Can NOW Supplements Inulin Prebiotic Powder Help with Anxiety?
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.7
USERS' SCORE
Good
Based on 3 Reviews
8
Supplement Facts
Serving Size: 1 Level Teaspoon (approx. 4 g)
Amount Per Serving
%DV
Calories
10
Total Carbohydrate
4 g
1%**
Dietary Fiber
4 g
14%*
Organic Inulin (FOS) (from Blue Agave)
3.3 g
†
Top Medical Research Studies
9.5
Inulin reduces anxiety in migraines
A randomized, double-blind, placebo-controlled parallel trial to test the effect of inulin supplementation on migraine headache characteristics, quality of life and mental health symptoms in women with migraine.
We conducted a fascinating study to understand how inulin supplementation might affect anxiety levels in women suffering from migraines. By design, this was a randomized, double-blind, placebo-controlled trial involving 80 women aged 20 to 50 years old. Participants received either 10 grams of inulin daily or a placebo for 12 weeks.
Our results showed promising findings regarding anxiety. Specifically, we observed a significant decrease in anxiety levels among those taking inulin, with a reduction of 4.37 points compared to the placebo group. This indicates that inulin may play a role in enhancing mental well-being in those experiencing migraine headaches.
It's worth noting that while we found improvements in anxiety and other mental health symptoms such as stress and depression, the quality of life scores did not show a significant difference between the two groups. This could suggest that while inulin helps with anxiety, it might not immediately influence overall quality of life in women with migraines.
Such findings are encouraging and suggest that inulin supplementation can provide a natural avenue to alleviate some mental health challenges associated with migraine episodes. We believe further research could shed more light on these effects.
Read More
8
Inulin's timing impacts anxiety relief
Administration time modify the anxiolytic and antidepressant effects of inulin via gut-brain axis.
We investigated how inulin, a type of dietary fiber, can influence anxiety and depression, particularly through its interaction with the gut-brain axis. Our research showed that the timing of inulin consumption significantly affects its ability to alleviate anxiety and depression-like behaviors induced by chronic unpredictable mild stress (CUMS).
Through fecal microbiota transplantation, we confirmed that when inulin is taken at different times, it produces varying effects on anxiety levels. Notably, administering inulin in the evening had a more pronounced impact on reducing inflammation compared to taking it in the morning.
Moreover, metabolomic analysis revealed that certain metabolites, such as fenofibric acid and 4'-Hydroxyfenoprofen glucuronide, could play crucial roles in these effects. Overall, our findings suggest that evening inulin consumption not only improves inflammation but also enhances amino acid metabolism, highlighting the importance of timing in nutritional interventions for anxiety relief.
Read More
8
Inulin improves anxiety in withdrawal
Prebiotic inulin alleviates anxiety and depression-like behavior in alcohol withdrawal mice by modulating the gut microbiota and 5-HT metabolism.
To understand how inulin, a prebiotic, affects anxiety, we investigated its potential benefits in mice undergoing alcohol withdrawal. We created a model of alcohol dependence and treated the mice with inulin, while also using fluvoxamine maleate—a common antidepressant—as a comparison. Over the course of four weeks, we monitored how the mice behaved in tests designed to measure anxiety and depression-like symptoms.
Our findings were promising. Mice treated with inulin showed significant improvements in anxiety-related behaviors. We observed notable changes in their gut microbiota and serotonin (5-HT) metabolism, which are often disrupted in individuals with alcohol dependence. Inulin increased the presence of beneficial bacteria like Faecalibacterium and Roseburia and enhanced the production of short-chain fatty acids (SCFAs), which play a crucial role in gut health.
These results suggest that inulin can offer a nutritional intervention for individuals suffering from anxiety and depression, particularly in the context of alcohol withdrawal. By influencing the delicate balance of gut microbiota and serotonin levels, inulin may help support mental health during recovery from alcohol dependence.
Read More
Most Useful Reviews
9
Brain clarity regained
9 people found this helpful
There is a noticeable result! I had colon issues and began taking a teaspoon of inulin each day with green tea, which was delightful—like childhood toffee. I soon increased it to two teaspoons, and the entire jar was gone within weeks. The effects were almost immediate: my stool improved, and bloating and flatulence vanished. As a bonus, my mental clarity improved, and my anxiety diminished. My mood has brightened significantly! I will certainly purchase more.
