NOW Supplements Ubiquinol

I have completely lost my thyroid gland due to hypothyroidism. For two years, I’ve taken ubiquinol with omega daily. It provides me with strength and energy, even during fasting. Many of my friends now take it. It’s an essential supplement for memory and brain function, replacing my previous medications, and I always stock up on it.

Updated: Apr 2026

Liver Disease details

Chronic anaemia improvement

I take this for my liver health in my early 60s, and my symptoms of chronic anaemia have vanished, leaving me less fatigued. The ingredients are trustworthy and the small size makes it easy to take. Highly recommended for those dealing with liver disease.

Updated: Mar 2025

Blurred Vision details

Reduced blurred vision

I plan to continue. I am currently on my second tablet, hoping it will benefit my skin as I take one after dinner. However, I’m unsure of the effects of astaxanthin alone, as there are numerous other factors affecting my skin. I have noticed that my blurred vision seems less severe than before. In fact, during the afternoons, I find I can see better without relying on strong glasses.

Effective muscle treatment

Bone Pain details

It effectively alleviates muscle pain caused by prolonged use of statin drugs, specifically addressing bone pain concerns.

Ubiquinol reduces HF mortality, boosts exercise

Cardiovascular Disease details

SCIENTIFIC SCORE

Likely Very Effective

Qazi SU, Bin Naeem MA, Umar M, Zahid MJ, Kan Changez MI, et al. Evaluating the efficacy of ubiquinol in heart failure patients: a systematic review and meta-analysis. Future Cardiol. 2024;20:221. doi:10.1080/14796678.2024.2352308

We aimed to understand how ubiquinol, also known as coenzyme Q10 (CoQ-10), can impact those suffering from heart failure (HF). To do this, we conducted a thorough review of existing studies, searching databases like MEDLINE and the Cochrane Library for relevant literature.

Throughout our evaluation, we focused on key outcomes: whether CoQ-10 could reduce HF-related mortality, improve patients' exercise capacity, and affect the left ventricular ejection fraction (LVEF). Our analysis included findings from 16 different studies that provided intriguing insights.

Notably, we observed that CoQ-10 was effective in reducing HF-related mortality by an impressive 40%. Additionally, patients taking CoQ-10 reported enhanced exercise capacity, which is crucial for improving their quality of life. However, when it came to the left ventricular ejection fraction, the results were less clear; we found no significant difference, though we acknowledge that further research is needed to fully explore its potential effects in this area.

In summary, CoQ-10 shows promise in supporting heart failure patients by reducing mortality and boosting exercise capacity, but its role related to LVEF still warrants additional exploration.

Energy boost

Most Useful Review

4 people found this helpful

Since using Ubiquinol, I’ve noticed increased energy levels, which is great for cardiovascular health. Though it’s pricier, it’s worth it for the benefits, especially for those over 50. The brand is consistently reliable.

Updated: Mar 2026

Cold details

2 people found this helpful

I drank two packs - for the whole autumn, I NEVER got sick. There was not even a banal runny nose. Even in summer, I had no colds, despite often getting my feet wet in the rain. There was less 'pull' in my heart area, with unpleasant sensations a couple of times a week, but I haven't noticed them lately.

4 people found this helpful

Common Cold details

Effective against the common cold, I consumed a small bottle and subsequently purchased a larger one! Each tablet contains 100mg of ubiquinol, which efficiently produces energy in the body. Since I began taking it, my blood circulation has improved, making me feel less fatigued and more resilient to the cold. I take two tablets at night. I highly recommend it for those experiencing fatigue and stress due to aging.

Updated: Mar 2025

Food Poisoning details

Improved energy levels

2 people found this helpful

I recently began taking NOW Foods Ubiquinol and wanted to share my experience. Ubiquinol is the active form of CoQ10, chosen for its high bioavailability. From the start, I noticed a boost in energy and overall vitality. It supports my cardiovascular system, making me feel more alert during the day. My fatigue after exercising has decreased, allowing for faster recovery. The softgels are easy to use and swallow. Importantly, it contains no artificial additives and is suitable for vegetarians. I’m pleased to report no side effects. Overall, I highly recommend NOW Foods Ubiquinol for those seeking to enhance energy levels and cardiovascular support!

CoQ10 shows promise for arthritis

Arthritis details

Abdollahzad H, Aghdashi MA, Asghari Jafarabadi M, Alipour B. Effects of Coenzyme Q10 Supplementation on Inflammatory Cytokines (TNF-α, IL-6) and Oxidative Stress in Rheumatoid Arthritis Patients: A Randomized Controlled Trial. Arch Med Res. 2015;46:527. doi:10.1016/j.arcmed.2015.08.006

We explored the effects of Coenzyme Q10 (CoQ10) supplementation on individuals suffering from rheumatoid arthritis, a condition characterized by heightened levels of inflammation. Conducted as a double-blind, randomized controlled trial, our study included 44 participants, divided into two groups: one received 100 mg of CoQ10 daily, while the other took a placebo over a two-month period.

