Magnesium (elemental) (from Magnesium Oxide, Magnesium Citrate and Magnesium Aspartate)
400 mg
95%
Top Medical Research Studies
8
Magnesium treats anxiety in MS
Nanoparticulate MgH ameliorates anxiety/depression-like behaviors in a mouse model of multiple sclerosis by regulating microglial polarization and oxidative stress.
We aimed to understand the impact of nanoparticulate magnesium hydride (MgH) on anxiety and depression associated with multiple sclerosis (MS). Our exploration involved studying how MgH affects mood disorders in a model we designed, specifically using experimental autoimmune encephalomyelitis (EAE) mice.
We discovered that MgH treatment significantly alleviated anxiety and depression-like behaviors in these mice. Not only did MgH help improve their mood, but it also reduced overall disease severity and inflammatory damage within the central nervous system.
Importantly, our findings suggest that MgH could be working by promoting healthier microglial activity. It appears to encourage the beneficial M2 polarization while inhibiting the harmful M1 polarization, alongside reducing oxidative stress. This mechanism offers a glimpse into how magnesium might truly enhance well-being for those dealing with MS-related psychiatric issues.
In summary, our research indicates that nanoparticulate MgH holds promise as a non-toxic and effective treatment option for anxiety and depression in people suffering from MS, showcasing a potential breakthrough in managing these debilitating conditions.
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7
Magnesium affects anxiety via gut bacteria
Magnesium Oxide Reduces Anxiety-like Behavior in Mice by Inhibiting Sulfate-Reducing Bacteria.
We examined the link between magnesium oxide and anxiety-like behavior in mice. The research focused on how a specific type of bacteria in the gut, known as sulfate-reducing bacteria (SRB), might contribute to anxiety. When we introduced these bacteria into the mice, they exhibited increased signs of anxiety, which we measured using a test called the open field test.
Next, we explored the effect of magnesium oxide on the growth of these bacteria in both lab settings and in real-life scenarios involving psychological stress, specifically using a water avoidance stress model. Remarkably, we found that magnesium oxide effectively inhibited the growth of SRB and the production of a byproduct called hydrogen sulfide in a dose-dependent manner.
Mice subjected to stress developed an overgrowth of SRB and displayed amplified anxiety-like behavior. However, those fed a magnesium oxide-enriched diet showed reduced levels of both SRB and anxiety. Our findings suggest that magnesium may play a significant role in mitigating anxiety by altering gut bacteria dynamics.
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5
Magnesium's effects on anxiety examined
The effect of magnesium sulfate on memory and anxiety-like behavior in a rat model: an investigation of its neuronal molecular mechanisms.
We investigated how magnesium sulfate affects anxiety-like behaviors and memory in male rats suffering from induced anxiety through exposure to predator odor. By using a series of behavioral tests alongside a comparison to diazepam—an established anxiolytic medication—we aimed to assess the potential benefits of magnesium treatment in managing anxiety.
Our findings revealed that magnesium did provide some anxiolytic effects, but it fell short compared to diazepam, especially regarding its impact on anxiety. Interestingly, we noticed that the response to magnesium varied depending on the dosage used. In addition to these behavioral observations, we also examined changes in oxidative stress and nitric oxide levels in the brain, suggesting that magnesium treatment has the potential to counteract increased oxidative stress that comes with anxiety.
This research adds to the understanding of magnesium's role in anxiety management, highlighting its ability to modulate oxidative stress, although further studies will be required to fully grasp its effects and optimize its application in anxiety disorders.
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Most Useful Reviews
9
Reduced anxiety
194 people found this helpful
Taking magnesium improved my overall health and significantly reduced my muscle cramps and eyelid twitches. I no longer suffer from anxiety, and my general well-being has enhanced. If you find this review helpful, please like it!
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9
Calmer mindset
16 people found this helpful
Magnesium is essential for women; its deficiency can lead to heart and nervous system issues. After taking one capsule daily, my leg cramps and insomnia improved, and I felt calmer and more balanced.
