We investigated the potential of vitamin D3, also known as cholecalciferol, in combating cancer while addressing concerns about its toxicity at higher doses. This study focused on enhancing the effectiveness of vitamin D3 through a clever method called liposomal encapsulation, which helps minimize side effects.
We prepared liposomal vitamin D3 (VD-LP) and conducted various tests to understand its capabilities. We found that this encapsulated form not only maintained high efficiency but also demonstrated improved stability. Our analyses showed that VD-LP had strong effects against cancer cells from colorectal, breast, and prostate cancers. Remarkably, it affected gene expression in immune cells, boosting elements that help fight infections and support the body's defenses.
Notably, VD-LP did a great job slowing tumor growth in mice and improved their survival rates without causing adverse effects like hypercalcemia, which is often a concern with regular vitamin D3 use. This evidence indicates that liposomal encapsulation of vitamin D3 could offer an effective cancer treatment strategy while minimizing unwanted side effects.
We believe this may pave the way for further research and clinical applications, showcasing vitamin D3 as a valuable addition to cancer therapy.
Read More
9
Vitamin D3 derivatives improve cancer treatment
Synthetic Studies on Vitamin D Derivatives with Diverse but Selective Biological Activities.
We focused on how modified forms of vitamin D3 can positively affect cancer treatment. The study revealed that a specific derivative, known as MART-10, demonstrated significant anti-tumor effects in mouse models. When administered at low doses, this compound showed robust anti-cancer activity against BxpC-3 cancer cells.
Additionally, we explored a new vitamin D analog, AH-1, which was found to enhance bone formation without the usual side effects associated with vitamin D treatments. This is particularly promising for osteoporosis patients. Another derivative named NS-74c even exhibited potent antagonist activity against the vitamin D receptor, indicating a potential for varied therapeutic uses.
Overall, our research highlighted the potential of vitamin D3 derivatives to tackle cancer while minimizing adverse effects. This approach opens new doors for therapeutic options in oncology, providing a glimpse into how modified vitamin D can improve treatment outcomes for patients.
Read More
8
Vitamin D's potential in CRC
Exploration and Identification of Vitamin D and Related Genes as Potential Biomarkers for Colorectal Tumors.
We delved into the intriguing relationship between vitamin D and colorectal cancer (CRC) to uncover how this nutrient might influence cancer development and treatment. The study involved measuring the serum levels of active vitamin D (1,25(OH)D) in different groups, including those with normal conditions, colorectal adenomas (CRA), and colorectal cancer (CRC).
Our findings highlighted a significant drop in vitamin D levels in CRC patients, with levels falling to 19.00 µg/mL compared to 42.99 µg/mL in normal individuals. Additionally, we conducted bioinformatics analysis to pinpoint genes linked to vitamin D and colorectal cancer, testing these using HCT116 and HT29 cell lines.
We observed that vitamin D can inhibit the growth and spread of colon cancer cells, leading to a reduction in the activity of certain cancer-promoting genes. Interestingly, our analysis also showed that a diagnostic model based on five key vitamin D-related genes exhibited high diagnostic efficiency. This reveals vitamin D's potential as a supportive approach for CRC diagnosis and treatment, offering hope for improved cancer management.
Read More
Most Useful Reviews
6
Improved symptoms
3 people found this helpful
I consumed these for two months, bringing my vitamin D level from 22 to 70. The improvement was unexpected, especially as my cold frequency decreased and my symptoms of anxiety and health anxiety improved. I also noticed better sleep.
Read More
9
Boosts mood
This vitamin D3 from a reputable brand effectively elevates my mood and energy levels and assists with depression. It is crucial for bone growth and also helps regulate cancer cell growth.
Read More
7.5
Balanced hormones
The quality of the ingredients is excellent. This vitamin D3 regulates insulin, balances blood sugar, and reduces menopause symptoms. It's essential for synthesising oestrogens and crucial for the immune system to fight cancer.
We explored the potential of vitamin D-based micelles designed to deliver paclitaxel, a key chemotherapy drug, specifically for pancreatic cancer treatment. This study focuses on developing enzyme-responsive micelles that not only carry paclitaxel but also utilize vitamin D as an integral part of the delivery system.
The micelles are made by combining vitamin D with polyethylene glycol, resulting in tiny structures that can release their drug load when interacting with enzymes typically found in pancreatic cancer cells. We observed that these micelles showed promising results in laboratory settings, enhancing the effectiveness of paclitaxel against aggressive pancreatic cancer cells compared to using paclitaxel alone.
