We observed a fascinating phenomenon related to vitamin C and anemia during a series of cases in a prison setting in Ethiopia. Specifically, we examined how scurvy, a disease caused by a lack of vitamin C, contributed to anemia among prisoners.
Our study focused on ten patients who were admitted for treatment, all of whom presented with some form of leg swelling or pain. After administering vitamin C in the form of ascorbic acid, we noted a significant increase in hemoglobin levels, rising from an average of 4.6 to 7.1 g/dL. This improvement indicates that vitamin C may play a crucial role in alleviating some anemia symptoms when the underlying cause is related to dietary deficiencies.
Additionally, through an observational study involving 67 other patients in the same prison, we confirmed that leg swelling and pain were common symptoms among those affected. With consistent therapeutic doses of vitamin C, all patients showed considerable improvement in their conditions.
Thus, we can conclude that vitamin C does seem to have a valuable effect on anemia caused by dietary deficiencies, particularly in high-risk environments like prisons. This finding encourages healthcare providers to remain vigilant about such nutritional deficiencies and highlights the importance of vitamin C in treatment.
Read More
9
Nano-Bhasma enhances iron absorption
Advancements in Nano-Mandoor Bhasma: Unravelling the Particle Size-Ascorbic Acid Synergy for Enhanced Iron Bioavailability for Anemia Treatment.
We investigated how modifying Mandoor Bhasma, a traditional Ayurvedic medicine, could enhance its effectiveness in treating iron-deficiency anemia. By grinding this medicine into nanoparticles and coating them with ascorbic acid, we aimed to boost the iron bioavailability in our body.
In our study, we found that the surface-enhanced nano-Mandoor Bhasma exhibited better iron dissolution in conditions similar to those found in our intestines. This improvement was significant because it means that more iron becomes available for our bodies to absorb. Testing the effects on human colon cells revealed that cells treated with the modified version absorbed three times more iron compared to those treated with the standard version.
Furthermore, as the treated cells produced higher levels of a key protein related to iron storage, this signals an increase in the iron available for our body’s needs. Ultimately, this research suggests that using nanoscale formulations and vitamin C can significantly enhance the effectiveness of traditional iron treatments for anemia.
Read More
9
Novel chelate complex boosts iron
Harnessing the Power of a Novel Triple Chelate Complex in Fermented Probiotic Dairy Products: A Promising Solution for Combating Iron Deficiency Anemia.
We examined a novel approach to combat iron deficiency anemia by focusing on a unique triple chelate complex that combines iron, vitamin C (ascorbic acid), and essential amino acids. Our findings revealed that this complex can effectively increase iron levels in the body, particularly in fermented dairy products.
Importantly, we found that the fortification of milk with this complex doesn't require high concentrations—just a mere 0.005 mol/L is enough for effective results. Through our experiments with rat models, we observed a significant boost in serum iron levels after administering the complex, achieving a rise of 14.0 mmol/L within just 24 hours.
Furthermore, we studied how these complexes affected the taste and quality of dairy products, demonstrating that even at very low concentrations, they maintained desirable physicochemical properties. Among the various compounds we tested, iron ascorbate lysinate stood out as the most promising candidate for enhancing iron levels, making it a potential game-changer in diets for those suffering from iron deficiency anemia.
However, while we acknowledge the crucial role vitamin C plays in improving iron absorption, our focus on the triple chelate mechanism makes it challenging to isolate its individual effects solely on anemia.
Read More
Most Useful Reviews
7.5
Reduced fatigue
1 people found this helpful
I've taken vitamin C consistently and feel much more cheerful despite my hidden anemia and constant fatigue. During winter, upon feeling ill, I took a hefty dose three times a day and was pleasantly surprised that the usual cold did not develop as it typically would over four days. I'm very satisfied and will be ordering more. The tablets are large, and I find them difficult to swallow, but the results have been worth it.
Read More
9
Supports absorption
I take 4000mg of vitamin C daily, spacing the doses an hour apart. Vitamin C is crucial for boosting immunity and helps absorb iron, essential for those of us with anemia. It also supports collagen synthesis and provides antioxidant benefits. This high-dose C-1000 supplement is particularly beneficial for my increased Vitamin C needs.
