'
SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
6.3
USERS' SCORE
Very Good
Based on 207 Reviews
8.7
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
L-Theanine
200 mg
*
Inositol
100 mg
*

Top Medical Research Studies

8
Inositol reduces anxiety in hens
Dietary Inositol Reduces Fearfulness and Avoidance in Laying Hens.
Highlights study's focused results
We conducted a study to understand how inositol, a naturally occurring sugar alcohol, influences anxiety levels in laying hens. Our focus was on the behavior of Lohmann LSL lite hens, which were fed two different diets—one rich and one deficient in protein—while receiving either pure inositol or high levels of phytase.

Throughout the experimental period from 19 to 59 weeks of age, we gathered data through multiple behavior assessments, which included observing their reactions to new objects and monitoring their overall health indicators like feather condition and mortality rates.

Interestingly, inositol appeared to help reduce fearfulness in these hens, which we observed through a decrease in the time it took for them to approach and peck at new objects. However, it's worth noting that while inositol also led to a drop in vent feather cover and was associated with a slight increase in mortality, its primary benefit was tied to its ability to lessen anxiety.

Phytase, on the other hand, did not yield similar effects on behavior or health. These findings point towards the potential of inositol as a useful dietary addition for improving the well-being of laying hens by reducing anxiety levels.
Read More
8
d-Pinitol shows potential for anxiety
Neuropharmacological effects of d-pinitol and its possible mechanisms of action.
Focused on anxiolytic effects
We explored how d-pinitol, a natural compound found in various fruits and legumes, could impact anxiety and related conditions. In our evaluation, we focused on its effects on mice to understand its potential as an anxiolytic agent.

During our study, we observed that when mice were given d-pinitol at doses ranging from 1 to 100 mg/kg, there was notable evidence of anxiolytic-like actions. In particular, at a dose of 70 mg/kg, d-pinitol showed significant effectiveness in reducing anxiety as assessed in specific behavioral tests.

We also investigated the possible mechanisms behind these effects. Our findings suggest that the GABAergic system may play a key role in mediating the anxiolytic benefits of d-pinitol, which indicates a promising direction for further research. It’s important to remember that while our results are encouraging, d-pinitol did not exhibit diuretic effects, which was a secondary focus of the study.

All in all, our study positions d-pinitol as a compelling candidate for alleviating anxiety, with mechanisms worth exploring further for therapeutic applications.
Read More
7
Myo-Inositol improves anxiety behavior
Assessment of Long-Term Safety and Efficacy of Purple Sweet Potato Color (PSPC) and Myo-Inositol (MI) Treatment for Motor Related and Behavioral Phenotypes in a Mouse Model of Classic Galactosemia.
Relevant focus on anxiety treatment
We aimed to explore the impact of myo-inositol (MI) on anxiety in a mouse model of classic galactosemia. Our research involved a combination of acute and chronic evaluations of MI, particularly looking at its effects over a long-term treatment period. We observed that lower doses of MI suggested notable improvements in motor deficits and anxiety-driven hyperactivity among the GalT-KO mice, which are affected by this condition.

While we conducted a thorough assessment of motor-related behaviors and anxiety levels, it appears that MI holds potential as an adjunct treatment option. These findings indicate that MI may benefit not only physical symptoms but also emotional well-being, particularly in reducing anxiety-related behaviors in this genetically modified model, which helps us understand its role more clearly. The results could point to new avenues for managing anxiety, especially in conditions like classic galactosemia where traditional treatment methods fall short.
Read More

Most Useful Reviews

9.5
Calmness achieved
I’ve noticed very positive effects; I cope with anxiety better, feel more confident, and remain calm. It positively influences my mood and helps concentration without causing drowsiness. I take it regularly; its effect is similar to that of good tea. I highly recommend it to everyone.
Read More
8.8
Stress relief
My doctor recommended this amino acid after I had Covid. It's excellent for relieving stress and anxiety and also strengthens blood vessels. I’m currently on my second pack.
Read More
9.5
Natural relaxation
L-theanine helps me relax and unwind naturally. I’ve been using it for a few weeks and feel more relaxed with no negative side effects. It effectively reduces stress and anxiety.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
6.3
8
Inositol reduces anxiety in hens
Dietary Inositol Reduces Fearfulness and Avoidance in Laying Hens.
Highlights study's focused results
We conducted a study to understand how inositol, a naturally occurring sugar alcohol, influences anxiety levels in laying hens. Our focus was on the behavior of Lohmann LSL lite hens, which were fed two different diets—one rich and one deficient in protein—while receiving either pure inositol or high levels of phytase.

Throughout the experimental period from 19 to 59 weeks of age, we gathered data through multiple behavior assessments, which included observing their reactions to new objects and monitoring their overall health indicators like feather condition and mortality rates.

Interestingly, inositol appeared to help reduce fearfulness in these hens, which we observed through a decrease in the time it took for them to approach and peck at new objects. However, it's worth noting that while inositol also led to a drop in vent feather cover and was associated with a slight increase in mortality, its primary benefit was tied to its ability to lessen anxiety.

Phytase, on the other hand, did not yield similar effects on behavior or health. These findings point towards the potential of inositol as a useful dietary addition for improving the well-being of laying hens by reducing anxiety levels.
Read More
8
d-Pinitol shows potential for anxiety
Neuropharmacological effects of d-pinitol and its possible mechanisms of action.
Focused on anxiolytic effects
We explored how d-pinitol, a natural compound found in various fruits and legumes, could impact anxiety and related conditions. In our evaluation, we focused on its effects on mice to understand its potential as an anxiolytic agent.

