' 
SCIENTIFIC SCORE
Possibly Effective
Based on 14 Researches
7.4
USERS' SCORE
Good
Based on 8 Reviews
8.2
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin D3 (as Cholecalciferol) (From Lanolin)
1,250 mcg (50,000 IU)
6250%
Top Medical Research Studies
9.5
Vitamin D3 ethosomes for psoriasis
Synthesis of vitamin D3 loaded ethosomes gel to cure chronic immune-mediated inflammatory skin disease: physical characterization, in vitro and ex vivo studies.
Strong focus on vitamin D3 effectiveness
We aimed to explore the effectiveness of a special gel infused with vitamin D3, known as an ethosome, in managing psoriasis. This inflammatory skin condition is driven by an overactive immune response, and vitamin D3 plays a crucial role in the growth and development of skin cells called keratinocytes, making it a promising treatment option.
In our research, we created formulas containing different amounts of soya lecithin, propylene glycol, and ethanol to optimize the ethosome gel. After careful testing, we found that these ethosomes had a remarkable drug encapsulation efficiency of 96.25%. They ranged in size from about 148 to 657 nanometers, showing a stable, negatively charged profile that suggests they are safe for use.
Further analyses confirmed that the ethosome gel effectively delivered vitamin D3 through the skin and maintained its stability over six months. The results indicated that an impressive percentage of the medication penetrated the skin barrier, which is essential for its effectiveness in treating psoriasis flare-ups. Our findings suggest that the ethosome formulation enhances the therapeutic potential of vitamin D3, offering a promising avenue for treating patients with psoriasis.
In our research, we created formulas containing different amounts of soya lecithin, propylene glycol, and ethanol to optimize the ethosome gel. After careful testing, we found that these ethosomes had a remarkable drug encapsulation efficiency of 96.25%. They ranged in size from about 148 to 657 nanometers, showing a stable, negatively charged profile that suggests they are safe for use.
Further analyses confirmed that the ethosome gel effectively delivered vitamin D3 through the skin and maintained its stability over six months. The results indicated that an impressive percentage of the medication penetrated the skin barrier, which is essential for its effectiveness in treating psoriasis flare-ups. Our findings suggest that the ethosome formulation enhances the therapeutic potential of vitamin D3, offering a promising avenue for treating patients with psoriasis.
Read More
8
Vitamin D3 ethosomal gel for psoriasis
Synthesis of vitamin D3 loaded ethosomes gel to cure chronic immune-mediated inflammatory skin disease: physical characterization, in vitro and ex vivo studies.
Focuses on vitamin D3 efficacy
We explored the development of ethosomal gels infused with vitamin D3 to target psoriasis, a chronic skin condition driven by immune responses. Vitamin D3 has long been recognized for its vital role in skin health, particularly in promoting the growth and maturation of skin cells known as keratinocytes.
Our research focused on creating a formulation that combines vitamin D3 with soya lecithin, propylene glycol, and ethanol. Through a series of tests, we assessed the size, shape, and encapsulation efficiency of the ethosomes, finding an impressive encapsulation rate of 96.25%.
The optimized ethosomes measured between 148 and 657 nanometers, with a manageable level of aggregation. We confirmed the formulation's safety and stability over six months, making it suitable for patient use. Additionally, our study demonstrated that this delivery system enabled effective permeation of the drug through membrane barriers.
As we delved into the physical characteristics and effectiveness of these gels, we observed that they could provide a novel and practical option for psoriasis sufferers seeking topical treatments.
Our research focused on creating a formulation that combines vitamin D3 with soya lecithin, propylene glycol, and ethanol. Through a series of tests, we assessed the size, shape, and encapsulation efficiency of the ethosomes, finding an impressive encapsulation rate of 96.25%.
The optimized ethosomes measured between 148 and 657 nanometers, with a manageable level of aggregation. We confirmed the formulation's safety and stability over six months, making it suitable for patient use. Additionally, our study demonstrated that this delivery system enabled effective permeation of the drug through membrane barriers.
As we delved into the physical characteristics and effectiveness of these gels, we observed that they could provide a novel and practical option for psoriasis sufferers seeking topical treatments.
Read More
9
Vitamin D's role in psoriasis treatment
Vitamins for the Management of Nail Disease: A Literature Review.
