Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 24 Researches
8
USERS' SCORE
Moderately Good
Based on 4 Reviews
7.9
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Proprietary Probiotic BlendProviding 1 billion CFU:Bifidobacterium longum BB536, B. bifidum/lactis Bb-02™, B. breve M-16V, B. infantis M-63
15 mg
**
Top Medical Research Studies
9
Bifidobacterium lactis alleviates bloating
We conducted a study to see if a fermented dairy product with Bifidobacterium lactis DN-173 010 could help reduce bloating in patients with irritable bowel syndrome (IBS) and constipation. In a controlled trial with 34 participants over four weeks, we found that this probiotic significantly decreased abdominal girth and improved gastrointestinal transit times.
Patients reported feeling less bloated, and symptom severity also decreased. These findings suggest that fostering faster transit times may be an effective method to combat abdominal distension.
Patients reported feeling less bloated, and symptom severity also decreased. These findings suggest that fostering faster transit times may be an effective method to combat abdominal distension.
Read More
9
Bifidobacterium bifidum improves bloating
Our study focused on how Bifidobacterium bifidum MIMBb75 affects bloating in patients with irritable bowel syndrome (IBS). We conducted a double-blind trial with 122 participants, half receiving MIMBb75 and half a placebo over four weeks.
The results showed that MIMBb75 significantly reduced bloating and other IBS symptoms, improving overall quality of life. About 47% of participants taking MIMBb75 reported adequate relief, compared to only 11% in the placebo group.
This makes MIMBb75 a promising option for those struggling with IBS and bloating.
The results showed that MIMBb75 significantly reduced bloating and other IBS symptoms, improving overall quality of life. About 47% of participants taking MIMBb75 reported adequate relief, compared to only 11% in the placebo group.
This makes MIMBb75 a promising option for those struggling with IBS and bloating.
Read More
8
Probiotic reduces bloating post-surgery
We explored the impact of Bifidobacterium LPL-RH on postoperative gastrointestinal symptoms in patients with valvular heart disease. In a randomized controlled trial involving 110 patients, those receiving the probiotic experienced a significant reduction in bloating compared to the placebo group. Not only did LPL-RH effectively ease bloating and abdominal pain, but it also helped improve bowel function recovery and nutritional indexes. This promising result reinforces the potential of probiotics to enhance patient recovery after heart surgery.
Read More
Most Useful Reviews
9
IBS relief
1 people found this helpful
Got what I wanted. I love this product as it effectively helps with my IBS, reducing bloating and gas.
Read More
9
Digestion improved
16 people found this helpful
Great Supplement. After taking these daily for a couple of months, I've witnessed positive results. With a history of IBS and digestive challenges, every tweak to my nutrition previously resulted in constipation, bloating, or other issues. However, this supplement has significantly improved my digestion, easing my adjustments without the usual challenges. I'm pleased with the price I found at a local health food shop, and I plan on taking these permanently.
Read More
2
Not suitable
5 people found this helpful
Not for Me. I tried these as an alternative during a stock shortage of my usual Enzymics. Unfortunately, within three days, I experienced intestinal cramping, bloating, and constipation. Switching back to my original product restored my normalcy. It's puzzling that such discrepancies exist within the same brand.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 24 Researches
8
- All Researches
9
We examined how probiotics, specifically Bifidobacterium bifidum, can help ease bloating and other symptoms of irritable bowel syndrome (IBS). Our study reviewed 18 articles, indicating that one dose of Bifidobacterium bifidum (1 × 10 CFU/day) over four weeks showed the most promise in alleviating gut-related issues.
Combining Bifidobacterium with two Lactobacillus strains and one Streptococcus strain boosted effectiveness even further. However, further clinical trials are necessary to fully confirm these findings and understand the best treatment options.
Combining Bifidobacterium with two Lactobacillus strains and one Streptococcus strain boosted effectiveness even further. However, further clinical trials are necessary to fully confirm these findings and understand the best treatment options.
Read More
9
Bifidobacterium bifidum improves bloating
Our study focused on how Bifidobacterium bifidum MIMBb75 affects bloating in patients with irritable bowel syndrome (IBS). We conducted a double-blind trial with 122 participants, half receiving MIMBb75 and half a placebo over four weeks.
The results showed that MIMBb75 significantly reduced bloating and other IBS symptoms, improving overall quality of life. About 47% of participants taking MIMBb75 reported adequate relief, compared to only 11% in the placebo group.
This makes MIMBb75 a promising option for those struggling with IBS and bloating.
The results showed that MIMBb75 significantly reduced bloating and other IBS symptoms, improving overall quality of life. About 47% of participants taking MIMBb75 reported adequate relief, compared to only 11% in the placebo group.
This makes MIMBb75 a promising option for those struggling with IBS and bloating.
