We aimed to understand how vitamin D3 replacement therapy could help alleviate symptoms for those suffering from chronic widespread musculoskeletal pain (CWP) and fibromyalgia (FM). Our research included patients who had low levels of vitamin D and experienced significant musculoskeletal discomfort.
To see if vitamin D3 could make a difference, we administered a treatment of 50,000 IU of oral vitamin D3 weekly for three months. Before and after this treatment, we assessed various health markers, like pain severity, fatigue levels, depression, and quality of life.
The results were quite promising. Patients showed a significant increase in vitamin D levels post-treatment, rising from an average of 10.6 ng/mL to 46.5 ng/mL. Alongside this improvement, there was a marked reduction in pain, fatigue, and depressive symptoms, along with enhanced overall quality of life. A notable number of patients reported satisfaction with the treatment, and the percentage of those meeting the criteria for fibromyalgia decreased after vitamin D3 therapy.
Overall, this study suggests that vitamin D3 replacement can lead to meaningful improvements for individuals with fibromyalgia and chronic pain, emphasizing the need to check for vitamin D deficiency in these patients.