' 
SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
6.8
USERS' SCORE
Very Good
Based on 9 Reviews
8.9
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin D3 (as Cholecalciferol) (From Lanolin)
1,250 mcg (50,000 IU)
6250%
Top Medical Research Studies
9
Vitamin D3 may alleviate fibromyalgia
Efficacy of Vitamin D Supplementation in the Improvement of Clinical Status in Patients Diagnosed with Fibromyalgia Syndrome: A Systematic Review.
Highly relevant to study focus.
We conducted a thorough review of the existing literature to understand how vitamin D3 supplementation affects those suffering from fibromyalgia. This condition is often marked by widespread pain and fatigue, and we wanted to see if vitamin D3 could help alleviate these troubling symptoms.
In our search, we scoured various databases for studies published between January 2011 and May 2021. This included randomized controlled trials, observational studies, and other well-documented research focused explicitly on fibromyalgia. Out of the 2,651 studies retrieved, 12 met our strict criteria for inclusion, of which 11 were of high quality, showing minimal bias.
The results were promising, as 11 of those high-quality studies indicated a significant positive impact on the clinical status of fibromyalgia patients who received vitamin D3. This suggests that vitamin D3 might play an important role in managing fibromyalgia symptoms.
While our findings point towards the benefits of vitamin D3 supplementation, they also highlight the need for further research. As we continue to explore effective treatments for fibromyalgia, vitamin D3 stands out as a potentially beneficial option worth considering for patients seeking relief.
In our search, we scoured various databases for studies published between January 2011 and May 2021. This included randomized controlled trials, observational studies, and other well-documented research focused explicitly on fibromyalgia. Out of the 2,651 studies retrieved, 12 met our strict criteria for inclusion, of which 11 were of high quality, showing minimal bias.
The results were promising, as 11 of those high-quality studies indicated a significant positive impact on the clinical status of fibromyalgia patients who received vitamin D3. This suggests that vitamin D3 might play an important role in managing fibromyalgia symptoms.
While our findings point towards the benefits of vitamin D3 supplementation, they also highlight the need for further research. As we continue to explore effective treatments for fibromyalgia, vitamin D3 stands out as a potentially beneficial option worth considering for patients seeking relief.
Read More
0
Vitamin D shows no benefit for FM
Efficacy and safety of weekly vitamin D in patients with fibromyalgia: 12-week, double-blind, randomized, controlled placebo trial.
Study directly addresses vitamin D use
We conducted a rigorous clinical trial to explore whether vitamin D supplementation could help alleviate symptoms in patients with fibromyalgia (FM). Over 12 weeks, female participants aged 18 and older, who met established criteria for FM, were randomly assigned to receive either a weekly dose of 50,000 IU of vitamin D or a placebo.
This study was designed to be double-blind, ensuring that neither the participants nor the researchers knew who received the vitamin D or placebo to eliminate bias in the results. At the beginning of the study, we measured pain levels and quality of life using validated tools, specifically focusing on the Visual Analog Scale (VAS) and the Fibromyalgia Impact Questionnaire (FIQ).
However, our findings indicated that there was no significant difference between the vitamin D group and the placebo group in terms of pain relief or overall improvement in FM symptoms. Despite confirming that vitamin D levels increased in those receiving the supplement, this did not translate into better outcomes for the patients involved.
Overall, the study clearly suggests that vitamin D supplementation may not be effective in improving symptoms for fibromyalgia patients, challenging the existing beliefs around vitamin D’s role in treating this condition.
This study was designed to be double-blind, ensuring that neither the participants nor the researchers knew who received the vitamin D or placebo to eliminate bias in the results. At the beginning of the study, we measured pain levels and quality of life using validated tools, specifically focusing on the Visual Analog Scale (VAS) and the Fibromyalgia Impact Questionnaire (FIQ).
However, our findings indicated that there was no significant difference between the vitamin D group and the placebo group in terms of pain relief or overall improvement in FM symptoms. Despite confirming that vitamin D levels increased in those receiving the supplement, this did not translate into better outcomes for the patients involved.
Overall, the study clearly suggests that vitamin D supplementation may not be effective in improving symptoms for fibromyalgia patients, challenging the existing beliefs around vitamin D’s role in treating this condition.
Read More
9
Vitamin D3 improves fibromyalgia symptoms
Efficacy of vitamin D replacement therapy on patients with chronic nonspecific widespread musculoskeletal pain with vitamin D deficiency.
Highly relevant to fibromyalgia treatment
We aimed to understand how vitamin D3 replacement therapy could help alleviate symptoms for those suffering from chronic widespread musculoskeletal pain (CWP) and fibromyalgia (FM). Our research included patients who had low levels of vitamin D and experienced significant musculoskeletal discomfort.
