' 
SCIENTIFIC SCORE
Possibly Effective
Based on 21 Researches
7.6
USERS' SCORE
Good
Based on 3 Reviews
8.6
Supplement Facts
Serving Size: 2 Tablets
Amount Per Serving
%DV
Calcium (elemental) (from 2,775 mg complex of Calcium Carbonate, Calcium Citrate, Calcium Ascorbate)
1 g (1,000 mg)
77%
Magnesium (elemental) (from 928 mg complex of Magnesium Oxide, Magnesium Citrate, Magnesium Ascorbate)
500 mg
119%
Top Medical Research Studies
9
Magnesium intake linked to reduced hypertension
Associations between dietary magnesium intake and hypertension, diabetes, and hyperlipidemia.
High relevance for health concerns
We explored the connection between dietary magnesium intake and hypertension along with other health issues in US adults. In our study, we analyzed data from over 24,000 people, taking into account various lifestyle factors.
We found that those with higher magnesium intake had significantly lower rates of hypertension, diabetes, and hyperlipidemia compared to those with the least intake. Notably, participants in the highest quintile of magnesium consumption were less likely to suffer from these conditions.
These results suggest that increasing magnesium-rich foods in our diets could help prevent these prevalent health concerns.
We found that those with higher magnesium intake had significantly lower rates of hypertension, diabetes, and hyperlipidemia compared to those with the least intake. Notably, participants in the highest quintile of magnesium consumption were less likely to suffer from these conditions.
These results suggest that increasing magnesium-rich foods in our diets could help prevent these prevalent health concerns.
Read More
8
Magnesium effectively lowers blood pressure
Magnesium and Potassium Supplementation for Systolic Blood Pressure Reduction in the General Normotensive Population: A Systematic Review and Subgroup Meta-Analysis for Optimal Dosage and Treatment Length.
Focuses on magnesium's effects
We explored how magnesium supplementation can affect systolic blood pressure (SBP) in the general population. Through careful analysis of placebo-controlled, randomized clinical trials, we focused on understanding the optimal dosages and treatment durations necessary to achieve significant reductions in SBP. Past findings revealed that magnesium could reduce SBP by an average of 2.79 mm Hg, and our goal was to dive deeper into these results.
Our meta-analysis showed promising outcomes. Specifically, we noticed that magnesium taken at lower doses, particularly ≤360 mg per day, led to a notable decrease in SBP of about 3.03 mm Hg, especially when the treatment duration exceeded three months. This suggests that for those looking to manage their blood pressure, longer-term use of magnesium at these dosages may be beneficial.
While we found encouraging evidence pointing to the effectiveness of magnesium in lowering SBP, we acknowledge the importance of further studies. These future investigations should focus on varied dosages and longer follow-up periods to strengthen our understanding and provide tailored recommendations for individuals seeking to utilize magnesium in their hypertension management strategies.
Our meta-analysis showed promising outcomes. Specifically, we noticed that magnesium taken at lower doses, particularly ≤360 mg per day, led to a notable decrease in SBP of about 3.03 mm Hg, especially when the treatment duration exceeded three months. This suggests that for those looking to manage their blood pressure, longer-term use of magnesium at these dosages may be beneficial.
While we found encouraging evidence pointing to the effectiveness of magnesium in lowering SBP, we acknowledge the importance of further studies. These future investigations should focus on varied dosages and longer follow-up periods to strengthen our understanding and provide tailored recommendations for individuals seeking to utilize magnesium in their hypertension management strategies.
Read More
9.5
Clevidipine effectively manages hypertension
Clevidipine for hypertension treatment during laparoscopic adrenalectomy for pheochromocytoma in a dog.
Moderate relevance to calcium treatment
We observed the use of clevidipine, a calcium channel blocker, to manage hypertension in a dog undergoing surgery for pheochromocytoma. This treatment was initiated after the dog had been already prepared for surgery with medications like phenoxybenzamine, which was given to help control the underlying condition.
During the surgical procedure, when blood pressure spiked significantly due to adrenal gland manipulation, clevidipine was administered intravenously to help bring the mean arterial pressure down to a safer range. This swift action allowed the dog’s blood pressure and heart rate to stabilize, showcasing how effective clevidipine can be in these stressful situations.
After a successful surgery and recovery, the dog was discharged and showed stable clinical signs for two years afterward. Our findings highlight clevidipine's effectiveness as a fast-acting vasodilator with a strong safety profile, particularly in emergencies involving high blood pressure.
During the surgical procedure, when blood pressure spiked significantly due to adrenal gland manipulation, clevidipine was administered intravenously to help bring the mean arterial pressure down to a safer range. This swift action allowed the dog’s blood pressure and heart rate to stabilize, showcasing how effective clevidipine can be in these stressful situations.