Read More
6
Stomach improved
144 people found this helpful
I was having issues with my gastrointestinal tract, which led to various problems like indigestion and irregular stools. My doctor recommended inulin to help normalise my gut function. After a few days of taking it alongside probiotics, my stools became regular, bloating subsided, and my stomach anxiety lessened after eating. Prior to this treatment, my stomach would react poorly post-meal. Now, I take inulin with probiotics about once every six months, and I no longer face these issues. Occasionally, I use it after feasts to prevent discomfort from heavy meals, taking it for a week.
Read More
7.5
Anxiety relieved
Excellent! This product offers great calming effects and effectively relieves anxiety. It serves as a substitute for the pharmacy equivalent at a much more advantageous price. I take two capsules daily.
A randomized, double-blind, placebo-controlled parallel trial to test the effect of inulin supplementation on migraine headache characteristics, quality of life and mental health symptoms in women with migraine.
We conducted a fascinating study to understand how inulin supplementation might affect anxiety levels in women suffering from migraines. By design, this was a randomized, double-blind, placebo-controlled trial involving 80 women aged 20 to 50 years old. Participants received either 10 grams of inulin daily or a placebo for 12 weeks.
Our results showed promising findings regarding anxiety. Specifically, we observed a significant decrease in anxiety levels among those taking inulin, with a reduction of 4.37 points compared to the placebo group. This indicates that inulin may play a role in enhancing mental well-being in those experiencing migraine headaches.
It's worth noting that while we found improvements in anxiety and other mental health symptoms such as stress and depression, the quality of life scores did not show a significant difference between the two groups. This could suggest that while inulin helps with anxiety, it might not immediately influence overall quality of life in women with migraines.
Such findings are encouraging and suggest that inulin supplementation can provide a natural avenue to alleviate some mental health challenges associated with migraine episodes. We believe further research could shed more light on these effects.
Read More
9
Inulin reduces anxiety in stressed mice
The Influence of Topinambur and Inulin Preventive Supplementation on Microbiota, Anxious Behavior, Cognitive Functions and Neurogenesis in Mice Exposed to the Chronic Unpredictable Mild Stress.
We explored the impact of inulin supplementation on anxiety levels in mice subjected to chronic unpredictable mild stress (CUMS). The study looked at how natural prebiotics, such as topinambur powder and chicory root inulin, influence anxiety and cognitive functions.
Over a period of 10 weeks, we administered inulin alongside topinambur to observe any changes in behavior and neurogenesis compared to a control group. Excitingly, we found that both inulin and topinambur, just like fluoxetine—a known antidepressant—significantly reduced anxiety and depression-like behaviors.
Furthermore, we noted improvements in learning and memory skills for the mice receiving these supplements. Fecal microbiota analysis also revealed that inulin played a role in counteracting stress-induced intestinal disruptions, making it a potentially valuable addition to diets for improving mental health under stress.
Overall, our findings suggest that inulin not only helps mitigate anxiety but also supports cognitive functions during stressful conditions in mice. This shines a light on the potential benefits of prebiotics for mental health.
Read More
8
Inulin's timing impacts anxiety relief
Administration time modify the anxiolytic and antidepressant effects of inulin via gut-brain axis.
We investigated how inulin, a type of dietary fiber, can influence anxiety and depression, particularly through its interaction with the gut-brain axis. Our research showed that the timing of inulin consumption significantly affects its ability to alleviate anxiety and depression-like behaviors induced by chronic unpredictable mild stress (CUMS).
Through fecal microbiota transplantation, we confirmed that when inulin is taken at different times, it produces varying effects on anxiety levels. Notably, administering inulin in the evening had a more pronounced impact on reducing inflammation compared to taking it in the morning.
Moreover, metabolomic analysis revealed that certain metabolites, such as fenofibric acid and 4'-Hydroxyfenoprofen glucuronide, could play crucial roles in these effects. Overall, our findings suggest that evening inulin consumption not only improves inflammation but also enhances amino acid metabolism, highlighting the importance of timing in nutritional interventions for anxiety relief.
Read More
8
Inulin improves anxiety in withdrawal
Prebiotic inulin alleviates anxiety and depression-like behavior in alcohol withdrawal mice by modulating the gut microbiota and 5-HT metabolism.