Read More
9
Anxiety relief
15 people found this helpful
A game changer! I will never be without magnesium supplements again. After several months of taking it for PMS and sugar cravings, I investigated other benefits. My husband, who is a Type 1 Diabetic, suffers from restless legs, cramping, and severe anxiety. He reluctantly tried this brand, and now, after taking one pill at bedtime, he sleeps soundly. His moodiness from lack of sleep has vanished, and his irritability has significantly reduced. I can’t emphasise enough the benefits of magnesium.
We examined how magnesium, in combination with ibogaine, affects anxiety in veterans with traumatic brain injuries. This was part of a larger study focusing on the wellbeing of Special Operations Forces veterans, who often suffer from mental health issues like anxiety and PTSD after experiencing head trauma.
The study involved 30 male veterans, primarily with mild brain injuries. Researchers used various assessments, including scales for anxiety, to measure changes before treatment and then again one month afterward. The findings were promising, showing considerable improvements in anxiety levels, as well as in depression and PTSD symptoms.
However, it’s important to note that since magnesium was administered alongside ibogaine, we can’t isolate the effects of magnesium alone on anxiety. Although the results were encouraging, we need more controlled clinical trials to fully understand the safety and effectiveness of magnesium treatment on its own.
Overall, while magnesium may play a role in improving anxiety, further research is essential to clarify its specific impact without the influence of other treatments.
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8
Magnesium's role in anxiety treatment
Efficacy of Magnesium Sulfate and Labetalol in the Treatment of Pregnancy-Induced Hypertension and Its Effect on Anxiety and Depression: A Retrospective Cohort Study.
We explored the effects of magnesium sulfate and labetalol on managing pregnancy-induced hypertension (PIH) and their potential influence on anxiety and depression among patients. In our study, we examined data from patients diagnosed with PIH from July 2020 to July 2023 at two hospitals in Chengdu, China.
Among the 219 participants, we found that 36.1% experienced anxiety and depression. We divided patients into two groups based on treatment: one group received magnesium sulfate and labetalol, while the other group received standard treatment. It was notable that those in the magnesium sulfate and labetalol group reported significant improvements in anxiety and depression levels, as measured by the Edinburgh Postnatal Depression Scale and the Generalized Anxiety Disorder 7 scale.
However, when evaluating blood pressure control, the effectiveness was similar across both groups, which means the treatment did not significantly impact blood pressure outcomes. Overall, this research points to the possibility that magnesium sulfate and labetalol can not only help manage high blood pressure in pregnant women but may also indirectly alleviate feelings of anxiety and depression.
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8
Magnesium aids post-surgery anxiety
Effects of intravenous single-bolus lidocaine infusion versus intravenous single-bolus magnesium sulfate infusion on postoperative pain, emotional status, and quality of life in patients undergoing spine fusion surgery: a randomized study.
This study set out to understand how magnesium, combined with lidocaine, influences anxiety levels and postoperative pain in patients undergoing spine fusion surgery. We engaged 120 patients aged 18 to 60 and divided them into different groups, each receiving varying treatments, including a control group that received saline.
Importantly, we observed that the group receiving the combination of lidocaine and magnesium experienced lower anxiety and depression levels following surgery. Not only did this treatment seem to help in managing pain more effectively, but it also enhanced overall patient satisfaction three months after a single infusion.
While the study highlighted the synergistic effects of combining both medications, the specific impact of magnesium alone on anxiety isn't entirely clear. The results suggested that while magnesium played a role within the combination treatment, isolating its effect on anxiety wasn't feasible in this context.
Nonetheless, the findings are promising for those seeking alternatives to standard pain management that could include anxiety relief in the postoperative period. It opens up avenues for further research on magnesium’s individual role in emotional health.
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8
Magnesium reduces anxiety symptoms
Neuroprotective effects of magnesium against stress induced by hydrogen peroxide in Wistar rat.
