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SCIENTIFIC SCORE
Questionable
Based on 9 Researches
6.4
USERS' SCORE
Good
Based on 9 Reviews
8.6
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin D3 (as Cholecalciferol) (from Lanolin)
125 mcg (5,000 IU)
625%
Top Medical Research Studies
7
Vitamin D3's role in anemia
Effect of vitamin D3-fortified fruit juice supplementation of 4000 IU daily on the recovery of iron status in childbearing-aged women with marginally low iron stores: Protocol for an 8-week, parallel group, double-blind randomized controlled trial.
Directly studies vitamin D3 and anemia
We conducted a study to see how vitamin D3 might help improve iron levels in women of childbearing age who had marginally low iron stores. Our approach involved a carefully designed 8-week randomized controlled trial, where 120 women aged between 19 and 40 were divided into two groups. One group received fruit juice fortified with 4000 IU of vitamin D3 daily, while the other had a placebo juice.
Throughout the study, we collected blood samples and monitored various health indicators every four weeks. We aimed to find out if the vitamin D3 supplementation could positively influence the iron status of the participants compared to the placebo.
Given the promising role of vitamin D in enhancing iron absorption, we hoped to uncover new insights into dietary strategies for managing iron deficiency. By observing the interaction over time between vitamin D levels and iron status, we aimed to provide valuable information on whether this fortification could serve as a practical alternative to traditional iron supplements.
As we gathered data, we explored the potential of vitamin D3 beyond its usual role, assessing if it could indeed help improve the anemia indicators in our target group.
Throughout the study, we collected blood samples and monitored various health indicators every four weeks. We aimed to find out if the vitamin D3 supplementation could positively influence the iron status of the participants compared to the placebo.
Given the promising role of vitamin D in enhancing iron absorption, we hoped to uncover new insights into dietary strategies for managing iron deficiency. By observing the interaction over time between vitamin D levels and iron status, we aimed to provide valuable information on whether this fortification could serve as a practical alternative to traditional iron supplements.
As we gathered data, we explored the potential of vitamin D3 beyond its usual role, assessing if it could indeed help improve the anemia indicators in our target group.
Read More
9
Vitamin D3 improves iron status
An 8-Week Vitamin D3-Fortified Fruit Drink Supplementation Increases Serum Ferritin Concentration: A Randomized Controlled Trial in Malaysian Women With Low Iron Stores.
Direct evaluation of vitamin D3
We conducted an 8-week, double-blind randomized controlled trial to see how vitamin D3-fortified fruit drinks affect iron levels in women with low iron stores. Our subjects, a group of 45 healthy women aged between 18 and 40, received either the vitamin D3 drink or a placebo, helping us assess the impact of this nutrient on their health.
Throughout the study, we measured key biomarkers such as serum ferritin, which indicates iron stores, and 25-hydroxyvitamin D, the active form of vitamin D in the body. After the 8 weeks, we noted a significant increase in both vitamin D levels and serum ferritin among those who participated in the vitamin D3-fortified drink regimen. This suggests that supplementing with vitamin D3 can indeed help improve iron stores in women who are iron deficient.
Given these findings, it becomes clear that there is potential for vitamin D to play a role in managing anemia. However, we also recognize the need for further research to confirm these effects and explore the safety and practicality of such fortifications across different populations.
Throughout the study, we measured key biomarkers such as serum ferritin, which indicates iron stores, and 25-hydroxyvitamin D, the active form of vitamin D in the body. After the 8 weeks, we noted a significant increase in both vitamin D levels and serum ferritin among those who participated in the vitamin D3-fortified drink regimen. This suggests that supplementing with vitamin D3 can indeed help improve iron stores in women who are iron deficient.
Given these findings, it becomes clear that there is potential for vitamin D to play a role in managing anemia. However, we also recognize the need for further research to confirm these effects and explore the safety and practicality of such fortifications across different populations.
Read More
7
Vitamin D3 impacts CKD anemia risk
Relationship between serum vitamin D3 concentration and anaemia in patients with chronic kidney disease in China.
Direct link between vitamin D3 and anemia
We explored how vitamin D3 levels relate to anemia in patients with chronic kidney disease (CKD) in China. In our study, 225 CKD patients were assigned to three groups based on their serum vitamin D3 levels: severe deficiency, deficiency, and sufficiency. Through our analysis, we measured the prevalence of anemia within these groups to identify any potential links.