Read More
We conducted a rigorous study to see how probiotic CECT 7347 (ES1) and its heat-treated version (HT-ES1) could help adults with diarrhea-predominant irritable bowel syndrome (IBS-D).
With 200 participants, we divided them into three groups, administering either the probiotic, the heat-treated version, or a placebo over 12 weeks.
Both ES1 and HT-ES1 showed significant improvements in symptom severity compared to placebo, making them promising options for those seeking relief from IBS-D symptoms.
With 200 participants, we divided them into three groups, administering either the probiotic, the heat-treated version, or a placebo over 12 weeks.
Both ES1 and HT-ES1 showed significant improvements in symptom severity compared to placebo, making them promising options for those seeking relief from IBS-D symptoms.
Read More
9
We examined the impact of Bifidobacterium longum BB536 combined with Lactobacillus rhamnosus HN001 on bloating in individuals with irritable bowel syndrome (IBS). In a controlled trial with 25 participants, we found that those treated with this probiotic formulation experienced a significant reduction in bloating, with a 36.35% decrease compared to an increase of 7.35% in the placebo group.
The treatment also led to improvements in abdominal pain and overall disease severity, pointing to its potential as an effective therapy for IBS symptoms.
The treatment also led to improvements in abdominal pain and overall disease severity, pointing to its potential as an effective therapy for IBS symptoms.
Read More
9
Bifidobacterium lactis reduces bloating
We explored whether consuming a fermented milk product with Bifidobacterium lactis could help reduce bloating and other digestive symptoms. After combining data from two studies, 538 participants reported a noticeable decrease in symptoms within just two weeks.
Notably, this improvement in digestive health appeared to happen regardless of participants' dietary fiber intake or physical activity levels. This rapid response could make it easier for individuals to stick with this dietary change for better gut health.
Notably, this improvement in digestive health appeared to happen regardless of participants' dietary fiber intake or physical activity levels. This rapid response could make it easier for individuals to stick with this dietary change for better gut health.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 4 Reviews
7.9
- All Reviews
- Positive Reviews
- Negative Reviews
9
IBS relief
1 people found this helpful
Got what I wanted. I love this product as it effectively helps with my IBS, reducing bloating and gas.
Read More
9
Digestion improved
16 people found this helpful
Great Supplement. After taking these daily for a couple of months, I've witnessed positive results. With a history of IBS and digestive challenges, every tweak to my nutrition previously resulted in constipation, bloating, or other issues. However, this supplement has significantly improved my digestion, easing my adjustments without the usual challenges. I'm pleased with the price I found at a local health food shop, and I plan on taking these permanently.
Read More
2
Not suitable
5 people found this helpful
Not for Me. I tried these as an alternative during a stock shortage of my usual Enzymics. Unfortunately, within three days, I experienced intestinal cramping, bloating, and constipation. Switching back to my original product restored my normalcy. It's puzzling that such discrepancies exist within the same brand.
Read More
6
Positive reaction noted
48 people found this helpful
Candida. I cannot ascertain whether it's an individual item or the combination that aids me, but my extensive research into chronic constipation, concentration issues, inability to lose weight, severe bloating, and sudden alarming food reactions led me to consider candidiasis. A doctor suggested it may not be candidiasis and focused on my weight instead. I preferred a simple spit test for candida overgrowth over his advice. Alternative remedies like oregano oil and probiotics were suggested, giving me a remarkable boost initially, although I also experienced some lows. My hair loss stopped, I finally lost a few pounds, and I'm finding relief from bloating and other ailments that plagued me for two years. The journey continues, but I'm moving from desperation to hopeful comfort.
Read More
Frequently Asked Questions
9
We examined how probiotics, specifically Bifidobacterium bifidum, can help ease bloating and other symptoms of irritable bowel syndrome (IBS). Our study reviewed 18 articles, indicating that one dose of Bifidobacterium bifidum (1 × 10 CFU/day) over four weeks showed the most promise in alleviating gut-related issues.
Combining Bifidobacterium with two Lactobacillus strains and one Streptococcus strain boosted effectiveness even further. However, further clinical trials are necessary to fully confirm these findings and understand the best treatment options.
Combining Bifidobacterium with two Lactobacillus strains and one Streptococcus strain boosted effectiveness even further. However, further clinical trials are necessary to fully confirm these findings and understand the best treatment options.
8
We examined the effects of a multispecies probiotic blend on bloating in patients with irritable bowel syndrome (IBS). In a randomized, double-blind study with 49 participants, those taking the probiotics reported a significant reduction in IBS symptoms, including bloating, compared to those on a placebo. By the end of the study, 68% of the probiotic group experienced notable symptom relief, while only 37.5% in the placebo group did. Overall, our findings suggest that probiotics, including Bifidobacterium bifidum, can positively impact bloating for individuals with IBS.