We investigated how magnesium might influence anxiety, particularly when triggered by oxidative stress from hydrogen peroxide. The study involved eighteen Wistar rats divided into three groups: a control group, a group treated with hydrogen peroxide, and a group receiving both hydrogen peroxide and magnesium sulphate.
Our findings revealed that the rats exposed to hydrogen peroxide exhibited increased anxiety and signs of oxidative damage in the brain. However, those that received magnesium showed significant improvements. They not only had reduced levels of anxiety but also demonstrated less oxidative stress.
This suggests that magnesium could play a beneficial role in counteracting anxiety and the negative effects of oxidative stress. Though the results are promising, it's important to remember that further research is needed to fully understand magnesium's potential effects on anxiety in humans.
Read More
8
Magnesium treats anxiety in MS
Nanoparticulate MgH ameliorates anxiety/depression-like behaviors in a mouse model of multiple sclerosis by regulating microglial polarization and oxidative stress.
We aimed to understand the impact of nanoparticulate magnesium hydride (MgH) on anxiety and depression associated with multiple sclerosis (MS). Our exploration involved studying how MgH affects mood disorders in a model we designed, specifically using experimental autoimmune encephalomyelitis (EAE) mice.
We discovered that MgH treatment significantly alleviated anxiety and depression-like behaviors in these mice. Not only did MgH help improve their mood, but it also reduced overall disease severity and inflammatory damage within the central nervous system.
Importantly, our findings suggest that MgH could be working by promoting healthier microglial activity. It appears to encourage the beneficial M2 polarization while inhibiting the harmful M1 polarization, alongside reducing oxidative stress. This mechanism offers a glimpse into how magnesium might truly enhance well-being for those dealing with MS-related psychiatric issues.
In summary, our research indicates that nanoparticulate MgH holds promise as a non-toxic and effective treatment option for anxiety and depression in people suffering from MS, showcasing a potential breakthrough in managing these debilitating conditions.
Taking magnesium improved my overall health and significantly reduced my muscle cramps and eyelid twitches. I no longer suffer from anxiety, and my general well-being has enhanced. If you find this review helpful, please like it!
Read More
9
Calmer mindset
16 people found this helpful
Magnesium is essential for women; its deficiency can lead to heart and nervous system issues. After taking one capsule daily, my leg cramps and insomnia improved, and I felt calmer and more balanced.
Read More
9
Anxiety relief
15 people found this helpful
A game changer! I will never be without magnesium supplements again. After several months of taking it for PMS and sugar cravings, I investigated other benefits. My husband, who is a Type 1 Diabetic, suffers from restless legs, cramping, and severe anxiety. He reluctantly tried this brand, and now, after taking one pill at bedtime, he sleeps soundly. His moodiness from lack of sleep has vanished, and his irritability has significantly reduced. I can’t emphasise enough the benefits of magnesium.
Read More
7.5
Quality of sleep
15 people found this helpful
I wish I had tried these much earlier. I've only been taking them for a week to help with anxiety and depression, but already my sleep quality has improved. I haven't altered anything else in my life other than adding this supplement, and I'm eager to experience the full benefits.
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9
Improved calmness
11 people found this helpful
This excellent supplement relieves muscle tension and anxiety, improving my quality of life over two years. Regular magnesium intake transformed me from a tired person into a calm one. My emotional sensitivity and constant headaches have significantly diminished.
Anxiety is a natural and often healthy emotion characterized by feelings of worry, nervousness, or fear about an impending event or situation. While some level of anxiety is a normal reaction to stress, excessive or chronic anxiety can become a mental health issue. It may present in various forms, from everyday worries to more severe conditions such as generalized anxiety disorder (GAD), panic disorder, or social anxiety disorder. Symptoms can manifest both psychologically, such as persistent worry and difficulty concentrating, and physically, including symptoms like increased heart rate, sweating, or fatigue.
