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NOW Supplements Vitamin D-3
SCIENTIFIC SCORE
Questionable
Based on 25 Researches
6.4
USERS' SCORE
Good
Based on 9 Reviews
8.7
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin D3 (as Cholecalciferol) (From Lanolin)
1,250 mcg (50,000 IU)
6250%

Top Medical Research Studies

9
Vitamin D improves fibromyalgia symptoms
The effect of vitamin D treatment on quality of life in patients with fibromyalgia.
High relevance to fibromyalgia treatment
We aimed to explore the effectiveness of vitamin D supplementation in alleviating the symptoms of fibromyalgia—a condition marked by chronic pain, fatigue, and cognitive challenges. Our research included a group of 180 women, aged 18 to 65, who met the criteria for fibromyalgia. We administered a high-dose vitamin D3 supplement of 50,000 IU over a span of 12 weeks and assessed the impact on their quality of life through the Fibromyalgia Impact Questionnaire (FIQ) and the Visual Analog Scale (VAS).

After the treatment, we observed significant improvements in both FIQ and VAS scores, indicating a notable positive effect of vitamin D on the quality of life and pain reduction in these patients. Particularly, the results suggested that many of the participants had a pre-existing vitamin D deficiency, which is more common among individuals with fibromyalgia.

Overall, this study highlights the potential benefits of vitamin D supplementation for those suffering from fibromyalgia and encourages further investigation into its role in managing this challenging condition.
Read More
9
Vitamin D aids fibromyalgia treatment
Efficacy of Vitamin D Supplementation in the Improvement of Clinical Status in Patients Diagnosed with Fibromyalgia Syndrome: A Systematic Review.
Directly studies vitamin D effects
We explored the potential benefits of vitamin D supplementation for individuals suffering from fibromyalgia, a condition known for causing widespread pain and fatigue. Our review involved examining various studies, including randomized controlled trials and observational studies, focusing on those published between early 2011 and May 2021.

After a thorough search, we found a total of 2,651 studies, narrowing it down to 12 high-quality studies that met our criteria. Remarkably, 11 of these studies presented clear evidence of improvement in clinical status and various related outcomes after participants received vitamin D supplements. This suggests that vitamin D could play a key role in alleviating fibromyalgia symptoms.

Our findings highlight a promising link between vitamin D supplementation and the enhancement of health in fibromyalgia patients. As we move forward, we recognize the need for continued research to further standardize how we detect and treat this complex condition, potentially offering cost-effective solutions that incorporate vitamin D.
Read More
9
Vitamin D3 may alleviate fibromyalgia
Efficacy of Vitamin D Supplementation in the Improvement of Clinical Status in Patients Diagnosed with Fibromyalgia Syndrome: A Systematic Review.
Highly relevant to study focus.
We conducted a thorough review of the existing literature to understand how vitamin D3 supplementation affects those suffering from fibromyalgia. This condition is often marked by widespread pain and fatigue, and we wanted to see if vitamin D3 could help alleviate these troubling symptoms.

In our search, we scoured various databases for studies published between January 2011 and May 2021. This included randomized controlled trials, observational studies, and other well-documented research focused explicitly on fibromyalgia. Out of the 2,651 studies retrieved, 12 met our strict criteria for inclusion, of which 11 were of high quality, showing minimal bias.

The results were promising, as 11 of those high-quality studies indicated a significant positive impact on the clinical status of fibromyalgia patients who received vitamin D3. This suggests that vitamin D3 might play an important role in managing fibromyalgia symptoms.