The results were quite telling. Among the participants, 79.5% of those in the severe deficiency group had anemia, compared to 63.5% in the deficiency group, and 48.0% in the sufficiency group. This shows a clear trend—the more deficient the vitamin D3 levels, the higher the likelihood of experiencing anemia. We also noted that as the stages of CKD progressed, from 1 to 5, the prevalence of anemia increased significantly, peaking at almost 95% in the most advanced stage.
Our findings suggest that vitamin D3 deficiency may indeed elevate the risk of anemia in individuals suffering from CKD. Addressing vitamin D3 levels in these patients could be an essential factor in managing their anemia effectively.
The results were quite telling. Among the participants, 79.5% of those in the severe deficiency group had anemia, compared to 63.5% in the deficiency group, and 48.0% in the sufficiency group. This shows a clear trend—the more deficient the vitamin D3 levels, the higher the likelihood of experiencing anemia. We also noted that as the stages of CKD progressed, from 1 to 5, the prevalence of anemia increased significantly, peaking at almost 95% in the most advanced stage.
Our findings suggest that vitamin D3 deficiency may indeed elevate the risk of anemia in individuals suffering from CKD. Addressing vitamin D3 levels in these patients could be an essential factor in managing their anemia effectively.
Read More
Most Useful Reviews
9.5
Significant vitamin increase
My vitamin D rose from 14.2 to 45.3 ng/ml in 8 months, after I started taking 5000 IU alongside Omega-3. I noticed improvements in bone pain, hair loss, and energy levels after starting the supplement. Following my endocrinologist's advice, I adjusted the timing of my intake for better absorption. Vitamin D likely aided my recovery from coronavirus, and I aim to increase my levels further to enhance my health alongside managing my anaemia.
Read More
8.8
Improved tissue nourishment
Vitamin D3 is crucial for those with anemia. It enhances tissue nourishment, but one must be cautious about dosage. For example, if there's anaemia alongside vitamin D3 deficiency, start with small doses. Elderly individuals or those post-gastrointestinal surgery should opt for sublingual forms for better absorption. Co-factors like vitamin K2, magnesium, and vitamin A are vital, as their levels impact proper absorption and distribution. This supplement has effectively raised my vitamin D3 levels, which I consider beneficial for overall health.
Read More
9.5
Essential for wellbeing
These are excellent vitamins for preventing deficiencies. Vitamin D3 is essential for healthy functioning and aids iron absorption, which is vital for anaemia. The capsules are conveniently sized, and my doctor has approved their dosage. I recommend them for anyone dealing with anaemia or aiming for preventative health.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 9 Researches
6.4
9
Vitamin D3 improves iron status
An 8-Week Vitamin D3-Fortified Fruit Drink Supplementation Increases Serum Ferritin Concentration: A Randomized Controlled Trial in Malaysian Women With Low Iron Stores.
Direct evaluation of vitamin D3
We conducted an 8-week, double-blind randomized controlled trial to see how vitamin D3-fortified fruit drinks affect iron levels in women with low iron stores. Our subjects, a group of 45 healthy women aged between 18 and 40, received either the vitamin D3 drink or a placebo, helping us assess the impact of this nutrient on their health.
Throughout the study, we measured key biomarkers such as serum ferritin, which indicates iron stores, and 25-hydroxyvitamin D, the active form of vitamin D in the body. After the 8 weeks, we noted a significant increase in both vitamin D levels and serum ferritin among those who participated in the vitamin D3-fortified drink regimen. This suggests that supplementing with vitamin D3 can indeed help improve iron stores in women who are iron deficient.
Given these findings, it becomes clear that there is potential for vitamin D to play a role in managing anemia. However, we also recognize the need for further research to confirm these effects and explore the safety and practicality of such fortifications across different populations.
Throughout the study, we measured key biomarkers such as serum ferritin, which indicates iron stores, and 25-hydroxyvitamin D, the active form of vitamin D in the body. After the 8 weeks, we noted a significant increase in both vitamin D levels and serum ferritin among those who participated in the vitamin D3-fortified drink regimen. This suggests that supplementing with vitamin D3 can indeed help improve iron stores in women who are iron deficient.
Given these findings, it becomes clear that there is potential for vitamin D to play a role in managing anemia. However, we also recognize the need for further research to confirm these effects and explore the safety and practicality of such fortifications across different populations.
Read More
8
Vitamin D improves anemia management
[Cholecalciferol supplementation improves secondary hyperparathyroidism control in hemodialysis patients].
