Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 29 Researches
7.6
USERS' SCORE
Good
Based on 82 Reviews
8.3
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Iron (elemental) (from 90 mg Ferrous Bisglycinate)(Ferrochel™)
18 mg
100%

Top Medical Research Studies

We examined how iron treatment specifically impacts anemia, particularly during pregnancy. Iron deficiency is a leading cause of anemia, and finding the right treatment is crucial for both mothers and their developing babies.

Our study focused on just the effects of iron without looking at other treatments. This clear approach allowed us to isolate the benefits of iron supplementation. The results were insightful, showing that iron treatment had measurable effects on reducing anemia.

However, we must be careful about overgeneralizing these findings. While our results indicate improvements, it's important to recognize that individual responses to iron may vary. Our findings highlight the importance of monitoring iron levels in pregnant women to effectively address anemia.
Read More
8
Iron treatment and CKD anemia
We explored the critical relationship between iron treatment and anemia in chronic kidney disease (CKD). Anemia often arises in CKD patients, whether they are on dialysis or not, primarily due to erythropoietin deficiency. However, iron deficiency plays a significant role and can be categorized into absolute, caused by blood loss, or functional, which is affected by inflammation and high levels of hepcidin.

Hepcidin impedes the body’s ability to use iron effectively, trapping it where it's not accessible for red blood cell production. This disruption in iron metabolism also means that oral iron supplements may not work well, especially in advanced CKD. Therefore, we reviewed various intravenous (IV) iron formulations available for treatment and outlined the diagnostic criteria and treatment benchmarks for iron deficiency in CKD patients.

Our findings led us to consider future therapeutic directions to improve patient outcomes. With advancements in the understanding of iron’s role in this context, the hope is to enhance treatment strategies for managing anemia in CKD effectively.
Read More
8
Ferric Carboxymaltose Replaces Iron Sucrose
We aimed to find a better way to manage anemia in pediatric patients undergoing hemodialysis. Traditionally, these patients receive intravenous (IV) iron therapy using iron sucrose, which requires frequent treatments and carries a risk of allergic reactions. Moving forward with a home hemodialysis program, we investigated ferric carboxymaltose as a safer and more effective alternative.

In our study, we looked closely at how ferric carboxymaltose performed in maintaining healthy levels of hemoglobin, transferrin saturation, and reticulocyte hemoglobin content over a 12-month period. We also compared its efficacy against traditional iron sucrose treatments. The results were encouraging, showing that ferric carboxymaltose not only matched the effectiveness of iron sucrose but also required fewer hospital visits, significantly easing the treatment burden on families.

Overall, our findings suggest that ferric carboxymaltose is both clinically effective and cost-efficient. By reducing the frequency of administration, this approach can enhance the quality of life for pediatric patients with anemia due to chronic kidney disease who depend on hemodialysis. We believe this innovation presents a promising shift in anemia management for this vulnerable population.
Read More

Most Useful Reviews

9
Natural alternative work
289 people found this helpful
Worked well Alone and With Ferret's Iron. In early 2013, I had low iron affecting my hair health. After struggling with prescription iron due to severe side effects, I researched alternatives and found these pills. Taking them before a blood test, I experienced no stomach issues, and my blood test revealed my iron levels improved significantly. I now take these along with Ferrett's Iron Supplement and I'm delighted with my progress. They are a big help in building my iron levels.
Read More
9
Significant improvement noted
65 people found this helpful
This product is fantastic! I managed to raise my haemoglobin from 121 (mild anaemia) to 159 g/l over a couple of months by taking one capsule daily. For better absorption, I recommend taking iron alongside vitamin C and keeping it separate from tea, coffee, and milk. I wish everyone good health and vitality!
Read More
10
Increased iron levels
29 people found this helpful
I highly recommend this product for anyone suffering from iron deficiency anemia. My iron levels significantly improved, rising to 117 within a month, from a previous 70-80. It's essential for patients with low iron; I suggest buying it immediately.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 29 Researches
7.6
  • All Researches
We examined how iron treatment specifically impacts anemia, particularly during pregnancy. Iron deficiency is a leading cause of anemia, and finding the right treatment is crucial for both mothers and their developing babies.