Understanding the difference between normal anxiety and an anxiety disorder is crucial. Normal anxiety can be beneficial, motivating you to prepare for important events like exams or public speaking. However, when it starts to interfere with daily activities or leads to avoidance behaviors, it may indicate the need for professional help. Treatments for anxiety often include therapy, medications, and lifestyle changes, allowing individuals to manage their symptoms effectively. If someone is struggling with anxiety that impacts their quality of life, seeking guidance from a healthcare professional is a key step toward recovery.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
Magnesium has been studied for its potential role in alleviating symptoms of anxiety, and some evidence suggests it may be beneficial. Magnesium plays a critical role in brain function and the regulation of neurotransmitters, which are essential for mood stability. Some studies have indicated that low levels of magnesium may be linked to increased anxiety symptoms, and supplementation could work to help improve overall mental health by restoring adequate magnesium levels. While it's not a standalone treatment for anxiety disorders, integrating magnesium into a balanced diet with other treatment modalities could provide additional support.
That said, it's important to approach magnesium supplementation thoughtfully. Overuse can lead to adverse effects, and individual needs may vary widely depending on dietary intake and overall health status. Before starting any new supplement, especially for managing anxiety, consulting with a healthcare professional is advisable to tailor an approach that aligns with your personal health needs. In summary, while magnesium can play a role in supporting anxiety management, it should complement traditional treatments rather than serve as a primary solution.
Based on user reviews, the timeline for noticing anxiety relief after starting magnesium supplementation can vary. Several users reported experiencing positive effects within just a few days. For instance, one reviewer noted a significant decrease in anxiety after just five days of usage Read Review. Another user mentioned that they felt calmer and more balanced within just a week of starting the supplement Read Review.
However, some users have indicated that the benefits may also take longer to fully manifest. For instance, one review highlighted that it took around ten days to notice significant improvements Read Review. Additionally, another user who has been taking magnesium for over two years remarked on consistent anxiety relief as a long-term benefit Read Review. Overall, while many users report quick results, individual responses can vary, making it essential to monitor your personal experience with the supplement.
Magnesium supplementation has garnered attention in scientific circles for its potential role in alleviating anxiety symptoms. Various studies highlight its effects, such as a systematic review that indicated magnesium may benefit individuals dealing with mild anxiety, especially those who are magnesium deficient ([3]). Another study revealed that magnesium, when paired with probiotics and other supplements, led to short-term reductions in anxiety levels among participants diagnosed with major depressive disorder ([1]). However, while the initial results are promising, they often lacked long-term effectiveness, suggesting magnesium's impact may diminish over time.
Additionally, findings from animal studies bolster the view that magnesium can mitigate anxiety-like behaviors. For instance, research showed that magnesium oxide reduced stress-induced anxiety in mice by affecting gut bacteria, and other studies identified beneficial effects in rats exposed to oxidative stress ([2], [10]). Overall, while magnesium demonstrates potential in managing anxiety, particularly in controlled settings or among specific populations, further research—including larger, more rigorous trials—is necessary to fully establish its efficacy and optimal use in anxiety treatment.
Users have shared that magnesium supplementation can lead to a variety of symptom improvements, particularly relating to anxiety and sleep. Many reviewers noted a dramatic reduction in anxiety levels, with reports ranging from quick relief within just a few days Read Review to more gradual improvements over weeks Read Review. Some users mentioned that their overall emotional well-being has seen a notable enhancement, stating they feel calmer and more balanced in their day-to-day lives Read Review.
In addition to alleviating anxiety, individuals also reported improvements in sleep quality, indicating that magnesium has helped with issues such as insomnia and restless sleep Read Review. Other supplemented experiences included reductions in muscle cramps and general well-being improvements, with some users feeling transformed from chronic tension to a more relaxed state Read Review. While the overall feedback is largely positive, it is essential to recognize that individual results can vary widely.