After a successful surgery and recovery, the dog was discharged and showed stable clinical signs for two years afterward. Our findings highlight clevidipine's effectiveness as a fast-acting vasodilator with a strong safety profile, particularly in emergencies involving high blood pressure.
Read More
Most Useful Reviews
9.5
Reduced headaches
I am very satisfied with this product, and I've even ordered it for my mum as a supplement for her hypertension! Since she started, her headaches have noticeably decreased!
Read More
8.8
Heart protection
These are excellent vitamins for my mother, who suffers from hypertension. I purchased them to accompany her calcium and magnesium, aimed at protecting her heart. I completed my own course as well, ensuring we both benefit from these valuable supplements!
Read More
8
Improved mood
Magnesium is essential for converting food into energy, synthesising DNA and proteins, and conducting nerve impulses. It aids in maintaining a steady heartbeat, muscle contractions, and strong bones. A deficiency can increase the risk of cardiovascular diseases, hypertension, osteoporosis, and even type 2 diabetes. Calcium and Magnesium NOW Foods delivers 119% of the daily value of magnesium and 77% of calcium. I take 2 capsules during breakfast, along with vitamin D and krill oil. I find the taste neutral, as I drink it down with plenty of water. After two months of supplementation, my stress levels decreased and my mood has improved. Overall, I’m pleased and plan to take another course after a break!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 21 Researches
7.6
- All Researches
9.5
Clevidipine effectively manages hypertension
Clevidipine for hypertension treatment during laparoscopic adrenalectomy for pheochromocytoma in a dog.
Moderate relevance to calcium treatment
We observed the use of clevidipine, a calcium channel blocker, to manage hypertension in a dog undergoing surgery for pheochromocytoma. This treatment was initiated after the dog had been already prepared for surgery with medications like phenoxybenzamine, which was given to help control the underlying condition.
During the surgical procedure, when blood pressure spiked significantly due to adrenal gland manipulation, clevidipine was administered intravenously to help bring the mean arterial pressure down to a safer range. This swift action allowed the dog’s blood pressure and heart rate to stabilize, showcasing how effective clevidipine can be in these stressful situations.
After a successful surgery and recovery, the dog was discharged and showed stable clinical signs for two years afterward. Our findings highlight clevidipine's effectiveness as a fast-acting vasodilator with a strong safety profile, particularly in emergencies involving high blood pressure.
During the surgical procedure, when blood pressure spiked significantly due to adrenal gland manipulation, clevidipine was administered intravenously to help bring the mean arterial pressure down to a safer range. This swift action allowed the dog’s blood pressure and heart rate to stabilize, showcasing how effective clevidipine can be in these stressful situations.
After a successful surgery and recovery, the dog was discharged and showed stable clinical signs for two years afterward. Our findings highlight clevidipine's effectiveness as a fast-acting vasodilator with a strong safety profile, particularly in emergencies involving high blood pressure.
Read More
9
Magnesium improves pregnancy hypertension
Effects of magnesium sulfate combined with labetalol on vascular endothelial function and pregnancy outcomes in pregnant women with preeclampsia.
Combination treatment effectively evaluated
We conducted a retrospective study to investigate how magnesium sulfate paired with labetalol affects vascular health and pregnancy outcomes in women with preeclampsia—a serious condition that can occur during pregnancy characterized by high blood pressure.
Our analysis focused on clinical data from 262 women treated for preeclampsia. The patients were divided into two groups: one group received magnesium sulfate alone, while the other group was treated with both magnesium sulfate and labetalol. By measuring key indicators such as nitric oxide and endothelin-1 levels, along with blood pressure readings, we aimed to determine the effectiveness of these treatments.
The results showed that the combination of magnesium sulfate and labetalol notably improved vascular function and pregnancy outcomes for these women. Not only did this treatment help in better controlling high blood pressure during pregnancy, but it also reduced the chances of adverse outcomes for both mothers and babies. Importantly, the study found this combined treatment to be as safe as using magnesium sulfate alone.
This reinforces the idea that magnesium can play a significant role in treating hypertension during pregnancy, especially when paired with other medications like labetalol.
Our analysis focused on clinical data from 262 women treated for preeclampsia. The patients were divided into two groups: one group received magnesium sulfate alone, while the other group was treated with both magnesium sulfate and labetalol. By measuring key indicators such as nitric oxide and endothelin-1 levels, along with blood pressure readings, we aimed to determine the effectiveness of these treatments.
The results showed that the combination of magnesium sulfate and labetalol notably improved vascular function and pregnancy outcomes for these women. Not only did this treatment help in better controlling high blood pressure during pregnancy, but it also reduced the chances of adverse outcomes for both mothers and babies. Importantly, the study found this combined treatment to be as safe as using magnesium sulfate alone.