Read More
9
Eases nausea
While treating anemia, I used vitamin C to enhance the absorption of iron supplements, which was a relief since iron tablets typically induce nausea. I'm grateful for this remedy.
We investigated how modifying Mandoor Bhasma, a traditional Ayurvedic medicine, could enhance its effectiveness in treating iron-deficiency anemia. By grinding this medicine into nanoparticles and coating them with ascorbic acid, we aimed to boost the iron bioavailability in our body.
In our study, we found that the surface-enhanced nano-Mandoor Bhasma exhibited better iron dissolution in conditions similar to those found in our intestines. This improvement was significant because it means that more iron becomes available for our bodies to absorb. Testing the effects on human colon cells revealed that cells treated with the modified version absorbed three times more iron compared to those treated with the standard version.
Furthermore, as the treated cells produced higher levels of a key protein related to iron storage, this signals an increase in the iron available for our body’s needs. Ultimately, this research suggests that using nanoscale formulations and vitamin C can significantly enhance the effectiveness of traditional iron treatments for anemia.
Read More
9
Novel chelate complex boosts iron
Harnessing the Power of a Novel Triple Chelate Complex in Fermented Probiotic Dairy Products: A Promising Solution for Combating Iron Deficiency Anemia.
We examined a novel approach to combat iron deficiency anemia by focusing on a unique triple chelate complex that combines iron, vitamin C (ascorbic acid), and essential amino acids. Our findings revealed that this complex can effectively increase iron levels in the body, particularly in fermented dairy products.
Importantly, we found that the fortification of milk with this complex doesn't require high concentrations—just a mere 0.005 mol/L is enough for effective results. Through our experiments with rat models, we observed a significant boost in serum iron levels after administering the complex, achieving a rise of 14.0 mmol/L within just 24 hours.
Furthermore, we studied how these complexes affected the taste and quality of dairy products, demonstrating that even at very low concentrations, they maintained desirable physicochemical properties. Among the various compounds we tested, iron ascorbate lysinate stood out as the most promising candidate for enhancing iron levels, making it a potential game-changer in diets for those suffering from iron deficiency anemia.
However, while we acknowledge the crucial role vitamin C plays in improving iron absorption, our focus on the triple chelate mechanism makes it challenging to isolate its individual effects solely on anemia.
Read More
9
Vitamin C aids anemia treatment
The Forgotten Disease in the 21st Century: Scurvy Outbreak in Hawassa Central Prison, Hawassa, Sidama, Southern Ethiopia, 2023.
We observed a fascinating phenomenon related to vitamin C and anemia during a series of cases in a prison setting in Ethiopia. Specifically, we examined how scurvy, a disease caused by a lack of vitamin C, contributed to anemia among prisoners.
Our study focused on ten patients who were admitted for treatment, all of whom presented with some form of leg swelling or pain. After administering vitamin C in the form of ascorbic acid, we noted a significant increase in hemoglobin levels, rising from an average of 4.6 to 7.1 g/dL. This improvement indicates that vitamin C may play a crucial role in alleviating some anemia symptoms when the underlying cause is related to dietary deficiencies.
Additionally, through an observational study involving 67 other patients in the same prison, we confirmed that leg swelling and pain were common symptoms among those affected. With consistent therapeutic doses of vitamin C, all patients showed considerable improvement in their conditions.
Thus, we can conclude that vitamin C does seem to have a valuable effect on anemia caused by dietary deficiencies, particularly in high-risk environments like prisons. This finding encourages healthcare providers to remain vigilant about such nutritional deficiencies and highlights the importance of vitamin C in treatment.
Read More
9
Vitamin C boosts iron absorption
Preparation, characterization, and bioavailability evaluation of antioxidant phosvitin peptide-ferrous complex.
We investigated how vitamin C can affect anemia, particularly through its interaction with a specific iron supplement called phosvitin peptide-ferrous complex. This complex is designed to enhance iron bioavailability, which is crucial in addressing iron deficiency anemia (IDA). Our analysis showed that when vitamin C was added to this complex, there was a notable increase in iron absorption.