Users reported positive experiences when combining magnesium with other supplements for managing anxiety, particularly with vitamin B6. One reviewer noted that combining magnesium with vitamin B6 enhanced the calming effects on their mood Read Review. This combination appears to contribute to a more pronounced reduction in anxiety, reflecting how individual supplements can complement one another in boosting emotional well-being.
Overall, magnesium alone has already provided substantial relief for many users, helping to alleviate symptoms of anxiety and improve sleep quality Read Review. Several users experienced significant benefits from regular magnesium intake, leading to a calmer state and better overall health Read Review. As a result, mixing magnesium with complementary supplements like vitamin B6 is recommended for those seeking enhanced relief from anxiety.
Based on user reviews, many individuals highlight the effectiveness of magnesium in managing anxiety, with several suggesting a standard daily dose. There are frequent mentions of users feeling calmer and experiencing reduced anxiety after taking one capsule daily, such as in the case of a review stating, "I've been taking magnesium for years. This particular brand has helped reduce my anxiety... with just one capsule a day" Read Review. Others reported improvements in their anxiety levels after taking magnesium consistently, suggesting that regular intake over time can yield significant benefits for emotional well-being Read Review.
Some users recommend consulting a healthcare provider to determine the right dose, with insights indicating that while 400 mg may be a high dose for some, a lower amount, like 200 mg, could be effective for others, especially in the early stages Read Review. Overall, users report that integration of magnesium into their routines has led to improved mood, reduced anxiety, and better sleep quality, underscoring its potential benefits for those seeking natural anxiety relief.
9
Anxiety reduction success
1 people found this helpful
After starting magnesium, my anxiety decreased within five days. I also began sleeping better, boosting my mood significantly. Living in a stressful environment, magnesium has been a true lifesaver.
9
Reduced anxiety
4 people found this helpful
I take a capsule before bed, and within a week, my anxiety and nervousness vanished. My stress resilience has improved significantly, and my mood has become joyful even on gloomy autumn days. I highly recommend it!
9
Improved calmness
5 people found this helpful
Wonderful! I had a very restless and difficult period, with disturbed sleep and anxiety. I decided to pull myself together and chose this product from iHerb. The effect became noticeable after ten days. Now, I sleep perfectly without interruptions and feel calmer overall.
9
Improved calmness
11 people found this helpful
This excellent supplement relieves muscle tension and anxiety, improving my quality of life over two years. Regular magnesium intake transformed me from a tired person into a calm one. My emotional sensitivity and constant headaches have significantly diminished.
9
Anxiety reduction
5 people found this helpful
I've been aware of magnesium's benefits, and it has helped maintain my nervous system. This supplement quickly alleviated my insomnia and anxiety, allowing me to feel more at ease.
9
Anxiety management
10 people found this helpful
This magnesium product has significantly improved my sleep quality and helped me manage stress better, making me more tolerant in stressful situations. I will continue taking it due to its benefits.
9
Less anxiety experience
9 people found this helpful
This working additive alleviated muscle tension and anxiety, improving my life significantly over two years. I used to be very affected by the weather, but now I feel calmer. Regular magnesium intake is important for avoiding deficiencies.
7.5
Stress reduction
8 people found this helpful
Magnesium is a natural anti-stress supplement that has successfully helped me manage anxiety and improved my sleep quality. I combine it with vitamin B6 and notice the calming effects on my mood.
8
Improved mood
3 people found this helpful
Magnesium has become essential to my routine. I started taking it for muscle spasms and sleep improvement. After a few days, my nighttime cramps disappeared, sleep became deeper, and it also eased my anxiety. I recommend it to anyone needing better sleep and mood.
9
Anxiety management
1 people found this helpful
Upon my neurologist's advice, I've been taking magnesium for years. This particular brand has helped reduce my anxiety, alleviate nervous pain, and improve sleep quality with just one capsule a day.
7.5
Positive psychological state
Excellent, but I suggest consulting your doctor for dosage. It is effective for anxiety and altering the psychological and sleep state, serving as a nerve relaxant. Dosage should be personalised; 400 mg is a high dose. You can opt for one pill every three days or a lower dose of 200 mg or less.