While our findings point towards the benefits of vitamin D3 supplementation, they also highlight the need for further research. As we continue to explore effective treatments for fibromyalgia, vitamin D3 stands out as a potentially beneficial option worth considering for patients seeking relief.
Read More

Most Useful Reviews

8.8
Strong bones benefit
Great! Vitamin D3 is essential. It's a high-quality product with great ingredients, easy to take with water. Since we often lack sunlight, this vitamin D3 quickly boosts my immunity. I recommend getting an exam to check for deficiency and repeating it after three months to observe improvements in bone strength and pain relief. I've been using this brand for two years, and I'm very satisfied, especially with my fibromyalgia.
Read More
8.8
Improved recovery process
Important, good quality, non-GMO, and reasonably priced. This vitamin is crucial for life. I take a high amount due to my fibromyalgia, needing elevated levels for recovery. Thank you, iHerb.
Read More
8.8
Increased immunity
Vitamin D in high dosage! As a fibromyalgia sufferer, I follow the Coimbra protocol, and this dosage is excellent for improving my immunity, especially in Brazil’s low-sun months.
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 25 Researches
6.4
  • All Researches
9
Vitamin D improves fibromyalgia symptoms
The effect of vitamin D treatment on quality of life in patients with fibromyalgia.
High relevance to fibromyalgia treatment
We aimed to explore the effectiveness of vitamin D supplementation in alleviating the symptoms of fibromyalgia—a condition marked by chronic pain, fatigue, and cognitive challenges. Our research included a group of 180 women, aged 18 to 65, who met the criteria for fibromyalgia. We administered a high-dose vitamin D3 supplement of 50,000 IU over a span of 12 weeks and assessed the impact on their quality of life through the Fibromyalgia Impact Questionnaire (FIQ) and the Visual Analog Scale (VAS).

After the treatment, we observed significant improvements in both FIQ and VAS scores, indicating a notable positive effect of vitamin D on the quality of life and pain reduction in these patients. Particularly, the results suggested that many of the participants had a pre-existing vitamin D deficiency, which is more common among individuals with fibromyalgia.

Overall, this study highlights the potential benefits of vitamin D supplementation for those suffering from fibromyalgia and encourages further investigation into its role in managing this challenging condition.
Read More
9
Vitamin D aids fibromyalgia treatment
Efficacy of Vitamin D Supplementation in the Improvement of Clinical Status in Patients Diagnosed with Fibromyalgia Syndrome: A Systematic Review.
Directly studies vitamin D effects
We explored the potential benefits of vitamin D supplementation for individuals suffering from fibromyalgia, a condition known for causing widespread pain and fatigue. Our review involved examining various studies, including randomized controlled trials and observational studies, focusing on those published between early 2011 and May 2021.

After a thorough search, we found a total of 2,651 studies, narrowing it down to 12 high-quality studies that met our criteria. Remarkably, 11 of these studies presented clear evidence of improvement in clinical status and various related outcomes after participants received vitamin D supplements. This suggests that vitamin D could play a key role in alleviating fibromyalgia symptoms.

Our findings highlight a promising link between vitamin D supplementation and the enhancement of health in fibromyalgia patients. As we move forward, we recognize the need for continued research to further standardize how we detect and treat this complex condition, potentially offering cost-effective solutions that incorporate vitamin D.
Read More
9
Fibromyalgia treatment approach explored
Fibromyalgia associated with Chagas' disease treated with nutraceuticals.
Vitamin D treatment context highlighted
We examined a unique case involving a 61-year-old woman with Chagas' disease who was also diagnosed with fibromyalgia. This patient had been suffering from severe gastrointestinal issues for years, alongside diffuse body pain and sleep difficulties. She was treated with a combination of psychotherapy, vitamin D supplementation, and physical exercise, specifically Pilates and walking.

Remarkably, after six months of this treatment regimen, the patient showed significant improvement. Her pain was greatly reduced, anxiety levels were controlled, and her vitamin D levels became normal. This raises an interesting point about the role of vitamin D in treating fibromyalgia, although we must note that the positive effects could not be attributed solely to vitamin D, as other treatments were also involved.

Our exploration of related literature revealed various connections between infections and fibromyalgia; however, there was no specific mention of Trypanosoma cruzi, the parasite responsible for Chagas' disease, being linked to fibromyalgia symptoms. This suggests that while infectious agents might play a role in fibromyalgia, the relationship with T. cruzi in this context remains uncertain.