By measuring important markers like malondialdehyde (MDA), total antioxidant capacity (TAC), interleukin (IL)-6, and tumor necrosis factor alpha (TNF-α) before and after the intervention, we aimed to assess how CoQ10 might influence oxidative stress and inflammation.

The results indicated a significant decrease in serum MDA levels among those who took CoQ10, suggesting improved oxidative stress levels. Additionally, we noted a suppression of TNF-α, a key inflammatory cytokine. However, we found no significant changes in TAC or IL-6 levels between the two groups, which indicates that while CoQ10 seems to offer some benefits in reducing certain inflammatory markers, its overall effect on oxidative stress and other pro-inflammatory cytokines may be more limited than anticipated.

Thus, this study highlights the potential of CoQ10 as a supplementary treatment for managing inflammation in rheumatoid arthritis, although further research is needed to fully understand its role compared to other forms such as ubiquinol.

Eased muscle pain

Most Useful Review

5 people found this helpful

Highly recommended. CO Q10 is excellent for my arthritis, and with the addition of Ubiquinol, it absorbs faster. I recommend this product as it has been effective for everyone I know taking it, and my doctor confirmed it helps relieve muscle pain and arthritis.

Updated: Apr 2025

Anxiety details

This product is excellent. I have been using it for a long time and noticed positive results quickly, particularly in controlling my mood and anxiety. I highly recommend it.

Atrial Flutter details

Heart health improved

5 people found this helpful

Excellent! My mother, at 70 years old, experienced a serious heart attack and arrhythmia episodes, but she now feels fine. She is taking this alongside omega-3 supplements.

Mobility improvements noted

Back Pain details

5 people found this helpful

This product has shown noticeable improvements for me. At 50, my mobility is poor in my knees and joints, and I’m allergic to milk. After taking three pills a day, I noticed improvement within an hour—little to no pain when standing or sitting. It's like turning back time. Who wouldn’t want to combat free radicals? CoQ10 is essential!

Ubiquinol aids radiation gut health

Cancer details

Eraqi WA, El-Sabbagh WA, Aziz RK, Elshahed MS, Youssef NH, et al. Gastroprotective and microbiome-modulating effects of ubiquinol in rats with radiation-induced enteropathy. Anim Microbiome. 2024;6:40. doi:10.1186/s42523-024-00320-9

In a fascinating exploration of how ubiquinol may aid in managing cancer-related issues, we investigated its effects on radiation-induced enteropathy—a condition that can severely impact patients undergoing radiotherapy. Using a well-structured study design, we divided male albino rats into four groups: one that received only radiation, and three others that received varying treatments with ubiquinol either before or after exposure to radiation.

Our findings revealed that the rats treated with ubiquinol showed marked improvements in gut health when compared to those that only experienced radiation. We saw indications of enhanced healing in their intestinal tissues, including the recovery of important cells and reduced inflammation markers. Notably, the gut microbiomes of the ubiquinol-treated groups began to resemble those of healthy control rats, indicating that this treatment may help restore balance to the gut flora disrupted by radiation.

This research highlights the potential of ubiquinol not only to protect the gut from radiation damage but also to support overall health in cancer patients by aiding in the recovery of gut microbiota diversity. It seems that ubiquinol could indeed play a significant role in enhancing the quality of life for individuals undergoing cancer treatments, particularly those affected by gastrointestinal side effects.

7.5

Prevents disease progression

Most Useful Review

8 people found this helpful

Excellent ubiquinol. It is the reduced form of Coenzyme Q10, meaning it is absorbed more efficiently. This potent antioxidant is often lacking in our diets, especially after 30, leading to quicker skin aging and potentially diminishing organ and cognitive function. Ubiquinol is crucial for countering free radicals, which can cause cellular dysfunction and elevate cancer risk. Sufficient intake can avert various diseases, from cancer to Alzheimer's. Ubiquinol has also proven effective in treating COVID-19 and its aftermath. I highly recommend it for regular use and therapeutic purposes!

Updated: Apr 2025

Hypertension details

Ubiquinol shows partial benefits

Kuropatkina T, Pavlova O, Gulyaev M, Pirogov Y, Khutorova A, et al. Sex-Dependent Protective Effect of Combined Application of Solubilized Ubiquinol and Selenium on Monocrotaline-Induced Pulmonary Hypertension in Wistar Rats. Antioxidants (Basel). 2022;11. doi:10.3390/antiox11030549

We explored the impact of ubiquinol on pulmonary hypertension using a model that mimics this serious condition. In our study, rats were injected with monocrotaline, a substance known to induce pulmonary hypertension. Over the course of the experiment, we provided various groups of these rats with different treatments, including solubilized ubiquinol and selenium, to see how these substances could protect against the effects of the disease.

