NOW Supplements Magnesium

Magnesium sulfate alleviates postoperative pain

Based on 16 Researches

USERS' SCORE

Excellent

Based on 20 Reviews

Effects of magnesium sulfate on periarticular infiltration analgesia in total knee arthroplasty: a prospective, double-blind, randomized controlled trial.

Most Relevant Research

We explored the impact of magnesium sulfate on managing pain following total knee arthroplasty. In a randomized, double-blind trial with 90 patients, half received a blend of analgesics that included magnesium sulfate, while the other half did not.

Following surgery, the results showed that magnesium sulfate helped prolong pain relief and reduced the need for opioids. Patients receiving it experienced less postoperative pain and moved towards recovery more effectively.

Overall, adding magnesium sulfate appears beneficial for postoperative knee pain management.

9.5

Pain relief

Most Useful Review

It didn't run out of magnesium, and it helped alleviate my knee pain significantly. I appreciated that one capsule meets my daily needs. Excellent brand. Thank you, iHerb, for the fast delivery to Rio de Janeiro; it arrived in just 10 days.

Back Pain details

Magnesium reduces postoperative back pain

Based on 7 Researches

Effect of perioperative intravenous magnesium sulfate on postoperative pain after iliac venous stenting.

Most Relevant Research

We explored the effectiveness of magnesium sulfate (MS) in relieving low back pain (LBP) for patients who underwent iliac venous stenting. This study involved 97 patients, divided into two groups: one received MS infusion during their surgery, while the other did not.

Patients who received MS experienced significantly lower pain levels at all follow-up intervals. We found that, at 24 hours after surgery, those in the magnesium group consumed much less tramadol—a common pain medication—compared to the control group. Additionally, the need for extra pain relief was lower among those who received magnesium.

Importantly, the side effects like nausea and vomiting were similar in both groups, indicating that magnesium can be a safe option for pain management after this type of surgery. Overall, the findings suggest that magnesium sulfate not only alleviates pain but also reduces reliance on opioids, making it a valuable treatment for postoperative care.

9.5

Pain relief noted

Most Useful Review

The effect is noticeable from the very first capsule! I have a neurological disability and take magnesium regularly. This magnesium is excellent for alleviating spasticity, promoting sleep, and is perfect for irritable bowel syndrome as it quickly eases abdominal pain. I am very pleased with the purchase and will order more.

Headache details

Magnesium aids migraine management

Magnesium and Migraine.

Most Relevant Research

We explored the impact of magnesium on migraine headaches, focusing on its potential benefits based on various studies. Magnesium deficiency is quite common and can arise from different factors, such as not consuming enough through diet or losing more through bodily systems.

A wealth of research, including case reports and controlled trials, suggests that magnesium supplementation can effectively alleviate migraines, both in the short term and long term. The proposed reasons for this effectiveness range from magnesium's role in preventing spreading cortical depression to its ability to manage oxidative stress and inflammation.

This evidence leads us to consider magnesium not just as a dietary supplement but as an important player in migraine management. Understanding these links helps us contemplate magnesium’s role in prevention and treatment, promising a potential path for those who suffer from this debilitating condition.

9.5

Fewer headaches

Most Useful Review

I used to suffer from frequent headaches several times a week. After taking this supplement for two months, they have significantly decreased. I will purchase more!

Insomnia details

Magnesium improves elderly insomnia

The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial.

Most Relevant Research

We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.

Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.

The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.

Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.

8.8

Reduced insomnia symptoms

Most Useful Review

This magnesium is excellent for its price. As a doctor, I recommend it for insomnia and sweet cravings. I noticed improvements in sleep and reduced anxiety after just one dose. My sweet cravings vanished within a week. The capsules are large yet easy to swallow. Given today’s pace of life, magnesium is essential. I will definitely order more for my family.

Anxiety details

Magnesium treats anxiety in MS

Nanoparticulate MgH ameliorates anxiety/depression-like behaviors in a mouse model of multiple sclerosis by regulating microglial polarization and oxidative stress.

