'
NOW Supplements Melatonin
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.9
USERS' SCORE
Good
Based on 2 Reviews
8.5
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Green Tea Extract (Camellia sinensis) (Leaf) [350 mg EGCg (Epigallocatechin Gallate)] (up to 7 mg of naturally occurring caffeine)
700 mg
*

Top Medical Research Studies

9
Green tea mitigates BPA anxiety
Green Tea Diet Can Effectively Antagonize the Toxicity Induced by Environmental-Related Concentrations of BPA: An Implication from and Studies.
Directly addresses BPA anxiety
We set out to explore how green tea affects anxiety, particularly in the context of exposure to bisphenol A (BPA), a chemical known for its neurotoxic effects. To conduct this investigation, mice were exposed to different concentrations of BPA and given complimentary green tea starting at a specific developmental stage.

After the treatment period, we observed the mice’s behavior through various tests designed to measure anxiety levels and memory capabilities. Strikingly, the results revealed that the green tea diet significantly reduced anxiety-like behaviors that had been triggered by BPA.

On a deeper level, we uncovered that green tea helped to reverse harmful changes in the brain, including the activation of microglia, which are immune cells in the brain often linked to neuroinflammation. The green tea diet also appeared to suppress several markers of neuroinflammation associated with BPA exposure.

Ultimately, our findings suggest that incorporating green tea into one’s diet may be a simple yet effective approach to mitigating anxiety disorders linked to environmental toxins like BPA. This study highlights the potential of natural remedies in combating modern-day chemical exposures.
Read More
9
Green tea nanoparticles ease anxiety
Green Tea Polyphenol Nanoparticles Reduce Anxiety Caused by Tobacco Smoking Withdrawal in Rats by Suppressing Neuroinflammation.
Highly relevant study findings
In our study, we aimed to understand how green tea, specifically its antioxidant-rich nanoparticles, might influence anxiety related to withdrawal from tobacco smoking. We conducted our experiment on rats that were exposed to tobacco smoke daily for several weeks. This exposure was known to induce anxiety-like behavior as part of the withdrawal process.

After 20 days of exposure, we administered green tea nanoparticles to half of the rats to see if this treatment could alleviate their anxiety levels. Our findings were promising; the rats that received the green tea nanoparticles showed reduced signs of anxiety compared to those that didn’t receive any treatment. We measured various factors in the rats’ brains, including markers of neuroinflammation and neuroplasticity, and found that the nanoparticles helped to regulate these responses.

Overall, this study suggests that green tea nanoparticles could play a protective role in managing tobacco withdrawal symptoms, particularly anxiety. We may have found a natural option to help ease the turmoil of quitting smoking.
Read More
9
EGCG reduces anxiety in withdrawal
Epigallocatechin Gallate Ameliorates Nicotine Withdrawal Conditions-Induced Somatic and Affective Behavior Changes in Mice and Its Molecular Mechanism.
Highly relevant to anxiety treatment
We explored how the green tea compound, epigallocatechin gallate (EGCG), affects anxiety and other behaviors during nicotine withdrawal (NW) in mice. Our study involved observing the behaviors of 24 male mice, divided into four groups, with one group receiving nicotine and another receiving EGCG after the withdrawal.

The results showed that mice experiencing nicotine withdrawal displayed increased food intake, body weight, and signs of anxiety, which highlights the struggles associated with quitting nicotine. However, when we introduced EGCG, the mice not only consumed less food and gained less weight but also showed a significant decrease in anxiety-like behaviors.