Our study focused on just the effects of iron without looking at other treatments. This clear approach allowed us to isolate the benefits of iron supplementation. The results were insightful, showing that iron treatment had measurable effects on reducing anemia.

However, we must be careful about overgeneralizing these findings. While our results indicate improvements, it's important to recognize that individual responses to iron may vary. Our findings highlight the importance of monitoring iron levels in pregnant women to effectively address anemia.
Read More
9.5
Identifying and treating hookworm infection
We explored the challenges of diagnosing hookworm infections, particularly in severe cases. By using both morphological and molecular methods, we successfully identified a 75-year-old woman suffering from anemia linked to the hookworm species, Necator americanus. After confirming the infection through various tests, we initiated treatment with albendazole. Following this, we observed a significant improvement in her condition, with both the hookworm and her anemia effectively resolved.
Read More
9
Iron supplementation effects on anemia
We explored the impact of iron and folic acid supplementation on children suffering from mild-to-moderate anemia in India. This study specifically aimed to assess how effective iron treatments are in improving overall hemoglobin levels and reducing anemia symptoms.

The research consisted of controlled trials where groups of children received iron supplements, while others did not. By comparing these groups, we aimed to determine if there was a significant difference in the rates of recovery from anemia.

While we hoped for positive outcomes from the supplementation, the findings showed mixed results. In some cases, we observed improvements in hemoglobin levels, but the overall effectiveness was not as pronounced as anticipated. It's essential to take these findings into account when considering future strategies for combating anemia in children.

Our analysis highlights that while iron supplementation is a crucial piece of the puzzle for treating anemia, it’s also clear that additional factors may play significant roles in achieving optimal health outcomes for affected children.
Read More
9
Serum hepcidin aids anemia diagnosis
We explored the effectiveness of serum hepcidin levels in diagnosing types of anemia in elderly patients, specifically focusing on iron deficiency anemia (IDA) and anemia of chronic disease (ACD). By studying a group of 100 elderly patients alongside 15 healthy controls, we aimed to find a less invasive way to distinguish between these two common conditions.

Through our evaluation, we observed significant differences in iron levels and hepcidin concentrations between patients with IDA and those with ACD. We discovered that serum hepcidin could effectively differentiate between the two types of anemia, boasting a remarkable sensitivity of 93.9% and a specificity of 92.2%. This points to hepcidin as a promising alternative to the traditional bone marrow iron study.

Interestingly, while hepcidin is a valuable marker, relying solely on it can lead to misdiagnoses, similar concerns arise with ferritin levels. Our findings suggest that combining hepcidin with the iron profile provides a more accurate assessment and could potentially replace more invasive diagnostic methods for anemia in the elderly. Overall, we find this combined approach to be a vital step forward in understanding and treating anemia related to iron levels.
Read More
We investigated the combination of Roxadustat, a newer treatment for anemia related to chronic kidney disease (CKD), alongside polysaccharide-iron complex (PIC) in rats. By dividing them into different groups, we observed how various doses of iron impacted hemoglobin levels and kidney function. The results showed that this combination significantly improved hemoglobin levels and kidney health. Importantly, adequate iron supply early on was crucial for effective anemia treatment. Combining these therapies appears beneficial in addressing anemia in CKD effectively.
Read More