Most Relevant Research

We aimed to understand the impact of nanoparticulate magnesium hydride (MgH) on anxiety and depression associated with multiple sclerosis (MS). Our exploration involved studying how MgH affects mood disorders in a model we designed, specifically using experimental autoimmune encephalomyelitis (EAE) mice.

We discovered that MgH treatment significantly alleviated anxiety and depression-like behaviors in these mice. Not only did MgH help improve their mood, but it also reduced overall disease severity and inflammatory damage within the central nervous system.

Importantly, our findings suggest that MgH could be working by promoting healthier microglial activity. It appears to encourage the beneficial M2 polarization while inhibiting the harmful M1 polarization, alongside reducing oxidative stress. This mechanism offers a glimpse into how magnesium might truly enhance well-being for those dealing with MS-related psychiatric issues.

In summary, our research indicates that nanoparticulate MgH holds promise as a non-toxic and effective treatment option for anxiety and depression in people suffering from MS, showcasing a potential breakthrough in managing these debilitating conditions.

9.5

Reduced anxiety

Most Useful Review

Taking magnesium improved my overall health and significantly reduced my muscle cramps and eyelid twitches. I no longer suffer from anxiety, and my general well-being has enhanced. If you find this review helpful, please like it!

Leg Cramps details

Magnesium oxide treats leg cramps

Likely Ineffective

Based on 17 Researches

A randomized, double-blind, placebo-controlled, multicenter study assessing the efficacy of magnesium oxide monohydrate in the treatment of nocturnal leg cramps.

Most Relevant Research

We conducted a study to evaluate how effective magnesium oxide monohydrate (MOMH) is in treating nocturnal leg cramps (NLC). This was a randomized, double-blind, placebo-controlled trial involving multiple centers in Ukraine, where participants took either MOMH or a placebo nightly for 60 days.

Our focus was on measuring the frequency and duration of cramps, the pain they caused, and how they affected sleep quality and overall life satisfaction. We used thorough statistical methods to compare the results between the two groups.

The findings indicated that MOMH is both effective and safe for individuals dealing with NLC. Participants reported improvements in their symptoms, demonstrating that this magnesium supplement can play a helpful role in managing nocturnal leg cramps.

9.5

Relieves restless legs

Most Useful Review

These magnesium capsules really do the trick! I’ve endured restless legs and leg cramps for years, and since starting magnesium, I've noticed a remarkable difference. I certainly feel it if I forget to take my magnesium at night. I appreciate that they don’t contain calcium, as I’ve learned that these supplements should be taken separately.

Athlete’s Foot details

I cannot live without this magnesium, and several family members use it too. I had pain in my left foot that made stepping difficult, especially at night. After researching, I realised it was inflammation of the tissue covering the bone. I started taking Magnesium Dimalate and within a week, the pain vanished. My friend had the same issue and found relief as well. It is very helpful for muscle pain, athlete’s foot, fibromyalgia, and tendonitis.

Depression details

Magnesium intake reduces depression risk

Based on 16 Researches

Dietary Magnesium Intake in Relation to Depression in Adults: A GRADE-Assessed Systematic Review and Dose-Response Meta-analysis of Epidemiologic Studies.

Most Relevant Research

We conducted a systematic review and meta-analysis exploring how dietary magnesium (Mg) intake connects with depression among adults. By reviewing data from over 63,000 individuals, we found that those with the highest magnesium intake had a 34% lower chance of experiencing depression compared to those with the lowest intake.

Furthermore, our analysis indicated that every increase of 100 mg per day in magnesium intake was linked to a 7% reduced risk of depression. These findings suggest that increasing dietary magnesium could play a valuable role in lowering depression risk.

9.5

Reduced anxiety

Most Useful Review

Every woman should consider magnesium, as deficiency can lead to heart issues and affect mental health, causing anxiety and depression. After taking one capsule daily, my leg cramps vanished, I became calmer, and my insomnia improved significantly. I find it a bargain for six months' supply.

Hypothyroidism details

Magnesium shows promise in thyroid recovery

Based on 3 Researches

Proof of concept of the WOMED model of benign thyroid disease: Restitution of thyroid morphology after correction of physical and psychological stressors and magnesium supplementation.