During our study, we observed that when mice were given d-pinitol at doses ranging from 1 to 100 mg/kg, there was notable evidence of anxiolytic-like actions. In particular, at a dose of 70 mg/kg, d-pinitol showed significant effectiveness in reducing anxiety as assessed in specific behavioral tests.

We also investigated the possible mechanisms behind these effects. Our findings suggest that the GABAergic system may play a key role in mediating the anxiolytic benefits of d-pinitol, which indicates a promising direction for further research. It’s important to remember that while our results are encouraging, d-pinitol did not exhibit diuretic effects, which was a secondary focus of the study.

All in all, our study positions d-pinitol as a compelling candidate for alleviating anxiety, with mechanisms worth exploring further for therapeutic applications.
Read More
7
Myo-Inositol improves anxiety behavior
Assessment of Long-Term Safety and Efficacy of Purple Sweet Potato Color (PSPC) and Myo-Inositol (MI) Treatment for Motor Related and Behavioral Phenotypes in a Mouse Model of Classic Galactosemia.
Relevant focus on anxiety treatment
We aimed to explore the impact of myo-inositol (MI) on anxiety in a mouse model of classic galactosemia. Our research involved a combination of acute and chronic evaluations of MI, particularly looking at its effects over a long-term treatment period. We observed that lower doses of MI suggested notable improvements in motor deficits and anxiety-driven hyperactivity among the GalT-KO mice, which are affected by this condition.

While we conducted a thorough assessment of motor-related behaviors and anxiety levels, it appears that MI holds potential as an adjunct treatment option. These findings indicate that MI may benefit not only physical symptoms but also emotional well-being, particularly in reducing anxiety-related behaviors in this genetically modified model, which helps us understand its role more clearly. The results could point to new avenues for managing anxiety, especially in conditions like classic galactosemia where traditional treatment methods fall short.
Read More
7
Inositol as potential anxiety treatment
Pharmacological Therapy in Panic Disorder: Current Guidelines and Novel Drugs Discovery for Treatment-resistant Patient.
Relevant effectiveness of inositol
We examined the potential of inositol as a treatment for anxiety disorders. While several treatments are currently available, many patients still struggle with symptoms, leading us to seek out alternatives like inositol.

Our findings suggest that inositol may have anti-panic effects, indicating it is worth considering for those who haven’t found success with other medications. We noted that it was generally well tolerated, which is essential for anyone looking for anxiety relief without unpleasant side effects.

While inositol shows promise, further research is necessary to firmly establish its efficacy. In this case, it's important to keep expectations grounded and recognize that individual responses may vary.

Overall, inositol presents itself as a intriguing option, especially for patients facing treatment-resistant conditions, highlighting the ongoing need for fresh approaches to managing anxiety.
Read More
4
Myo-inositol shows no significant anxiety effects
Maternal mood, anxiety and mental health functioning after combined myo-inositol, probiotics, micronutrient supplementation from preconception: Findings from the NiPPeR RCT.
Supplement effects are unclear
Our study examined the effects of a combined supplement of myo-inositol, probiotics, and micronutrients on the mental wellbeing of women from preconception through pregnancy and into the post-delivery period. We designed a double-blind randomized trial to compare this specific supplement with a standard micronutrient supplement. Our goal was to see if the intervention could lead to reduced anxiety and improved mood in participants.

Throughout various stages of pregnancy and after delivery, we measured mood and anxiety levels using established scales. We found that while there were no significant differences between the supplement group and the control group in terms of anxiety and mood symptoms, there was a modest improvement in overall mental health functioning for those taking the combined supplement. Specifically, women in the intervention group experienced a slight uptick in their mental health scores by 1.21 points compared to the control group by six months post-delivery.

Ultimately, while our findings did not indicate a meaningful impact on anxiety levels, they do suggest that taking myo-inositol along with other nutrients could support overall mental health during the perinatal period, offering some benefits beyond mood and anxiety symptoms alone.
Read More

User Reviews

USERS' SCORE
Very Good
Based on 207 Reviews
8.7
10
Stress relief
L-Theanine has been a game-changer for me. It provides a noticeable sense of calm and relaxation without drowsiness. It has improved my focus and mental clarity, making it invaluable for managing stress. Highly recommended for stress relief.
9.5
Calmness achieved
I’ve noticed very positive effects; I cope with anxiety better, feel more confident, and remain calm. It positively influences my mood and helps concentration without causing drowsiness. I take it regularly; its effect is similar to that of good tea. I highly recommend it to everyone.
Read More
9.5
Natural relaxation
L-theanine helps me relax and unwind naturally. I’ve been using it for a few weeks and feel more relaxed with no negative side effects. It effectively reduces stress and anxiety.
9.5
Stress management
I regret not discovering this earlier! Theanine has become an essential part of my daily routine to manage stress. It helps me stay calm and collected, reducing anxiety without sedation.
9.5
Mental clarity
This product has saved me from anxiety and stress. After taking it, I can think clearly and respond to stress in a calm manner. My sleep has improved tremendously, and I wake up refreshed and ready to face the day.
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