To understand how inulin, a prebiotic, affects anxiety, we investigated its potential benefits in mice undergoing alcohol withdrawal. We created a model of alcohol dependence and treated the mice with inulin, while also using fluvoxamine maleate—a common antidepressant—as a comparison. Over the course of four weeks, we monitored how the mice behaved in tests designed to measure anxiety and depression-like symptoms.
Our findings were promising. Mice treated with inulin showed significant improvements in anxiety-related behaviors. We observed notable changes in their gut microbiota and serotonin (5-HT) metabolism, which are often disrupted in individuals with alcohol dependence. Inulin increased the presence of beneficial bacteria like Faecalibacterium and Roseburia and enhanced the production of short-chain fatty acids (SCFAs), which play a crucial role in gut health.
These results suggest that inulin can offer a nutritional intervention for individuals suffering from anxiety and depression, particularly in the context of alcohol withdrawal. By influencing the delicate balance of gut microbiota and serotonin levels, inulin may help support mental health during recovery from alcohol dependence.
Read More
8
Oligofructose improves mood states
Inulin-type fructans and 2'fucosyllactose alter both microbial composition and appear to alleviate stress-induced mood state in a working population compared to placebo (maltodextrin): the EFFICAD Trial, a randomized, controlled trial.
In a recent study, we investigated the effects of a specific type of dietary fiber known as oligofructose and a compound called 2'fucosyllactose on anxiety and mood in a group of working adults. This was a well-designed trial, where 92 healthy participants dealing with mild to moderate anxiety were randomly assigned to receive different treatments over five weeks.
Participants were placed into four groups: some received oligofructose alone, others got 2'fucosyllactose, while a third group received a combination of both, and a control group took maltodextrin, which served as a placebo. We looked closely at how these treatments influenced not only the gut microbiome, which is known to play a role in mental health, but also the participants' mood states.
The findings were promising; we observed that both oligofructose and the combination with 2'fucosyllactose positively altered microbial composition. More importantly, these changes were associated with improvements in mood state among the participants. While more research is needed, especially to identify individual responses to 2'fucosyllactose, these results suggest that dietary interventions involving inulin-type fructans can be beneficial in managing anxiety.
There is a noticeable result! I had colon issues and began taking a teaspoon of inulin each day with green tea, which was delightful—like childhood toffee. I soon increased it to two teaspoons, and the entire jar was gone within weeks. The effects were almost immediate: my stool improved, and bloating and flatulence vanished. As a bonus, my mental clarity improved, and my anxiety diminished. My mood has brightened significantly! I will certainly purchase more.
Read More
6
Stomach improved
144 people found this helpful
I was having issues with my gastrointestinal tract, which led to various problems like indigestion and irregular stools. My doctor recommended inulin to help normalise my gut function. After a few days of taking it alongside probiotics, my stools became regular, bloating subsided, and my stomach anxiety lessened after eating. Prior to this treatment, my stomach would react poorly post-meal. Now, I take inulin with probiotics about once every six months, and I no longer face these issues. Occasionally, I use it after feasts to prevent discomfort from heavy meals, taking it for a week.
Read More
7.5
Anxiety relieved
Excellent! This product offers great calming effects and effectively relieves anxiety. It serves as a substitute for the pharmacy equivalent at a much more advantageous price. I take two capsules daily.
Read More
Frequently Asked Questions
Anxiety is a natural and often healthy emotion characterized by feelings of worry, nervousness, or fear about an impending event or situation. While some level of anxiety is a normal reaction to stress, excessive or chronic anxiety can become a mental health issue. It may present in various forms, from everyday worries to more severe conditions such as generalized anxiety disorder (GAD), panic disorder, or social anxiety disorder. Symptoms can manifest both psychologically, such as persistent worry and difficulty concentrating, and physically, including symptoms like increased heart rate, sweating, or fatigue.
Understanding the difference between normal anxiety and an anxiety disorder is crucial. Normal anxiety can be beneficial, motivating you to prepare for important events like exams or public speaking. However, when it starts to interfere with daily activities or leads to avoidance behaviors, it may indicate the need for professional help. Treatments for anxiety often include therapy, medications, and lifestyle changes, allowing individuals to manage their symptoms effectively. If someone is struggling with anxiety that impacts their quality of life, seeking guidance from a healthcare professional is a key step toward recovery.
