' 
![]()
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
USERS' SCORE
Good
Based on 2 Reviews
8.7
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin E (as d-alpha Tocopheryl Acetate)
268 mg
1787%
Top Medical Research Studies
7
Vitamin E benefits menopause mood disorders
Ameliorative effect of α-tocopherol and tocotrienol-rich palm oil extract on menopause-associated mood disorder in ovariectomized mice.
Investigates vitamin E and anxiety
We explored the effects of vitamin E on anxiety and depression, particularly in the context of menopause-related mood disorders. To conduct this research, we studied ovariectomized mice—an animal model representing estrogen deficiency.
Our findings indicated that ovariectomized mice exhibited behaviors linked to depression and anxiety. Notably, these mice had higher levels of corticosterone, a hormone that signals stress, compared to a control group. We observed that administering α-tocopherol (a form of vitamin E) and tocotrienol-rich palm oil extract significantly reduced these mood disturbances over a two-week period.
While both treatments helped alleviate anxiety and depressive behaviors, tocotrienol-rich palm oil extract showed a more pronounced effect, particularly in mice under chronic stress. Additionally, both forms of vitamin E were effective in lowering elevated corticosterone levels, suggesting that they may help modulate the body’s stress response.
Overall, our research supports the potential of vitamin E as a promising treatment for mood disorders associated with menopause, highlighting its role in improving psychological well-being.
Our findings indicated that ovariectomized mice exhibited behaviors linked to depression and anxiety. Notably, these mice had higher levels of corticosterone, a hormone that signals stress, compared to a control group. We observed that administering α-tocopherol (a form of vitamin E) and tocotrienol-rich palm oil extract significantly reduced these mood disturbances over a two-week period.
While both treatments helped alleviate anxiety and depressive behaviors, tocotrienol-rich palm oil extract showed a more pronounced effect, particularly in mice under chronic stress. Additionally, both forms of vitamin E were effective in lowering elevated corticosterone levels, suggesting that they may help modulate the body’s stress response.
Overall, our research supports the potential of vitamin E as a promising treatment for mood disorders associated with menopause, highlighting its role in improving psychological well-being.
Read More
8
Vitamin E alleviates anxiety symptoms
Coenzyme Q10 and vitamin E alleviate heat stress-induced mood disturbances in male mice: Modulation of inflammatory pathways and the HPA axis.
Combination treatment complicates effects
In our exploration of how vitamin E affects anxiety, we studied male mice that were exposed to heat stress, which is known to trigger symptoms of anxiety and depression. We divided the mice into five groups: a control group, a heat stress group, and three treatment groups that received either vitamin E, coenzyme Q10, or a combination of both.
Over the course of 14 days, the heat-stressed mice underwent daily treatments, and we conducted various behavioral tests to measure signs of anxiety and depression. Remarkably, we discovered that both vitamin E alone and in combination with coenzyme Q10 provided significant relief from anxiety-related behaviors.
This was evident as we observed lowered anxiety levels and decreased despair behaviors in the treated groups compared to those that only experienced heat stress. Additionally, we noted a reduction in serum levels of corticosterone, a hormone associated with stress, which further supports the beneficial effects of vitamin E.
By modulating inflammatory pathways and influencing brain function, vitamin E, along with coenzyme Q10, appears to help counteract the negative emotional impacts of environmental stressors like heat.
Over the course of 14 days, the heat-stressed mice underwent daily treatments, and we conducted various behavioral tests to measure signs of anxiety and depression. Remarkably, we discovered that both vitamin E alone and in combination with coenzyme Q10 provided significant relief from anxiety-related behaviors.
This was evident as we observed lowered anxiety levels and decreased despair behaviors in the treated groups compared to those that only experienced heat stress. Additionally, we noted a reduction in serum levels of corticosterone, a hormone associated with stress, which further supports the beneficial effects of vitamin E.
By modulating inflammatory pathways and influencing brain function, vitamin E, along with coenzyme Q10, appears to help counteract the negative emotional impacts of environmental stressors like heat.
Read More
Most Useful Reviews
9.5
Consistent daily support
Great for Depression! This is the only thing I've found that helps with my depression. I have always suffered from anxiety and depression, sometimes so debilitating that I could hardly get out of bed. This helps me stay productive and think logically. I take 1200mg daily to manage my depression and increase to 1600mg during stressful periods.