The results indicated that the iron content increased significantly with the presence of vitamin C, which interacted synergistically to boost bioavailability. In fact, when vitamin C was added, the iron dialysis percentage increased, highlighting its potential role in improving the efficiency of iron absorption in the gut.
While our findings suggested significant benefits in enhancing iron absorption when combined with vitamin C, it's essential to recognize that the isolated effects of vitamin C on anemia were not fully evaluated in this study. Therefore, while the combination exhibited promising results, we can't definitively say that vitamin C alone provides a solution for anemia.
Read More
8
Fortified beverage impacts anemia study
Pearl millet instant beverage powder enriched with baobab pulp to improve iron and anaemia status of adolescent girls in rural Ghana: a study protocol for a cluster randomised controlled trial.
We explored the impact of a fortified beverage made from pearl millet and baobab pulp on the iron and anemia status of adolescent girls in rural Ghana. This was done through a cluster randomized controlled trial involving 258 participants. Girls were divided into three groups: one that received the fortified beverage, one that received an unfortified version, and another that got standard iron and folate supplements.
Importantly, the fortified beverage contained vitamin C, which is known to enhance iron absorption. However, the study didn't isolate the effects of vitamin C alone on anemia. Therefore, while we observed the positive potential of this fortified beverage, we can't definitively conclude that vitamin C had a direct impact.
Overall, the research aims to fill a gap in understanding how food-fortification strategies can fight iron deficiency anemia, which is a significant public health issue in this region. It’s exciting to think about how these findings might influence future dietary interventions for adolescent girls facing anemia.
I've taken vitamin C consistently and feel much more cheerful despite my hidden anemia and constant fatigue. During winter, upon feeling ill, I took a hefty dose three times a day and was pleasantly surprised that the usual cold did not develop as it typically would over four days. I'm very satisfied and will be ordering more. The tablets are large, and I find them difficult to swallow, but the results have been worth it.
Read More
9
Supports absorption
I take 4000mg of vitamin C daily, spacing the doses an hour apart. Vitamin C is crucial for boosting immunity and helps absorb iron, essential for those of us with anemia. It also supports collagen synthesis and provides antioxidant benefits. This high-dose C-1000 supplement is particularly beneficial for my increased Vitamin C needs.
Read More
9
Eases nausea
While treating anemia, I used vitamin C to enhance the absorption of iron supplements, which was a relief since iron tablets typically induce nausea. I'm grateful for this remedy.
Read More
9
Skin condition improved
I suffered from rough skin and anemia, so I used vitamin C with iron. Not only has my anemia improved, but my skin has also noticeably calmed down. I will continue taking it!
Read More
9
Essential supplement
This vitamin C is crucial for my megavitamin therapy aimed at curing severe anemia. Anemia has plagued me since childhood, and I believe I will always need to take both iron and this supplement even after I improve.
Anemia is a medical condition characterized by a deficiency of red blood cells or hemoglobin in the blood, which can result in reduced oxygen flow to the body's organs. The most common type of anemia is iron-deficiency anemia, which occurs when the body does not have enough iron to produce adequate hemoglobin. Other types can arise from chronic diseases, genetic conditions, or a lack of certain vitamins such as B12 or folate. Symptoms often include fatigue, weakness, pale skin, and shortness of breath, particularly during physical activity.
Diagnosing anemia typically involves blood tests to measure levels of red blood cells, hemoglobin concentration, and other related factors. Treatment varies depending on the underlying cause but may include dietary changes, supplements, or medications. In some cases, more serious interventions may be necessary, such as blood transfusions or treatments for associated conditions. If you suspect you have anemia, it's essential to consult a healthcare professional for appropriate evaluation and management.
Vitamin C, also known as ascorbic acid, is a water-soluble vitamin that plays a critical role in numerous bodily functions. As an essential nutrient, it contributes to the growth and repair of tissues in the body, and it is vital for the production of collagen, an important protein that helps maintain skin, cartilage, tendons, ligaments, and blood vessels. Additionally, Vitamin C acts as a powerful antioxidant, which means it helps combat free radicals—unstable molecules that can cause oxidative stress and contribute to various chronic diseases.
