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NOW Supplements P-5-P
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Good
Based on 2 Reviews
8.5
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Vitamin B-6 [from 50 mg Coenzyme Pyridoxal-5-Phosphate (P-5-P) Monohydrate]
33 mg
1941%
Magnesium (from Magnesium Bisglycinate) (TRAACS®)
25 mg
6%

Top Medical Research Studies

8
Vitamin B6 improves IBS symptoms
Effects of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001 in IBS patients.
Relevant but not isolated effect.
We conducted a controlled trial involving twenty-five patients diagnosed with Irritable Bowel Syndrome (IBS) to explore the effects of a unique combination of probiotics—Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001—along with vitamin B6 on gastrointestinal symptoms, particularly bloating.

Over a period of two months, we randomly assigned patients to receive either the probiotic combination with vitamin B6 or a placebo, ensuring that the study design was double-blind to eliminate bias. Throughout the study, we assessed symptoms, including abdominal pain and bloating, as well as the overall severity of IBS.

Remarkably, our findings revealed that the probiotic formulation significantly reduced bloating, showing a decrease of 36.35% compared to a slight increase with the placebo. This improvement also corresponded with reduced abdominal pain and improved intestinal health indicators. The probiotics not only alleviated bloating but also favored a healthier balance of gut bacteria, suggesting a positive overall impact on the IBS patients’ digestive wellness.

Although we cannot attribute effects solely to vitamin B6 since it was used in combination with probiotics, the results indicate that this formulation can improve symptoms associated with bloating and overall IBS severity. Thus, our study illuminates a potential approach for better managing IBS symptoms without relying solely on traditional medications.
Read More
8
Vitamin B6 alleviates bloating symptoms
Effects of and on Gut Microbiota in Patients with Lactose Intolerance and Persisting Functional Gastrointestinal Symptoms: A Randomised, Double-Blind, Cross-Over Study.
Study shows significant bloating reduction
We conducted a randomized, double-blind, cross-over study to evaluate how vitamin B6, alongside probiotics, affects bloating in lactose intolerant individuals experiencing ongoing gastrointestinal symptoms despite following a lactose-free diet.

In our study involving 23 participants, we compared a combination treatment of probiotics and vitamin B6 to a placebo. The results were promising: participants who received the probiotic and vitamin B6 treatment reported a significant decrease in bloating. We saw a p-value of 0.028, which suggests that the treatment had a notable effect.

Additionally, we noticed changes in gut microbiota, with the supplementation encouraging the growth of beneficial bacteria, such as Bifidobacterium, which plays a key role in lactose digestion. This means not only did vitamin B6 appear to ease bloating, but it also helped improve the overall gut environment for those struggling with lactose intolerance.

Overall, our findings indicate that combining probiotics with vitamin B6 could provide relief for lactose intolerant patients dealing with persistent digestive issues, particularly bloating. This is good news for individuals looking for ways to enhance their gut health and manage their symptoms more effectively.
Read More

Most Useful Reviews

8.8
Reduces bloating
Vitamin B6 (pyridoxine) is essential for over 100 enzymatic reactions in the body, including protein synthesis and the regulation of blood sugar levels. It is also important for the metabolism of estrogen and the production of key neurotransmitters like dopamine and adrenaline, along with detoxification processes involving glutathione. This vitamin can alleviate bloating and discomfort during the luteal phase (two weeks before menstruation) and help relieve PMS symptoms. Additionally, it may assist with low mood resulting from dietary deficiencies in this vitamin.
Read More
8
Controls bloating
Seems to keep my gut issues in check. When I stop taking it, I bloat again. Always arrives on time.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
  • All Researches
8
Vitamin B6 improves IBS symptoms
Effects of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001 in IBS patients.
Relevant but not isolated effect.
We conducted a controlled trial involving twenty-five patients diagnosed with Irritable Bowel Syndrome (IBS) to explore the effects of a unique combination of probiotics—Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001—along with vitamin B6 on gastrointestinal symptoms, particularly bloating.

Over a period of two months, we randomly assigned patients to receive either the probiotic combination with vitamin B6 or a placebo, ensuring that the study design was double-blind to eliminate bias. Throughout the study, we assessed symptoms, including abdominal pain and bloating, as well as the overall severity of IBS.

Remarkably, our findings revealed that the probiotic formulation significantly reduced bloating, showing a decrease of 36.35% compared to a slight increase with the placebo. This improvement also corresponded with reduced abdominal pain and improved intestinal health indicators. The probiotics not only alleviated bloating but also favored a healthier balance of gut bacteria, suggesting a positive overall impact on the IBS patients’ digestive wellness.

Although we cannot attribute effects solely to vitamin B6 since it was used in combination with probiotics, the results indicate that this formulation can improve symptoms associated with bloating and overall IBS severity. Thus, our study illuminates a potential approach for better managing IBS symptoms without relying solely on traditional medications.
Read More
8
Vitamin B6 alleviates bloating symptoms
Effects of and on Gut Microbiota in Patients with Lactose Intolerance and Persisting Functional Gastrointestinal Symptoms: A Randomised, Double-Blind, Cross-Over Study.
Study shows significant bloating reduction
We conducted a randomized, double-blind, cross-over study to evaluate how vitamin B6, alongside probiotics, affects bloating in lactose intolerant individuals experiencing ongoing gastrointestinal symptoms despite following a lactose-free diet.

In our study involving 23 participants, we compared a combination treatment of probiotics and vitamin B6 to a placebo. The results were promising: participants who received the probiotic and vitamin B6 treatment reported a significant decrease in bloating. We saw a p-value of 0.028, which suggests that the treatment had a notable effect.

Additionally, we noticed changes in gut microbiota, with the supplementation encouraging the growth of beneficial bacteria, such as Bifidobacterium, which plays a key role in lactose digestion. This means not only did vitamin B6 appear to ease bloating, but it also helped improve the overall gut environment for those struggling with lactose intolerance.

Overall, our findings indicate that combining probiotics with vitamin B6 could provide relief for lactose intolerant patients dealing with persistent digestive issues, particularly bloating. This is good news for individuals looking for ways to enhance their gut health and manage their symptoms more effectively.
Read More

User Reviews

USERS' SCORE
Good
Based on 2 Reviews
8.5
  • All Reviews
  • Positive Reviews
  • Negative Reviews
8.8
Reduces bloating
Vitamin B6 (pyridoxine) is essential for over 100 enzymatic reactions in the body, including protein synthesis and the regulation of blood sugar levels. It is also important for the metabolism of estrogen and the production of key neurotransmitters like dopamine and adrenaline, along with detoxification processes involving glutathione. This vitamin can alleviate bloating and discomfort during the luteal phase (two weeks before menstruation) and help relieve PMS symptoms. Additionally, it may assist with low mood resulting from dietary deficiencies in this vitamin.
Read More
8
Controls bloating
Seems to keep my gut issues in check. When I stop taking it, I bloat again. Always arrives on time.
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