Moreover, we noted that the vitamin D in the micelles may play a dual role: serving as both a hydrophobic core for drug delivery and a contributor to synergetic therapeutic effects. Our findings suggest that leveraging vitamin D in this way could increase the efficacy of existing treatment options for pancreatic cancer patients, which is particularly significant given the challenges currently faced in treating this disease.
Read More
9
Vitamin D3 derivatives improve cancer treatment
Synthetic Studies on Vitamin D Derivatives with Diverse but Selective Biological Activities.
We focused on how modified forms of vitamin D3 can positively affect cancer treatment. The study revealed that a specific derivative, known as MART-10, demonstrated significant anti-tumor effects in mouse models. When administered at low doses, this compound showed robust anti-cancer activity against BxpC-3 cancer cells.
Additionally, we explored a new vitamin D analog, AH-1, which was found to enhance bone formation without the usual side effects associated with vitamin D treatments. This is particularly promising for osteoporosis patients. Another derivative named NS-74c even exhibited potent antagonist activity against the vitamin D receptor, indicating a potential for varied therapeutic uses.
Overall, our research highlighted the potential of vitamin D3 derivatives to tackle cancer while minimizing adverse effects. This approach opens new doors for therapeutic options in oncology, providing a glimpse into how modified vitamin D can improve treatment outcomes for patients.
Read More
8
Vitamin D analogs in prostate cancer
[New insights of vitamin D-based therapy for prostate cancer].
We explored the potential benefits of a vitamin D analog in treating prostate cancer, which is a major cause of cancer-related deaths among men. Our work focused on understanding how this vitamin D form impacts cancer resistance and the tumor microenvironment. We used the Pten mouse model to observe the therapeutic effects of the vitamin D analog.
One significant finding was that combining this vitamin D analog with the chemotherapy drug docetaxel could overcome resistance seen in some prostate cancer cases. This combination showed promising results in primary cancer spheroids and xenografts from a patient whose cancer had resisted both docetaxel and androgen deprivation therapy.
These insights suggest that vitamin D analogs might offer new and effective strategies for managing advanced prostate cancer, particularly for those patients who have not responded well to standard treatments.
Read More
8
Vitamin D3 offers anti-cancer benefits
Liposomal encapsulation of cholecalciferol mitigates toxicity and delays tumor growth.
We investigated the potential of vitamin D3, also known as cholecalciferol, in combating cancer while addressing concerns about its toxicity at higher doses. This study focused on enhancing the effectiveness of vitamin D3 through a clever method called liposomal encapsulation, which helps minimize side effects.
We prepared liposomal vitamin D3 (VD-LP) and conducted various tests to understand its capabilities. We found that this encapsulated form not only maintained high efficiency but also demonstrated improved stability. Our analyses showed that VD-LP had strong effects against cancer cells from colorectal, breast, and prostate cancers. Remarkably, it affected gene expression in immune cells, boosting elements that help fight infections and support the body's defenses.
Notably, VD-LP did a great job slowing tumor growth in mice and improved their survival rates without causing adverse effects like hypercalcemia, which is often a concern with regular vitamin D3 use. This evidence indicates that liposomal encapsulation of vitamin D3 could offer an effective cancer treatment strategy while minimizing unwanted side effects.
We believe this may pave the way for further research and clinical applications, showcasing vitamin D3 as a valuable addition to cancer therapy.
Read More
8
Vitamin D's potential in CRC
Exploration and Identification of Vitamin D and Related Genes as Potential Biomarkers for Colorectal Tumors.
We delved into the intriguing relationship between vitamin D and colorectal cancer (CRC) to uncover how this nutrient might influence cancer development and treatment. The study involved measuring the serum levels of active vitamin D (1,25(OH)D) in different groups, including those with normal conditions, colorectal adenomas (CRA), and colorectal cancer (CRC).
Our findings highlighted a significant drop in vitamin D levels in CRC patients, with levels falling to 19.00 µg/mL compared to 42.99 µg/mL in normal individuals. Additionally, we conducted bioinformatics analysis to pinpoint genes linked to vitamin D and colorectal cancer, testing these using HCT116 and HT29 cell lines.
We observed that vitamin D can inhibit the growth and spread of colon cancer cells, leading to a reduction in the activity of certain cancer-promoting genes. Interestingly, our analysis also showed that a diagnostic model based on five key vitamin D-related genes exhibited high diagnostic efficiency. This reveals vitamin D's potential as a supportive approach for CRC diagnosis and treatment, offering hope for improved cancer management.