Most Relevant Research

We set out to investigate how magnesium, along with selenium and coenzyme Q10, could influence hypothyroidism in patients with benign thyroid diseases. Our approach included a small group of eight patients—five with hyperthyroidism and three with hypothyroidism—who received additional treatment aimed at addressing both their thyroid condition and related physical and psychological stresses.

Over a period of 2 to 4 years, we observed some significant changes. Initially, we focused on correcting musculoskeletal issues, followed by addressing stress. As a result, we noted that thyroid morphology normalized in many cases, which was confirmed through ultrasound examinations. Interestingly, we also saw a reduction in thyroid antibody levels for most patients.

However, we must be transparent about our findings. While magnesium and the other supplements showed promise, there were two cases of chronic thyroiditis that did not respond positively to treatment, possibly due to long-standing fibrosis. This indicates that while magnesium may play a role in thyroid health, its effectiveness can vary significantly based on individual circumstances and the duration of the thyroid condition.

9.5

Improved thyroid function

Most Useful Review

I suffer from hypothyroidism and know magnesium is vital for thyroid function, converting inactive T4 to active T3. I take one capsule of magnesium glycinate nightly and have noticed my leg cramps are gone. It's important to ensure adequate intake, particularly for those with hypothyroidism, and I'm grateful for its benefits when combined with other vitamins.

Cardiovascular Disease details

Magnesium's impact on heart health

The Role of Dietary Magnesium in Cardiovascular Disease.

Most Relevant Research

We examined the connection between dietary magnesium and cardiovascular disease, focusing on how magnesium intake or serum levels relate to heart health. Over the last couple of decades, numerous studies have shown that low magnesium levels are associated with several heart-related issues, including high blood pressure, heart attacks, and even heart failure.

Our insights reveal that even mild or moderate magnesium deficiencies can trigger physiological and metabolic changes that may heighten cardiovascular risks. When magnesium levels are insufficient, we see a rise in inflammation, oxidative stress, and issues with how fats are processed in the body, which can lead to serious heart problems.

Furthermore, we noted that many individuals often consume less magnesium than what is recommended, particularly those who do not regularly eat whole grains, legumes, or green vegetables. This widespread lack of magnesium is concerning, as it could be a significant factor influencing heart disease in the general population.

9.5

Effective for insomnia

Most Useful Review

Recommended for maintaining good health! I've heard that a lack of magnesium can increase the risk of insomnia and cardiovascular disease. Since I started taking it an hour before bed, I now fall asleep more quickly. It's been three weeks, and it helps my insomnia significantly. The supplement is large, so be cautious if you struggle to swallow. Magnesium is vital for health support, and I intend to continue taking it.

Irritable Bowel Syndrome details

Magnesium boosts colonic activity

Effects of oral magnesium sulphate on colonic motility in patients with the irritable bowel syndrome.

Most Relevant Research

We set out to understand how magnesium sulphate influences the symptoms of irritable bowel syndrome (IBS). In a study involving 20 IBS patients, magnesium sulphate was administered orally, resulting in a quick boost in colonic motor activity. Most participants experienced this increase within just two to six minutes.

Specifically, the percentage of colonic activity rose from 16.2% to 23.7%, signaling a notable change. Those who often felt abdominal pain after eating showed even more pronounced reactions, with their activity jumping from 16.1% to 29.8%. However, it’s important to note that three of these patients still experienced their usual pain after taking magnesium, suggesting that while magnesium can enhance motility, it doesn’t eliminate the pain for everyone.

Ultimately, these findings lend support to the idea that some cases of abdominal pain related to food may stem from heightened intestinal responses to cholecystokinin, a hormone released by the intestine. So while magnesium shows promise for intriguing changes in colonic movement in IBS patients, its effectiveness in alleviating pain remains mixed.

9.5

Effective soothing relief

Most Useful Review

The effect is noticeable from the very first capsule! I have a neurological disability and regularly take magnesium supplements. This magnesium is very good; it quickly relaxes my spasticity and helps me sleep better if taken in the evening. It also soothes my irritable bowel syndrome, with abdominal pains easing quickly. I'm very pleased with my purchase and shared it with my mum. I'll definitely order more.