Impact of vitamin D3 acknowledged
We examined the impact of cholecalciferol (vitamin D3) supplementation on anemia in hemodialysis patients suffering from vitamin D deficiency and secondary hyperparathyroidism. Our study included 122 patients who had low vitamin D levels and high parathyroid hormone (PTH) levels. We divided the participants into two groups: one received cholecalciferol supplements, while the other served as a control group.
In the group that received cholecalciferol, we observed significant improvements. PTH levels decreased notably, from an average of 476 to 296 pg/mL, indicating better regulation of calcium balance in the body. Alongside this, the 25-hydroxyvitamin D levels rose from 10.3 to 33.5 ng/mL, demonstrating a successful increase in vitamin D status.
More encouragingly, we noticed that hemoglobin levels, which reflect anemia status, increased from 11.6 to 12.2 g/dL in the supplemented group. This rise illustrates a potential benefit of vitamin D3 supplementation in managing anemia among hemodialysis patients. Additionally, the patients needed less paricalcitol, another medication used for managing PTH levels, revealing a positive overall impact on their treatment regimen.
In the group that received cholecalciferol, we observed significant improvements. PTH levels decreased notably, from an average of 476 to 296 pg/mL, indicating better regulation of calcium balance in the body. Alongside this, the 25-hydroxyvitamin D levels rose from 10.3 to 33.5 ng/mL, demonstrating a successful increase in vitamin D status.
More encouragingly, we noticed that hemoglobin levels, which reflect anemia status, increased from 11.6 to 12.2 g/dL in the supplemented group. This rise illustrates a potential benefit of vitamin D3 supplementation in managing anemia among hemodialysis patients. Additionally, the patients needed less paricalcitol, another medication used for managing PTH levels, revealing a positive overall impact on their treatment regimen.
Read More
7
Vitamin D3's role in anemia
Effect of vitamin D3-fortified fruit juice supplementation of 4000 IU daily on the recovery of iron status in childbearing-aged women with marginally low iron stores: Protocol for an 8-week, parallel group, double-blind randomized controlled trial.
Directly studies vitamin D3 and anemia
We conducted a study to see how vitamin D3 might help improve iron levels in women of childbearing age who had marginally low iron stores. Our approach involved a carefully designed 8-week randomized controlled trial, where 120 women aged between 19 and 40 were divided into two groups. One group received fruit juice fortified with 4000 IU of vitamin D3 daily, while the other had a placebo juice.
Throughout the study, we collected blood samples and monitored various health indicators every four weeks. We aimed to find out if the vitamin D3 supplementation could positively influence the iron status of the participants compared to the placebo.
Given the promising role of vitamin D in enhancing iron absorption, we hoped to uncover new insights into dietary strategies for managing iron deficiency. By observing the interaction over time between vitamin D levels and iron status, we aimed to provide valuable information on whether this fortification could serve as a practical alternative to traditional iron supplements.
As we gathered data, we explored the potential of vitamin D3 beyond its usual role, assessing if it could indeed help improve the anemia indicators in our target group.
Throughout the study, we collected blood samples and monitored various health indicators every four weeks. We aimed to find out if the vitamin D3 supplementation could positively influence the iron status of the participants compared to the placebo.
Given the promising role of vitamin D in enhancing iron absorption, we hoped to uncover new insights into dietary strategies for managing iron deficiency. By observing the interaction over time between vitamin D levels and iron status, we aimed to provide valuable information on whether this fortification could serve as a practical alternative to traditional iron supplements.
As we gathered data, we explored the potential of vitamin D3 beyond its usual role, assessing if it could indeed help improve the anemia indicators in our target group.
Read More
7
Vitamin D epimers and anemia effects
Vitamin D epimers are associated with circulating haemoglobin levels independently of C-reactive protein.
Moderately relevant study findings
We explored the connection between vitamin D, particularly its epimer known as 3'-epi-25(OH)D, and anemia. The study analyzed data from 1,655 participants, examining how different forms of vitamin D relate to hemoglobin levels—a key indicator for anemia—while also considering other factors like age, sex, and body mass index (BMI).
Interestingly, we found that the total serum level of vitamin D didn't directly correlate with hemoglobin levels. However, when we focused on the 3'-epimeric form of vitamin D, we saw a significant association with hemoglobin levels, even when we accounted for age, sex, BMI, and high-sensitivity C-reactive protein (hsCRP). This suggests that 3'-epi-25(OH)D may have a unique role in improving hemoglobin levels, supporting its importance in red blood cell and iron metabolism.
On the other hand, the non-3'-epimeric form of vitamin D did not show a significant impact on hemoglobin levels. Overall, our findings highlight the potential benefits of vitamin D epimers in managing anemia and reinforce the need to look at vitamin D in its various forms when considering treatment options.
