We conducted a nested case-control study within a large cohort to understand how levels of taurine, S-adenosylmethionine (SAM), and cysteine in our blood are related to cancer risk, particularly among Chinese adults. Our analysis included 1,391 cancer cases matched with 1,391 controls, providing a robust framework for our findings.
Our results showed that higher levels of taurine in the blood could reduce overall cancer risk, particularly for digestive cancers. This is an exciting discovery as it suggests that taurine might play a protective role. On the contrary, elevated levels of SAM appeared linked to an increased risk of digestive cancers.
Using advanced statistical models, we identified complex interactions among taurine, SAM, and cysteine. Notably, we observed a significant overall negative association between the combination of these amino acids and cancer risk, highlighting the intricate balance these compounds maintain in our metabolism.
Overall, while taurine seems to confer some protective benefits, the specific metabolic relationships and their implications for treatment and prevention strategies need further exploration. Our findings could pave the way for new approaches in cancer prevention.
Read More
8
Taurine's potential in CRC diagnosis
Systematic Review and Meta-Analysis: Taurine and Its Association With Colorectal Carcinoma.
We conducted an in-depth exploration of taurine's relationship with colorectal cancer (CRC) through a systematic review of existing studies. Our investigation looked at various research studies to gather insights into how taurine levels relate to cancer.
We discovered a significant association between higher taurine levels and the presence of CRC. Specifically, findings indicated that taurine concentrations were elevated in CRC patient samples, particularly in blood. More importantly, taurine showed potential as a diagnostic marker, which could help to distinguish between benign and malignant conditions in patients at differing stages of cancer.
Despite these promising results, it’s worth noting that there was considerable variability in some outcomes across different studies. This highlights the need for further research to clarify taurine’s role, but our analysis suggests an overall trend indicating that increased taurine may be linked to greater odds of developing CRC.
As we continue to look into the connection between taurine and colorectal cancer, it opens up exciting possibilities for future diagnostics and treatments that leverage our understanding of metabolic changes associated with this disease.
Read More
7
Taurine's mixed effects on cancer
Serum taurine affects lung cancer progression by regulating tumor immune escape mediated by the immune microenvironment.
We set out to understand the role of taurine, a naturally occurring acid in our bodies, in lung cancer development. Previous findings indicated that elevated taurine levels were present in lung cancer patients, prompting us to investigate its impact more closely.
Through our research involving mouse models, RNA sequencing, and stable transfection techniques, we observed significant insights into how taurine may affect lung cancer progression. We analyzed tissue samples from non-small cell lung cancer patients to enhance our findings and help clarify the relationship between taurine and cancer.
Our results suggest that while taurine may be a potential biomarker, its effects can differ based on the patient's age and immune status. For younger lung cancer patients, taurine-rich drinks could potentially pose risks, while older or immune-deficient patients may benefit from such treatments. Overall, the specific mechanisms of taurine’s impact on cancer progress warrant further exploration and suggest careful consideration for future treatments.
Read More
Most Useful Reviews
7.5
Effective for metastasis
5 people found this helpful
Very good! I know it is effective for cancer, and I use it to help my husband's peritoneal cancer metastasis. Additionally, I take it to improve my bad cholesterol. I believe it benefits both conditions. I would recommend it, but it can cause significant tiredness.
Read More
6
May improve eyesight
288 people found this helpful
This supplement was initially for my cat with cancer. After he passed, I began using it for my 97-year-old mother. Though it's hard to gauge its effects conclusively, I've noticed a slight improvement in my close vision at 71. While the change isn't remarkable, I feel it has helped me read better and may prevent further decline. I plan to continue monitoring its benefits.
Read More
9
Prevents cancer development
Taurine is a very strong antioxidant that effectively prevents the development of cancer and reduces blood glucose levels.
We investigated how taurine, an important amino acid, influences the effectiveness of 5-fluorouracil (5-FU), a common chemotherapy drug used to treat colon cancer. In our study, we chemically induced cancer in rats and then treated them with taurine for eight days while observing their colon tissues.
Our findings revealed concerning trends among the different treatment groups. While the control group showed 80% of adenocarcinoma cases, those who received only 5-FU had 70%, and those on taurine alone reported 50%. Remarkably, no adenocarcinoma was found in the group treated with both 5-FU and taurine, suggesting a powerful synergy.