Read More
8.8
Reduced anxiety
Sounds promising. I’m taking megavitamins, which are helping, but I realise that it may not be easy for this to disappear. Therefore, I feel less anxious about it fading away, allowing me to remain assured.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
8
Vitamin E alleviates anxiety symptoms
Coenzyme Q10 and vitamin E alleviate heat stress-induced mood disturbances in male mice: Modulation of inflammatory pathways and the HPA axis.
Combination treatment complicates effects
In our exploration of how vitamin E affects anxiety, we studied male mice that were exposed to heat stress, which is known to trigger symptoms of anxiety and depression. We divided the mice into five groups: a control group, a heat stress group, and three treatment groups that received either vitamin E, coenzyme Q10, or a combination of both.
Over the course of 14 days, the heat-stressed mice underwent daily treatments, and we conducted various behavioral tests to measure signs of anxiety and depression. Remarkably, we discovered that both vitamin E alone and in combination with coenzyme Q10 provided significant relief from anxiety-related behaviors.
This was evident as we observed lowered anxiety levels and decreased despair behaviors in the treated groups compared to those that only experienced heat stress. Additionally, we noted a reduction in serum levels of corticosterone, a hormone associated with stress, which further supports the beneficial effects of vitamin E.
By modulating inflammatory pathways and influencing brain function, vitamin E, along with coenzyme Q10, appears to help counteract the negative emotional impacts of environmental stressors like heat.
Over the course of 14 days, the heat-stressed mice underwent daily treatments, and we conducted various behavioral tests to measure signs of anxiety and depression. Remarkably, we discovered that both vitamin E alone and in combination with coenzyme Q10 provided significant relief from anxiety-related behaviors.
This was evident as we observed lowered anxiety levels and decreased despair behaviors in the treated groups compared to those that only experienced heat stress. Additionally, we noted a reduction in serum levels of corticosterone, a hormone associated with stress, which further supports the beneficial effects of vitamin E.
By modulating inflammatory pathways and influencing brain function, vitamin E, along with coenzyme Q10, appears to help counteract the negative emotional impacts of environmental stressors like heat.
Read More
7
Vitamin E benefits menopause mood disorders
Ameliorative effect of α-tocopherol and tocotrienol-rich palm oil extract on menopause-associated mood disorder in ovariectomized mice.
Investigates vitamin E and anxiety
We explored the effects of vitamin E on anxiety and depression, particularly in the context of menopause-related mood disorders. To conduct this research, we studied ovariectomized mice—an animal model representing estrogen deficiency.
Our findings indicated that ovariectomized mice exhibited behaviors linked to depression and anxiety. Notably, these mice had higher levels of corticosterone, a hormone that signals stress, compared to a control group. We observed that administering α-tocopherol (a form of vitamin E) and tocotrienol-rich palm oil extract significantly reduced these mood disturbances over a two-week period.
While both treatments helped alleviate anxiety and depressive behaviors, tocotrienol-rich palm oil extract showed a more pronounced effect, particularly in mice under chronic stress. Additionally, both forms of vitamin E were effective in lowering elevated corticosterone levels, suggesting that they may help modulate the body’s stress response.
Overall, our research supports the potential of vitamin E as a promising treatment for mood disorders associated with menopause, highlighting its role in improving psychological well-being.
Our findings indicated that ovariectomized mice exhibited behaviors linked to depression and anxiety. Notably, these mice had higher levels of corticosterone, a hormone that signals stress, compared to a control group. We observed that administering α-tocopherol (a form of vitamin E) and tocotrienol-rich palm oil extract significantly reduced these mood disturbances over a two-week period.
While both treatments helped alleviate anxiety and depressive behaviors, tocotrienol-rich palm oil extract showed a more pronounced effect, particularly in mice under chronic stress. Additionally, both forms of vitamin E were effective in lowering elevated corticosterone levels, suggesting that they may help modulate the body’s stress response.
Overall, our research supports the potential of vitamin E as a promising treatment for mood disorders associated with menopause, highlighting its role in improving psychological well-being.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.7
9.5
Consistent daily support
Great for Depression! This is the only thing I've found that helps with my depression. I have always suffered from anxiety and depression, sometimes so debilitating that I could hardly get out of bed. This helps me stay productive and think logically. I take 1200mg daily to manage my depression and increase to 1600mg during stressful periods.
Read More
8.8
Reduced anxiety
Sounds promising. I’m taking megavitamins, which are helping, but I realise that it may not be easy for this to disappear. Therefore, I feel less anxious about it fading away, allowing me to remain assured.