Kidney Stones details

Magnesium reduces kidney stone risk

Based on 9 Researches

Effect of magnesium oxide or citrate supplements on metabolic risk factors in kidney stone formers with idiopathic hyperoxaluria: a randomized clinical trial.

Most Relevant Research

We conducted a randomized, double-blind, placebo-controlled clinical trial to explore how magnesium treatments influence kidney stones, specifically for those with high levels of oxalate in their urine. Our study involved 90 participants with a history of calcium kidney stones, all of whom were experiencing idiopathic hyperoxaluria. They were divided into three groups receiving either magnesium oxide (MgO), magnesium citrate (MgCit), or a placebo for eight weeks, while their diets were monitored to keep nutritional intake consistent.

After the treatment period, we observed promising results. Both MgO and MgCit effectively reduced the excretion of oxalate in urine, which is a key factor in kidney stone formation. The Group taking magnesium citrate showed even more significant reductions in both oxalate levels and the calcium oxalate supersaturation index, which measures the concentration of stone-forming minerals in urine. This was notably true for participants with normal magnesium levels.

Overall, we found that magnesium supplements might play a beneficial role in decreasing critical risk factors for kidney stones, especially for those using magnesium citrate. It's encouraging to see that this may offer a practical option for those struggling with recurrent stones due to high oxalate excretion.

9.5

Kidney health improvement

Most Useful Review

I spent a long time searching for the right magnesium for my kidney health and found it with this product. I've tried various types over the years, and after learning of my weak kidney, I discovered magnesium oxide online. This supplement from NOW contains 400 mg of magnesium oxide, citrate, and aspartate, and I'm now very satisfied.

Vertigo details

Effective magnesium treatment for vertigo

Likely Very Effective

Based on 3 Researches

Successful treatment of a child with definite Meniere's disease with the migraine regimen.

Most Relevant Research

We explored the relationship between magnesium treatment and vertigo in a remarkable case involving a 5-year-old girl with Meniere's disease (MD). This young patient had been suffering from six months of left-sided hearing loss, followed by troubling daily episodes of vertigo, persistent headaches, and vomiting. She met the established criteria for definite MD, which made her situation particularly concerning for both her and her family.

After initiating a 6-week diet and lifestyle regimen aimed at migraine management, which included magnesium, we observed promising results. The patient reported being symptom-free and showed a significant improvement in her hearing, reaching near-normal levels. This outcome has led us to believe that the vertigo and other symptoms associated with MD may actually be linked to a vestibular migraine phenomenon, suggesting that magnesium and lifestyle changes could play a key role in alleviating these symptoms in pediatric patients.

Our findings suggest that children with MD might benefit from these migraine-oriented lifestyle modifications, highlighting the need for some researchers and caregivers to consider alternative approaches for treating children's vestibular symptoms.

9.5

Reduced eye twitches

Most Useful Review

Magnificent magnesium at a great price! I take it alongside vitamin B6 (100 mg) for a month, then have a break. Remarkably, I noticed my eye twitching ceased by the fifth day! I had suffered for 2-3 months before starting this. The price is much lower than at local pharmacies, and it’s sufficient for the whole family. A vital supplement for the body.

Autoimmune Disorder details

Magnesium shows promise for RA treatment

Based on 10 Researches

Magnesium Supplementation Modifies Arthritis Synovial and Splenic Transcriptomic Signatures Including Ferroptosis and Cell Senescence Biological Pathways.

Most Relevant Research

We analyzed how magnesium supplementation affects the biology of rheumatoid arthritis (RA) in mice. By feeding one group a diet rich in magnesium and another a standard diet over 15 days, we examined changes in their tissue responses.

Our findings revealed that increased magnesium intake may alter gene expression linked to oxidative stress and cellular aging, processes that are significant in RA development. This suggests that magnesium could be beneficial for managing RA and potentially other autoimmune disorders by reducing disease severity and joint damage.

9.5

Quick relaxation

Most Useful Review

The effects were noticeable within my first capsule! With a neurological disability, I regularly take magnesium. This particular one works effectively; my spasticity relaxes quickly and aids my sleep, so it’s best taken in the evening. It alleviates my irritable bowel syndrome, and I’m very pleased with my purchase.