Additionally, we noted that while inflammatory responses and certain gene expressions remained similar across the cancer-induced groups, the expression of a critical protein (APC/β-catenin) increased in the combination group. This suggests that taking taurine might help harness the strengths of 5-FU while lowering potential adverse effects.
Despite some encouraging evidence, we did not observe any significant improvement in inflammation or gene markers typically associated with cancer. However, using taurine appears to normalize some concerning results linked directly to treatment with 5-FU. Overall, the combination shows potential for enhancing treatment outcomes in colon cancer.
Read More
8
Taurine's protective role in cancer
Interplay of serum taurine, S-adenosylmethionine, and cysteine levels in cancer risk: a prospective study.
We conducted a nested case-control study within a large cohort to understand how levels of taurine, S-adenosylmethionine (SAM), and cysteine in our blood are related to cancer risk, particularly among Chinese adults. Our analysis included 1,391 cancer cases matched with 1,391 controls, providing a robust framework for our findings.
Our results showed that higher levels of taurine in the blood could reduce overall cancer risk, particularly for digestive cancers. This is an exciting discovery as it suggests that taurine might play a protective role. On the contrary, elevated levels of SAM appeared linked to an increased risk of digestive cancers.
Using advanced statistical models, we identified complex interactions among taurine, SAM, and cysteine. Notably, we observed a significant overall negative association between the combination of these amino acids and cancer risk, highlighting the intricate balance these compounds maintain in our metabolism.
Overall, while taurine seems to confer some protective benefits, the specific metabolic relationships and their implications for treatment and prevention strategies need further exploration. Our findings could pave the way for new approaches in cancer prevention.
Read More
8
Taurine metabolism impact on cancer
Taurine Synthesis by 2-Aminoethanethiol Dioxygenase as a Vulnerable Metabolic Alteration in Pancreatic Cancer.
We conducted a thorough investigation into how taurine, an amino acid, relates to pancreatic ductal adenocarcinoma (PDAC). Our study involved analyzing 54 pairs of tumor and matching normal pancreatic tissues using advanced metabolomics. We found that taurine levels in PDAC tissues were 2.51 times higher compared to normal tissues.
To confirm these findings, we used immunohistochemistry (IHC) on additional samples, which demonstrated a similar increase in taurine. Through bioinformatics, we identified 2-aminoethanethiol dioxygenase (ADO) as a crucial gene influencing taurine metabolism. Further IHC analysis confirmed elevated levels of ADO in PDAC tissues, indicating a potential link between ADO and tumor behavior.
Excitingly, we observed that the ADO-Taurine axis was associated with key clinical outcomes like disease-free survival and cancer recurrence. In experiments where we knocked down ADO, we noticed reduced cancer cell growth, suggesting that taurine metabolism could impact tumor progression. Overall, our findings point to elevated taurine synthesis in PDAC driven by ADO, presenting a promising target for future cancer therapies and a possible prognostic marker for patients.
Read More
8
Taurine's potential in CRC diagnosis
Systematic Review and Meta-Analysis: Taurine and Its Association With Colorectal Carcinoma.
We conducted an in-depth exploration of taurine's relationship with colorectal cancer (CRC) through a systematic review of existing studies. Our investigation looked at various research studies to gather insights into how taurine levels relate to cancer.
We discovered a significant association between higher taurine levels and the presence of CRC. Specifically, findings indicated that taurine concentrations were elevated in CRC patient samples, particularly in blood. More importantly, taurine showed potential as a diagnostic marker, which could help to distinguish between benign and malignant conditions in patients at differing stages of cancer.
Despite these promising results, it’s worth noting that there was considerable variability in some outcomes across different studies. This highlights the need for further research to clarify taurine’s role, but our analysis suggests an overall trend indicating that increased taurine may be linked to greater odds of developing CRC.
As we continue to look into the connection between taurine and colorectal cancer, it opens up exciting possibilities for future diagnostics and treatments that leverage our understanding of metabolic changes associated with this disease.
Read More
8
Taurine mitigates irinotecan muscle damage
Taurine Protects Irinotecan-induced Muscle Dysfunction by Modulating Oxidative Stress and Endoplasmic Reticulum Stress in Human Skeletal Muscle Cells.
