We explored how green tea extract could fight cancer, particularly in a mouse model induced by a specific carcinogen. Our investigation included looking at its effects on three human cancer cell lines, revealing that the ethyl acetate fraction showed significant anti-cancer activity.
We discovered that this extract not only suppressed tumor growth but also improved key immune cytokine levels, suggesting potential health benefits. Importantly, the treatment did not harm the mice's blood parameters, indicating it is safe. This highlights the promising role of green tea extract in cancer prevention.
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Fig leaf extracts show promiseAntioxidant potential, antimicrobial activity, polyphenol profile analysis, and cytotoxicity against breast cancer cell lines of hydro-ethanolic extracts of leaves of ( L.) from Eastern Morocco.
Moderate relevance to cancer research.
We examined the effects of hydro-ethanolic extracts from fig leaves on breast cancer cells, focusing on their antioxidant and antimicrobial properties. Our analysis revealed that these extracts contained beneficial compounds like caffeine and polyphenols.
While the fig leaf extracts exhibited significant antioxidant activity and showed some promise in reducing cancer cell viability, the results did not indicate a robust effectiveness against breast cancer overall.
However, their rich nutrient profile suggests potential applications in medicine and natural health products.
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We examined the effects of green tea methanolic extract (GTME) on human liver cancer cells. The study revealed that GTME contains bioactive antioxidants and anticancer compounds that can significantly inhibit the growth of HepG2 cancer cells while sparing healthy cells.
We observed that GTME promotes apoptosis—a process that leads to cell death—in cancer cells, alongside evidence of its ability to halt cell cycle progression. However, further research, especially using animal models, is necessary to substantiate these promising findings.
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Natural extracts boost cancer therapyGreen Tea Leaves and Rosemary Extracts Selectively Induce Cell Death in Triple-Negative Breast Cancer Cells and Cancer Stem Cells and Enhance the Efficacy of Common Chemotherapeutics.
Highly relevant findings
We explored the potential of green tea and rosemary extracts in fighting triple-negative breast cancer. Our work focused on how these natural extracts affect cancer cells when used alone or in combination with common chemotherapy drugs like cisplatin and paclitaxel.
The results showed that both extracts effectively induced cell death in cancer cells, and they worked even better when paired with chemotherapy, improving treatment outcomes. Additionally, we found that the extracts were also effective against cancer stem cells, pointing to their potential for reducing relapse.
Importantly, these extracts appear to be well-tolerated, offering a promising approach to enhance existing cancer treatments.
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Lupalbigenin shows anti-cancer potentialDiscovery of flavonoid-containing compound Lupalbigenin as anti-NSCLC cancer agents via suppression of EGFR and ERK1/2 pathway.
High relevance for NSCLC research
We examined how Lupalbigenin, a flavonoid extracted from Derris scandens, could be effective against non-small cell lung cancer (NSCLC) driven by specific EGFR mutations. In our study, we created cell models expressing these mutations to test Lupalbigenin's cancer-fighting abilities.
We found that Lupalbigenin inhibited cell growth and triggered apoptosis by disrupting signals sent through the EGFR and ERK1/2 pathways. While results are promising, the focus on rare EGFR mutations means more research is needed before Lupalbigenin becomes a treatment option.
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