User Reviews

USERS' SCORE
Good
Based on 82 Reviews
8.3
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Natural alternative work
289 people found this helpful
Worked well Alone and With Ferret's Iron. In early 2013, I had low iron affecting my hair health. After struggling with prescription iron due to severe side effects, I researched alternatives and found these pills. Taking them before a blood test, I experienced no stomach issues, and my blood test revealed my iron levels improved significantly. I now take these along with Ferrett's Iron Supplement and I'm delighted with my progress. They are a big help in building my iron levels.
Read More
9
Significant improvement noted
65 people found this helpful
This product is fantastic! I managed to raise my haemoglobin from 121 (mild anaemia) to 159 g/l over a couple of months by taking one capsule daily. For better absorption, I recommend taking iron alongside vitamin C and keeping it separate from tea, coffee, and milk. I wish everyone good health and vitality!
Read More
10
Increased iron levels
29 people found this helpful
I highly recommend this product for anyone suffering from iron deficiency anemia. My iron levels significantly improved, rising to 117 within a month, from a previous 70-80. It's essential for patients with low iron; I suggest buying it immediately.
Read More
10
Improved quality of life
17 people found this helpful
Best Iron Pills. As a woman with moderate to severe iron deficiency anemia for years, these pills have been a God-send. I've been taking one each morning for a month, and my energy levels and quality of life have significantly improved. No longer feeling cold and clammy, I have all-day energy without relying on coffee. I no longer feel fatigued or lethargic. Menstrual cycles no longer leave me wiped out. I was skeptical at first, but I'm so glad I tried these. Absolutely no side effects for me.
Read More
9
Effective for pregnancy
15 people found this helpful
We managed to resolve my anaemia during pregnancy after an eight-month struggle. Initially, my haemoglobin was at 10.3 and I was prescribed iron, but I faced side effects and didn’t take it completely. After taking Perfect Prenatal and New Chapter supplements daily, my haemoglobin rose to 12.6 after eight weeks.
Read More

Frequently Asked Questions

10
Significant effect
8 people found this helpful
After supplementing with iron for 40 days, the improvement has been extraordinary! My hemoglobin levels rose from 75 to 105, something I struggled to achieve with other methods. Those with iron deficiency anemia should definitely try this.
10
Muscle cramps resolved
3 people found this helpful
My anaemia has disappeared after 1.5 weeks of taking this supplement; my muscles no longer cramp.
9
Effective for pregnancy
15 people found this helpful
We managed to resolve my anaemia during pregnancy after an eight-month struggle. Initially, my haemoglobin was at 10.3 and I was prescribed iron, but I faced side effects and didn’t take it completely. After taking Perfect Prenatal and New Chapter supplements daily, my haemoglobin rose to 12.6 after eight weeks.
9
Significant improvement noted
65 people found this helpful
This product is fantastic! I managed to raise my haemoglobin from 121 (mild anaemia) to 159 g/l over a couple of months by taking one capsule daily. For better absorption, I recommend taking iron alongside vitamin C and keeping it separate from tea, coffee, and milk. I wish everyone good health and vitality!
10
Increased iron levels
29 people found this helpful
I highly recommend this product for anyone suffering from iron deficiency anemia. My iron levels significantly improved, rising to 117 within a month, from a previous 70-80. It's essential for patients with low iron; I suggest buying it immediately.
9
Enhanced concentration
10 people found this helpful
Initially anemic from uterine fibroids, my condition impacted my daily life. With iron supplements, my anemia has improved significantly, allowing me to concentrate better and feel revitalised. I will continue this treatment until my iron stores improve fully.
9
Boosted energy during pregnancy
8 people found this helpful
To cope with anemia during my pregnancy planning, I took iron daily as advised by my hematologist. I increased the dose to 36mg twice a day and felt better immediately, with enough strength to manage daily tasks until birth. Iron works wonders, especially when paired with vitamin C.
9
No stomach issues
1 people found this helpful
I was informed at the hospital that I had anemia and began taking this along with vitamin C and vitamin B. My anemia has improved. Unlike some iron preparations that cause stomach upset, this one does not. The quality is good, allowing me to take it confidently.
7.5
More energy
5 people found this helpful
The dosage is fantastic! The larger one made me feel ill, so I switched to 18 mg, having found that 36 mg caused sickness right from the start, even with vitamin C. These capsules are a saviour! I take one during the day with ascorbic acid and another in the evening. There’s no overload or side effects. I prefer this iron from Nou over Solgar. It’s made me feel stronger, more energetic and less shaky outside, all great effects of treating my anemia.
8
Ferric Carboxymaltose Replaces Iron Sucrose
We aimed to find a better way to manage anemia in pediatric patients undergoing hemodialysis. Traditionally, these patients receive intravenous (IV) iron therapy using iron sucrose, which requires frequent treatments and carries a risk of allergic reactions. Moving forward with a home hemodialysis program, we investigated ferric carboxymaltose as a safer and more effective alternative.

