' 
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.3
USERS' SCORE
Good
Based on 2 Reviews
8.7
Supplement Facts
Serving Size: 2 Capsules
Amount Per Serving
%DV
Calcium (elemental)(from 2,273 mg MCHA)**
500 mg
38%
Phosphorus (elemental)(from 2,273 mg MCHA)**
200 mg
16%
Top Medical Research Studies
7
Calcium treatment impacts cancer viability
Investigation of the Bystander Effect on Cell Viability After Application of Combined Electroporation-Based Methods.
Calcium relevance in cancer treatment
We investigated how calcium treatment, in conjunction with various electroporation methods, affects cancer cell viability. In our study, we used 4T1 breast cancer cells and applied different forms of electroporation, such as reversible and irreversible treatments along with calcium electroporation. We were particularly interested in the bystander effect, where treated cells might affect untreated nearby cells.
By transferring conditioned media from the treated to untreated cells, we observed significant impacts on cell viability. The results showed that after applying calcium electroporation and bleomycin treatments, colony formation plummeted to nearly zero, and metabolic activity dipped as low as 11.62%. Additionally, other assessments, including flow cytometry, confirmed a drastic decrease in cell viability in the presence of calcium therapy.
While the study highlighted calcium’s role in enhancing the effects of electroporation, the combined treatments reduced the overall viability of surrounding cells markedly. We also noticed a delay in wound healing with conditioned media, indicating that calcium treatment could significantly impact not just treated but also neighboring cancer cells. Overall, calcium's combined effects were powerful, emphasizing its utility in cancer treatment strategies.
By transferring conditioned media from the treated to untreated cells, we observed significant impacts on cell viability. The results showed that after applying calcium electroporation and bleomycin treatments, colony formation plummeted to nearly zero, and metabolic activity dipped as low as 11.62%. Additionally, other assessments, including flow cytometry, confirmed a drastic decrease in cell viability in the presence of calcium therapy.
While the study highlighted calcium’s role in enhancing the effects of electroporation, the combined treatments reduced the overall viability of surrounding cells markedly. We also noticed a delay in wound healing with conditioned media, indicating that calcium treatment could significantly impact not just treated but also neighboring cancer cells. Overall, calcium's combined effects were powerful, emphasizing its utility in cancer treatment strategies.
Read More
4
Calcium's role in cancer dynamics
Calcium levels modulate platelet function, platelet-cancer cell interaction, and cancer cell invasion.
Moderate relevance to cancer research
We examined how calcium levels impact the interactions between platelets and cancer cells, as these interactions are crucial for cancer metastasis. Our focus was on specific platelet receptors called integrins, which play vital roles in these interactions.
Throughout our study, we discovered that calcium significantly affects the functionality of these integrins and the overall behavior of platelets. When we reduced calcium levels, we noticed a change in how platelets interacted with breast cancer cells (specifically MDA-MB-231). On the contrary, environments with high calcium levels did not seem to affect these interactions as significantly.
Interestingly, we observed that hypercalcemia, or elevated calcium levels, appeared to enhance cancer cell invasion in the presence of platelets for both breast and lung cancer cells (MDA-MB-231 and A549, respectively). This suggests that rather than obstructing metastatic processes, high calcium may facilitate cancer spread, offering a new perspective on calcium's role in cancer dynamics.
Overall, this study sheds light on how calcium adjustments could be viewed not only as a potential therapeutic strategy but also as a factor impacting cancer progression, especially through platelet interactions.
Throughout our study, we discovered that calcium significantly affects the functionality of these integrins and the overall behavior of platelets. When we reduced calcium levels, we noticed a change in how platelets interacted with breast cancer cells (specifically MDA-MB-231). On the contrary, environments with high calcium levels did not seem to affect these interactions as significantly.
Interestingly, we observed that hypercalcemia, or elevated calcium levels, appeared to enhance cancer cell invasion in the presence of platelets for both breast and lung cancer cells (MDA-MB-231 and A549, respectively). This suggests that rather than obstructing metastatic processes, high calcium may facilitate cancer spread, offering a new perspective on calcium's role in cancer dynamics.
Overall, this study sheds light on how calcium adjustments could be viewed not only as a potential therapeutic strategy but also as a factor impacting cancer progression, especially through platelet interactions.