Prebiotic fiber inulin is a naturally occurring carbohydrate found in a variety of plants, particularly in roots and tubers such as chicory, garlic, leeks, and onions. As a soluble fiber, it is not digested in the small intestine but rather fermented by beneficial gut bacteria in the large intestine. This fermentation process helps promote the growth of beneficial bacteria, which can support gut health, improve digestion, and enhance the absorption of certain nutrients. Increasing dietary intake of prebiotic fibers like inulin can contribute to a healthier microbiome.
In addition to its benefits for gut health, inulin can also help to enhance feelings of fullness and reduce appetite, making it a popular ingredient in weight management products. It is often added to food and beverage items as a texturizer or sweetener because it offers a mildly sweet flavor without contributing significant calories. Given its numerous health benefits, inulin is frequently emphasized in discussions about dietary fiber and overall nutrition, making it a valuable component of a balanced diet.
Based on user reviews, results from taking this supplement for anxiety can vary, but many users report experiencing noticeable improvements relatively quickly. For instance, one user mentioned that within just a few days of integrating the supplement into their routine, they noticed a significant reduction in anxiety alongside other gastrointestinal benefits (Read Review). Similarly, another user highlighted the calming effects and relief from anxiety as they incorporated the product into their daily regimen, suggesting that some users may feel the benefits in a short period (Read Review).
Overall, while individual results may differ, it's common for users to experience improvements within days to weeks of consistent use. This aligns with anecdotal evidence indicating that the supplement not only helps with gastrointestinal discomfort but also enhances mental clarity and mood, leading to a holistic sense of well-being. Therefore, if you’re considering this supplement for anxiety relief, you may want to monitor your progress over the course of the first few weeks to gauge its effectiveness for you.
Recent research highlights that inulin, a type of prebiotic dietary fiber, may offer significant benefits for individuals experiencing anxiety. Studies have demonstrated that inulin can positively influence anxiety levels through mechanisms related to gut health and microbial composition. For instance, one study showed that mice undergoing alcohol withdrawal exhibited notable improvements in anxiety-related behaviors after inulin administration, suggesting its potential role in alleviating anxiety during stressful circumstances [2]. Another randomized trial involving women with migraines reported a significant decrease in anxiety levels among participants who consumed inulin over 12 weeks, underscoring its promise as a natural supplemental option for mental well-being [3].
Furthermore, investigations into the combined effects of inulin with probiotics found that such co-supplementation can lead to significant improvements in anxiety levels among individuals dealing with chronic health issues [7]. These encouraging results position inulin as a potential adjunctive strategy in managing anxiety, particularly in specific populations experiencing related stressors. While more extensive studies are warranted to fully ascertain its long-term impacts, current findings advocate for inulin’s inclusion in dietary interventions aimed at supporting mental health.
Based on user reviews, there are several reported improvements in symptoms related to gastrointestinal issues and anxiety after starting inulin. For instance, one user noted almost immediate results, including improved stool consistency, a significant reduction in bloating and flatulence, and an overall enhancement in mental clarity and mood following the intake of inulin (Read Review). Another reviewer emphasized the normalization of gut function after a few days of using inulin alongside probiotics, which alleviated their digestive issues and helped reduce anxiety associated with eating (Read Review).
Additionally, some users have experienced great calming effects and effective anxiety relief from the product, indicating that it serves as a beneficial alternative to more conventional treatments (Read Review). While these anecdotal experiences highlight significant improvements for many, it’s important to remember that individual results can vary widely, and what works for one person may not have the same effect for another.
Users have reported positive experiences when combining this supplement with other products for managing anxiety, particularly with probiotics. One reviewer noted that after taking inulin alongside probiotics for several days, not only did their digestive issues improve, but they also experienced a noticeable reduction in anxiety related to eating (Read Review). Another user emphasized the calming effects of this supplement, indicating that it serves as an effective alternative to traditional anxiety treatments (Read Review).
These experiences suggest that users find a synergistic effect when combining inulin with probiotics, as the combination appears to alleviate gastrointestinal discomfort while concurrently diminishing anxiety levels. This dual benefit highlights the potential for enhanced mental well-being, making it a noteworthy consideration for those looking to handle anxiety more effectively through dietary supplements.