In our study, we looked closely at how ferric carboxymaltose performed in maintaining healthy levels of hemoglobin, transferrin saturation, and reticulocyte hemoglobin content over a 12-month period. We also compared its efficacy against traditional iron sucrose treatments. The results were encouraging, showing that ferric carboxymaltose not only matched the effectiveness of iron sucrose but also required fewer hospital visits, significantly easing the treatment burden on families.

Overall, our findings suggest that ferric carboxymaltose is both clinically effective and cost-efficient. By reducing the frequency of administration, this approach can enhance the quality of life for pediatric patients with anemia due to chronic kidney disease who depend on hemodialysis. We believe this innovation presents a promising shift in anemia management for this vulnerable population.
We explored the impact of ferric carboxymaltose (FCM) on iron deficiency anemia (IDA) in patients with inflammatory bowel disease (IBD) through a thorough retrospective study involving 41 individuals. We observed that hemoglobin levels significantly increased from 9.8 g/dL to 11.8 g/dL in just 16 weeks after treatment. However, the gains in hemoglobin were similar for patients regardless of inflammation levels. While some adverse effects were recorded, they were relatively rare. Overall, FCM shows promise for treating anemia in IBD with fewer applications needed.
4
Iron supplementation alone sufficient
We set out to understand how iron supplementation affects anemia in children by comparing the effects of iron-folic acid with and without additional multiple micronutrients. Conducted as a randomized controlled trial in rural Haryana, India, we included children aged 6 to 59 months with mild to moderate anemia.

Participants were divided into two groups: one received daily iron and folic acid along with multiple micronutrients, while the other was given just iron and folic acid for 90 days. Our aim was to evaluate changes in hemoglobin levels and the rate of recovery from anemia at the end of the study.

After tracking 1,300 children, we found that there was no significant difference in the effectiveness of the two treatments regarding hemoglobin concentration or the proportion of children who were cured of anemia. In fact, compliance with the treatment was high in both groups, but additional micronutrients did not lead to improved outcomes compared to iron and folic acid alone.

Ultimately, our findings suggest that focusing on ensuring children get their necessary iron and folic acid could effectively address anemia, without the need for extra micronutrients.
We examined how iron treatment specifically impacts anemia, particularly during pregnancy. Iron deficiency is a leading cause of anemia, and finding the right treatment is crucial for both mothers and their developing babies.

Our study focused on just the effects of iron without looking at other treatments. This clear approach allowed us to isolate the benefits of iron supplementation. The results were insightful, showing that iron treatment had measurable effects on reducing anemia.

However, we must be careful about overgeneralizing these findings. While our results indicate improvements, it's important to recognize that individual responses to iron may vary. Our findings highlight the importance of monitoring iron levels in pregnant women to effectively address anemia.
7
IV Iron Treatment's Limited Effectiveness
We evaluated the effectiveness of intravenous iron, specifically ferric derisomaltose, in treating iron deficiency with or without anemia in nearly 2,500 patients. The study revealed that while hemoglobin levels improved significantly, over 65% of patients remained anemic after treatment.

Our findings highlighted that the mean dose of iron administered fell short of the estimated need, suggesting many patients may not receive enough iron. Although only one serious allergic reaction was reported, the results emphasize the necessity of optimizing treatment doses for better outcomes.
8
Effective iron treatment for anemia
We examined how well low-dose ferric carboxymaltose (FCM) works compared to oral ferrous sulfate for treating anemia in postpartum East Asian women. In a randomized controlled trial, we found that FCM led to a bigger boost in hemoglobin levels after two weeks and improved iron stores at four weeks.

While the overall hemoglobin increase was similar at four weeks, FCM users reported fewer gastrointestinal side effects, like nausea and constipation. This suggests that low-dose FCM could be a better choice for managing postpartum anemia due to its effectiveness and better tolerance.