Moreover, Vitamin C enhances iron absorption from plant-based foods, making it a vital component for those following vegetarian or vegan diets. While many people get sufficient Vitamin C from a well-balanced diet that includes fruits and vegetables like oranges, strawberries, kiwi, broccoli, and bell peppers, some individuals might require supplementation. It's generally recommended to stay within the daily intake guidelines, as excessive consumption can lead to gastrointestinal disturbances. Overall, Vitamin C is not just a skincare celebrity—it's a fundamental part of maintaining overall health and well-being.
Vitamin C can play a supportive role in managing anemia, particularly iron-deficiency anemia. While it doesn't replace the need for iron itself, vitamin C is known to enhance the absorption of non-heme iron, which is the type of iron found in plant-based foods. Consuming vitamin C-rich foods like oranges, strawberries, or bell peppers alongside iron-rich foods can significantly improve iron absorption. For those managing anemia, incorporating vitamin C in your diet can be a simple and effective strategy.
However, it's important to note that while vitamin C can aid in iron absorption, it shouldn't be considered a standalone treatment for anemia. If you're experiencing symptoms of anemia, it's essential to consult with a healthcare provider to understand the underlying cause and appropriate treatment options. They may recommend a combination of dietary changes, iron supplements, or other interventions based on your specific situation.
Based on user reviews, the timeline for seeing results from vitamin C supplementation while treating anemia can vary. Many users report noticeable improvements in their conditions within a few weeks to a month of consistent use. For instance, one user mentioned using vitamin C alongside iron and noticing a significant improvement in both their anemia and skin condition after starting the regimen Read Review. Others have also indicated that taking vitamin C not only aids in iron absorption but contributes to an overall feeling of better health, suggesting that results can be realized fairly quickly when combined with proper iron supplementation Read Review.
However, it’s crucial to maintain regular and consistent dosing to maximize the benefits, as highlighted by users who emphasize the importance of daily intake for effectiveness Read Review. Some reviews suggest that while improvements can be seen relatively quickly, ongoing supplementation may be required for sustained benefits, particularly for those dealing with chronic anemia Read Review. It appears that many who commit to a vitamin C regimen alongside their iron supplements experience a quicker resolution of symptoms associated with anemia.
The research indicates that certain supplements containing vitamin C can support efforts to combat anemia, particularly by enhancing iron absorption. For instance, a study examined the impact of vitamin C-rich guava when added to meals of mungbean dal, which showed a significant increase in hemoglobin levels among children with anemia [1]. However, it is important to note that while vitamin C can enhance iron absorption, it may not significantly increase overall body iron stores. Similarly, other studies involving fortified beverages and innovative treatments, such as nanoscale formulations combined with vitamin C, demonstrate potential benefits for improving iron levels [2], [4], [3].
While the collective evidence points to the efficacy of vitamin C in bolstering iron absorption and improving anemia outcomes, the isolated effects of vitamin C alone are not fully substantiated by the available research. Several studies integrated vitamin C into a regimen with iron supplements or other therapeutic components, making it difficult to ascertain its impact independently [6], [8]. Therefore, while vitamin C-rich supplements can indeed support anemia management, particularly in specific contexts, comprehensive research is still needed to clarify their standalone effectiveness against the condition.
Based on user reviews, many individuals taking vitamin C report a variety of positive improvements in their symptoms related to anemia and overall health. For instance, one user shared that consistent vitamin C use not only alleviated feelings of fatigue but also prevented a seasonal cold that would have typically been debilitating Read Review. Another noted that the supplement significantly enhanced their iron absorption and helped reduce the nausea typically induced by iron tablets, highlighting its role in managing anemia more comfortably Read Review.
Users also report improvements beyond just anemia relief; several have observed enhancements in skin health, linking vitamin C's role in collagen synthesis to noticeable calming of their skin conditions Read Review. Additionally, the majority emphasize the importance of consistent, daily intake to maximize benefits, as irregular use can diminish its efficacy in aiding iron absorption Read Review. However, individual results can vary widely, and ongoing supplementation is often recommended for those with more chronic issues Read Review.