We explored the effects of taurine, a conditionally essential amino acid known for its antioxidant properties, on muscle dysfunction caused by irinotecan, a common chemotherapy drug for metastatic colorectal cancer. Our aim was to determine whether taurine could mitigate the negative impact of irinotecan on human skeletal muscle cells (HSkMCs).
We conducted experiments by treating these muscle cells with irinotecan while some were pre-treated with taurine. We carefully monitored how these treatments affected cell viability, toxicity, and the ability of the cells to differentiate into muscle fibers. Our findings revealed some encouraging results: taurine significantly improved cell viability, reduced toxicity, and preserved the cells' capability to differentiate, which had been compromised by irinotecan.
Remarkably, taurine also seemed to help counteract the oxidative stress and endoplasmic reticulum stress triggered by irinotecan. This suggests that taurine might be a valuable ally in enhancing muscle health for patients undergoing cancer treatment, potentially easing symptoms of cancer cachexia, which often arises due to chemotherapy-induced muscle dysfunction.
Very good! I know it is effective for cancer, and I use it to help my husband's peritoneal cancer metastasis. Additionally, I take it to improve my bad cholesterol. I believe it benefits both conditions. I would recommend it, but it can cause significant tiredness.
Read More
6
May improve eyesight
288 people found this helpful
This supplement was initially for my cat with cancer. After he passed, I began using it for my 97-year-old mother. Though it's hard to gauge its effects conclusively, I've noticed a slight improvement in my close vision at 71. While the change isn't remarkable, I feel it has helped me read better and may prevent further decline. I plan to continue monitoring its benefits.
Read More
9
Prevents cancer development
Taurine is a very strong antioxidant that effectively prevents the development of cancer and reduces blood glucose levels.
Read More
9
Supports metabolism and health
Taurine, an amino acid, is a potent antioxidant that prevents cancer development and is involved in retinal cell formation and renewal. It helps with metabolism, nutrient transport, strengthens the nervous system, calms nerves, and boosts blood flow. Now Foods offers superb quality, and the dosage is commendable.
Read More
7.5
Cardiovascular benefits noted
Taurine is a natural amino acid found in various tissues and organs. It shows promise in treating heart and vascular diseases, serves as a powerful antioxidant, reduces cancer risk, lowers blood sugar levels, normalises blood pressure, and prevents atherosclerosis. It regulates crucial electrolytes for heart function and promotes blood flow and metabolic processes.
Cancer is a complex group of diseases characterized by uncontrolled growth and spread of abnormal cells in the body. These cells can form tumors, invade nearby tissues, and metastasize to other parts of the body via the bloodstream or lymphatic system. While cancer can affect nearly any part of the body, it is classified into various types, including carcinomas, sarcomas, leukemia, and lymphomas, each originating from different types of cells. Risk factors for developing cancer can include genetic predisposition, lifestyle choices such as smoking and diet, environmental exposures, and certain infections.
Diagnosis typically involves medical imaging, biopsies, and a thorough review of personal and family health histories. Treatment options vary widely depending on the type and stage of cancer and may include surgery, chemotherapy, radiation therapy, immunotherapy, and targeted therapies. Early detection is crucial and can significantly improve treatment outcomes, leading to better survival rates. As awareness and research continue to advance, new methods for prevention, detection, and treatment of cancer are consistently being developed, offering hope to those affected by this challenging disease.
L-Taurine is a sulfonic acid and an amino acid often categorized as a conditionally essential amino acid due to its important roles in various bodily functions. Unlike most amino acids, L-Taurine is not used to synthesize proteins but is critical for several physiological processes, including bile salt formation, osmoregulation, and antioxidant defense. It’s naturally found in high concentrations in the brain, muscles, heart, and blood, playing a vital role in cardiovascular health and the maintenance of neurological function.
L-Taurine is often included in dietary supplements and energy drinks due to its potential benefits, such as enhancing exercise performance, improving recovery, and supporting overall energy levels. While the body can produce taurine from other amino acids like cysteine, some people may choose to supplement with it, particularly athletes or those seeking additional health benefits. As always, it's important to consult with a healthcare provider before starting any new supplement regimen to ensure safety and appropriateness for your individual health needs.