Overall, this case highlights a promising alternative treatment approach for fibromyalgia using vitamin D, alongside other supportive measures but also cautions us to consider the multifaceted nature of the condition.
Read More
9
Vitamin D3 may alleviate fibromyalgia
Efficacy of Vitamin D Supplementation in the Improvement of Clinical Status in Patients Diagnosed with Fibromyalgia Syndrome: A Systematic Review.
Highly relevant to study focus.
We conducted a thorough review of the existing literature to understand how vitamin D3 supplementation affects those suffering from fibromyalgia. This condition is often marked by widespread pain and fatigue, and we wanted to see if vitamin D3 could help alleviate these troubling symptoms.

In our search, we scoured various databases for studies published between January 2011 and May 2021. This included randomized controlled trials, observational studies, and other well-documented research focused explicitly on fibromyalgia. Out of the 2,651 studies retrieved, 12 met our strict criteria for inclusion, of which 11 were of high quality, showing minimal bias.

The results were promising, as 11 of those high-quality studies indicated a significant positive impact on the clinical status of fibromyalgia patients who received vitamin D3. This suggests that vitamin D3 might play an important role in managing fibromyalgia symptoms.

While our findings point towards the benefits of vitamin D3 supplementation, they also highlight the need for further research. As we continue to explore effective treatments for fibromyalgia, vitamin D3 stands out as a potentially beneficial option worth considering for patients seeking relief.
Read More
9
Vitamin D3 improves fibromyalgia symptoms
Efficacy of vitamin D replacement therapy on patients with chronic nonspecific widespread musculoskeletal pain with vitamin D deficiency.
Highly relevant to fibromyalgia treatment
We aimed to understand how vitamin D3 replacement therapy could help alleviate symptoms for those suffering from chronic widespread musculoskeletal pain (CWP) and fibromyalgia (FM). Our research included patients who had low levels of vitamin D and experienced significant musculoskeletal discomfort.

To see if vitamin D3 could make a difference, we administered a treatment of 50,000 IU of oral vitamin D3 weekly for three months. Before and after this treatment, we assessed various health markers, like pain severity, fatigue levels, depression, and quality of life.

The results were quite promising. Patients showed a significant increase in vitamin D levels post-treatment, rising from an average of 10.6 ng/mL to 46.5 ng/mL. Alongside this improvement, there was a marked reduction in pain, fatigue, and depressive symptoms, along with enhanced overall quality of life. A notable number of patients reported satisfaction with the treatment, and the percentage of those meeting the criteria for fibromyalgia decreased after vitamin D3 therapy.

Overall, this study suggests that vitamin D3 replacement can lead to meaningful improvements for individuals with fibromyalgia and chronic pain, emphasizing the need to check for vitamin D deficiency in these patients.
Read More

User Reviews

USERS' SCORE
Good
Based on 9 Reviews
8.7
  • All Reviews
  • Positive Reviews
  • Negative Reviews
8.8
Strong bones benefit
Great! Vitamin D3 is essential. It's a high-quality product with great ingredients, easy to take with water. Since we often lack sunlight, this vitamin D3 quickly boosts my immunity. I recommend getting an exam to check for deficiency and repeating it after three months to observe improvements in bone strength and pain relief. I've been using this brand for two years, and I'm very satisfied, especially with my fibromyalgia.
Read More
8.8
Improved recovery process
Important, good quality, non-GMO, and reasonably priced. This vitamin is crucial for life. I take a high amount due to my fibromyalgia, needing elevated levels for recovery. Thank you, iHerb.
8.8
Increased immunity
Vitamin D in high dosage! As a fibromyalgia sufferer, I follow the Coimbra protocol, and this dosage is excellent for improving my immunity, especially in Brazil’s low-sun months.
9.5
Managed sleep apnea
Vitamin D is essential. After taking this high dose with magnesium, zinc, and K2 for six weeks, my levels improved significantly. I plan to reduce my dose now. I noticed my sleep apnea returned when I stopped it, but it resolved quickly when I resumed. This quality product is critical for my fibromyalgia recovery. Thank you, iHerb.
Read More
9.5
Enhanced energy levels
Great choice! I take two capsules monthly, keeping my levels at around 70 ng/mL. It aids in energy, muscle regeneration, and restful sleep. Doctors often overlook that fibromyalgia symptoms can stem from low vitamin D levels.
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