Study highlights vitamin D's efficacy
We investigated the impact of vitamin D treatment on psoriasis, emphasizing its effectiveness for this skin condition. Our focus was on vitamin D as a topical treatment option, particularly in relation to nail psoriasis, a chronic and often challenging ailment.
Through a review of existing studies, we found strong evidence supporting the use of topical vitamin D analogs alongside tazarotene for managing nail psoriasis effectively. This means that for individuals dealing with nail psoriasis, there is a credible therapeutic option that can assist in reducing symptoms and improving overall nail health.
However, when we looked at other nail disorders and broader treatments involving vitamin D, the evidence was limited. We didn’t uncover significant benefits for many conditions when relying solely on vitamins, suggesting that while vitamin D can be helpful, more robust research is needed to ascertain its full potential across various nail disorders.
In conclusion, while there’s promising news for nail psoriasis patients, the journey for solid, proven treatments for other nail conditions could use further exploration.
Through a review of existing studies, we found strong evidence supporting the use of topical vitamin D analogs alongside tazarotene for managing nail psoriasis effectively. This means that for individuals dealing with nail psoriasis, there is a credible therapeutic option that can assist in reducing symptoms and improving overall nail health.
However, when we looked at other nail disorders and broader treatments involving vitamin D, the evidence was limited. We didn’t uncover significant benefits for many conditions when relying solely on vitamins, suggesting that while vitamin D can be helpful, more robust research is needed to ascertain its full potential across various nail disorders.
In conclusion, while there’s promising news for nail psoriasis patients, the journey for solid, proven treatments for other nail conditions could use further exploration.
Read More
Most Useful Reviews
9.5
Effective for psoriasis
Good quality, perfect packaging, and great for skin diseases. I've noticed a significant improvement in my psoriasis and my immunity has also benefited. It has no smell!
Read More
9.5
Helps with symptoms
I use this vitamin D for my immune disease (psoriasis) and it helps a lot. Recommended by my doctor, I’ve been happy with the quality and price.
Read More
8.8
Improved flare-ups
I started taking this Vitamin D-3 as it received positive feedback from other psoriasis patients. It has effectively reduced my flare-ups to a manageable level.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 14 Researches
7.4
- All Researches
9.5
Vitamin D3 ethosomes for psoriasis
Synthesis of vitamin D3 loaded ethosomes gel to cure chronic immune-mediated inflammatory skin disease: physical characterization, in vitro and ex vivo studies.
Strong focus on vitamin D3 effectiveness
We aimed to explore the effectiveness of a special gel infused with vitamin D3, known as an ethosome, in managing psoriasis. This inflammatory skin condition is driven by an overactive immune response, and vitamin D3 plays a crucial role in the growth and development of skin cells called keratinocytes, making it a promising treatment option.
In our research, we created formulas containing different amounts of soya lecithin, propylene glycol, and ethanol to optimize the ethosome gel. After careful testing, we found that these ethosomes had a remarkable drug encapsulation efficiency of 96.25%. They ranged in size from about 148 to 657 nanometers, showing a stable, negatively charged profile that suggests they are safe for use.
Further analyses confirmed that the ethosome gel effectively delivered vitamin D3 through the skin and maintained its stability over six months. The results indicated that an impressive percentage of the medication penetrated the skin barrier, which is essential for its effectiveness in treating psoriasis flare-ups. Our findings suggest that the ethosome formulation enhances the therapeutic potential of vitamin D3, offering a promising avenue for treating patients with psoriasis.
In our research, we created formulas containing different amounts of soya lecithin, propylene glycol, and ethanol to optimize the ethosome gel. After careful testing, we found that these ethosomes had a remarkable drug encapsulation efficiency of 96.25%. They ranged in size from about 148 to 657 nanometers, showing a stable, negatively charged profile that suggests they are safe for use.
Further analyses confirmed that the ethosome gel effectively delivered vitamin D3 through the skin and maintained its stability over six months. The results indicated that an impressive percentage of the medication penetrated the skin barrier, which is essential for its effectiveness in treating psoriasis flare-ups. Our findings suggest that the ethosome formulation enhances the therapeutic potential of vitamin D3, offering a promising avenue for treating patients with psoriasis.