I consumed these for two months, bringing my vitamin D level from 22 to 70. The improvement was unexpected, especially as my cold frequency decreased and my symptoms of anxiety and health anxiety improved. I also noticed better sleep.
Read More
9
Boosts mood
This vitamin D3 from a reputable brand effectively elevates my mood and energy levels and assists with depression. It is crucial for bone growth and also helps regulate cancer cell growth.
Read More
7.5
Balanced hormones
The quality of the ingredients is excellent. This vitamin D3 regulates insulin, balances blood sugar, and reduces menopause symptoms. It's essential for synthesising oestrogens and crucial for the immune system to fight cancer.
Read More
7.5
Reduced cancer risk
This vitamin effectively increases vitamin D levels, enhancing bone health and reducing chronic disease, including some cancers. It also strengthens the immune system, promoting healthy cell growth and dental health.
Read More
7.5
Inhibits cancer growth
Vitamin D aids calcium absorption, enhancing bone growth. It also plays a protective role, inhibiting cancer cell growth, aiding immune responses, and reducing inflammation severity.
Cancer is a complex group of diseases characterized by uncontrolled growth and spread of abnormal cells in the body. These cells can form tumors, invade nearby tissues, and metastasize to other parts of the body via the bloodstream or lymphatic system. While cancer can affect nearly any part of the body, it is classified into various types, including carcinomas, sarcomas, leukemia, and lymphomas, each originating from different types of cells. Risk factors for developing cancer can include genetic predisposition, lifestyle choices such as smoking and diet, environmental exposures, and certain infections.
Diagnosis typically involves medical imaging, biopsies, and a thorough review of personal and family health histories. Treatment options vary widely depending on the type and stage of cancer and may include surgery, chemotherapy, radiation therapy, immunotherapy, and targeted therapies. Early detection is crucial and can significantly improve treatment outcomes, leading to better survival rates. As awareness and research continue to advance, new methods for prevention, detection, and treatment of cancer are consistently being developed, offering hope to those affected by this challenging disease.
Vitamin D is a fat-soluble vitamin that's essential for maintaining healthy bones and teeth, supporting immune system function, and facilitating normal cell growth and development. It plays a crucial role in calcium absorption in the gut, which is vital for bone health. Unlike most vitamins, our bodies can produce Vitamin D when exposed to sunlight, specifically UVB rays, which is why it’s often referred to as the "sunshine vitamin." However, depending on your geographical location, lifestyle, and skin type, getting sufficient Vitamin D from the sun alone can be challenging, particularly during the winter months.
In addition to sunlight, Vitamin D can be obtained from certain foods such as fatty fish (like salmon and mackerel), fish liver oils, and fortified foods like milk and cereals. Some individuals may also consider supplements, especially if they're at risk for deficiency. Insufficient vitamin D levels are linked to various health issues, including rickets in children, osteomalacia in adults, and even an increased risk of chronic diseases. Regularly checking your vitamin D levels and consulting with a healthcare professional can help ensure you're meeting your needs for optimal health.
While there is ongoing research into the role of vitamin D in cancer prevention and treatment, the findings remain inconclusive. Some studies suggest that adequate levels of vitamin D may be associated with a lower risk of certain cancers, such as colorectal cancer and breast cancer, potentially due to its role in regulating cell growth and differentiation. However, definitive evidence proving that vitamin D supplements can prevent or successfully treat cancer is still lacking.
It’s important to approach the idea of using vitamin D as a cancer treatment with caution. Current guidelines recommend obtaining vitamin D primarily through safe sun exposure and diet. If you’re considering vitamin D supplementation, particularly for cancer-related purposes, it’s crucial to consult with a healthcare provider. They can provide personalized advice based on individual health needs and the latest research, ensuring that any approach to cancer management is both safe and effective.
Based on user reviews, the timeline for seeing results from Vitamin D supplements can vary, but many users report noticeable improvements within a couple of months. For instance, one user mentioned a significant increase in their vitamin D levels after two months of supplementation, along with benefits such as reduced cold frequency and improvements in anxiety symptoms Read Review. Another user highlighted the positive effects on their overall immune health and cancer-related symptoms, emphasizing the importance of consistent usage to achieve these benefits Read Review.