Based on user reviews, the timeframe for seeing results from this supplement in relation to cancer management can vary. Many users suggest that while the supplement is recognized for its potent antioxidant properties and role in cancer prevention, the effectiveness can greatly depend on individual factors and the specific condition being treated. For instance, one user reported using the supplement for her husband's peritoneal cancer metastasis, indicating personal belief in its effectiveness. However, no specific time frame is provided for when to expect noticeable results Read Review.
Additionally, another user mentioned that the frequent stock shortages of this supplement might be indicative of its perceived effectiveness among cancer patients, further suggesting a level of trust in its benefits despite the absence of a defined timeline Read Review. Overall, it seems advisable to consult with a healthcare professional for personalized guidance, as individual responses can vary significantly.
The role of taurine, an amino acid, in cancer research presents a complex yet promising narrative. Several studies indicate that taurine may exhibit protective benefits against certain types of cancers, particularly digestive cancers. A nested case-control study revealed that higher serum levels of taurine are correlated with a reduced overall cancer risk, particularly in digestive systems [1]. Moreover, findings in the context of colorectal cancer (CRC) suggest that elevated taurine levels might be indicative of CRC, proposing its potential role as a diagnostic marker [3].
Furthermore, research has explored taurine's potential therapeutic benefits in various cancer treatments. For instance, combining taurine with chemotherapy has shown synergistic effects, enhancing the efficacy of 5-fluorouracil in colon cancer while mitigating some adverse effects [7]. Other studies have pointed to taurine's involvement in metabolic pathways associated with pancreatic cancer and its potential as a prognostic marker [2]. Overall, while taurine shows considerable promise based on current research, its dual roles in cancer promotion and inhibition highlight the need for a nuanced understanding and further exploration in clinical applications.
Based on user reviews, many individuals report experiencing a range of improvements in their symptoms after using taurine as a supplement. Several users emphasize its potent antioxidant properties that not only help prevent cancer development but also contribute to lowering blood glucose levels. For instance, one reviewer acknowledges that taurine is effective for cancer and is also beneficial in managing cholesterol levels, indicating a multifaceted positive impact on health Read Review. Additionally, users have noted its benefits in metabolic processes and blood flow, which can lead to overall better health outcomes Read Review.
Moreover, the frequency of stock shortages for this supplement suggests a high level of trust in its efficacy among users Read Review. Another reviewer indicates that taurine can aid in the recovery of retinal cells, showcasing its diverse health applications. However, it's essential to remember that individual results can vary widely, and consulting with a healthcare professional is advisable for personalized advice Read Review.
Based on user reviews, many individuals have reported benefits from combining taurine with other supplements while managing cancer. One user specifically highlighted using taurine alongside their husband's cancer treatment, not only emphasizing its effectiveness for peritoneal cancer metastasis but also noting its positive effects on cholesterol levels, suggesting a versatile application of the supplement in cancer care Read Review. Additionally, other reviewers point out taurine's potent antioxidant properties that effectively help in preventing cancer and reducing blood glucose levels, aligning well with various health improvement goals Read ReviewRead Review.
Moreover, users also express confidence in taurine's recommendation for cancer patients, further suggesting its perceived efficacy, which may contribute to frequent stock shortages Read Review. The broad recognition of taurine as both a cancer preventative and a supplement that supports metabolic processes indicates users are exploring its combination with other health strategies to address multiple conditions effectively Read Review. However, as individual results can vary, it's advisable for users to consult with healthcare professionals when considering supplement combinations for cancer management.
Based on user reviews, L-Taurine appears to be considered a promising supplement for those looking to support cancer treatment, although specific dosage guidance is not mentioned. Several users report its potent antioxidant properties and its effectiveness in helping to prevent cancer development and support overall health during cancer treatment. One user noted its use for peritoneal cancer metastasis and mentioned that it helped their husband, along with other health benefits like improving cholesterol levels Read Review.
Moreover, it's noted that the supplement is often recommended for cancer patients, with users feeling that its effectiveness contributes to frequent stock shortages Read Review. While many users advocate for L-Taurine's beneficial properties in cancer prevention and support, the reviews lack specific guidance on the ideal dosage required to achieve these effects, indicating that individual needs may vary and suggesting a conversation with a healthcare provider for personalized recommendations.
