Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
USERS' SCORE
Good
Based on 4 Reviews
8.4
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Glutathione (Reduced Form)
500 mg
**
Milk Thistle Extract (Silybum marianum) (Fruit/Seeds) (Standardized to 80 mg Silymarin Flavonoids - equivalent 80%)
100 mg
**
Alpha Lipoic Acid
50 mg
**
Top Medical Research Studies
9
Milk thistle shows anti-psoriatic effects
We investigated how milk thistle extract might help treat psoriasis in mice. Our study involved forty Swiss albino mice divided into four groups, including a test group treated with the milk thistle extract after inducing psoriasis with imiquimod.
The results were encouraging, showing that the extract significantly reduced skin symptoms like redness and scaling, similar to traditional cortisone treatments. It worked by inhibiting specific cellular pathways, reducing inflammation and boosting antioxidant defenses, suggesting that milk thistle could be an effective new option for psoriasis treatment.
The results were encouraging, showing that the extract significantly reduced skin symptoms like redness and scaling, similar to traditional cortisone treatments. It worked by inhibiting specific cellular pathways, reducing inflammation and boosting antioxidant defenses, suggesting that milk thistle could be an effective new option for psoriasis treatment.
Read More
8
We investigated the effects of silymarin, a natural compound from milk thistle, on psoriasis in a mouse model. Employing a robust approach that evaluated specific signaling pathways, we found that silymarin significantly targets the TGF-β1/miR-21 pathway.
This treatment not only blocked harmful cell cycle progression and reduced keratinocyte differentiation but also alleviated inflammation. Our findings suggest that silymarin promotes healthier skin by regulating lipid synthesis and inflammatory responses, pointing to its potential as a supportive therapy for psoriasis.
This treatment not only blocked harmful cell cycle progression and reduced keratinocyte differentiation but also alleviated inflammation. Our findings suggest that silymarin promotes healthier skin by regulating lipid synthesis and inflammatory responses, pointing to its potential as a supportive therapy for psoriasis.
Read More
Most Useful Reviews
9
Notable improvement
After a month of taking it, I have noticed an improvement in my psoriasis and my skin overall. Including it in my diet, particularly with my alcohol consumption, helps my liver, as I no longer feel fatigued all the time, considering my age. It is of good quality.
Read More
9
Effective treatment
Excellent for treating psoriasis.
Read More
7.5
Improved wellbeing
Glutathione possesses truly unique properties: it reacts with free radicals, converting them into harmless metabolic products; neutralises poisons and toxins, removing them from the body; restores antioxidants like vitamins A, E, and C; and aids in nerve impulse transmission. It can enhance the condition of individuals with Alzheimer's and Parkinson's, acting as a protective buffer for brain cells, thereby preserving mental clarity and memory even in old age. It also plays a role in immune defence, binding antigen-antibody complexes for destruction by killer cells. An excellent supplement that I always order for my brother-in-law, who has psoriasis. He states he feels better when using this supplement.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
- All Researches
9
Milk thistle shows anti-psoriatic effects
We investigated how milk thistle extract might help treat psoriasis in mice. Our study involved forty Swiss albino mice divided into four groups, including a test group treated with the milk thistle extract after inducing psoriasis with imiquimod.
The results were encouraging, showing that the extract significantly reduced skin symptoms like redness and scaling, similar to traditional cortisone treatments. It worked by inhibiting specific cellular pathways, reducing inflammation and boosting antioxidant defenses, suggesting that milk thistle could be an effective new option for psoriasis treatment.
The results were encouraging, showing that the extract significantly reduced skin symptoms like redness and scaling, similar to traditional cortisone treatments. It worked by inhibiting specific cellular pathways, reducing inflammation and boosting antioxidant defenses, suggesting that milk thistle could be an effective new option for psoriasis treatment.
Read More
8
We investigated the effects of silymarin, a natural compound from milk thistle, on psoriasis in a mouse model. Employing a robust approach that evaluated specific signaling pathways, we found that silymarin significantly targets the TGF-β1/miR-21 pathway.
This treatment not only blocked harmful cell cycle progression and reduced keratinocyte differentiation but also alleviated inflammation. Our findings suggest that silymarin promotes healthier skin by regulating lipid synthesis and inflammatory responses, pointing to its potential as a supportive therapy for psoriasis.