This reinforces the idea that magnesium can play a significant role in treating hypertension during pregnancy, especially when paired with other medications like labetalol.
Read More
9
Magnesium's effects on PAH treatment
Monocrotaline-induced pulmonary arterial hypertension: the benefic effects of magnesium sulfate, Rosuvastatin and Sildenafil.
Combination treatment limits isolation
We examined an experimental model of pulmonary arterial hypertension (PAH) induced by monocrotaline in rats. Our research focused on the combined effects of Magnesium sulfate along with Rosuvastatin and Sildenafil, which were administered two weeks after the initial MCT injection.
Using measures like the Fulton Index and various cardiac dimensions, we observed improvements in right ventricular function and markers of oxidative stress. Notably, Magnesium sulfate appeared to work well with Rosuvastatin, which is known for its anti-inflammatory properties, enhancing the overall treatment effectiveness on pulmonary hypertension.
However, since Magnesium was administered in combination with these other treatments, we could not determine its isolated benefits on hypertension specifically. The study did highlight the importance of multi-pronged approaches in tackling such complex conditions, suggesting that further research might clarify Magnesium's unique contributions to managing hypertension.
Using measures like the Fulton Index and various cardiac dimensions, we observed improvements in right ventricular function and markers of oxidative stress. Notably, Magnesium sulfate appeared to work well with Rosuvastatin, which is known for its anti-inflammatory properties, enhancing the overall treatment effectiveness on pulmonary hypertension.
However, since Magnesium was administered in combination with these other treatments, we could not determine its isolated benefits on hypertension specifically. The study did highlight the importance of multi-pronged approaches in tackling such complex conditions, suggesting that further research might clarify Magnesium's unique contributions to managing hypertension.
Read More
9
Magnesium sulfate reduces neonatal brain injury
Magnesium sulfate and risk of hypoxic-ischemic encephalopathy in a high-risk cohort.
Relevant findings for perinatal care.
We examined a cohort of neonates born at or above 36 weeks gestation to assess the impact of antenatal magnesium sulfate on hypoxic-ischemic encephalopathy linked to hypertensive disorders of pregnancy.
Our analysis revealed that these disorders significantly increase the risk of moderate to severe brain injury. Importantly, we observed that receiving magnesium sulfate reduced the odds of developing hypoxic-ischemic encephalopathy in affected infants.
However, it’s crucial to understand that while our study shows an association, it does not establish a cause-and-effect relationship.
Our analysis revealed that these disorders significantly increase the risk of moderate to severe brain injury. Importantly, we observed that receiving magnesium sulfate reduced the odds of developing hypoxic-ischemic encephalopathy in affected infants.
However, it’s crucial to understand that while our study shows an association, it does not establish a cause-and-effect relationship.
Read More
9
Magnesium intake linked to reduced hypertension
Associations between dietary magnesium intake and hypertension, diabetes, and hyperlipidemia.
High relevance for health concerns
We explored the connection between dietary magnesium intake and hypertension along with other health issues in US adults. In our study, we analyzed data from over 24,000 people, taking into account various lifestyle factors.
We found that those with higher magnesium intake had significantly lower rates of hypertension, diabetes, and hyperlipidemia compared to those with the least intake. Notably, participants in the highest quintile of magnesium consumption were less likely to suffer from these conditions.
These results suggest that increasing magnesium-rich foods in our diets could help prevent these prevalent health concerns.
We found that those with higher magnesium intake had significantly lower rates of hypertension, diabetes, and hyperlipidemia compared to those with the least intake. Notably, participants in the highest quintile of magnesium consumption were less likely to suffer from these conditions.
These results suggest that increasing magnesium-rich foods in our diets could help prevent these prevalent health concerns.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Reduced headaches
I am very satisfied with this product, and I've even ordered it for my mum as a supplement for her hypertension! Since she started, her headaches have noticeably decreased!
8.8
Heart protection
These are excellent vitamins for my mother, who suffers from hypertension. I purchased them to accompany her calcium and magnesium, aimed at protecting her heart. I completed my own course as well, ensuring we both benefit from these valuable supplements!
8
Improved mood
Magnesium is essential for converting food into energy, synthesising DNA and proteins, and conducting nerve impulses. It aids in maintaining a steady heartbeat, muscle contractions, and strong bones. A deficiency can increase the risk of cardiovascular diseases, hypertension, osteoporosis, and even type 2 diabetes. Calcium and Magnesium NOW Foods delivers 119% of the daily value of magnesium and 77% of calcium. I take 2 capsules during breakfast, along with vitamin D and krill oil. I find the taste neutral, as I drink it down with plenty of water. After two months of supplementation, my stress levels decreased and my mood has improved. Overall, I’m pleased and plan to take another course after a break!
Read More