The results were quite enlightening. We observed that ubiquinol administered intravenously had a protective effect, especially in male rats. This treatment reduced the right ventricle hypertrophy and lung mass commonly associated with elevated blood pressure in the lungs. Interestingly, when we combined ubiquinol with selenium, we found a less severe increase in right ventricle systolic pressure in males but not in females, indicating a sex-dependent effect that suggests females may not experience the same benefits from this combination treatment.

However, it's worth noting that the relative mass of the right ventricle did not show significant differences across all treatment groups. This suggests that while ubiquinol can be beneficial, particularly in males, the overall benefits may be limited and not as pronounced in females. Magnetic resonance imaging further revealed impaired lung perfusion in most rats tested, with signs of pulmonary fibrosis only present in the group receiving ubiquinol.

Overall, while ubiquinol shows potential in addressing pulmonary hypertension, its effectiveness might vary based on sex and should be approached with cautious optimism.

Highly effective

Most Useful Review

1 people found this helpful

Excellent quality and dosage. I highly recommend it for managing hypertension, especially in conjunction with PQQ.

Updated: Mar 2026

Migraine details

After using Coenzyme Q10, I switched to reduced ubiquinol for better efficacy. Previously suffering from migraines, since I began taking ubiquinol, I haven't experienced any migraines.

Sleep Apnea details

Increased energy levels

8 people found this helpful

Taking Ubiquinol has proven crucial for my mitochondria, helping me combat sleep apnea. I feel more energetic and less sleepy after lunch. My mental clarity under work stress has improved significantly. It's highly beneficial for heart patients and diabetics, and despite its cost, I would definitely reorder.

Ubiquinol shows promise in stroke

Stroke details

SCIENTIFIC SCORE

Moderately Effective

Based on 2 Researches

Jia Z, Yu X, Wang X, Li J. Therapeutic Effects of Coenzyme Q10 in the Treatment of Ischemic Stroke. Curr Nutr Rep. 2024;13:679. doi:10.1007/s13668-024-00568-2

We explored how ubiquinol, a form of coenzyme Q10, may help in treating ischemic stroke. The brain is particularly vulnerable after a stroke due to oxidative stress, which can lead to further damage. Thus, the potential of antioxidants like ubiquinol becomes very interesting.

Recent studies suggest that ubiquinol can protect the brain in several ways. It works against oxidative stress, inflammation, and cell death, potentially offering a multi-faceted approach to treating ischemic stroke. Evidence has been gathered from multiple angles—laboratory experiments, animal studies, and clinical observations—to highlight these protective effects.

Our findings emphasize the promising role of ubiquinol in neuroprotection following ischemic stroke. Given the significant deficiency of its reduced form in the brain, ubiquinol could serve as a valuable candidate for treatment and prevention strategies moving forward.

Improved potency

Most Useful Review

1 people found this helpful

Perfectly! It helped my husband cope with the side effects of statins after his stroke. We noticed a significant decline in potency as a side effect of the statins. However, since using this coenzyme along with astaxanthin from the same brand, things have greatly improved.

Updated: Apr 2025

Swollen Lymph Nodes details

10 people found this helpful

There are improvements. About eight months ago, my heart problems worsened. Appointments yielded no results, and I developed swollen lymph nodes. I had to figure it out myself and discovered Ubiquinol. After three days of taking it, I felt an improvement. To say I am delighted is an understatement; I no longer wake up at night feeling suffocated, and my sleep has improved. My energy levels have returned. Previously, neither sleep nor rest helped me regain my strength. At 60+, I believe I can manage the issue with Ubiquinol.

An excellent remedy for those lacking energy and suffering from hypothyroidism or adrenal depletion. The effect is cumulative; I noticed a clear result after a month of taking it.

Adrenal Gland Disorder details

Successful IVF preparation

Autoimmune Disorder details

On my reproductive specialist's recommendation, I took Ubiquinol as preparation for my IVF protocol. I consumed one capsule daily for two months, which yielded good results despite a low AMH level. Highly recommend!

Frozen Shoulder details

Reduced shoulder pain

7 people found this helpful

I heard that ubiquinol may help with nerve and tendon sheath adhesion, particularly for conditions such as spinocerebellar degeneration. After taking 200mg daily for a month, I noticed significant improvements in my forty shoulders following rotator cuff detachment. Initially, there was pain akin to adhesions in my occipital nerve, but this decreased after about three months of taking it, leading to better balance.

Knee Pain details

Ubiquinol is the most effective form of Q10 for me. The dosage is just right, and it has helped my knee pain immensely. I even returned to sports and CrossFit.

Supports cholesterol management

High Cholesterol details

8 people found this helpful

I take Ubiquinol for statin-related CoQ10 deficiency. My father, who had a myocardial infarction, also takes it twice daily to counteract the effects of statins. It’s more affordable to buy it from iHerb, which is helpful.