It's important to note that the effectiveness of Vitamin D supplements not only aids in improving bone health and mood but also plays a role in regulating cancer cell growth, as supported by multiple users' experiences Read Review. Overall, while individual experiences may differ, a timeframe of 1 to 2 months appears to be common for observing positive changes related to immune function and overall health.
Vitamin D has been the focus of various scientific studies exploring its potential role in cancer treatment and prevention, yielding promising results across different types of cancer. For instance, research has shown that a vitamin D analog combined with chemotherapy can effectively overcome drug resistance in prostate cancer, presenting a new strategy for managing advanced cases [1]. Additionally, significant differences in vitamin D levels observed between patients with benign and malignant breast diseases suggest that vitamin D deficiency may increase breast cancer risk, pointing to the supplement's possible preventive benefits [2].
Moreover, novel delivery methods utilizing vitamin D for drug transport in pancreatic cancer treatment have exhibited enhanced therapeutic effects, indicating that vitamin D can play a dual role in cancer therapy [3]. Other studies have indicated that vitamin D3 may positively influence cancer metabolism and even inhibit growth in certain cancer cells, such as in colorectal cancer [7]. Overall, while evidence suggests vitamin D has the potential for both treatment and prevention across various cancers, researchers advocate for further investigations to establish comprehensive guidelines and optimize therapeutic applications.
Based on user reviews, many individuals have reported a range of improvements in symptoms after using Vitamin D supplements. Several users noted enhanced overall mood and energy levels, with one user specifically mentioning that their anxiety symptoms diminished significantly alongside better sleep after two months of supplementation Read Review. Users have also reported benefits in physical health, such as improved bone health due to better calcium absorption and reduced chronic disease risk, including certain cancers Read Review.
Additionally, some users highlighted the cognitive and immune system support provided by Vitamin D, emphasizing its role in regulating insulin, balancing blood sugar levels, and empowering the body to fight illnesses, including cancer Read Review. While these anecdotal experiences paint a positive picture of the potential benefits of Vitamin D supplementation, individual results can vary significantly based on factors such as dosage, personal health conditions, and lifestyle.
Based on user reviews, many individuals have reported positive experiences when combining Vitamin D supplements with other treatments for managing cancer. Users highlighted the crucial role of Vitamin D in regulating cancer cell growth and supporting overall immune function, essential for fighting illnesses. One user specifically noted that Vitamin D aids in calcium absorption, enhancing both bone health and the body's ability to respond to cancer effectively Read Review. Another user emphasized the importance of Vitamin D in synthesizing estrogens and its critical contribution to the immune system's cancer-fighting capabilities Read Review.
Moreover, users mentioned that Vitamin D not only improves physical health but also positively impacts mood and overall well-being, which can be beneficial during cancer treatment. One reviewer reported improved mood and energy levels, which could be an important aspect for those undergoing therapy Read Review. Overall, many users express optimism about incorporating Vitamin D with other supplements to enhance their health and combat cancer, suggesting that this combination could potentially provide holistic support during their treatment journey.
Based on user reviews, many have reported significant improvements in their health, suggesting that finding the right dose of Vitamin D can be crucial in managing cancer. For instance, one user shared that they increased their vitamin D level from 22 to 70 in just two months, which was accompanied by a decline in cold frequency and improved anxiety symptoms Read Review. Another user pointed out that Vitamin D is essential for the immune system to fight cancer, highlighting its broader role in health and disease prevention Read Review.
Additionally, numerous users emphasized the protective role of Vitamin D in inhibiting cancer cell growth and improving immune responses. One reviewer noted that it enhances bone health and supports the body in fighting chronic diseases, including certain cancers Read Review. Others remarked on its benefits for calcium absorption and overall health improvements, suggesting that appropriate dosages can lead to enhanced well-being Read Review. While specific dosage recommendations were not detailed in the reviews, the consensus seems to advocate for a thoughtful approach in determining the right intake for individual health needs.
6
Improved symptoms
3 people found this helpful
I consumed these for two months, bringing my vitamin D level from 22 to 70. The improvement was unexpected, especially as my cold frequency decreased and my symptoms of anxiety and health anxiety improved. I also noticed better sleep.
7.5
Protects from cancer
I chose these vitamins for their quality. They are easy to swallow and absorb. Vitamin D aids calcium absorption for bone health and reduces cancer cell growth while supporting the immune system.
9
Boosts mood
This vitamin D3 from a reputable brand effectively elevates my mood and energy levels and assists with depression. It is crucial for bone growth and also helps regulate cancer cell growth.