8
Bifidobacterium longum reduces bloating
We aimed to understand how the probiotic Bifidobacterium longum W11 affects bloating in patients with constipation-type irritable bowel syndrome (IBS). In this open study with 636 participants, we found that after 36 days of treatment, bloating significantly decreased, especially among those with moderate to severe symptoms.
Notably, bloating symptom frequency dropped dramatically, showing that this probiotic could help alleviate discomfort.
Additionally, we observed improvements in stool frequency, further indicating potential benefits for IBS patients.
Notably, bloating symptom frequency dropped dramatically, showing that this probiotic could help alleviate discomfort.
Additionally, we observed improvements in stool frequency, further indicating potential benefits for IBS patients.
8
We explored the effectiveness of Bifidobacterium lactis treatments for children suffering from irritable bowel syndrome (IBS). In a randomized controlled trial involving 71 kids aged 4 to 16, we found that both synbiotics and probiotics significantly reduced bloating and other IBS symptoms compared to prebiotics alone over four weeks.
Notably, synbiotics, which combine probiotics with inulin, led to a higher full recovery rate. Our findings suggest that using synbiotics twice daily may be a promising approach to help relieve IBS symptoms in children.
Notably, synbiotics, which combine probiotics with inulin, led to a higher full recovery rate. Our findings suggest that using synbiotics twice daily may be a promising approach to help relieve IBS symptoms in children.
9
We examined the impact of Bifidobacterium longum BB536 combined with Lactobacillus rhamnosus HN001 on bloating in individuals with irritable bowel syndrome (IBS). In a controlled trial with 25 participants, we found that those treated with this probiotic formulation experienced a significant reduction in bloating, with a 36.35% decrease compared to an increase of 7.35% in the placebo group.
The treatment also led to improvements in abdominal pain and overall disease severity, pointing to its potential as an effective therapy for IBS symptoms.
The treatment also led to improvements in abdominal pain and overall disease severity, pointing to its potential as an effective therapy for IBS symptoms.
References
- Ruiz-Sánchez C, Escudero-López B, Fernández-Pachón MS. Evaluation of the efficacy of probiotics as treatment in irritable bowel syndrome. Endocrinol Diabetes Nutr (Engl Ed). 2024;71:19. 10.1016/j.endien.2024.01.003
- Yoon JS, Sohn W, Lee OY, Lee SP, Lee KN, et al. Effect of multispecies probiotics on irritable bowel syndrome: a randomized, double-blind, placebo-controlled trial. J Gastroenterol Hepatol. 2014;29:52. 10.1111/jgh.12322
- Guglielmetti S, Mora D, Gschwender M, Popp K. Randomised clinical trial: Bifidobacterium bifidum MIMBb75 significantly alleviates irritable bowel syndrome and improves quality of life--a double-blind, placebo-controlled study. Aliment Pharmacol Ther. 2011;33:1123. 10.1111/j.1365-2036.2011.04633.x
- Tanashat M, Abuelazm M, Abouzid M, Al-Ajlouni YA, Ramadan A, et al. Efficacy of probiotics regimens for Helicobacter pylori eradication: A systematic review, pairwise, and network meta-analysis of randomized controlled trials. Clin Nutr ESPEN. 2025;65:424. 10.1016/j.clnesp.2024.11.016
- Srivastava S, Basak U, Naghibi M, Vijayakumar V, Parihar R, et al. A randomized double-blind, placebo-controlled trial to evaluate the safety and efficacy of live CECT 7347 (ES1) and heat-treated CECT 7347 (HT-ES1) in participants with diarrhea-predominant irritable bowel syndrome. Gut Microbes. 2024;16:2338322. 10.1080/19490976.2024.2338322
- Lenoir M, Wienke J, Fardao-Beyler F, Roese N. An 8-Week Course of Bifidobacterium longum 35624 Is Associated with a Reduction in the Symptoms of Irritable Bowel Syndrome. Probiotics Antimicrob Proteins. 2025;17:315. 10.1007/s12602-023-10151-w
- Miyoshi M, Kadoguchi H, Usami M, Hori Y. Synbiotics Improved Stool Form via Changes in the Microbiota and Short-Chain Fatty Acids in Hemodialysis Patients. Kobe J Med Sci. 2021;67:E112.