This treatment not only blocked harmful cell cycle progression and reduced keratinocyte differentiation but also alleviated inflammation. Our findings suggest that silymarin promotes healthier skin by regulating lipid synthesis and inflammatory responses, pointing to its potential as a supportive therapy for psoriasis.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Notable improvement
After a month of taking it, I have noticed an improvement in my psoriasis and my skin overall. Including it in my diet, particularly with my alcohol consumption, helps my liver, as I no longer feel fatigued all the time, considering my age. It is of good quality.
Read More
9
Effective treatment
Excellent for treating psoriasis.
Read More
7.5
Improved wellbeing
Glutathione possesses truly unique properties: it reacts with free radicals, converting them into harmless metabolic products; neutralises poisons and toxins, removing them from the body; restores antioxidants like vitamins A, E, and C; and aids in nerve impulse transmission. It can enhance the condition of individuals with Alzheimer's and Parkinson's, acting as a protective buffer for brain cells, thereby preserving mental clarity and memory even in old age. It also plays a role in immune defence, binding antigen-antibody complexes for destruction by killer cells. An excellent supplement that I always order for my brother-in-law, who has psoriasis. He states he feels better when using this supplement.
Read More
7.5
Boosted immunity
I started using it as a supplement to boost my immunity and also to alleviate my psoriasis.
Read More
Frequently Asked Questions
9
Notable improvement
After a month of taking it, I have noticed an improvement in my psoriasis and my skin overall. Including it in my diet, particularly with my alcohol consumption, helps my liver, as I no longer feel fatigued all the time, considering my age. It is of good quality.
9
Effective treatment
Excellent for treating psoriasis.
7.5
Improved wellbeing
Glutathione possesses truly unique properties: it reacts with free radicals, converting them into harmless metabolic products; neutralises poisons and toxins, removing them from the body; restores antioxidants like vitamins A, E, and C; and aids in nerve impulse transmission. It can enhance the condition of individuals with Alzheimer's and Parkinson's, acting as a protective buffer for brain cells, thereby preserving mental clarity and memory even in old age. It also plays a role in immune defence, binding antigen-antibody complexes for destruction by killer cells. An excellent supplement that I always order for my brother-in-law, who has psoriasis. He states he feels better when using this supplement.
7.5
Boosted immunity
I started using it as a supplement to boost my immunity and also to alleviate my psoriasis.
9
Milk thistle shows anti-psoriatic effects
We investigated how milk thistle extract might help treat psoriasis in mice. Our study involved forty Swiss albino mice divided into four groups, including a test group treated with the milk thistle extract after inducing psoriasis with imiquimod.
The results were encouraging, showing that the extract significantly reduced skin symptoms like redness and scaling, similar to traditional cortisone treatments. It worked by inhibiting specific cellular pathways, reducing inflammation and boosting antioxidant defenses, suggesting that milk thistle could be an effective new option for psoriasis treatment.
The results were encouraging, showing that the extract significantly reduced skin symptoms like redness and scaling, similar to traditional cortisone treatments. It worked by inhibiting specific cellular pathways, reducing inflammation and boosting antioxidant defenses, suggesting that milk thistle could be an effective new option for psoriasis treatment.
8
We investigated the effects of silymarin, a natural compound from milk thistle, on psoriasis in a mouse model. Employing a robust approach that evaluated specific signaling pathways, we found that silymarin significantly targets the TGF-β1/miR-21 pathway.
This treatment not only blocked harmful cell cycle progression and reduced keratinocyte differentiation but also alleviated inflammation. Our findings suggest that silymarin promotes healthier skin by regulating lipid synthesis and inflammatory responses, pointing to its potential as a supportive therapy for psoriasis.
This treatment not only blocked harmful cell cycle progression and reduced keratinocyte differentiation but also alleviated inflammation. Our findings suggest that silymarin promotes healthier skin by regulating lipid synthesis and inflammatory responses, pointing to its potential as a supportive therapy for psoriasis.
References
- Kamel NM, El-Sayed SS, El-Said YAM, El-Kersh DM, Hashem MM, et al. Unlocking milk thistle's anti-psoriatic potential in mice: Targeting PI3K/AKT/mTOR and KEAP1/NRF2/NF-κB pathways to modulate inflammation and oxidative stress. Int Immunopharmacol. 2024;139:112781. 10.1016/j.intimp.2024.112781
- Henriet E, Abdallah F, Laurent Y, Guimpied C, Clement E, et al. Targeting TGF-β1/miR-21 Pathway in Keratinocytes Reveals Protective Effects of Silymarin on Imiquimod-Induced Psoriasis Mouse Model. JID Innov. 2023;3:100175. 10.1016/j.xjidi.2022.100175