To see if vitamin D3 could make a difference, we administered a treatment of 50,000 IU of oral vitamin D3 weekly for three months. Before and after this treatment, we assessed various health markers, like pain severity, fatigue levels, depression, and quality of life.
The results were quite promising. Patients showed a significant increase in vitamin D levels post-treatment, rising from an average of 10.6 ng/mL to 46.5 ng/mL. Alongside this improvement, there was a marked reduction in pain, fatigue, and depressive symptoms, along with enhanced overall quality of life. A notable number of patients reported satisfaction with the treatment, and the percentage of those meeting the criteria for fibromyalgia decreased after vitamin D3 therapy.
Overall, this study suggests that vitamin D3 replacement can lead to meaningful improvements for individuals with fibromyalgia and chronic pain, emphasizing the need to check for vitamin D deficiency in these patients.
To see if vitamin D3 could make a difference, we administered a treatment of 50,000 IU of oral vitamin D3 weekly for three months. Before and after this treatment, we assessed various health markers, like pain severity, fatigue levels, depression, and quality of life.
The results were quite promising. Patients showed a significant increase in vitamin D levels post-treatment, rising from an average of 10.6 ng/mL to 46.5 ng/mL. Alongside this improvement, there was a marked reduction in pain, fatigue, and depressive symptoms, along with enhanced overall quality of life. A notable number of patients reported satisfaction with the treatment, and the percentage of those meeting the criteria for fibromyalgia decreased after vitamin D3 therapy.
Overall, this study suggests that vitamin D3 replacement can lead to meaningful improvements for individuals with fibromyalgia and chronic pain, emphasizing the need to check for vitamin D deficiency in these patients.
Read More
Most Useful Reviews
8.8
Strong bones benefit
Great! Vitamin D3 is essential. It's a high-quality product with great ingredients, easy to take with water. Since we often lack sunlight, this vitamin D3 quickly boosts my immunity. I recommend getting an exam to check for deficiency and repeating it after three months to observe improvements in bone strength and pain relief. I've been using this brand for two years, and I'm very satisfied, especially with my fibromyalgia.
Read More
8.8
Improved recovery process
Important, good quality, non-GMO, and reasonably priced. This vitamin is crucial for life. I take a high amount due to my fibromyalgia, needing elevated levels for recovery. Thank you, iHerb.
Read More
8.8
Increased immunity
Vitamin D in high dosage! As a fibromyalgia sufferer, I follow the Coimbra protocol, and this dosage is excellent for improving my immunity, especially in Brazil’s low-sun months.
Read More
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Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
6.8
9
Vitamin D3 may alleviate fibromyalgia
Efficacy of Vitamin D Supplementation in the Improvement of Clinical Status in Patients Diagnosed with Fibromyalgia Syndrome: A Systematic Review.
Highly relevant to study focus.
We conducted a thorough review of the existing literature to understand how vitamin D3 supplementation affects those suffering from fibromyalgia. This condition is often marked by widespread pain and fatigue, and we wanted to see if vitamin D3 could help alleviate these troubling symptoms.
In our search, we scoured various databases for studies published between January 2011 and May 2021. This included randomized controlled trials, observational studies, and other well-documented research focused explicitly on fibromyalgia. Out of the 2,651 studies retrieved, 12 met our strict criteria for inclusion, of which 11 were of high quality, showing minimal bias.
The results were promising, as 11 of those high-quality studies indicated a significant positive impact on the clinical status of fibromyalgia patients who received vitamin D3. This suggests that vitamin D3 might play an important role in managing fibromyalgia symptoms.
While our findings point towards the benefits of vitamin D3 supplementation, they also highlight the need for further research. As we continue to explore effective treatments for fibromyalgia, vitamin D3 stands out as a potentially beneficial option worth considering for patients seeking relief.
In our search, we scoured various databases for studies published between January 2011 and May 2021. This included randomized controlled trials, observational studies, and other well-documented research focused explicitly on fibromyalgia. Out of the 2,651 studies retrieved, 12 met our strict criteria for inclusion, of which 11 were of high quality, showing minimal bias.
The results were promising, as 11 of those high-quality studies indicated a significant positive impact on the clinical status of fibromyalgia patients who received vitamin D3. This suggests that vitamin D3 might play an important role in managing fibromyalgia symptoms.
While our findings point towards the benefits of vitamin D3 supplementation, they also highlight the need for further research. As we continue to explore effective treatments for fibromyalgia, vitamin D3 stands out as a potentially beneficial option worth considering for patients seeking relief.