Based on user reviews, many individuals find that combining vitamin C with other supplements, particularly iron, can be very effective in managing anemia. Users often report that vitamin C enhances the absorption of iron, alleviating the common side effects associated with iron supplementation, such as nausea. One user noted that integrating vitamin C allowed them to feel relief during their anemia treatment, making it easier to tolerate iron tablets Read Review. Others have emphasized that this combination not only improved their anemia but also contributed positively to their overall health, including enhancements in skin condition and immune support Read Review.
Moreover, users highlight the importance of consistent daily intake of vitamin C to maximize its benefits. Several mention that taking vitamin C regularly, whether in high doses or in a time-release formula, has helped sustain its effectiveness in boosting iron absorption and supporting their anemia management Read Review. Additionally, some users have transitioned to capsule forms for convenience without losing the health benefits associated with vitamin C Read Review. Overall, the consensus indicates that combining vitamin C with iron supplements offers a multi-faceted approach to tackling anemia and improving overall well-being.
Based on user reviews, there seems to be a consensus around the importance of Vitamin C for enhancing iron absorption, especially for those dealing with anemia. Many users report taking significant doses, often 1000mg to 4000mg per day, to help alleviate their symptoms. One user noted their positive experience taking 4000mg daily, spaced out over several doses, which they found crucial for boosting their immunity and aiding iron absorption (Read Review). Another mentioned a dual approach of combining Vitamin C with iron supplements, emphasizing that it alleviated the nausea typically associated with iron tablets (Read Review).
Users also highlighted the necessity of consistent intake, as excess Vitamin C is quickly excreted from the body, underscoring the importance of maintaining regular doses for effective iron absorption. A review noted that taking Vitamin C alongside iron significantly improved their anemia and skin condition (Read Review). Overall, while the right dose may vary among individuals, the general recommendation from user experiences leans towards higher daily doses of Vitamin C, particularly when paired with iron supplementation for optimal anemia treatment.
9
Skin condition improved
I suffered from rough skin and anemia, so I used vitamin C with iron. Not only has my anemia improved, but my skin has also noticeably calmed down. I will continue taking it!
7.5
Supports immunity
I switched from tablets to capsules for convenience, taking a 1000mg dose. Vitamin C helps in combating anemia, improving iron absorption as well. Additionally, it supports calcium absorption, potentially aids in weight loss, and slows skin aging by assisting with collagen synthesis.
7.5
Enhanced absorption
I take vitamin C with other supplements every morning. The American version is larger than the Japanese ones. I understand that excess vitamin C is excreted quickly, so consistent intake is vital. The time-release formula allows for a sustained effect throughout the day, aiding both my anemia and iron absorption.
9
Essential supplement
This vitamin C is crucial for my megavitamin therapy aimed at curing severe anemia. Anemia has plagued me since childhood, and I believe I will always need to take both iron and this supplement even after I improve.
7.5
Reduced fatigue
1 people found this helpful
I've taken vitamin C consistently and feel much more cheerful despite my hidden anemia and constant fatigue. During winter, upon feeling ill, I took a hefty dose three times a day and was pleasantly surprised that the usual cold did not develop as it typically would over four days. I'm very satisfied and will be ordering more. The tablets are large, and I find them difficult to swallow, but the results have been worth it.
9
Eases nausea
While treating anemia, I used vitamin C to enhance the absorption of iron supplements, which was a relief since iron tablets typically induce nausea. I'm grateful for this remedy.
9
Supports absorption
I take 4000mg of vitamin C daily, spacing the doses an hour apart. Vitamin C is crucial for boosting immunity and helps absorb iron, essential for those of us with anemia. It also supports collagen synthesis and provides antioxidant benefits. This high-dose C-1000 supplement is particularly beneficial for my increased Vitamin C needs.
7
Vitamin C enhances iron absorption
Vitamin C-Rich Guava Consumed with Mungbean Dal Reduces Anemia and Increases Hemoglobin but not Iron Stores: A Randomized Controlled Trial of Food-to-Food Fortification in Indian Children.