7
Magnesium shows potential for anxiety
Examining the Effects of Supplemental Magnesium on Self-Reported Anxiety and Sleep Quality: A Systematic Review.
We conducted a systematic review to evaluate how magnesium might help with anxiety. As self-treatment with supplements grows in popularity, we focused on the clinical evidence surrounding magnesium’s effects on anxiety and sleep disorders.
Through our thorough search, we found 15 studies that fit our strict criteria. Most of these studies showed at least some improvement in either anxiety levels or sleep quality. In fact, five out of eight studies looking at sleep-related outcomes noted positive changes, while five out of seven studies focused on anxiety reported improvements in self-reported anxiety.
Despite the encouraging findings, we have to approach these results with caution. The studies varied in terms of dosage, formulation, and duration of magnesium treatment. Plus, some included other active ingredients that make it hard to know magnesium’s exact impact. Interestingly, two of the studies that didn’t show improvement involved populations with other health concerns, highlighting the need for further investigation.
Overall, it seems like magnesium might be a useful supplement for those dealing with mild anxiety, especially if they have low magnesium levels to begin with. However, larger and more rigorous trials are essential to truly confirm its effectiveness and determine the best types and doses for use.
7
Magnesium's transient anxiety relief
Probiotics and magnesium orotate for the treatment of major depressive disorder: a randomised double blind controlled trial.
In our quest to understand how magnesium influences anxiety, we conducted a randomized double-blind controlled trial involving 120 adults diagnosed with major depressive disorder (MDD). Participants took either a combination of probiotics, magnesium orotate, and coenzyme Q10 or a placebo for eight weeks.
At the end of the treatment period, we observed that those taking the combination showed significantly lower rates of major depressive episodes compared to those taking the placebo. However, this difference did not persist by the 8-week follow-up. While there was a notable reduction in self-reported symptoms of anxiety and stress during the treatment, this result also lacks long-term significance.
Ultimately, while our findings suggest that magnesium in combination with probiotics and coenzyme Q10 might help alleviate anxiety symptoms for a brief period, the persistent effects are unclear as we found no enduring benefits in the longer term.
7
Magnesium affects anxiety via gut bacteria
Magnesium Oxide Reduces Anxiety-like Behavior in Mice by Inhibiting Sulfate-Reducing Bacteria.
We examined the link between magnesium oxide and anxiety-like behavior in mice. The research focused on how a specific type of bacteria in the gut, known as sulfate-reducing bacteria (SRB), might contribute to anxiety. When we introduced these bacteria into the mice, they exhibited increased signs of anxiety, which we measured using a test called the open field test.
Next, we explored the effect of magnesium oxide on the growth of these bacteria in both lab settings and in real-life scenarios involving psychological stress, specifically using a water avoidance stress model. Remarkably, we found that magnesium oxide effectively inhibited the growth of SRB and the production of a byproduct called hydrogen sulfide in a dose-dependent manner.
Mice subjected to stress developed an overgrowth of SRB and displayed amplified anxiety-like behavior. However, those fed a magnesium oxide-enriched diet showed reduced levels of both SRB and anxiety. Our findings suggest that magnesium may play a significant role in mitigating anxiety by altering gut bacteria dynamics.
8
Magnesium reduces anxiety symptoms
Neuroprotective effects of magnesium against stress induced by hydrogen peroxide in Wistar rat.
We investigated how magnesium might influence anxiety, particularly when triggered by oxidative stress from hydrogen peroxide. The study involved eighteen Wistar rats divided into three groups: a control group, a group treated with hydrogen peroxide, and a group receiving both hydrogen peroxide and magnesium sulphate.
Our findings revealed that the rats exposed to hydrogen peroxide exhibited increased anxiety and signs of oxidative damage in the brain. However, those that received magnesium showed significant improvements. They not only had reduced levels of anxiety but also demonstrated less oxidative stress.