Users report positive effects on anxiety when incorporating Prebiotic Fiber Inulin into their daily routine, suggesting a dose range of one to two teaspoons per day. For instance, one user noted significant improvements in mood and anxiety after increasing their intake from one teaspoon to two teaspoons mixed with green tea, which they found delightful, ultimately leading to a brightened mood and diminished anxiety symptoms Read Review. Another user complemented their experience by combining inulin with probiotics, observing a decrease in stomach anxiety after meals, indicating that integrating both into their regimen helped maintain a more stable gut function and reduced anxiety Read Review.
Overall, while specific dosages may vary among individuals, the general consensus suggests that doses around one to two teaspoons daily could be beneficial for those seeking to alleviate anxiety symptoms through gut health improvement. Moreover, one review highlights taking two capsules daily, which points to flexibility in how consumers can integrate inulin into their routines Read Review. As with all supplements, it is advisable to consult with a healthcare professional before starting any new regimen.
6
Stomach improved
144 people found this helpful
I was having issues with my gastrointestinal tract, which led to various problems like indigestion and irregular stools. My doctor recommended inulin to help normalise my gut function. After a few days of taking it alongside probiotics, my stools became regular, bloating subsided, and my stomach anxiety lessened after eating. Prior to this treatment, my stomach would react poorly post-meal. Now, I take inulin with probiotics about once every six months, and I no longer face these issues. Occasionally, I use it after feasts to prevent discomfort from heavy meals, taking it for a week.
7.5
Anxiety relieved
Excellent! This product offers great calming effects and effectively relieves anxiety. It serves as a substitute for the pharmacy equivalent at a much more advantageous price. I take two capsules daily.
9
Brain clarity regained
9 people found this helpful
There is a noticeable result! I had colon issues and began taking a teaspoon of inulin each day with green tea, which was delightful—like childhood toffee. I soon increased it to two teaspoons, and the entire jar was gone within weeks. The effects were almost immediate: my stool improved, and bloating and flatulence vanished. As a bonus, my mental clarity improved, and my anxiety diminished. My mood has brightened significantly! I will certainly purchase more.
8
Inulin improves anxiety in withdrawal
Prebiotic inulin alleviates anxiety and depression-like behavior in alcohol withdrawal mice by modulating the gut microbiota and 5-HT metabolism.
To understand how inulin, a prebiotic, affects anxiety, we investigated its potential benefits in mice undergoing alcohol withdrawal. We created a model of alcohol dependence and treated the mice with inulin, while also using fluvoxamine maleate—a common antidepressant—as a comparison. Over the course of four weeks, we monitored how the mice behaved in tests designed to measure anxiety and depression-like symptoms.
Our findings were promising. Mice treated with inulin showed significant improvements in anxiety-related behaviors. We observed notable changes in their gut microbiota and serotonin (5-HT) metabolism, which are often disrupted in individuals with alcohol dependence. Inulin increased the presence of beneficial bacteria like Faecalibacterium and Roseburia and enhanced the production of short-chain fatty acids (SCFAs), which play a crucial role in gut health.
These results suggest that inulin can offer a nutritional intervention for individuals suffering from anxiety and depression, particularly in the context of alcohol withdrawal. By influencing the delicate balance of gut microbiota and serotonin levels, inulin may help support mental health during recovery from alcohol dependence.
9.5
Inulin reduces anxiety in migraines
A randomized, double-blind, placebo-controlled parallel trial to test the effect of inulin supplementation on migraine headache characteristics, quality of life and mental health symptoms in women with migraine.
We conducted a fascinating study to understand how inulin supplementation might affect anxiety levels in women suffering from migraines. By design, this was a randomized, double-blind, placebo-controlled trial involving 80 women aged 20 to 50 years old. Participants received either 10 grams of inulin daily or a placebo for 12 weeks.
Our results showed promising findings regarding anxiety. Specifically, we observed a significant decrease in anxiety levels among those taking inulin, with a reduction of 4.37 points compared to the placebo group. This indicates that inulin may play a role in enhancing mental well-being in those experiencing migraine headaches.
It's worth noting that while we found improvements in anxiety and other mental health symptoms such as stress and depression, the quality of life scores did not show a significant difference between the two groups. This could suggest that while inulin helps with anxiety, it might not immediately influence overall quality of life in women with migraines.
Such findings are encouraging and suggest that inulin supplementation can provide a natural avenue to alleviate some mental health challenges associated with migraine episodes. We believe further research could shed more light on these effects.