7.5
Effective for metastasis
5 people found this helpful
Very good! I know it is effective for cancer, and I use it to help my husband's peritoneal cancer metastasis. Additionally, I take it to improve my bad cholesterol. I believe it benefits both conditions. I would recommend it, but it can cause significant tiredness.
7.5
Recommended for cancer patients
This supplement was recommended for cancer patients. I believe its frequent stock shortages are due to many users feeling it is effective.
9
Supports metabolism and health
Taurine, an amino acid, is a potent antioxidant that prevents cancer development and is involved in retinal cell formation and renewal. It helps with metabolism, nutrient transport, strengthens the nervous system, calms nerves, and boosts blood flow. Now Foods offers superb quality, and the dosage is commendable.
9
Strong antioxidant benefits
2 people found this helpful
This is a very strong antioxidant. It not only prevents the development of cancer, but also lowers blood glucose levels. Moreover, it assists in forming the retina of the eyes and aids in its recovery after injuries.
9
Prevents cancer development
Taurine is a very strong antioxidant that effectively prevents the development of cancer and reduces blood glucose levels.
8
Taurine's protective role in cancer
Interplay of serum taurine, S-adenosylmethionine, and cysteine levels in cancer risk: a prospective study.
We conducted a nested case-control study within a large cohort to understand how levels of taurine, S-adenosylmethionine (SAM), and cysteine in our blood are related to cancer risk, particularly among Chinese adults. Our analysis included 1,391 cancer cases matched with 1,391 controls, providing a robust framework for our findings.
Our results showed that higher levels of taurine in the blood could reduce overall cancer risk, particularly for digestive cancers. This is an exciting discovery as it suggests that taurine might play a protective role. On the contrary, elevated levels of SAM appeared linked to an increased risk of digestive cancers.
Using advanced statistical models, we identified complex interactions among taurine, SAM, and cysteine. Notably, we observed a significant overall negative association between the combination of these amino acids and cancer risk, highlighting the intricate balance these compounds maintain in our metabolism.
Overall, while taurine seems to confer some protective benefits, the specific metabolic relationships and their implications for treatment and prevention strategies need further exploration. Our findings could pave the way for new approaches in cancer prevention.
8
Taurine's potential in CRC diagnosis
Systematic Review and Meta-Analysis: Taurine and Its Association With Colorectal Carcinoma.
We conducted an in-depth exploration of taurine's relationship with colorectal cancer (CRC) through a systematic review of existing studies. Our investigation looked at various research studies to gather insights into how taurine levels relate to cancer.
We discovered a significant association between higher taurine levels and the presence of CRC. Specifically, findings indicated that taurine concentrations were elevated in CRC patient samples, particularly in blood. More importantly, taurine showed potential as a diagnostic marker, which could help to distinguish between benign and malignant conditions in patients at differing stages of cancer.
Despite these promising results, it’s worth noting that there was considerable variability in some outcomes across different studies. This highlights the need for further research to clarify taurine’s role, but our analysis suggests an overall trend indicating that increased taurine may be linked to greater odds of developing CRC.
As we continue to look into the connection between taurine and colorectal cancer, it opens up exciting possibilities for future diagnostics and treatments that leverage our understanding of metabolic changes associated with this disease.
9.5
Taurine enhances 5-FU effectiveness
Synergistic Enhancement of 5-Fluorouracil Chemotherapeutic Efficacy by Taurine in Colon Cancer Rat Model.
We investigated how taurine, an important amino acid, influences the effectiveness of 5-fluorouracil (5-FU), a common chemotherapy drug used to treat colon cancer. In our study, we chemically induced cancer in rats and then treated them with taurine for eight days while observing their colon tissues.
Our findings revealed concerning trends among the different treatment groups. While the control group showed 80% of adenocarcinoma cases, those who received only 5-FU had 70%, and those on taurine alone reported 50%. Remarkably, no adenocarcinoma was found in the group treated with both 5-FU and taurine, suggesting a powerful synergy.
Additionally, we noted that while inflammatory responses and certain gene expressions remained similar across the cancer-induced groups, the expression of a critical protein (APC/β-catenin) increased in the combination group. This suggests that taking taurine might help harness the strengths of 5-FU while lowering potential adverse effects.