At a molecular level, we noted EGCG's positive effects on certain brain signals related to stress and appetite regulation. Specifically, it reduced the expression of corticotropin-releasing factor (CRF), which is associated with stress, while boosting pro-opiomelanocortin (POMC), a signaling molecule related to reducing anxiety and controlling appetite. It appears that EGCG can improve both somatic and emotional responses during nicotine withdrawal by balancing these signaling pathways in the brain.
Read More

Most Useful Reviews

8.3
Improves sleep quality
It works for me. I suffer from anxiety, which makes it difficult to fall asleep and stay asleep during stressful times. Without aid, my sleep varies greatly. OTC medications helped, but I was cautious about their long-term use. These Melatonin tablets have been effective; one tablet before bed generally suffices. Some reviews suggest it helps maintain good sleep rather than inducing it, but I find I feel notably more tired about half an hour after taking one, helping me to sleep. Overall, I’m genuinely impressed.
Read More
8.8
Beneficial for anxiety
I am impressed with NOW products. My son is autistic, and melatonin is essential for aiding his relaxation and sleep. I intend to purchase more NOW products for mood, anxiety, and sleep since their ingredients surpass those in store products. My son, who avoids prescription medication, appears to sleep better on this melatonin than with another brand. It's too early to be certain, but I believe the improved sleep is attributed to NOW melatonin.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.9
  • All Researches
9
Green tea nanoparticles reduce anxiety
Green tea silver nanoparticles improve physiological motor and cognitive function in mice during inflammation.
Moderate focus on anxiety outcomes
We explored the impact of green tea silver nanoparticles on anxiety and inflammation in male mice. The study involved injecting the mice with a substance to induce acute inflammation, followed by treatment with different concentrations of green tea extract. This approach allowed us to observe how varying doses affected not only inflammation but also anxiety-like behaviors in the animals.

Our findings revealed that higher concentrations of green tea silver nanoparticles significantly reduced anxiety levels in the mice. Specifically, the mice treated with the high concentration showed the least anxiety, which corresponded to increased locomotion and overall activity. It was interesting to see that while low concentrations also had an effect on inflammation, the most dramatic results, particularly concerning anxiety reduction, were evident with medium and high concentrations.

These results suggest that green tea nanoparticles not only help with inflammation but could also be beneficial for anxiety management. Thus, incorporating green tea extract into complementary therapies might be a valuable strategy for enhancing mental and physical well-being in situations of stress and inflammation.
Read More
9
Green tea mitigates BPA anxiety
Green Tea Diet Can Effectively Antagonize the Toxicity Induced by Environmental-Related Concentrations of BPA: An Implication from and Studies.
Directly addresses BPA anxiety
We set out to explore how green tea affects anxiety, particularly in the context of exposure to bisphenol A (BPA), a chemical known for its neurotoxic effects. To conduct this investigation, mice were exposed to different concentrations of BPA and given complimentary green tea starting at a specific developmental stage.

After the treatment period, we observed the mice’s behavior through various tests designed to measure anxiety levels and memory capabilities. Strikingly, the results revealed that the green tea diet significantly reduced anxiety-like behaviors that had been triggered by BPA.

On a deeper level, we uncovered that green tea helped to reverse harmful changes in the brain, including the activation of microglia, which are immune cells in the brain often linked to neuroinflammation. The green tea diet also appeared to suppress several markers of neuroinflammation associated with BPA exposure.

Ultimately, our findings suggest that incorporating green tea into one’s diet may be a simple yet effective approach to mitigating anxiety disorders linked to environmental toxins like BPA. This study highlights the potential of natural remedies in combating modern-day chemical exposures.
Read More
9
Green tea nanoparticles ease anxiety
Green Tea Polyphenol Nanoparticles Reduce Anxiety Caused by Tobacco Smoking Withdrawal in Rats by Suppressing Neuroinflammation.
Highly relevant study findings
In our study, we aimed to understand how green tea, specifically its antioxidant-rich nanoparticles, might influence anxiety related to withdrawal from tobacco smoking. We conducted our experiment on rats that were exposed to tobacco smoke daily for several weeks. This exposure was known to induce anxiety-like behavior as part of the withdrawal process.

