' 
SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.5
USERS' SCORE
Excellent
Based on 17 Reviews
9
Supplement Facts
Serving Size: 2 Veg Capsules
Amount Per Serving
%DV
Saccharomyces boulardii (10 Billion CFU)(Saccharomyces cerevisiae var. boulardii I-3799)
1,000 mg
**
Top Medical Research Studies
9.5
Targeted probiotic shows promise
Targeted delivery of the probiotic Saccharomyces boulardii to the extracellular matrix enhances gut residence time and recovery in murine colitis.
High relevance to colitis treatment
We explored the effectiveness of a specially engineered probiotic yeast, Saccharomyces boulardii, aimed at treating colitis. By cleverly binding this probiotic to proteins in the gut, we managed to significantly extend its stay in the gastrointestinal tract. This allowed us to observe a noteworthy increase in probiotic levels in the colon.
Importantly, our findings showed improvements in critical health markers, such as colon length and inflammation scores. This innovative approach suggests that targeted probiotics could be a game changer in managing inflammatory bowel diseases.
Importantly, our findings showed improvements in critical health markers, such as colon length and inflammation scores. This innovative approach suggests that targeted probiotics could be a game changer in managing inflammatory bowel diseases.
Read More
9
Saccharomyces boulardii reduces colitis cancer
Saccharomyces boulardii alleviates ulcerative colitis carcinogenesis in mice by reducing TNF-α and IL-6 levels and functions and by rebalancing intestinal microbiota.
Highly relevant for understanding treatment
We examined how Saccharomyces boulardii impacts ulcerative colitis and its related cancer development in mice. In this study, mice underwent a specific treatment to create a model of ulcerative colitis, followed by 12 weeks of S. boulardii treatment.
The results showed a significant reduction in tumor development as well as lower levels of inflammatory markers, TNF-α and IL-6. Additionally, S. boulardii positively influenced the composition of intestinal bacteria. Overall, the findings suggest that saccharomyces boulardii may have protective effects against colitis-related cancer.
The results showed a significant reduction in tumor development as well as lower levels of inflammatory markers, TNF-α and IL-6. Additionally, S. boulardii positively influenced the composition of intestinal bacteria. Overall, the findings suggest that saccharomyces boulardii may have protective effects against colitis-related cancer.
Read More
9
Saccharomyces boulardii's effects on colitis
protects against murine experimental colitis by reshaping the gut microbiome and its metabolic profile.
High relevance for gut health study
We investigated whether Saccharomyces boulardii could protect mice from experimental colitis. Over three weeks, treated mice showed less weight loss, reduced colon damage, and improved gut barrier function compared to untreated ones.
By promoting beneficial bacteria and reducing harmful ones, it enhanced microbial diversity and transformed the gut's metabolite profile. These beneficial changes correlated with lower inflammation, suggesting that S. boulardii might be a promising treatment option for colitis based on its effects on gut health.
By promoting beneficial bacteria and reducing harmful ones, it enhanced microbial diversity and transformed the gut's metabolite profile. These beneficial changes correlated with lower inflammation, suggesting that S. boulardii might be a promising treatment option for colitis based on its effects on gut health.
Read More
Most Useful Reviews
9.5
Frequent flare-ups eased
I have suffered from ulcerative colitis for 25 years, experiencing frequent flare-ups that typically required steroids for relief. In recent years, flare-ups have grown more common, but I found that avoiding gluten and dairy helped. Eventually, they returned almost weekly. However, since starting this once a day, there has been significant improvement; I've remained flare-up free for two months now. I can enjoy all the vegetables I like without worrying about soft stools. I've reduced my colitis medication dosage and use this as daily maintenance alongside it. I have never felt so liberated from the bonds of colitis; this stuff truly works.
Read More
9.5
Effective for colitis
Boulardii was crucial for managing my activated ulcerative colitis, which Gr8-Dophilus alone couldn't handle. Two years ago, a combination of Boulardii, a gluten-free diet, and other products saved my colon from surgery. Unfortunately, my colon deteriorated again, preventing adequate good bacteria growth. Thankfully, Boulardii worked its magic once again.
Read More
9.5
Colitis relief found
Fast delivery, thank you! These saccharomycetes saved me when I developed pseudomembranous colitis after several antibiotic courses. Nothing helped me, except for Saccharomyces Boulardii, which was a lifesaver.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.5
- All Researches
9.5
Targeted probiotic shows promise
Targeted delivery of the probiotic Saccharomyces boulardii to the extracellular matrix enhances gut residence time and recovery in murine colitis.
High relevance to colitis treatment
We explored the effectiveness of a specially engineered probiotic yeast, Saccharomyces boulardii, aimed at treating colitis. By cleverly binding this probiotic to proteins in the gut, we managed to significantly extend its stay in the gastrointestinal tract. This allowed us to observe a noteworthy increase in probiotic levels in the colon.
Importantly, our findings showed improvements in critical health markers, such as colon length and inflammation scores. This innovative approach suggests that targeted probiotics could be a game changer in managing inflammatory bowel diseases.
Importantly, our findings showed improvements in critical health markers, such as colon length and inflammation scores. This innovative approach suggests that targeted probiotics could be a game changer in managing inflammatory bowel diseases.