Chronic Fatigue Syndrome details

Magnesium potentially benefits CFS patients

Based on 5 Researches

Red blood cell magnesium and chronic fatigue syndrome.

Most Relevant Research

We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.

In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.

In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.

8.3

Reduced muscle tension

Most Useful Review

This supplement effectively alleviates various symptoms of chronic fatigue syndrome, including nervous and muscle tension, cravings, poor sleep, and headaches. I noticed improvements after two years of regular use, transforming me from a tired individual to a more balanced person.

Diabetes details

Magnesium intake benefits diabetes patients

Based on 19 Researches

Associations of dietary magnesium intake with the risk of atherosclerotic cardiovascular disease and mortality in individuals with and without type 2 diabetes: A prospective study in the UK Biobank.

Most Relevant Research

We investigated the link between dietary magnesium intake and the risk of heart disease and death in over 149,000 individuals, including those with type 2 diabetes. Through careful analysis over a median of 12 years, we found that higher magnesium intake was associated with significantly lower risks of heart disease and mortality in individuals with diabetes.

However, this benefit wasn't seen in those without diabetes. Our findings highlight the potential for magnesium to play a crucial role in health management for people living with type 2 diabetes, signaling the need for tailored dietary guidance.

9.5

Diabetes balance

Most Useful Review

I found great benefits in balancing my diabetes.

High Cholesterol details

Magnesium chloride reduces liver stress

Based on 9 Researches

Protective Effects of Magnesium Chloride on Liver Enzymes and Biomarkers of Oxidative Stress in high fat diet fed Rats.

Most Relevant Research

We aimed to find out how magnesium chloride influences liver health and oxidative stress in rats on a high-fat diet.

In our study, groups of rats were fed either a normal diet, a high-fat diet, or a high-fat diet supplemented with magnesium chloride.

We found that those receiving magnesium showed lower levels of liver enzymes and oxidative stress markers compared to the high-fat diet group alone.

This suggests that magnesium chloride could help protect against the harmful effects of a high-fat diet, although its efficacy in humans needs further investigation.

8.8

Lowers blood pressure

Most Useful Review

Reduces high blood pressure, relaxing my heart and muscles.

Migraine details

Magnesium reduces migraine symptoms

Based on 17 Researches

Magnesium and Migraine.

Most Relevant Research

We explored how magnesium supplementation can help alleviate migraines, a condition that affects countless individuals and can be incredibly disabling. Research has shown a strong link between magnesium deficiency and various factors that contribute to migraines, such as neurological changes and inflammation.

Studies, including randomized controlled trials, indicate that magnesium can reduce the frequency and severity of migraine attacks, both in the short term and as a preventative measure. This effectiveness is thought to stem from magnesium's ability to influence nerve function and reduce stress responses in the body.

We've examined the accumulating evidence from case studies and clinical trials, and it clearly points to magnesium being a valuable option for those suffering from migraines. By addressing magnesium deficiency, we may offer a new avenue for relief and improved management of this challenging condition.

9.5

Improved migraines

Most Useful Review

One of my favourite brands, with one minor downside: it may cause looseness of the stool due to citrate. I take magnesium for muscle cramps and headaches, using 10 mg per kg of body weight. I weigh roughly 50 kg, so the dosage works perfectly. Since using this supplement, I’ve had to take fewer capsules than various other brands. Overall, it's effective, especially for ensuring I maintain adequate magnesium levels for my health.

Osteoporosis details

Magnesium's role in osteoporosis therapy

Based on 19 Researches

Mg-ZIF nanozyme regulates the switch between osteogenic and lipogenic differentiation in BMSCs via lipid metabolism.

Most Relevant Research

We explored the effects of a special material called magnesium-based zeolitic imidazolate frameworks, or Mg-ZIF, on osteoporosis. This study aimed to find a way to tackle osteoporosis by reducing reactive oxygen species (ROS)—harmful molecules that affect our bone health.

Our findings revealed that Mg-ZIF is effective at scavenging ROS, which helps boost the bone-forming ability of bone mesenchymal stem cells (BMSCs). By promoting osteogenic differentiation, Mg-ZIF supports the formation of new bone while simultaneously discouraging the development of fat cells from BMSCs, a process known as lipogenic differentiation.