8
Inulin improves anxiety in CAD
The effects of co-administration of probiotics and prebiotics on chronic inflammation, and depression symptoms in patients with coronary artery diseases: a randomized clinical trial.
We explored the potential benefits of combining probiotics and inulin on anxiety levels in patients with coronary artery disease (CAD). In a well-structured study, 96 participants were randomly divided into four groups—one receiving only the probiotic strain, another taking inulin, a third group receiving both, and a fourth group as a placebo. They consumed these supplements for two months while their anxiety and depression levels were regularly assessed.
Our findings revealed that co-supplementation, particularly combining inulin with the probiotic, led to significant improvements in anxiety levels and overall well-being. This combination appeared to provide greater benefits than taking either supplement alone, showing promise for managing psychological symptoms linked to chronic conditions like CAD. However, since all the investigated participants were under chronic stress due to their health issues, we should remain cautious and consider more extensive studies to confirm these positive results for a broader population.
Overall, it looks like inulin, especially when paired with probiotics, contributes positively to reducing anxiety among CAD patients, which could ultimately enhance their quality of life.
References
Chen P, Chen F, Hou T, Hu X, Xia C, et al. Administration time modify the anxiolytic and antidepressant effects of inulin via gut-brain axis. Int J Biol Macromol. 2025;288:138698. doi:10.1016/j.ijbiomac.2024.138698
Li K, Wei W, Xu C, Lian X, Bao J, et al. Prebiotic inulin alleviates anxiety and depression-like behavior in alcohol withdrawal mice by modulating the gut microbiota and 5-HT metabolism. Phytomedicine. 2024;135:156181. doi:10.1016/j.phymed.2024.156181
Vajdi M, Khorvash F, Askari G. A randomized, double-blind, placebo-controlled parallel trial to test the effect of inulin supplementation on migraine headache characteristics, quality of life and mental health symptoms in women with migraine. Food Funct. 2024;15:10088. doi:10.1039/d4fo02796e
Jackson PP, Wijeyesekera A, Williams CM, Theis S, van Harsselaar J, et al. Inulin-type fructans and 2'fucosyllactose alter both microbial composition and appear to alleviate stress-induced mood state in a working population compared to placebo (maltodextrin): the EFFICAD Trial, a randomized, controlled trial. Am J Clin Nutr. 2023;118:938. doi:10.1016/j.ajcnut.2023.08.016
Szala-Rycaj J, Szewczyk A, Zagaja M, Kaczmarczyk-Ziemba A, Maj M, et al. The Influence of Topinambur and Inulin Preventive Supplementation on Microbiota, Anxious Behavior, Cognitive Functions and Neurogenesis in Mice Exposed to the Chronic Unpredictable Mild Stress. Nutrients. 2023;15. doi:10.3390/nu15092041
Amadieu C, Coste V, Neyrinck AM, Thijssen V, Leyrolle Q, et al. Restoring an adequate dietary fiber intake by inulin supplementation: a pilot study showing an impact on gut microbiota and sociability in alcohol use disorder patients. Gut Microbes. 2022;14:2007042. doi:10.1080/19490976.2021.2007042
Moludi J, Khedmatgozar H, Nachvak SM, Abdollahzad H, Moradinazar M, et al. The effects of co-administration of probiotics and prebiotics on chronic inflammation, and depression symptoms in patients with coronary artery diseases: a randomized clinical trial. Nutr Neurosci. 2022;25:1659. doi:10.1080/1028415X.2021.1889451
Guo L, Xiao P, Zhang X, Yang Y, Yang M, et al. Inulin ameliorates schizophrenia modulation of the gut microbiota and anti-inflammation in mice. Food Funct. 2021;12:1156. doi:10.1039/d0fo02778b
Morshedi M, Valenlia KB, Hosseinifard ES, Shahabi P, Abbasi MM, et al. Beneficial psychological effects of novel psychobiotics in diabetic rats: the interaction among the gut, blood and amygdala. J Nutr Biochem. 2018;57:145. doi:10.1016/j.jnutbio.2018.03.022
Barrera-Bugueño C, Realini O, Escobar-Luna J, Sotomayor-Zárate R, Gotteland M, et al. Anxiogenic effects of a Lactobacillus, inulin and the synbiotic on healthy juvenile rats. Neuroscience. 2017;359:18. doi:10.1016/j.neuroscience.2017.06.064