Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
USERS' SCORE
Good
Based on 8 Reviews
8.2
Supplement Facts
Serving Size: 2 Veg Capsules
Amount Per Serving
%DV
Calories
5
 
Total Carbohydrate
1 g
<1%**
Milk Thistle Extract (Silybum marianum)(Fruit/Seeds) (Standardized to 240 mg Silymarin Flavonoids - equivalent 80%) 
300 mg
Turmeric (Curcuma longa) (Root)
700 mg

Top Medical Research Studies

9
Milk thistle shows anti-psoriatic effects
We investigated how milk thistle extract might help treat psoriasis in mice. Our study involved forty Swiss albino mice divided into four groups, including a test group treated with the milk thistle extract after inducing psoriasis with imiquimod.

The results were encouraging, showing that the extract significantly reduced skin symptoms like redness and scaling, similar to traditional cortisone treatments. It worked by inhibiting specific cellular pathways, reducing inflammation and boosting antioxidant defenses, suggesting that milk thistle could be an effective new option for psoriasis treatment.
Read More
8
Silymarin alleviates psoriasis lesions
We investigated the effects of silymarin, a natural compound from milk thistle, on psoriasis in a mouse model. Employing a robust approach that evaluated specific signaling pathways, we found that silymarin significantly targets the TGF-β1/miR-21 pathway.

This treatment not only blocked harmful cell cycle progression and reduced keratinocyte differentiation but also alleviated inflammation. Our findings suggest that silymarin promotes healthier skin by regulating lipid synthesis and inflammatory responses, pointing to its potential as a supportive therapy for psoriasis.
Read More

Most Useful Reviews

9.5
Effective psoriasis treatment
This supplement works wonders for my psoriasis! I've been taking it since May 2013, and it has significantly improved my condition. If I follow the instructed dosage, my blood pressure elevates excessively, so I only take two pills each morning and use an oily cream at night. The progress is slow, but at this rate, I anticipate being completely psoriasis-free by next summer!
Read More
8.8
Relieves psoriasis flare-ups
I found this product effective for my psoriasis. After taking it twice with a one-month break, alongside a B-complex vitamin, I noticed improvement after about three weeks. I also shared it with my husband, who mentioned that he experienced no hangover effects from silymarin.
Read More
8.8
Aids hepatic function
I bought it for my parents during a course. My mother experienced psoriasis flare-ups, and when she concentrated on her liver health by taking silymarin and other pharmaceuticals, it did help. However, the effects weren't immediate.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
  • All Researches
9
Milk thistle shows anti-psoriatic effects
We investigated how milk thistle extract might help treat psoriasis in mice. Our study involved forty Swiss albino mice divided into four groups, including a test group treated with the milk thistle extract after inducing psoriasis with imiquimod.

The results were encouraging, showing that the extract significantly reduced skin symptoms like redness and scaling, similar to traditional cortisone treatments. It worked by inhibiting specific cellular pathways, reducing inflammation and boosting antioxidant defenses, suggesting that milk thistle could be an effective new option for psoriasis treatment.
Read More
8
Silymarin alleviates psoriasis lesions
We investigated the effects of silymarin, a natural compound from milk thistle, on psoriasis in a mouse model. Employing a robust approach that evaluated specific signaling pathways, we found that silymarin significantly targets the TGF-β1/miR-21 pathway.

This treatment not only blocked harmful cell cycle progression and reduced keratinocyte differentiation but also alleviated inflammation. Our findings suggest that silymarin promotes healthier skin by regulating lipid synthesis and inflammatory responses, pointing to its potential as a supportive therapy for psoriasis.
Read More

User Reviews

USERS' SCORE
Good
Based on 8 Reviews
8.2
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Effective psoriasis treatment
This supplement works wonders for my psoriasis! I've been taking it since May 2013, and it has significantly improved my condition. If I follow the instructed dosage, my blood pressure elevates excessively, so I only take two pills each morning and use an oily cream at night. The progress is slow, but at this rate, I anticipate being completely psoriasis-free by next summer!
Read More
8.8
Relieves psoriasis flare-ups
I found this product effective for my psoriasis. After taking it twice with a one-month break, alongside a B-complex vitamin, I noticed improvement after about three weeks. I also shared it with my husband, who mentioned that he experienced no hangover effects from silymarin.
Read More
8.8
Aids hepatic function
I bought it for my parents during a course. My mother experienced psoriasis flare-ups, and when she concentrated on her liver health by taking silymarin and other pharmaceuticals, it did help. However, the effects weren't immediate.
Read More
8.8
Visible psoriasis improvement
After my psoriasis worsened and I developed acne, I saw results within a week. My skin started to clear up, and my overall health improved, including digestive regularity.
Read More
5.8
Cleansing remedy for psoriasis
We choose another product from the same brand. We use Now Foods, Silymarin, Milk Thistle Extract. It's an effective cleansing remedy, especially for those with psoriasis. I recommend starting the treatment after the full moon, as the body tends to detoxify more effectively during the waning moon.
Read More

Frequently Asked Questions

No FAQs are available for this product and symptom.

References

  1. Kamel NM, El-Sayed SS, El-Said YAM, El-Kersh DM, Hashem MM, et al. Unlocking milk thistle's anti-psoriatic potential in mice: Targeting PI3K/AKT/mTOR and KEAP1/NRF2/NF-κB pathways to modulate inflammation and oxidative stress. Int Immunopharmacol. 2024;139:112781. doi:10.1016/j.intimp.2024.112781
  2. Henriet E, Abdallah F, Laurent Y, Guimpied C, Clement E, et al. Targeting TGF-β1/miR-21 Pathway in Keratinocytes Reveals Protective Effects of Silymarin on Imiquimod-Induced Psoriasis Mouse Model. JID Innov. 2023;3:100175. doi:10.1016/j.xjidi.2022.100175
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