7.5
Reduced cancer risk
This vitamin effectively increases vitamin D levels, enhancing bone health and reducing chronic disease, including some cancers. It also strengthens the immune system, promoting healthy cell growth and dental health.
7.5
Balanced hormones
The quality of the ingredients is excellent. This vitamin D3 regulates insulin, balances blood sugar, and reduces menopause symptoms. It's essential for synthesising oestrogens and crucial for the immune system to fight cancer.
7.5
Inhibits cancer growth
Vitamin D aids calcium absorption, enhancing bone growth. It also plays a protective role, inhibiting cancer cell growth, aiding immune responses, and reducing inflammation severity.
8
Vitamin D analogs in prostate cancer
[New insights of vitamin D-based therapy for prostate cancer].
We explored the potential benefits of a vitamin D analog in treating prostate cancer, which is a major cause of cancer-related deaths among men. Our work focused on understanding how this vitamin D form impacts cancer resistance and the tumor microenvironment. We used the Pten mouse model to observe the therapeutic effects of the vitamin D analog.
One significant finding was that combining this vitamin D analog with the chemotherapy drug docetaxel could overcome resistance seen in some prostate cancer cases. This combination showed promising results in primary cancer spheroids and xenografts from a patient whose cancer had resisted both docetaxel and androgen deprivation therapy.
These insights suggest that vitamin D analogs might offer new and effective strategies for managing advanced prostate cancer, particularly for those patients who have not responded well to standard treatments.
5
Vitamin D's role in breast disease
Levels of Serum 25-Hydroxy Vitamin D in Benign and Malignant Breast Disease Patients: An Observational Study.
We conducted an observational study to examine the levels of vitamin D in female patients with benign and malignant breast diseases. The research aimed to determine if there is a significant difference in vitamin D levels between those with non-cancerous conditions and those diagnosed with breast cancer.
During the study, we analyzed adult female patients admitted to a surgical department. Importantly, we excluded those who had taken vitamin D supplements recently or who had prior vitamin D deficiencies. By measuring serum vitamin D levels through a specific testing method, we were able to gather meaningful data about their relationship to breast health.
Our findings indicated a notable difference in average vitamin D levels when comparing the two groups. This suggests that inadequate vitamin D could be linked to an increased risk of developing breast cancer. Therefore, we explored the potential benefits of vitamin D supplementation as a preventive measure against breast cancer—though we acknowledge that larger and more controlled studies are essential to draw firm conclusions.
At the same time, we recognize that vitamin D has effects beyond bone health, and it is crucial to consider these broader impacts when discussing its role in cancer risk.
9
Vitamin D enhances chemotherapy delivery
Enzyme-responsive vitamin D-based micelles for paclitaxel-controlled delivery and synergistic pancreatic cancer therapy.
We explored the potential of vitamin D-based micelles designed to deliver paclitaxel, a key chemotherapy drug, specifically for pancreatic cancer treatment. This study focuses on developing enzyme-responsive micelles that not only carry paclitaxel but also utilize vitamin D as an integral part of the delivery system.
The micelles are made by combining vitamin D with polyethylene glycol, resulting in tiny structures that can release their drug load when interacting with enzymes typically found in pancreatic cancer cells. We observed that these micelles showed promising results in laboratory settings, enhancing the effectiveness of paclitaxel against aggressive pancreatic cancer cells compared to using paclitaxel alone.
Moreover, we noted that the vitamin D in the micelles may play a dual role: serving as both a hydrophobic core for drug delivery and a contributor to synergetic therapeutic effects. Our findings suggest that leveraging vitamin D in this way could increase the efficacy of existing treatment options for pancreatic cancer patients, which is particularly significant given the challenges currently faced in treating this disease.
8
Vitamin D's potential in CRC
Exploration and Identification of Vitamin D and Related Genes as Potential Biomarkers for Colorectal Tumors.
We delved into the intriguing relationship between vitamin D and colorectal cancer (CRC) to uncover how this nutrient might influence cancer development and treatment. The study involved measuring the serum levels of active vitamin D (1,25(OH)D) in different groups, including those with normal conditions, colorectal adenomas (CRA), and colorectal cancer (CRC).
Our findings highlighted a significant drop in vitamin D levels in CRC patients, with levels falling to 19.00 µg/mL compared to 42.99 µg/mL in normal individuals. Additionally, we conducted bioinformatics analysis to pinpoint genes linked to vitamin D and colorectal cancer, testing these using HCT116 and HT29 cell lines.
