I have had peripheral Neuropathy in both of my feet for more than 10 years. I have been to every kind of specialist in an effort to find the cause, but no one had any idea what was causing it. I had previously been taking a supplement that had 250 mg each of potassium and magnesium once daily. I began taking the NOW 400mg magnesium on 1/12/2021 and almost instantly my Neuropathy began improving. I can feel an apparent decrease in inflammation and an increase in the blood flow to my extremities. My calves and my feet definitely feel much better when sitting, standing and walking. My feet are still uncomfortable - read that: numb - when I lie down at night to sleep, but not as bad depending on what I eat. This problem didn't happen overnight, so I don't expect to be "cured" or 100% better overnight, either. But it is a start and is very encouraging. I think I'm onto something here and will be reporting this to my neurologist and endocrinologist. I've read there are some things that deplete magnesium in the body, like a high percentage or ratio of calcium in the body and frequent urination. I believe that this is a positive development and something to explore further with my doctors to look for relief. All I know is that, after all of these years, I didn't find any relief till I began taking the NOW supplement. I don't know if it was their product, the amount of dosage, type(s) of magnesium or what. But it's working for me and I'm going to keep taking it