References

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  2. Upadhyay RP, Chowdhury R, Mundra S, Taneja S, Jacob M, et al. Comparative effectiveness of daily therapeutic supplementation with multiple micronutrients and iron-folic acid versus iron-folic acid alone in children with mild-to-moderate anaemia in rural India: an open-label, randomised controlled trial. Lancet Glob Health. 2025;13:e497. doi:10.1016/S2214-109X(24)00559-X
  3. Thomas T, Kurpad A. Childhood iron-folic acid supplementation in India for mild-to-moderate anaemia. Lancet Glob Health. 2025;13:e383. doi:10.1016/S2214-109X(25)00053-1
  4. Babah OA, Beňová L, Larsson EC, Hanson C, Afolabi BB. Is an improvement in anaemia and iron levels associated with the risk of early postpartum depression? A cohort study from Lagos, Nigeria. BMC Public Health. 2025;25:808. doi:10.1186/s12889-025-21942-x
  5. Crispell EH, Cassianni CE, Burt JM, Gonzalez JA, Petsch JL, et al. Design and Staged Implementation of a Multidisciplinary Preoperative Anemia Clinic at a Tertiary Care Medical Center. Anesth Analg. 2025. doi:10.1213/ANE.0000000000007435
  6. Akpan IJ, Narang M, Zampaglione E, Marshall S, Stefanik D. Iron deficiency anemia in patients with heavy menstrual bleeding: The patients' perspective from diagnosis to treatment. Womens Health (Lond). 2025;21:17455057251321221. doi:10.1177/17455057251321221
  7. Khalaf K, Fujiyoshi Y, Bechara R. Endoscopic and clinical characteristics of autoimmune atrophic gastritis: Retrospective study. Endosc Int Open. 2025;13:a24774666. doi:10.1055/a-2477-4666
  8. White F, Polakowski N, Merlington E, Leimanis M, Dudick B, et al. Intravenous Sodium Ferric Gluconate Complex for Hospitalized Pediatric Patients with Iron Deficiency Anemia. Children (Basel). 2025;12. doi:10.3390/children12020189
  9. Maidana D, Arroyo-Álvarez A, Barreres-Martín G, Arenas-Loriente A, Cepas-Guillen P, et al. Targeting Inflammation and Iron Deficiency in Heart Failure: A Focus on Older Adults. Biomedicines. 2025;13. doi:10.3390/biomedicines13020462
  10. McDonnell T, Kalra PA. Iron in Chronic Kidney Disease and End-Stage Kidney Disease-Current Trends and Future Direction. Br J Hosp Med (Lond). 2025;86:1. doi:10.12968/hmed.2024.0619
  11. Orlova P, Meshkov I, Sharikov S, Frolov V, Skuredina A, et al. Amidated and Aminated PMSSO-Hydrogels as a Promising Enzyme-Sensitive Vehicle for Antianemic Drugs. Gels. 2025;11. doi:10.3390/gels11020118
  12. Al Kindi S, Al-Mamari A, Al-Zadjali S, Al-Rawahi M, Al Madhani A, et al. Case report: A novel 11-bp deletion in exon 11 causing a frameshift in the C-terminal of the gene leading to X-linked sideroblastic anemia-a family study. Front Med (Lausanne). 2024;11:1452873. doi:10.3389/fmed.2024.1452873
  13. Manna S, Chakrabarti SS, Singh R, Gambhir IS. Serum hepcidin level with iron profile assay might replace bone marrow iron study as a diagnostic tool for evaluation of anemia in elderly without chronic renal disease. J Family Med Prim Care. 2025;14:356. doi:10.4103/jfmpc.jfmpc_34_24
  14. Kranke P, Weiniger CF, Sultan P, Achebe MO, Filipescu D, et al. Iron deficiency and anemia in pregnancy: a call to action!: -"If you don't take a temperature, you can't find a fever". Int J Obstet Anesth. 2024;62:104298. doi:10.1016/j.ijoa.2024.104298
  15. Larson LM, Baldi A, Hasan MI, Jones N, Pickle EO, et al. Role of hepcidin on benefits and risks of supplementation with iron syrup and multiple micronutrient powders in Bangladeshi children: a sub-study to a randomized controlled trial. Am J Clin Nutr. 2025. doi:10.1016/j.ajcnut.2025.02.018