This suggests that magnesium could play a beneficial role in counteracting anxiety and the negative effects of oxidative stress. Though the results are promising, it's important to remember that further research is needed to fully understand magnesium's potential effects on anxiety in humans.
References
Strodl E, Bambling M, Parnam S, Ritchie G, Cramb S, et al. Probiotics and magnesium orotate for the treatment of major depressive disorder: a randomised double blind controlled trial. Sci Rep. 2024;14:20841. 10.1038/s41598-024-71093-z
Coffman CN, Carroll-Portillo A, Alcock J, Singh SB, Rumsey K, et al. Magnesium Oxide Reduces Anxiety-like Behavior in Mice by Inhibiting Sulfate-Reducing Bacteria. Microorganisms. 2024;12. 10.3390/microorganisms12071429
Rawji A, Peltier MR, Mourtzanakis K, Awan S, Rana J, et al. Examining the Effects of Supplemental Magnesium on Self-Reported Anxiety and Sleep Quality: A Systematic Review. Cureus. 2024;16:e59317. 10.7759/cureus.59317
Wang S, Zhang J, Zhu T, Xie X, Xia X, et al. Efficacy of Magnesium Sulfate and Labetalol in the Treatment of Pregnancy-Induced Hypertension and Its Effect on Anxiety and Depression: A Retrospective Cohort Study. Alpha Psychiatry. 2024;25:243. 10.5152/alphapsychiatry.2024.231342
Abdel Rady MM, Osman AM, Abo Elfadl GM, Ahmed HM, Sayed S, et al. Effects of intravenous single-bolus lidocaine infusion versus intravenous single-bolus magnesium sulfate infusion on postoperative pain, emotional status, and quality of life in patients undergoing spine fusion surgery: a randomized study. Minerva Anestesiol. 2024;90:397. 10.23736/S0375-9393.24.17868-6
Cetin A, Ozdemir E, Golgeli A, Taskiran AS, Karabulut S, et al. The effect of magnesium sulfate on memory and anxiety-like behavior in a rat model: an investigation of its neuronal molecular mechanisms. Neurol Res. 2024;46:752. 10.1080/01616412.2024.2352234
Mititelu-Tartau L, Bogdan M, Pavel LL, Rezus C, Foia CI, et al. Anxiolytic-like Activity, Antioxidant Properties, and Facilitatory Effects on the Short-Term Memory Retention of Molsidomine in Rats. Life (Basel). 2024;14. 10.3390/life14030306
Cherian KN, Keynan JN, Anker L, Faerman A, Brown RE, et al. Magnesium-ibogaine therapy in veterans with traumatic brain injuries. Nat Med. 2024;30:373. 10.1038/s41591-023-02705-w
Pickering G, Noah L, Pereira B, Goubayon J, Leray V, et al. Assessing brain function in stressed healthy individuals following the use of a combination of green tea, Rhodiola, magnesium, and B vitamins: an fMRI study. Front Nutr. 2023;10:1211321. 10.3389/fnut.2023.1211321
Hajri L, Othman H, Ghodbane S, Sakly M, Abdelmelek H, et al. Neuroprotective effects of magnesium against stress induced by hydrogen peroxide in Wistar rat. Biomarkers. 2023;28:538. 10.1080/1354750X.2023.2246104
Li Z, Chen K, Shao Q, Lu H, Zhang X, et al. Nanoparticulate MgH ameliorates anxiety/depression-like behaviors in a mouse model of multiple sclerosis by regulating microglial polarization and oxidative stress. J Neuroinflammation. 2023;20:16. 10.1186/s12974-023-02696-y
Proskurnina EV, Liaukovich KM, Bychkovskaya LS, Mikheev IV, Alshanskaia EI, et al. Salivary Antioxidant Capacity and Magnesium in Generalized Anxiety Disorder. Metabolites. 2023;13. 10.3390/metabo13010073