Read More
9.5
Vitamin D3's role in psoriasis
Impact of topical emollient, steroids alone or combined with calcipotriol, on the immune infiltrate and clinical outcome in psoriasis.
Combined treatment effects evaluated
We conducted a study to better understand how topical treatments, particularly those involving vitamin D3, affect psoriasis. In our investigation, we focused on a group of 30 psoriasis patients, using a double-blind, randomized approach. This means neither the patients nor the researchers knew who received which treatment, ensuring an unbiased evaluation of their effects.
The treatments explored included a combination of Calcipotriol (a vitamin D3 analogue) and Betamethasone (a steroid), as well as Betamethasone alone and Clobetasol Propionate ointment. Through the analysis of skin biopsies before and after four weeks of treatment, we observed changes in skin inflammation, cellular infiltrate, and patients’ clinical scores for psoriasis severity.
While we noted that all treatments helped reduce skin thickness and improved patient scores, the greatest impact was seen with the combination of Calcipotriol and Betamethasone. This specific treatment effectively diminished the number of harmful immune cells that contribute to psoriasis flare-ups. However, the isolated effect of vitamin D3 alone wasn’t clearly established, as the most significant outcomes were tied to its use in combination with steroids.
Ultimately, our findings suggest that while vitamin D3 plays a role in psoriasis treatment, its benefits are most pronounced when paired with corticosteroids. This combination could potentially lead to enhanced long-term management of the disease, although the specific contribution of vitamin D3 alone remains uncertain.
The treatments explored included a combination of Calcipotriol (a vitamin D3 analogue) and Betamethasone (a steroid), as well as Betamethasone alone and Clobetasol Propionate ointment. Through the analysis of skin biopsies before and after four weeks of treatment, we observed changes in skin inflammation, cellular infiltrate, and patients’ clinical scores for psoriasis severity.
While we noted that all treatments helped reduce skin thickness and improved patient scores, the greatest impact was seen with the combination of Calcipotriol and Betamethasone. This specific treatment effectively diminished the number of harmful immune cells that contribute to psoriasis flare-ups. However, the isolated effect of vitamin D3 alone wasn’t clearly established, as the most significant outcomes were tied to its use in combination with steroids.
Ultimately, our findings suggest that while vitamin D3 plays a role in psoriasis treatment, its benefits are most pronounced when paired with corticosteroids. This combination could potentially lead to enhanced long-term management of the disease, although the specific contribution of vitamin D3 alone remains uncertain.
Read More
9
Vitamin D's role in psoriasis treatment
Vitamins for the Management of Nail Disease: A Literature Review.
Study highlights vitamin D's efficacy
We investigated the impact of vitamin D treatment on psoriasis, emphasizing its effectiveness for this skin condition. Our focus was on vitamin D as a topical treatment option, particularly in relation to nail psoriasis, a chronic and often challenging ailment.
Through a review of existing studies, we found strong evidence supporting the use of topical vitamin D analogs alongside tazarotene for managing nail psoriasis effectively. This means that for individuals dealing with nail psoriasis, there is a credible therapeutic option that can assist in reducing symptoms and improving overall nail health.
However, when we looked at other nail disorders and broader treatments involving vitamin D, the evidence was limited. We didn’t uncover significant benefits for many conditions when relying solely on vitamins, suggesting that while vitamin D can be helpful, more robust research is needed to ascertain its full potential across various nail disorders.
In conclusion, while there’s promising news for nail psoriasis patients, the journey for solid, proven treatments for other nail conditions could use further exploration.
Through a review of existing studies, we found strong evidence supporting the use of topical vitamin D analogs alongside tazarotene for managing nail psoriasis effectively. This means that for individuals dealing with nail psoriasis, there is a credible therapeutic option that can assist in reducing symptoms and improving overall nail health.
However, when we looked at other nail disorders and broader treatments involving vitamin D, the evidence was limited. We didn’t uncover significant benefits for many conditions when relying solely on vitamins, suggesting that while vitamin D can be helpful, more robust research is needed to ascertain its full potential across various nail disorders.
In conclusion, while there’s promising news for nail psoriasis patients, the journey for solid, proven treatments for other nail conditions could use further exploration.