Interestingly, we found that the total serum level of vitamin D didn't directly correlate with hemoglobin levels. However, when we focused on the 3'-epimeric form of vitamin D, we saw a significant association with hemoglobin levels, even when we accounted for age, sex, BMI, and high-sensitivity C-reactive protein (hsCRP). This suggests that 3'-epi-25(OH)D may have a unique role in improving hemoglobin levels, supporting its importance in red blood cell and iron metabolism.
On the other hand, the non-3'-epimeric form of vitamin D did not show a significant impact on hemoglobin levels. Overall, our findings highlight the potential benefits of vitamin D epimers in managing anemia and reinforce the need to look at vitamin D in its various forms when considering treatment options.
Read More
7
Vitamin D3 impacts CKD anemia risk
Relationship between serum vitamin D3 concentration and anaemia in patients with chronic kidney disease in China.
Direct link between vitamin D3 and anemia
We explored how vitamin D3 levels relate to anemia in patients with chronic kidney disease (CKD) in China. In our study, 225 CKD patients were assigned to three groups based on their serum vitamin D3 levels: severe deficiency, deficiency, and sufficiency. Through our analysis, we measured the prevalence of anemia within these groups to identify any potential links.
The results were quite telling. Among the participants, 79.5% of those in the severe deficiency group had anemia, compared to 63.5% in the deficiency group, and 48.0% in the sufficiency group. This shows a clear trend—the more deficient the vitamin D3 levels, the higher the likelihood of experiencing anemia. We also noted that as the stages of CKD progressed, from 1 to 5, the prevalence of anemia increased significantly, peaking at almost 95% in the most advanced stage.
Our findings suggest that vitamin D3 deficiency may indeed elevate the risk of anemia in individuals suffering from CKD. Addressing vitamin D3 levels in these patients could be an essential factor in managing their anemia effectively.
The results were quite telling. Among the participants, 79.5% of those in the severe deficiency group had anemia, compared to 63.5% in the deficiency group, and 48.0% in the sufficiency group. This shows a clear trend—the more deficient the vitamin D3 levels, the higher the likelihood of experiencing anemia. We also noted that as the stages of CKD progressed, from 1 to 5, the prevalence of anemia increased significantly, peaking at almost 95% in the most advanced stage.
Our findings suggest that vitamin D3 deficiency may indeed elevate the risk of anemia in individuals suffering from CKD. Addressing vitamin D3 levels in these patients could be an essential factor in managing their anemia effectively.
Read More
User Reviews
USERS' SCORE
Good
Based on 9 Reviews
8.6
9.5
Significant vitamin increase
My vitamin D rose from 14.2 to 45.3 ng/ml in 8 months, after I started taking 5000 IU alongside Omega-3. I noticed improvements in bone pain, hair loss, and energy levels after starting the supplement. Following my endocrinologist's advice, I adjusted the timing of my intake for better absorption. Vitamin D likely aided my recovery from coronavirus, and I aim to increase my levels further to enhance my health alongside managing my anaemia.
Read More
9.5
Essential for wellbeing
These are excellent vitamins for preventing deficiencies. Vitamin D3 is essential for healthy functioning and aids iron absorption, which is vital for anaemia. The capsules are conveniently sized, and my doctor has approved their dosage. I recommend them for anyone dealing with anaemia or aiming for preventative health.
Read More
9.5
Boosts immune health
I've been taking 5000 IU of vitamin D3 for my anaemia for several months on my doctor's advice. It supports my immune system, especially during these times. I take one capsule daily with breakfast, and my experience has been very positive, enhancing my overall health.
8.8
Improved tissue nourishment
Vitamin D3 is crucial for those with anemia. It enhances tissue nourishment, but one must be cautious about dosage. For example, if there's anaemia alongside vitamin D3 deficiency, start with small doses. Elderly individuals or those post-gastrointestinal surgery should opt for sublingual forms for better absorption. Co-factors like vitamin K2, magnesium, and vitamin A are vital, as their levels impact proper absorption and distribution. This supplement has effectively raised my vitamin D3 levels, which I consider beneficial for overall health.
Read More
8.8
Supports immune system
I recommend these small, convenient capsules for everyone, particularly during the pandemic. They are odourless and tasteless, taken with food for better absorption. Vitamin D supports lung function and is crucial for individuals with anaemia, pregnant women, children, and the elderly. However, it's vital to consult a healthcare professional for proper dosage based on individual needs.
Read More