- Zhang C, Jiang J, Tian F, Zhao J, Zhang H, et al. Meta-analysis of randomized controlled trials of the effects of probiotics on functional constipation in adults. Clin Nutr. 2020;39:2960. 10.1016/j.clnu.2020.01.005
- Bonfrate L, Di Palo DM, Celano G, Albert A, Vitellio P, et al. Effects of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001 in IBS patients. Eur J Clin Invest. 2020;50:e13201. 10.1111/eci.13201
- Wang MC, Zaydi AI, Lin WH, Lin JS, Liong MT, et al. Putative Probiotic Strains Isolated from Kefir Improve Gastrointestinal Health Parameters in Adults: a Randomized, Single-Blind, Placebo-Controlled Study. Probiotics Antimicrob Proteins. 2020;12:840. 10.1007/s12602-019-09615-9
- Vitellio P, Celano G, Bonfrate L, Gobbetti M, Portincasa P, et al. Effects of and on Gut Microbiota in Patients with Lactose Intolerance and Persisting Functional Gastrointestinal Symptoms: A Randomised, Double-Blind, Cross-Over Study. Nutrients. 2019;11. 10.3390/nu11040886
- Chen JC, Lee WJ, Tsou JJ, Liu TP, Tsai PL. Effect of probiotics on postoperative quality of gastric bypass surgeries: a prospective randomized trial. Surg Obes Relat Dis. 2016;12:57. 10.1016/j.soard.2015.07.010
- Colecchia A, Vestito A, La Rocca A, Pasqui F, Nikiforaki A, et al. Effect of a symbiotic preparation on the clinical manifestations of irritable bowel syndrome, constipation-variant. Results of an open, uncontrolled multicenter study. Minerva Gastroenterol Dietol. 2006;52:349.
- Lan W, Yang H, Zhong Z, Luo C, Huang Q, et al. subsp. LPL-RH improves postoperative gastrointestinal symptoms and nutrition indexes by regulating the gut microbiota in patients with valvular heart disease: a randomized controlled trial. Food Funct. 2024;15:7605. 10.1039/d4fo01471e
- Vorobieva OA, Shih EV, Drozdov VN, Shikh NV. [The results of the use of a combined probiotic ( and spp. ВB-12) in children with gastrointestinal and skin manifestations of food allergy]. Vopr Pitan. 2023;92:79. 10.33029/0042-8833-2023-92-3-79-86
- Şahin K, Şahintürk Y, Köker G, Özçelik Köker G, Bostan F, et al. Metformin with Versus without Concomitant Probiotic Therapy in Newly Diagnosed Patients with Type 2 Diabetes or Prediabetes: A Comparative Analysis in Relation to Glycemic Control, Gastrointestinal Side Effects, and Treatment Compliance. Turk J Gastroenterol. 2022;33:925. 10.5152/tjg.2022.211063
- Shin CM, Choi YJ, Lee DH, Moon JS, Kim TY, et al. Validity and safety of ID-JPL934 in lower gastrointestinal symptom improvement. Sci Rep. 2021;11:13046. 10.1038/s41598-021-92007-3
- Marteau P, Le Nevé B, Quinquis L, Pichon C, Whorwell PJ, et al. Consumption of a Fermented Milk Product Containing CNCM I-2494 in Women Complaining of Minor Digestive Symptoms: Rapid Response Which Is Independent of Dietary Fibre Intake or Physical Activity. Nutrients. 2019;11. 10.3390/nu11010092
- Baştürk A, Artan R, Yılmaz A. Efficacy of synbiotic, probiotic, and prebiotic treatments for irritable bowel syndrome in children: A randomized controlled trial. Turk J Gastroenterol. 2016;27:439. 10.5152/tjg.2016.16301
- Ringel-Kulka T, Palsson OS, Maier D, Carroll I, Galanko JA, et al. Probiotic bacteria Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07 versus placebo for the symptoms of bloating in patients with functional bowel disorders: a double-blind study. J Clin Gastroenterol. 2011;45:518. 10.1097/MCG.0b013e31820ca4d6
- Nova E, Viadel B, Wärnberg J, Carreres JE, Marcos A. Beneficial effects of a synbiotic supplement on self-perceived gastrointestinal well-being and immunoinflammatory status of healthy adults. J Med Food. 2011;14:79. 10.1089/jmf.2008.0328
- Del Piano M, Carmagnola S, Anderloni A, Andorno S, Ballarè M, et al. The use of probiotics in healthy volunteers with evacuation disorders and hard stools: a double-blind, randomized, placebo-controlled study. J Clin Gastroenterol. 2010;44 Suppl 1:S30. 10.1097/MCG.0b013e3181ee31c3
- Agrawal A, Houghton LA, Morris J, Reilly B, Guyonnet D, et al. Clinical trial: the effects of a fermented milk product containing Bifidobacterium lactis DN-173 010 on abdominal distension and gastrointestinal transit in irritable bowel syndrome with constipation. Aliment Pharmacol Ther. 2009;29:104. 10.1111/j.1365-2036.2008.03853.x
- Guyonnet D, Chassany O, Ducrotte P, Picard C, Mouret M, et al. Effect of a fermented milk containing Bifidobacterium animalis DN-173 010 on the health-related quality of life and symptoms in irritable bowel syndrome in adults in primary care: a multicentre, randomized, double-blind, controlled trial. Aliment Pharmacol Ther. 2007;26:475.