We observed that vitamin D can inhibit the growth and spread of colon cancer cells, leading to a reduction in the activity of certain cancer-promoting genes. Interestingly, our analysis also showed that a diagnostic model based on five key vitamin D-related genes exhibited high diagnostic efficiency. This reveals vitamin D's potential as a supportive approach for CRC diagnosis and treatment, offering hope for improved cancer management.
References
Len-Tayon K, Metzger D, Laverny G. [New insights of vitamin D-based therapy for prostate cancer]. Med Sci (Paris). 2025;41:154. 10.1051/medsci/2025011
Soni D, Tiwari A, Kushwah PS, Dubey S, Khan S. Levels of Serum 25-Hydroxy Vitamin D in Benign and Malignant Breast Disease Patients: An Observational Study. Cureus. 2025;17:e78283. 10.7759/cureus.78283
Peixoto D, Ravasco JM, Blanco-Fernandez B, Veiga F, Concheiro A, et al. Enzyme-responsive vitamin D-based micelles for paclitaxel-controlled delivery and synergistic pancreatic cancer therapy. Mater Today Bio. 2025;31:101555. 10.1016/j.mtbio.2025.101555
Xu N, Lin H, Ding X, Wang P, Lin JM. Isotope tracing-assisted chip-based solid-phase extraction mass spectrometry for monitoring metabolic changes and vitamin D3 regulation in cells. Talanta. 2025;288:127754. 10.1016/j.talanta.2025.127754
Jo Y, Kushram P, Bose S. Curcumin and vitamin D3 release from calcium phosphate enhances bone regeneration. Biomater Sci. 2025. 10.1039/d4bm01188k
Ezcurra-Hualde M, Zalba S, Bella Á, Arrizabalaga L, Risson A, et al. Liposomal encapsulation of cholecalciferol mitigates toxicity and delays tumor growth. Front Immunol. 2025;16:1529007. 10.3389/fimmu.2025.1529007
Wang L, Xu R, Wang M, Wang M, Su S, et al. Exploration and Identification of Vitamin D and Related Genes as Potential Biomarkers for Colorectal Tumors. Onco Targets Ther. 2025;18:129. 10.2147/OTT.S495066
Evans H, Greenhough A, Perry L, Lasanta G, Gonzalez CM, et al. Hypoxia Compromises the Differentiation of Human Osteosarcoma Cells to CAR-R, a Hydroxylated Derivative of Lithocholic Acid and Potent Agonist of the Vitamin D Receptor. Int J Mol Sci. 2025;26. 10.3390/ijms26010365
Kittaka A. Synthetic Studies on Vitamin D Derivatives with Diverse but Selective Biological Activities. Chem Pharm Bull (Tokyo). 2025;73:1. 10.1248/cpb.c24-00598
He W, Lv W, Liu L, Gong Y, Song K, et al. Enhanced Antiglioma Effect by a Vitamin D3-Inserted Lipid Hybrid Neutrophil Membrane Biomimetic Multimodal Nanoplatform. ACS Nano. 2024;18:35559. 10.1021/acsnano.4c13470
Almassri HF, Abdul Kadir A, Srour M, Foo LH. The Effects of Omega-3 Fatty Acids and Vitamin D Supplementation on the Nutritional Status of Women with Breast Cancer in Palestine: An Open-Label Randomized Controlled Trial. Nutrients. 2024;16. 10.3390/nu16223960
Maturana-Ramiìrez A, Aitken-Saavedra J, Rojas-Zúñiga G, Rojas-Alcayaga G, Espinoza-Santander I, et al. Hypovitaminosis D in patients with oral squamous cell carcinoma: Is a risk factor of developing this neoplasia?. Med Oral Patol Oral Cir Bucal. 2025;30:e24. 10.4317/medoral.26692
Almassri HF, Abdul Kadir A, Srour M, Foo LH. The effects of Omega-3 fatty acids and vitamin D supplementation on the quality of life and blood inflammation markers in newly diagnosed breast cancer women: An open-labelled randomised controlled trial. Clin Nutr ESPEN. 2025;65:64. 10.1016/j.clnesp.2024.11.014
García-Martínez JM, Chocarro-Calvo A, Martínez-Useros J, Regueira-Acebedo N, Fernández-Aceñero MJ, et al. SIRT1 Mediates the Antagonism of Wnt/β-Catenin Pathway by Vitamin D in Colon Carcinoma Cells. Int J Biol Sci. 2024;20:5495. 10.7150/ijbs.95875