In our in vivo experiments, we confirmed that administering Mg-ZIF could successfully lower ROS levels and mitigate the effects of osteoporosis. On a deeper level, the mechanism behind this involves Mg-ZIF enhancing BMSC differentiation into bone-forming cells by upregulating specific lipid metabolic pathways.

Overall, we believe that Mg-ZIF holds promise as a therapeutic approach for osteoporosis. By addressing the oxidative stress in the bone marrow environment, it opens a new door for potential treatments targeting this common bone disease.

9.5

Helps with osteoporosis

Most Useful Review

Magnesium helps alleviate insomnia, muscle cramps, and anxiety, and it’s essential for calcium absorption, which aids in preventing osteoporosis. I take a pill before bed and found my body adjusted well to it after initial relaxation effects.

Constipation details

Effective treatment for chronic constipation

Based on 22 Researches

Senna Versus Magnesium Oxide for the Treatment of Chronic Constipation: A Randomized, Placebo-Controlled Trial.

Most Relevant Research

We explored the effectiveness of magnesium oxide (MgO) as a treatment for chronic constipation using a robust randomized, placebo-controlled trial. Over 28 days, participants received MgO, senna, or a placebo.

Both MgO and senna significantly improved bowel movement frequency and quality of life compared to placebo. About 68.3% of those using MgO reported symptom improvement, showcasing its potential as an effective osmotic agent alongside a stimulant laxative.

Importantly, there were no severe treatment-related side effects reported during the trial.

8.8

Effective for constipation

Most Useful Review

I’ve been taking magnesium for a long time and am always pleased with the results. It calms and acts as a mild laxative, making it great for those suffering from constipation. My family and I all take one capsule a day and it keeps us happy!

Blood Clot details

My digestion was slow with significant constipation due to age and medication. After taking magnesium for 8 months, I experienced no constipation and improved digestion. An added benefit was that a blood test showed my cholesterol had increased good levels and decreased bad levels, bringing me within acceptable limits.

Heart Attack details

Magnesium implantation improves heart recovery

Based on 23 Researches

Magnesium implantation as a continuous hydrogen production generator for the treatment of myocardial infarction in rats.

Most Relevant Research

We explored the potential of magnesium implantation as a new approach to combat heart attacks, specifically myocardial infarction (MI). Our research centered on using magnesium slices implanted under the skin of rats to generate hydrogen gas continuously. This method could ensure a greater and longer-lasting concentration of hydrogen directly reaching the heart, which is crucial for its therapeutic effects.

Through our study, we measured how effectively the magnesium produced hydrogen and evaluated its safety. The results were promising; we observed that magnesium implantation not only improved cardiac function in rats suffering from MI, but also played a role in eliminating harmful free radicals from mitochondrial dysfunction. Furthermore, it helped reduce cell death in heart muscle cells, which is a common consequence of heart attacks.

Compared to traditional hydrogen inhalation, which has limitations in delivering sufficient doses over time, magnesium implantation proved to be a superior method. Overall, our findings pave the way for innovative treatments that could enhance recovery after heart attacks by harnessing the unique properties of magnesium for hydrogen production.

Normalised heart rhythm

Most Useful Review

This magnesium is easy to take and the dosage is good. I've observed positive effects, such as reduced seizures in an elderly person and calmer demeanour. It assists in normalising heart rhythm, but I recommend other sedative options for a better effect.

Heart Disease details

Magnesium supplements lower heart failure risk

Based on 16 Researches

Nonprescription Magnesium Supplement Use and Risk of Heart Failure in Patients With Diabetes: A Target Trial Emulation.

Most Relevant Research

We examined how magnesium supplements might influence heart failure and serious heart-related issues in diabetic patients.

In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.

Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.

8.8

Stabilised heart

Most Useful Review

I consider these capsules essential for managing my atrial fibrillation because I need magnesium. Having taken this complex for two years, I've noticed my heart works more steadily and no longer goes out of rhythm with the slightest excitement. The capsules are small and easy to take, although my wife prefers to empty the powder into her food. The packaging confirms this is acceptable. I highly recommend this product!