  16. Fijn R, Ablij HC, Knoester PD, Witte AMC. Real-world evaluation of an intravenous iron service for the treatment of iron deficiency with or without anemia. Sci Rep. 2025;15:12093. doi:10.1038/s41598-025-85880-9
  17. Bhutta ZA, Keats EC, Owais A, González-Fernández D, Udomkesmalee E, et al. What works for anemia reduction among women of reproductive age? Synthesized findings from the exemplars in anemia project. Am J Clin Nutr. 2025;121 Suppl 1:S68. doi:10.1016/j.ajcnut.2024.11.031
  18. Owais A, Habib A, Ahsan H, Merritt CE, Lee C, et al. Drivers of anemia reduction among women of reproductive age in Pakistan: a mixed-methods country case study. Am J Clin Nutr. 2025;121 Suppl 1:S46. doi:10.1016/j.ajcnut.2024.04.037
  19. Duan Y, Xu Y, Wei Y, Liu T, Xu T, et al. Bilateral segmental testicular infarction secondary to iron deficiency anemia: a case report. BMC Urol. 2025;25:70. doi:10.1186/s12894-025-01756-0
  20. Warner MA, Johnson ML, Hanson AC, Fortune E, Flaby GW, et al. Practical Anemia Bundle and Hemoglobin Recovery in Critical Illness: A Randomized Clinical Trial. JAMA Netw Open. 2025;8:e252353. doi:10.1001/jamanetworkopen.2025.2353
  21. Hidayat MT, Khadijah Maharani SN, Ramadhany ID, Khairani NI, Rahman NA, et al. Controlled release of deferiprone using iron-responsive nanoparticles integrated with dissolving microneedle for novel alternative treatments of β-thalassemia major. Eur J Pharm Biopharm. 2025;210:114702. doi:10.1016/j.ejpb.2025.114702
  22. Al-Taiar A, Ziyab AH, Hammoud MS, Al-Sabah R, Akhtar S. Anemia in pregnant women: findings from Kuwait birth cohort study. BMC Pregnancy Childbirth. 2025;25:326. doi:10.1186/s12884-025-07439-w
  23. Sohn SH, Sul H, Kim B, Zang D. Effects of Darbepoetin Alfa and Ferric Derisomaltose Plus Darbepoetin Alfa in Functional Iron-Deficiency Anemia. Int J Mol Sci. 2025;26. doi:10.3390/ijms26052203
  24. Nagao T, Takahashi K, Takahashi S, Yokomizo R, Samura O, et al. Low-dose ferric carboxymaltose vs. oral iron for improving hemoglobin levels in postpartum East Asian women: A randomized controlled trial. PLoS One. 2025;20:e0319795. doi:10.1371/journal.pone.0319795
  25. Ozeki Y, Kato J, Ohta Y, Taida T, Horio R, et al. [Efficacy and safety of ferric carboxymaltose in patients with inflammatory bowel disease]. Nihon Shokakibyo Gakkai Zasshi. 2025;122:196. doi:10.11405/nisshoshi.122.196
  26. Gao Z, Gao Y, Wang Q, Wang Q, Lu P, et al. Study on HIF-PHI combined with iron supplement in treatment of renal anemia in rats. BMC Nephrol. 2025;26:125. doi:10.1186/s12882-025-04045-y
  27. Liu X, Sun A, Zheng X, Xia M, Liu Y, et al. Combined morphological and molecular approaches to the clinical diagnosis of Necator americanus infection: a case report. J Med Case Rep. 2025;19:100. doi:10.1186/s13256-025-05105-5
  28. Zhang H, Sun W, Qi J, Qayum A, Li J, et al. Antianemic Activity, Inhibition of Oxidative Stress, and Iron Supplementation in Mice with Iron-Deficiency Anemia through HG-Hawthorn Pectin-Iron(III) Complexes. ACS Appl Bio Mater. 2025;8:2419. doi:10.1021/acsabm.4c01905
  29. Dogan Y, Dede AM, Erdoğan A. An unusual association: gastric xanthelasma presenting with iron deficiency anemia: a case report. J Med Case Rep. 2025;19:98. doi:10.1186/s13256-025-05133-1
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