Read More
8
Calcium-Vitamin D benefits post-surgery
Effects of vitamin D and calcium supplementation on bone of young adults after thyroidectomy of differentiated thyroid carcinoma.
Moderate relevance to calcium effects
We explored the impact of calcium and vitamin D supplementation on bone health in young adults after surgery for differentiated thyroid carcinoma (DTC). This study focused on patients under 50 years who had thyroidectomy and were experiencing vitamin D deficiency or insufficiency.
Over the course of one year, we provided patients with daily calcium and vitamin D supplements, monitoring their bone metabolism along the way. After analyzing results from 458 patients, we found that those receiving the supplements had lower levels of parathyroid hormone (PTH) and a notable increase in bone mineral density (BMD) at both the lumbar spine and hip compared to those who did not receive any supplements.
Our findings suggest that calcium, combined with vitamin D, can play a beneficial role in reducing bone loss in young DTC patients suffering from vitamin D malnutrition after thyroid surgery. This could mean improved bone health and a reduced risk of osteoporosis for these patients in the future.
Over the course of one year, we provided patients with daily calcium and vitamin D supplements, monitoring their bone metabolism along the way. After analyzing results from 458 patients, we found that those receiving the supplements had lower levels of parathyroid hormone (PTH) and a notable increase in bone mineral density (BMD) at both the lumbar spine and hip compared to those who did not receive any supplements.
Our findings suggest that calcium, combined with vitamin D, can play a beneficial role in reducing bone loss in young DTC patients suffering from vitamin D malnutrition after thyroid surgery. This could mean improved bone health and a reduced risk of osteoporosis for these patients in the future.
Read More
Most Useful Reviews
9.5
Significant improvement
I ordered this calcium for my sister when she had cancer, based on a doctor's recommendation. To be honest, it helped her immensely, and it works best when taken alongside omega 3.
Read More
9.5
Health improvement noted
I’ve been giving this calcium to my mother for three years and find it excellent. She had thyroid cancer, and due to hormone treatments and age, her calcium levels were depleting. The endocrinologist suggested this specific form. After reading reviews, we ordered it, and after a course of use, we noted significant improvements in her health. The drug's effect was remarkable, and her calcium deficiencies were resolved after six months.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.3
- All Researches
8
Calcium-Vitamin D benefits post-surgery
Effects of vitamin D and calcium supplementation on bone of young adults after thyroidectomy of differentiated thyroid carcinoma.
Moderate relevance to calcium effects
We explored the impact of calcium and vitamin D supplementation on bone health in young adults after surgery for differentiated thyroid carcinoma (DTC). This study focused on patients under 50 years who had thyroidectomy and were experiencing vitamin D deficiency or insufficiency.
Over the course of one year, we provided patients with daily calcium and vitamin D supplements, monitoring their bone metabolism along the way. After analyzing results from 458 patients, we found that those receiving the supplements had lower levels of parathyroid hormone (PTH) and a notable increase in bone mineral density (BMD) at both the lumbar spine and hip compared to those who did not receive any supplements.
Our findings suggest that calcium, combined with vitamin D, can play a beneficial role in reducing bone loss in young DTC patients suffering from vitamin D malnutrition after thyroid surgery. This could mean improved bone health and a reduced risk of osteoporosis for these patients in the future.
Over the course of one year, we provided patients with daily calcium and vitamin D supplements, monitoring their bone metabolism along the way. After analyzing results from 458 patients, we found that those receiving the supplements had lower levels of parathyroid hormone (PTH) and a notable increase in bone mineral density (BMD) at both the lumbar spine and hip compared to those who did not receive any supplements.
Our findings suggest that calcium, combined with vitamin D, can play a beneficial role in reducing bone loss in young DTC patients suffering from vitamin D malnutrition after thyroid surgery. This could mean improved bone health and a reduced risk of osteoporosis for these patients in the future.
Read More
7
Calcium treatment impacts cancer viability
Investigation of the Bystander Effect on Cell Viability After Application of Combined Electroporation-Based Methods.