Read More
9
Vitamin D3 improves fibromyalgia symptoms
Efficacy of vitamin D replacement therapy on patients with chronic nonspecific widespread musculoskeletal pain with vitamin D deficiency.
Highly relevant to fibromyalgia treatment
We aimed to understand how vitamin D3 replacement therapy could help alleviate symptoms for those suffering from chronic widespread musculoskeletal pain (CWP) and fibromyalgia (FM). Our research included patients who had low levels of vitamin D and experienced significant musculoskeletal discomfort.
To see if vitamin D3 could make a difference, we administered a treatment of 50,000 IU of oral vitamin D3 weekly for three months. Before and after this treatment, we assessed various health markers, like pain severity, fatigue levels, depression, and quality of life.
The results were quite promising. Patients showed a significant increase in vitamin D levels post-treatment, rising from an average of 10.6 ng/mL to 46.5 ng/mL. Alongside this improvement, there was a marked reduction in pain, fatigue, and depressive symptoms, along with enhanced overall quality of life. A notable number of patients reported satisfaction with the treatment, and the percentage of those meeting the criteria for fibromyalgia decreased after vitamin D3 therapy.
Overall, this study suggests that vitamin D3 replacement can lead to meaningful improvements for individuals with fibromyalgia and chronic pain, emphasizing the need to check for vitamin D deficiency in these patients.
To see if vitamin D3 could make a difference, we administered a treatment of 50,000 IU of oral vitamin D3 weekly for three months. Before and after this treatment, we assessed various health markers, like pain severity, fatigue levels, depression, and quality of life.
The results were quite promising. Patients showed a significant increase in vitamin D levels post-treatment, rising from an average of 10.6 ng/mL to 46.5 ng/mL. Alongside this improvement, there was a marked reduction in pain, fatigue, and depressive symptoms, along with enhanced overall quality of life. A notable number of patients reported satisfaction with the treatment, and the percentage of those meeting the criteria for fibromyalgia decreased after vitamin D3 therapy.
Overall, this study suggests that vitamin D3 replacement can lead to meaningful improvements for individuals with fibromyalgia and chronic pain, emphasizing the need to check for vitamin D deficiency in these patients.
Read More
8
Vitamin D improves fibromyalgia treatment
Can the Combination of Rehabilitation and Vitamin D Supplementation Improve Fibromyalgia Symptoms at All Ages?
Study combines vitamin D and rehab
We conducted a study to explore the effects of vitamin D3 supplementation coupled with rehabilitation on fibromyalgia symptoms among different age groups. The research involved 80 patients, split into two age groups: those aged 50 and younger, and those over 50. Each group received a high dose of vitamin D (50,000 IU) weekly for three months, alongside a structured rehabilitation protocol.
Through regular assessments over six months, we noted distinct improvements based on age. For younger patients, high-dose vitamin D led to impressive short-term relief from musculoskeletal pain and enhanced long-term functional capacity. On the other hand, older patients experienced significant improvements in their overall quality of life and management of musculoskeletal pain over time.
These findings suggest that vitamin D can play a beneficial role in managing fibromyalgia symptoms, emphasizing the importance of considering age in treatment approaches. Essentially, while the young benefited in terms of functionality, the elderly saw improvements in their quality of life and pain management after vitamin D supplementation.
Through regular assessments over six months, we noted distinct improvements based on age. For younger patients, high-dose vitamin D led to impressive short-term relief from musculoskeletal pain and enhanced long-term functional capacity. On the other hand, older patients experienced significant improvements in their overall quality of life and management of musculoskeletal pain over time.
These findings suggest that vitamin D can play a beneficial role in managing fibromyalgia symptoms, emphasizing the importance of considering age in treatment approaches. Essentially, while the young benefited in terms of functionality, the elderly saw improvements in their quality of life and pain management after vitamin D supplementation.
Read More
8
Vitamin D3 reduces fibromyalgia pain
Effects of vitamin D on patients with fibromyalgia syndrome: a randomized placebo-controlled trial.
Highly relevant to research question
We embarked on a fascinating journey to understand whether vitamin D3 (cholecalciferol) supplementation could alleviate pain in women suffering from fibromyalgia syndrome (FMS). Our study involved thirty women diagnosed with FMS, all of whom had low serum levels of calcifediol. To investigate the potential benefits, we split the participants into two groups: one received vitamin D3 supplements, while the other received a placebo.