We conducted a study to explore the impact of adding vitamin C-rich guava to a traditional meal of mungbean dal on children’s anemia in rural India. Our randomized controlled trial involved 200 school-aged children, many of whom were found to be anemic and iron-deficient. We aimed to see if this simple addition could improve their hemoglobin levels and overall iron status.
The children in our study were divided into two groups. One group enjoyed a meal of mungbean dal alone, while the other had the same meal but with fresh guava included. Our findings revealed that the addition of guava, packed with vitamin C, significantly increased hemoglobin levels and reduced anemia in the children consuming the fortified meal.
However, despite these positive outcomes in hemoglobin, we observed that body iron stores did not increase significantly. This suggests that while vitamin C can enhance iron absorption, the combination may not provide enough iron to boost overall iron storage in the body. Thus, enriching meals with vitamin C-rich foods like guava is a promising strategy to combat anemia among children.
8
Fortified beverage impacts anemia study
Pearl millet instant beverage powder enriched with baobab pulp to improve iron and anaemia status of adolescent girls in rural Ghana: a study protocol for a cluster randomised controlled trial.
We explored the impact of a fortified beverage made from pearl millet and baobab pulp on the iron and anemia status of adolescent girls in rural Ghana. This was done through a cluster randomized controlled trial involving 258 participants. Girls were divided into three groups: one that received the fortified beverage, one that received an unfortified version, and another that got standard iron and folate supplements.
Importantly, the fortified beverage contained vitamin C, which is known to enhance iron absorption. However, the study didn't isolate the effects of vitamin C alone on anemia. Therefore, while we observed the positive potential of this fortified beverage, we can't definitively conclude that vitamin C had a direct impact.
Overall, the research aims to fill a gap in understanding how food-fortification strategies can fight iron deficiency anemia, which is a significant public health issue in this region. It’s exciting to think about how these findings might influence future dietary interventions for adolescent girls facing anemia.
9
Nano-Bhasma enhances iron absorption
Advancements in Nano-Mandoor Bhasma: Unravelling the Particle Size-Ascorbic Acid Synergy for Enhanced Iron Bioavailability for Anemia Treatment.
We investigated how modifying Mandoor Bhasma, a traditional Ayurvedic medicine, could enhance its effectiveness in treating iron-deficiency anemia. By grinding this medicine into nanoparticles and coating them with ascorbic acid, we aimed to boost the iron bioavailability in our body.
In our study, we found that the surface-enhanced nano-Mandoor Bhasma exhibited better iron dissolution in conditions similar to those found in our intestines. This improvement was significant because it means that more iron becomes available for our bodies to absorb. Testing the effects on human colon cells revealed that cells treated with the modified version absorbed three times more iron compared to those treated with the standard version.
Furthermore, as the treated cells produced higher levels of a key protein related to iron storage, this signals an increase in the iron available for our body’s needs. Ultimately, this research suggests that using nanoscale formulations and vitamin C can significantly enhance the effectiveness of traditional iron treatments for anemia.
4
Vitamin C's role in anemia management
Efficacy of vitamin C on chemotherapy-related anemia in pancreatic cancer: study protocol for a randomized controlled trial.
We designed a study to examine how vitamin C affects anemia for patients undergoing chemotherapy for advanced pancreatic cancer. A total of at least 100 individuals with advanced pancreatic adenocarcinoma were recruited for a randomized trial. Some participants received standard chemotherapy, while others received the same chemotherapy alongside low-dose vitamin C.
Our main goal was to assess the rate of anemia among these patients. Additionally, we looked at the incidence of neuropathy, changes in pain levels, quality of life, and overall survival as part of our secondary endpoints.
While we expect that vitamin C might help alleviate some of the harsh side effects of chemotherapy, including anemia, our study is particularly focused on seeing if these patients will benefit from adding vitamin C to their treatment regimen. This is important because, despite the potential advantages, such as improving iron absorption and reducing fatigue, studies specifically examining these effects in pancreatic cancer patients have yet to be conducted.
8
Iron's role in resolving anemia
Effect of the treatment of iron deficiency anemia on chronic drug-resistant cough: a rare case report.