Calcium relevance in cancer treatment
We investigated how calcium treatment, in conjunction with various electroporation methods, affects cancer cell viability. In our study, we used 4T1 breast cancer cells and applied different forms of electroporation, such as reversible and irreversible treatments along with calcium electroporation. We were particularly interested in the bystander effect, where treated cells might affect untreated nearby cells.
By transferring conditioned media from the treated to untreated cells, we observed significant impacts on cell viability. The results showed that after applying calcium electroporation and bleomycin treatments, colony formation plummeted to nearly zero, and metabolic activity dipped as low as 11.62%. Additionally, other assessments, including flow cytometry, confirmed a drastic decrease in cell viability in the presence of calcium therapy.
While the study highlighted calcium’s role in enhancing the effects of electroporation, the combined treatments reduced the overall viability of surrounding cells markedly. We also noticed a delay in wound healing with conditioned media, indicating that calcium treatment could significantly impact not just treated but also neighboring cancer cells. Overall, calcium's combined effects were powerful, emphasizing its utility in cancer treatment strategies.
By transferring conditioned media from the treated to untreated cells, we observed significant impacts on cell viability. The results showed that after applying calcium electroporation and bleomycin treatments, colony formation plummeted to nearly zero, and metabolic activity dipped as low as 11.62%. Additionally, other assessments, including flow cytometry, confirmed a drastic decrease in cell viability in the presence of calcium therapy.
While the study highlighted calcium’s role in enhancing the effects of electroporation, the combined treatments reduced the overall viability of surrounding cells markedly. We also noticed a delay in wound healing with conditioned media, indicating that calcium treatment could significantly impact not just treated but also neighboring cancer cells. Overall, calcium's combined effects were powerful, emphasizing its utility in cancer treatment strategies.
Read More
4
Calcium's role in cancer dynamics
Calcium levels modulate platelet function, platelet-cancer cell interaction, and cancer cell invasion.
Moderate relevance to cancer research
We examined how calcium levels impact the interactions between platelets and cancer cells, as these interactions are crucial for cancer metastasis. Our focus was on specific platelet receptors called integrins, which play vital roles in these interactions.
Throughout our study, we discovered that calcium significantly affects the functionality of these integrins and the overall behavior of platelets. When we reduced calcium levels, we noticed a change in how platelets interacted with breast cancer cells (specifically MDA-MB-231). On the contrary, environments with high calcium levels did not seem to affect these interactions as significantly.
Interestingly, we observed that hypercalcemia, or elevated calcium levels, appeared to enhance cancer cell invasion in the presence of platelets for both breast and lung cancer cells (MDA-MB-231 and A549, respectively). This suggests that rather than obstructing metastatic processes, high calcium may facilitate cancer spread, offering a new perspective on calcium's role in cancer dynamics.
Overall, this study sheds light on how calcium adjustments could be viewed not only as a potential therapeutic strategy but also as a factor impacting cancer progression, especially through platelet interactions.
Throughout our study, we discovered that calcium significantly affects the functionality of these integrins and the overall behavior of platelets. When we reduced calcium levels, we noticed a change in how platelets interacted with breast cancer cells (specifically MDA-MB-231). On the contrary, environments with high calcium levels did not seem to affect these interactions as significantly.
Interestingly, we observed that hypercalcemia, or elevated calcium levels, appeared to enhance cancer cell invasion in the presence of platelets for both breast and lung cancer cells (MDA-MB-231 and A549, respectively). This suggests that rather than obstructing metastatic processes, high calcium may facilitate cancer spread, offering a new perspective on calcium's role in cancer dynamics.
Overall, this study sheds light on how calcium adjustments could be viewed not only as a potential therapeutic strategy but also as a factor impacting cancer progression, especially through platelet interactions.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.7
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Significant improvement
I ordered this calcium for my sister when she had cancer, based on a doctor's recommendation. To be honest, it helped her immensely, and it works best when taken alongside omega 3.
9.5
Health improvement noted
I’ve been giving this calcium to my mother for three years and find it excellent. She had thyroid cancer, and due to hormone treatments and age, her calcium levels were depleting. The endocrinologist suggested this specific form. After reading reviews, we ordered it, and after a course of use, we noted significant improvements in her health. The drug's effect was remarkable, and her calcium deficiencies were resolved after six months.
Read More