Read More
9
Calcipotriol more effective than calcitriol
Comparative evaluation of efficacy and safety of calcipotriol versus calcitriol ointment, both in combination with narrow-band ultraviolet B phototherapy in the treatment of stable plaque psoriasis.
Study confirms vitamin D3's role
We explored the effectiveness of two vitamin D analogues, calcipotriol and calcitriol, in treating stable plaque psoriasis when combined with narrow-band ultraviolet B (NBUVB) phototherapy. Our study involved thirty patients who were treated for 12 weeks, applying calcitriol ointment to one side and calcipotriol ointment to the other.
Throughout the trial, we observed significant improvements in skin conditions such as erythema, scaling, and overall plaque thickness with both treatments. Remarkably, those using calcipotriol showed quicker clearance of plaques and experienced fewer relapses compared to those using calcitriol.
Both treatments were found to be safe and well-tolerated, making them cosmetically appealing options. However, calcipotriol not only demonstrated a rapid onset of action but also maintained its efficacy more consistently over the treatment period.
Throughout the trial, we observed significant improvements in skin conditions such as erythema, scaling, and overall plaque thickness with both treatments. Remarkably, those using calcipotriol showed quicker clearance of plaques and experienced fewer relapses compared to those using calcitriol.
Both treatments were found to be safe and well-tolerated, making them cosmetically appealing options. However, calcipotriol not only demonstrated a rapid onset of action but also maintained its efficacy more consistently over the treatment period.
Read More
8
Vitamin D3 ethosomal gel for psoriasis
Synthesis of vitamin D3 loaded ethosomes gel to cure chronic immune-mediated inflammatory skin disease: physical characterization, in vitro and ex vivo studies.
Focuses on vitamin D3 efficacy
We explored the development of ethosomal gels infused with vitamin D3 to target psoriasis, a chronic skin condition driven by immune responses. Vitamin D3 has long been recognized for its vital role in skin health, particularly in promoting the growth and maturation of skin cells known as keratinocytes.
Our research focused on creating a formulation that combines vitamin D3 with soya lecithin, propylene glycol, and ethanol. Through a series of tests, we assessed the size, shape, and encapsulation efficiency of the ethosomes, finding an impressive encapsulation rate of 96.25%.
The optimized ethosomes measured between 148 and 657 nanometers, with a manageable level of aggregation. We confirmed the formulation's safety and stability over six months, making it suitable for patient use. Additionally, our study demonstrated that this delivery system enabled effective permeation of the drug through membrane barriers.
As we delved into the physical characteristics and effectiveness of these gels, we observed that they could provide a novel and practical option for psoriasis sufferers seeking topical treatments.
Our research focused on creating a formulation that combines vitamin D3 with soya lecithin, propylene glycol, and ethanol. Through a series of tests, we assessed the size, shape, and encapsulation efficiency of the ethosomes, finding an impressive encapsulation rate of 96.25%.
The optimized ethosomes measured between 148 and 657 nanometers, with a manageable level of aggregation. We confirmed the formulation's safety and stability over six months, making it suitable for patient use. Additionally, our study demonstrated that this delivery system enabled effective permeation of the drug through membrane barriers.
As we delved into the physical characteristics and effectiveness of these gels, we observed that they could provide a novel and practical option for psoriasis sufferers seeking topical treatments.
Read More
User Reviews
USERS' SCORE
Good
Based on 8 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Effective for psoriasis
Good quality, perfect packaging, and great for skin diseases. I've noticed a significant improvement in my psoriasis and my immunity has also benefited. It has no smell!
9.5
Helps with symptoms
I use this vitamin D for my immune disease (psoriasis) and it helps a lot. Recommended by my doctor, I’ve been happy with the quality and price.
8.8
Improved flare-ups
I started taking this Vitamin D-3 as it received positive feedback from other psoriasis patients. It has effectively reduced my flare-ups to a manageable level.
8.8
Better improvement
I've been taking this vitamin for two weeks and have noticed better improvement in my psoriasis. It has no taste, and I'm taking it alongside tudca for absorption.
8.8
Reliable quality
This product works almost immediately to reduce scaling of my psoriasis. The quality is reliable, ingredients are halal, and it’s small enough to swallow.