Over the course of 20 weeks, we aimed to raise the serum calcifediol levels of the treatment group to between 32 and 48 ng/mL. After this period of supplementation, we assessed their pain levels using a visual analog scale, alongside other health surveys that measured depression and the impact of fibromyalgia on their daily lives.
Excitingly, we found that the women in the treatment group experienced a significant reduction in pain compared to those in the control group. This improvement was not only recorded in pain scores but was also reflected in their overall physical functioning. It appears that optimizing vitamin D levels may positively influence pain perception in fibromyalgia patients.
However, while the results are promising, we recognize that our study had a relatively small sample size. This means further research with a larger group is necessary to fully confirm these findings. Overall, our findings suggest that vitamin D3 supplementation could be a viable and low-risk option for managing fibromyalgia pain.
Over the course of 20 weeks, we aimed to raise the serum calcifediol levels of the treatment group to between 32 and 48 ng/mL. After this period of supplementation, we assessed their pain levels using a visual analog scale, alongside other health surveys that measured depression and the impact of fibromyalgia on their daily lives.
Excitingly, we found that the women in the treatment group experienced a significant reduction in pain compared to those in the control group. This improvement was not only recorded in pain scores but was also reflected in their overall physical functioning. It appears that optimizing vitamin D levels may positively influence pain perception in fibromyalgia patients.
However, while the results are promising, we recognize that our study had a relatively small sample size. This means further research with a larger group is necessary to fully confirm these findings. Overall, our findings suggest that vitamin D3 supplementation could be a viable and low-risk option for managing fibromyalgia pain.
Read More
8
Vitamin D3 may alleviate symptoms
1-α hydroxylation defect in postural orthostatic tachycardia syndrome: remission with calcitriol supplementation.
Majority of symptoms unclear
We explored the relationship between vitamin D3, particularly its active form calcitriol, and fibromyalgia symptoms through the case of a 37-year-old woman diagnosed with multiple health issues, including fibromyalgia. As part of her treatment for postural orthostatic tachycardia syndrome (POTS), she was administered calcitriol after lab tests indicated deficiencies in specific vitamin D levels.
Following five months of treatment, she reported a significant improvement in her symptoms, including a notable decrease in palpitations and increased ability to work full-time. After three months of taking calcitriol, her 1,25(OH)(2) vitamin D3 levels did improve, aligning better with normal ranges. This case suggests exploring the potential benefits of vitamin D3 supplementation, particularly for individuals suffering from fibromyalgia alongside conditions like POTS. However, it’s important to highlight that further research is needed to conclusively establish the direct impact of vitamin D3 specifically on fibromyalgia symptoms isolated from other health issues.
Following five months of treatment, she reported a significant improvement in her symptoms, including a notable decrease in palpitations and increased ability to work full-time. After three months of taking calcitriol, her 1,25(OH)(2) vitamin D3 levels did improve, aligning better with normal ranges. This case suggests exploring the potential benefits of vitamin D3 supplementation, particularly for individuals suffering from fibromyalgia alongside conditions like POTS. However, it’s important to highlight that further research is needed to conclusively establish the direct impact of vitamin D3 specifically on fibromyalgia symptoms isolated from other health issues.
Read More
User Reviews
USERS' SCORE
Very Good
Based on 9 Reviews
8.9
9.5
Managed sleep apnea
Vitamin D is essential. After taking this high dose with magnesium, zinc, and K2 for six weeks, my levels improved significantly. I plan to reduce my dose now. I noticed my sleep apnea returned when I stopped it, but it resolved quickly when I resumed. This quality product is critical for my fibromyalgia recovery. Thank you, iHerb.
Read More
9.5
Enhanced energy levels
Great choice! I take two capsules monthly, keeping my levels at around 70 ng/mL. It aids in energy, muscle regeneration, and restful sleep. Doctors often overlook that fibromyalgia symptoms can stem from low vitamin D levels.
8.8
Strong bones benefit
Great! Vitamin D3 is essential. It's a high-quality product with great ingredients, easy to take with water. Since we often lack sunlight, this vitamin D3 quickly boosts my immunity. I recommend getting an exam to check for deficiency and repeating it after three months to observe improvements in bone strength and pain relief. I've been using this brand for two years, and I'm very satisfied, especially with my fibromyalgia.
Read More
8.8
Improved recovery process
Important, good quality, non-GMO, and reasonably priced. This vitamin is crucial for life. I take a high amount due to my fibromyalgia, needing elevated levels for recovery. Thank you, iHerb.
8.8
Increased immunity
Vitamin D in high dosage! As a fibromyalgia sufferer, I follow the Coimbra protocol, and this dosage is excellent for improving my immunity, especially in Brazil’s low-sun months.