Despite some encouraging evidence, we did not observe any significant improvement in inflammation or gene markers typically associated with cancer. However, using taurine appears to normalize some concerning results linked directly to treatment with 5-FU. Overall, the combination shows potential for enhancing treatment outcomes in colon cancer.
8
Taurine metabolism impact on cancer
Taurine Synthesis by 2-Aminoethanethiol Dioxygenase as a Vulnerable Metabolic Alteration in Pancreatic Cancer.
We conducted a thorough investigation into how taurine, an amino acid, relates to pancreatic ductal adenocarcinoma (PDAC). Our study involved analyzing 54 pairs of tumor and matching normal pancreatic tissues using advanced metabolomics. We found that taurine levels in PDAC tissues were 2.51 times higher compared to normal tissues.
To confirm these findings, we used immunohistochemistry (IHC) on additional samples, which demonstrated a similar increase in taurine. Through bioinformatics, we identified 2-aminoethanethiol dioxygenase (ADO) as a crucial gene influencing taurine metabolism. Further IHC analysis confirmed elevated levels of ADO in PDAC tissues, indicating a potential link between ADO and tumor behavior.
Excitingly, we observed that the ADO-Taurine axis was associated with key clinical outcomes like disease-free survival and cancer recurrence. In experiments where we knocked down ADO, we noticed reduced cancer cell growth, suggesting that taurine metabolism could impact tumor progression. Overall, our findings point to elevated taurine synthesis in PDAC driven by ADO, presenting a promising target for future cancer therapies and a possible prognostic marker for patients.
References
Liu C, Liu T, Wei Y, Shi J, Deng L, et al. Interplay of serum taurine, S-adenosylmethionine, and cysteine levels in cancer risk: a prospective study. Front Pharmacol. 2024;15:1507125. doi:10.3389/fphar.2024.1507125
Nam H, Lee W, Lee YJ, Kim JM, Jung KH, et al. Taurine Synthesis by 2-Aminoethanethiol Dioxygenase as a Vulnerable Metabolic Alteration in Pancreatic Cancer. Biomol Ther (Seoul). 2025;33:143. doi:10.4062/biomolther.2024.086
Sinha A, Griffith L, Acharjee A. Systematic Review and Meta-Analysis: Taurine and Its Association With Colorectal Carcinoma. Cancer Med. 2024;13:e70424. doi:10.1002/cam4.70424
Chen CI, Chen YC, Kao YK, Chen CH, Yang PW, et al. Taurine Protects Irinotecan-induced Muscle Dysfunction by Modulating Oxidative Stress and Endoplasmic Reticulum Stress in Human Skeletal Muscle Cells. Anticancer Res. 2024;44:5371. doi:10.21873/anticanres.17364
Das J, Singh TA, Lalruatsangi R, Sil PC. Synthesis of nanohybrid consisting of taurine derived carbon dots and nanoceria for anticancer applications. Toxicol Rep. 2024;13:101794. doi:10.1016/j.toxrep.2024.101794
Lawore DC, Jena S, Berard AR, Birse K, Lamont A, et al. Computational Microbiome Pharmacology Analysis Elucidates the Anti-Cancer Potential of Vaginal Microbes and Metabolites. bioRxiv. 2024. doi:10.1101/2024.10.10.616351
Jornada DH, Boreski D, Chiba DE, Ligeiro D, Luz MAM, et al. Synergistic Enhancement of 5-Fluorouracil Chemotherapeutic Efficacy by Taurine in Colon Cancer Rat Model. Nutrients. 2024;16. doi:10.3390/nu16183047
Shentu J, Su X, Yu Y, Duan S. Unveiling the role of taurine and SLC6A6 in tumor immune evasion: Implications for gastric cancer therapy. Int J Biochem Cell Biol. 2024;176:106661. doi:10.1016/j.biocel.2024.106661
Liang TL, Pan HD, Yan PY, Mi JN, Liu XC, et al. Serum taurine affects lung cancer progression by regulating tumor immune escape mediated by the immune microenvironment. J Adv Res. 2024. doi:10.1016/j.jare.2024.09.005