Read More
9
Probiotic shows anti-inflammatory efficacy
Efficient surface display of single-chain variable fragments against tumor necrosis factor α on engineered probiotic Saccharomyces boulardii and its application in alleviating intestinal inflammation in vivo.
High relevance for gut health
We explored the potential of Saccharomyces boulardii, a probiotic, to ease gut inflammation. This study developed a unique system that displayed specific anti-inflammatory proteins on the probiotic. By optimizing these proteins' expression, the engineered S. boulardii samples were tested on a colitis mouse model.
The results indicated a notably lower disease activity and a reduction in inflammation markers, suggesting that this innovative approach could be effective in improving intestinal health. Overall, our findings highlight the probiotic's promise in managing inflammatory conditions.
The results indicated a notably lower disease activity and a reduction in inflammation markers, suggesting that this innovative approach could be effective in improving intestinal health. Overall, our findings highlight the probiotic's promise in managing inflammatory conditions.
Read More
9
Saccharomyces boulardii as a postbiotic
A Saccharomyces boulardii-derived antioxidant protein, thioredoxin, ameliorates intestinal inflammation through transactivating epidermal growth factor receptor.
Study demonstrates therapeutic potential
We explored the impact of Saccharomyces boulardii on colitis, aiming to understand its potential benefits for gut health. Our findings revealed that an oral dose of S. boulardii supernatant helped ease intestinal inflammation and reinforced the gut barrier.
A key player in this process is thioredoxin (Trx), a protein that activated important pathways to reduce inflammation and oxidative stress. By promoting the activation of the epidermal growth factor receptor, Trx showed promise as a new postbiotic treatment for colitis.
However, while these results are encouraging, more research is needed to fully comprehend its long-term effects.
A key player in this process is thioredoxin (Trx), a protein that activated important pathways to reduce inflammation and oxidative stress. By promoting the activation of the epidermal growth factor receptor, Trx showed promise as a new postbiotic treatment for colitis.
However, while these results are encouraging, more research is needed to fully comprehend its long-term effects.
Read More
9
Heat-killed Saccharomyces boulardii benefits UC
Heat-Killed Alleviates Dextran Sulfate Sodium-Induced Ulcerative Colitis by Restoring the Intestinal Barrier, Reducing Inflammation, and Modulating the Gut Microbiota.
Relevant potential treatment evaluation
This study delved into the effects of heat-killed Saccharomyces boulardii on ulcerative colitis, aiming to uncover its potential as a treatment option. We observed that this treatment significantly restored body weight, reduced inflammation, and improved gut barrier function in mice with colitis. It also effectively modulated gut microbiota, outperforming other treatments like β-glucan.
Overall, heat-killed Saccharomyces boulardii presents a promising new approach for those suffering from ulcerative colitis, enhancing their quality of life.
Overall, heat-killed Saccharomyces boulardii presents a promising new approach for those suffering from ulcerative colitis, enhancing their quality of life.
Read More
9
Saccharomyces boulardii's effects on colitis
protects against murine experimental colitis by reshaping the gut microbiome and its metabolic profile.
High relevance for gut health study
We investigated whether Saccharomyces boulardii could protect mice from experimental colitis. Over three weeks, treated mice showed less weight loss, reduced colon damage, and improved gut barrier function compared to untreated ones.
By promoting beneficial bacteria and reducing harmful ones, it enhanced microbial diversity and transformed the gut's metabolite profile. These beneficial changes correlated with lower inflammation, suggesting that S. boulardii might be a promising treatment option for colitis based on its effects on gut health.
By promoting beneficial bacteria and reducing harmful ones, it enhanced microbial diversity and transformed the gut's metabolite profile. These beneficial changes correlated with lower inflammation, suggesting that S. boulardii might be a promising treatment option for colitis based on its effects on gut health.
Read More
User Reviews
USERS' SCORE
Excellent
Based on 17 Reviews
9
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Frequent flare-ups eased
I have suffered from ulcerative colitis for 25 years, experiencing frequent flare-ups that typically required steroids for relief. In recent years, flare-ups have grown more common, but I found that avoiding gluten and dairy helped. Eventually, they returned almost weekly. However, since starting this once a day, there has been significant improvement; I've remained flare-up free for two months now. I can enjoy all the vegetables I like without worrying about soft stools. I've reduced my colitis medication dosage and use this as daily maintenance alongside it. I have never felt so liberated from the bonds of colitis; this stuff truly works.
Read More
9.5
Effective for colitis
Boulardii was crucial for managing my activated ulcerative colitis, which Gr8-Dophilus alone couldn't handle. Two years ago, a combination of Boulardii, a gluten-free diet, and other products saved my colon from surgery. Unfortunately, my colon deteriorated again, preventing adequate good bacteria growth. Thankfully, Boulardii worked its magic once again.
Read More
9.5
Colitis relief found
Fast delivery, thank you! These saccharomycetes saved me when I developed pseudomembranous colitis after several antibiotic courses. Nothing helped me, except for Saccharomyces Boulardii, which was a lifesaver.
8.8
Notable difference experienced
Great for sufferers of colitis, made a noticeable difference!
9.5
Tremendous symptom relief
Brilliant! Along with probiotics, my Ulcerative Colitis symptoms have improved tremendously, and I haven’t needed any prescription medication for a while now. I will keep using these as they have been amazing for me.
