting that melatonin delivered this way could be beneficial for those struggling with sleep issues. Overall, while the study highlights how microneedles laden with melatonin could assist with insomnia, it doesn't directly evaluate the effects of protein by itself in treating sleep disorders.
The silk fibroin used in these microneedles creates a strong yet flexible structure that allows them to pierce the skin easily while forming a sustained-release channel. Our findings indicated that microneedles with a melatonin loading of 1 mg could release the hormone over 11 hours, with an impressive cumulative release rate of over 85%. This approach appears to be quite effective, as our animal studies demonstrated that these microneedles maintained stable melatonin levels in the bloodstream for up to 8 hours.
Critically, we observed significant positive effects on insomnia in animal models. The microneedles showed promise in correcting disrupted circadian rhythms and reducing anxiety, suggesting that melatonin delivered this way could be beneficial for those struggling with sleep issues. Overall, while the study highlights how microneedles laden with melatonin could assist with insomnia, it doesn't directly evaluate the effects of protein by itself in treating sleep disorders.
Read More
8
Insomnia linked to specific proteins
Characterizing Genetic-Predisposed Proteins Involving Insomnia by Integrating Genome-Wide Association Study Summary Statistics.
Moderate relevance due to complexities
We investigated how certain proteins might influence the risk of insomnia. Through extensive analyses, including integrative studies involving genome-wide association studies (GWAS), we found that changes in protein levels related to 28 specific genes in the brain were associated with insomnia risk.
In our research, we identified four proteins—ADO, CAMLG, ICA1L, and LXN—that appeared to play significant roles. Interestingly, we discovered that higher levels of ADO, CAMLG, and ICA1L corresponded to a lower risk of developing insomnia. Conversely, a higher level of LXN was linked to an increased risk of insomnia.
Additionally, we explored how genetically predicted insomnia might relate to other health issues. Our findings indicated a potential increase in the risk for cardiovascular diseases and depression associated with insomnia. Overall, this study sheds light on the potential for these proteins to inform further research into treatment options and the biological mechanisms behind insomnia.
In our research, we identified four proteins—ADO, CAMLG, ICA1L, and LXN—that appeared to play significant roles. Interestingly, we discovered that higher levels of ADO, CAMLG, and ICA1L corresponded to a lower risk of developing insomnia. Conversely, a higher level of LXN was linked to an increased risk of insomnia.
Additionally, we explored how genetically predicted insomnia might relate to other health issues. Our findings indicated a potential increase in the risk for cardiovascular diseases and depression associated with insomnia. Overall, this study sheds light on the potential for these proteins to inform further research into treatment options and the biological mechanisms behind insomnia.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.5
8.8
Alleviates insomnia
This product significantly helped with my stomach issues and psychological state. I noticed a positive change. The taste is quite sweet, and it’s particularly beneficial for those suffering from insomnia, as it contains magnesium that aids relaxation during sleep.