After 20 days of exposure, we administered green tea nanoparticles to half of the rats to see if this treatment could alleviate their anxiety levels. Our findings were promising; the rats that received the green tea nanoparticles showed reduced signs of anxiety compared to those that didn’t receive any treatment. We measured various factors in the rats’ brains, including markers of neuroinflammation and neuroplasticity, and found that the nanoparticles helped to regulate these responses.

Overall, this study suggests that green tea nanoparticles could play a protective role in managing tobacco withdrawal symptoms, particularly anxiety. We may have found a natural option to help ease the turmoil of quitting smoking.
Read More
9
EGCG reduces anxiety in withdrawal
Epigallocatechin Gallate Ameliorates Nicotine Withdrawal Conditions-Induced Somatic and Affective Behavior Changes in Mice and Its Molecular Mechanism.
Highly relevant to anxiety treatment
We explored how the green tea compound, epigallocatechin gallate (EGCG), affects anxiety and other behaviors during nicotine withdrawal (NW) in mice. Our study involved observing the behaviors of 24 male mice, divided into four groups, with one group receiving nicotine and another receiving EGCG after the withdrawal.

The results showed that mice experiencing nicotine withdrawal displayed increased food intake, body weight, and signs of anxiety, which highlights the struggles associated with quitting nicotine. However, when we introduced EGCG, the mice not only consumed less food and gained less weight but also showed a significant decrease in anxiety-like behaviors.

At a molecular level, we noted EGCG's positive effects on certain brain signals related to stress and appetite regulation. Specifically, it reduced the expression of corticotropin-releasing factor (CRF), which is associated with stress, while boosting pro-opiomelanocortin (POMC), a signaling molecule related to reducing anxiety and controlling appetite. It appears that EGCG can improve both somatic and emotional responses during nicotine withdrawal by balancing these signaling pathways in the brain.
Read More
8
EGCG improves anxiety in PD models
Neuroprotective effect of green tea extract (-)-epigallocatechin-3-gallate in a preformed fibril-induced mouse model of Parkinson's disease.
Study relevant but context diluted
We examined the effects of green tea extract, specifically a compound called (-)-epigallocatechin-3-gallate (EGCG), on anxiety levels in a mouse model of Parkinson's disease (PD). The study employed a structured design with control and treatment groups to effectively assess the impact of EGCG.

In our experiment, the chronic model of PD was created using α-synuclein preformed fibrils administered into the brains of female mice. We then observed the mice's behavior over several months, noting any changes in anxiety-like behavior and motor skills.

Our findings showed that EGCG pretreatment significantly reduced anxiety-like behaviors and motor impairments among the mice compared to those who only received the fibrillogenic treatment. This improvement suggests that EGCG could play a role in managing anxiety in the context of neurodegenerative diseases.

Overall, EGCG's neuroprotective effect appears to extend to emotional well-being, making it a noteworthy candidate for further research in the treatment of anxiety related to Parkinson's disease.
Read More

User Reviews

USERS' SCORE
Good
Based on 2 Reviews
8.5
  • All Reviews
  • Positive Reviews
  • Negative Reviews
8.3
Improves sleep quality
It works for me. I suffer from anxiety, which makes it difficult to fall asleep and stay asleep during stressful times. Without aid, my sleep varies greatly. OTC medications helped, but I was cautious about their long-term use. These Melatonin tablets have been effective; one tablet before bed generally suffices. Some reviews suggest it helps maintain good sleep rather than inducing it, but I find I feel notably more tired about half an hour after taking one, helping me to sleep. Overall, I’m genuinely impressed.
Read More
8.8
Beneficial for anxiety
I am impressed with NOW products. My son is autistic, and melatonin is essential for aiding his relaxation and sleep. I intend to purchase more NOW products for mood, anxiety, and sleep since their ingredients surpass those in store products. My son, who avoids prescription medication, appears to sleep better on this melatonin than with another brand. It's too early to be certain, but I believe the improved sleep is attributed to NOW melatonin.
Read More
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