We observed a case where a 53-year-old woman suffered from a chronic, non-productive cough that didn't respond to specific treatments. After thorough examinations, she was found to have hypochromic microcytic anemia, characterized by low hemoglobin levels.
The treatment involved an oral nutraceutical capsule containing elemental iron, along with folic acid and vitamin C. Remarkably, her cough resolved after six months of this regimen. While vitamin C was part of the treatment, the significant focus was on iron, which is crucial for addressing anemia.
Therefore, while we can note the inclusion of vitamin C, its individual impact remains unclear due to the combination with iron and other vitamins. We conclude that ensuring adequate iron levels may help resolve symptoms like unexplained chronic cough tied to anemia.
9
Vitamin C boosts iron absorption
Preparation, characterization, and bioavailability evaluation of antioxidant phosvitin peptide-ferrous complex.
We investigated how vitamin C can affect anemia, particularly through its interaction with a specific iron supplement called phosvitin peptide-ferrous complex. This complex is designed to enhance iron bioavailability, which is crucial in addressing iron deficiency anemia (IDA). Our analysis showed that when vitamin C was added to this complex, there was a notable increase in iron absorption.
The results indicated that the iron content increased significantly with the presence of vitamin C, which interacted synergistically to boost bioavailability. In fact, when vitamin C was added, the iron dialysis percentage increased, highlighting its potential role in improving the efficiency of iron absorption in the gut.
While our findings suggested significant benefits in enhancing iron absorption when combined with vitamin C, it's essential to recognize that the isolated effects of vitamin C on anemia were not fully evaluated in this study. Therefore, while the combination exhibited promising results, we can't definitively say that vitamin C alone provides a solution for anemia.
References
Rani V, Moretti D, Khetarpaul N, Thankachan P, Zimmermann MB, et al. Vitamin C-Rich Guava Consumed with Mungbean Dal Reduces Anemia and Increases Hemoglobin but not Iron Stores: A Randomized Controlled Trial of Food-to-Food Fortification in Indian Children. J Nutr. 2024;154:3740. doi:10.1016/j.tjnut.2024.10.042
Atosona A, Larbie C, Apprey C, Annan RA. Pearl millet instant beverage powder enriched with baobab pulp to improve iron and anaemia status of adolescent girls in rural Ghana: a study protocol for a cluster randomised controlled trial. Br J Nutr. 2024;132:565. doi:10.1017/S0007114524001430
Wang X, Zhu X, Liu Y, Liu H, Xiao Z, et al. Efficacy of vitamin C on chemotherapy-related anemia in pancreatic cancer: study protocol for a randomized controlled trial. Trials. 2024;25:512. doi:10.1186/s13063-024-08345-w
Balkrishna A, Bhattacharya K, Samanta HS, Tomer M, Varshney A. Advancements in Nano-Mandoor Bhasma: Unravelling the Particle Size-Ascorbic Acid Synergy for Enhanced Iron Bioavailability for Anemia Treatment. Biol Trace Elem Res. 2024. doi:10.1007/s12011-024-04304-3
Gvozdenko A, Blinov A, Golik A, Rekhman Z, Nagdalian A, et al. Harnessing the Power of a Novel Triple Chelate Complex in Fermented Probiotic Dairy Products: A Promising Solution for Combating Iron Deficiency Anemia. ACS Omega. 2024;9:28594. doi:10.1021/acsomega.4c02664
Akbari F, Vahedi Larijani L, Rajabi Visroodi E, Hakiminia B. Effect of the treatment of iron deficiency anemia on chronic drug-resistant cough: a rare case report. Daru. 2024;32:967. doi:10.1007/s40199-024-00522-1
Haile A, Mara S, Belete Y, Dejene T. The Forgotten Disease in the 21st Century: Scurvy Outbreak in Hawassa Central Prison, Hawassa, Sidama, Southern Ethiopia, 2023. Int Med Case Rep J. 2023;16:847. doi:10.2147/IMCRJ.S438833
Song L, Zhu L, Qiao S, Song L, Zhang M, et al. Preparation, characterization, and bioavailability evaluation of antioxidant phosvitin peptide-ferrous complex. J Sci Food Agric. 2024;104:3090. doi:10.1002/jsfa.13200