Heartburn details

Magnesium alginate offers heartburn relief

Based on 6 Researches

Emerging from gastroesophageal reflux (EMERGE): An Italian survey - II the viewpoint of the patient.

Most Relevant Research

We explored the impact of a new treatment, Marial®, on patients suffering from gastroesophageal reflux disease (GERD). In a large survey involving 56 gastroenterological offices across Italy, patients were treated with either proton pump inhibitors (PPIs), a combination of PPIs and an additional remedy, or the Marial® formulation containing magnesium alginate. The results showed that both Marial® and the combination therapy significantly reduced heartburn symptoms, with Marial® proving to be more effective than the combination. Overall, patients reported a marked improvement in their GERD-related symptoms.

9.5

No heartburn experienced

Most Useful Review

I find this magnesium is fantastic as I experience no heartburn and feel relaxed shortly after taking it at night. It also helps with my menopausal palpitations. Thank you for offering such great value for money!

Common Cold details

Restless legs improvement

Most Useful Review

I purchased this magnesium for my mother, who suffers from restless legs syndrome, particularly at night. After just three doses, she began to sleep peacefully, which is fantastic! It highlights the importance of maintaining proper magnesium levels in the body.

Sleep Apnea details

Magnesium's role in sleep apnea

Association between magnesium deficiency score and sleep quality in adults: A population-based cross-sectional study.

Most Relevant Research

We aimed to uncover the relationship between magnesium levels and sleep quality, particularly focusing on sleep apnea. Our study analyzed data from a large group of adults aged 20 and older, using a well-structured method to assess magnesium levels and the prevalence of sleep issues.

We found a notable connection between lower magnesium levels, measured as the magnesium depletion score (MDS), and the likelihood of experiencing sleep apnea. Specifically, individuals with higher MDS levels were significantly more likely to report sleep apnea, showing over three times the odds compared to those with adequate magnesium levels.

Interestingly, our research did not link magnesium deficiency to other sleep problems like insomnia or restless legs syndrome, suggesting a more complex relationship with sleep apnea alone. Additionally, we noticed that older adults with depressive symptoms showed a tendency toward excessive sleep rather than insufficient sleep.

While our findings highlight the association between magnesium deficiency and sleep apnea, they also point towards the potential of adequate magnesium intake in reducing this risk. This emphasizes the importance of maintaining proper magnesium levels for better sleep quality, especially in those at higher risk for sleep apnea.

7.5

Reduced tension

Most Useful Review

This magnesium offers excellent value for money. I take one capsule at night, and it significantly improves my sleep while reducing nervous tension. The capsules are large but easy to swallow.

Liver Disease details

I regularly purchase magnesium supplements, as many people are deficient, especially those under stress or with demanding lifestyles. After struggling with chronic migraines and using harsh medications that burdened my liver, I took 400 mg of magnesium with Vit D before bed. My migraines vanished, and my blood pressure normalised. A follow-up blood test revealed my magnesium levels were at the lower limit of normal. I highly recommend this product.

Chest Pain details

Magnesium improves chest pain outcomes

Based on 19 Researches

Effects of oral magnesium therapy on exercise tolerance, exercise-induced chest pain, and quality of life in patients with coronary artery disease.

Most Relevant Research

We examined how oral magnesium might enhance quality of life and reduce exercise-induced chest pain for those with coronary artery disease (CAD). In an impressive multicenter trial, 187 patients were randomly assigned to receive either magnesium supplements or a placebo for six months.

Our findings show that magnesium therapy improved exercise duration and decreased chest pain during exertion. Participants receiving magnesium reported both enhanced exercise tolerance and better quality of life compared to those on a placebo. This suggests that magnesium supplementation could play an important role in managing CAD symptoms.

9.5

Miracle supplement

Most Useful Review

Magnesium supplementation is essential! It supports the nervous, cardiovascular, and cartilage systems. For those with joint pain, it's a miracle supplement. My aunt suffers from osteoarthritis, but since she began taking Magnesium daily, her pain has disappeared. I highly recommend it!

Pelvic Pain details