5/29/2025
Last update
5/29/2025
Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
USERS' SCORE
Good
Based on 1 Review
8.4
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
7
Vitamin E (as dl-Alpha tocopheryl acetate)
68 mg
453%
Coenzyme Q10
100 mg
**
Top Medical Research Studies
8
Q10 reduces heat stress-induced anxiety
We explored the effects of coenzyme Q10 (Q10) on anxiety symptoms caused by heat stress in male mice. The study involved several groups of mice, exposing them to high temperatures while treating them with either Q10, vitamin E, or a combination of both for two weeks. We assessed their mood through various tests that measure anxiety and despair behavior, including the forced swimming test and the elevated plus maze.
Our findings indicated that both Q10 and vitamin E had significant anxiolytic traits on the mice affected by heat stress. This means that these treatments effectively reduced anxiety levels. Not only did they show positive changes in behavior during the anxiety tests, but we also observed a notable decrease in stress hormone levels. Additionally, the treatments seemed to lower inflammatory markers in the brain, suggesting a possible pathway for their effectiveness.
In summary, incorporating Q10 into treatment strategies could offer an innovative way to address anxiety, especially in situations involving environmental stressors like extreme heat. We advocate further investigation into how these findings might translate into human applications, particularly for managing stress-induced anxiety.
Our findings indicated that both Q10 and vitamin E had significant anxiolytic traits on the mice affected by heat stress. This means that these treatments effectively reduced anxiety levels. Not only did they show positive changes in behavior during the anxiety tests, but we also observed a notable decrease in stress hormone levels. Additionally, the treatments seemed to lower inflammatory markers in the brain, suggesting a possible pathway for their effectiveness.
In summary, incorporating Q10 into treatment strategies could offer an innovative way to address anxiety, especially in situations involving environmental stressors like extreme heat. We advocate further investigation into how these findings might translate into human applications, particularly for managing stress-induced anxiety.
Read More
7
We explored the potential of coenzyme Q10 (Q10) in alleviating anxiety and depression in a mouse model of Alzheimer's disease. The study involved APPswe/PS1dE9 mice that received either Q10 or a combination of Q10 and low-intensity pulsed ultrasound (LIPUS). The latter approach aimed to enhance the delivery of Q10 through the blood-brain barrier, which is crucial since many treatments struggle to reach the brain effectively.
Our findings indicated that combining Q10 with LIPUS significantly improved anxiety-like and depression-like behaviors in these mice compared to Q10 alone. With the optimal intensity of LIPUS, the treatment led to increased levels of serotonin and dopamine in the brain, while also reducing harmful substances like formaldehyde and protein plaques associated with Alzheimer’s.
However, we must note that despite these encouraging results, the effectiveness of the LIPUS treatment, particularly at varying intensities, only partially addressed anxiety and memory issues. Thus, while this combination therapy holds promise, it is clear that more research is necessary to understand how Q10 alone impacts anxiety effectively, especially without the influence of LIPUS.
Our findings indicated that combining Q10 with LIPUS significantly improved anxiety-like and depression-like behaviors in these mice compared to Q10 alone. With the optimal intensity of LIPUS, the treatment led to increased levels of serotonin and dopamine in the brain, while also reducing harmful substances like formaldehyde and protein plaques associated with Alzheimer’s.
However, we must note that despite these encouraging results, the effectiveness of the LIPUS treatment, particularly at varying intensities, only partially addressed anxiety and memory issues. Thus, while this combination therapy holds promise, it is clear that more research is necessary to understand how Q10 alone impacts anxiety effectively, especially without the influence of LIPUS.
Read More
Most Useful Reviews
7.5
Energiser and relief
This product serves as my energiser and relieves my stress. I highly recommend it to anyone experiencing anxiety and lack of energy.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
- All Researches
8
Q10 reduces heat stress-induced anxiety
We explored the effects of coenzyme Q10 (Q10) on anxiety symptoms caused by heat stress in male mice. The study involved several groups of mice, exposing them to high temperatures while treating them with either Q10, vitamin E, or a combination of both for two weeks. We assessed their mood through various tests that measure anxiety and despair behavior, including the forced swimming test and the elevated plus maze.
Our findings indicated that both Q10 and vitamin E had significant anxiolytic traits on the mice affected by heat stress. This means that these treatments effectively reduced anxiety levels. Not only did they show positive changes in behavior during the anxiety tests, but we also observed a notable decrease in stress hormone levels. Additionally, the treatments seemed to lower inflammatory markers in the brain, suggesting a possible pathway for their effectiveness.
In summary, incorporating Q10 into treatment strategies could offer an innovative way to address anxiety, especially in situations involving environmental stressors like extreme heat. We advocate further investigation into how these findings might translate into human applications, particularly for managing stress-induced anxiety.
Our findings indicated that both Q10 and vitamin E had significant anxiolytic traits on the mice affected by heat stress. This means that these treatments effectively reduced anxiety levels. Not only did they show positive changes in behavior during the anxiety tests, but we also observed a notable decrease in stress hormone levels. Additionally, the treatments seemed to lower inflammatory markers in the brain, suggesting a possible pathway for their effectiveness.
In summary, incorporating Q10 into treatment strategies could offer an innovative way to address anxiety, especially in situations involving environmental stressors like extreme heat. We advocate further investigation into how these findings might translate into human applications, particularly for managing stress-induced anxiety.
Read More
7
We explored the potential of coenzyme Q10 (Q10) in alleviating anxiety and depression in a mouse model of Alzheimer's disease. The study involved APPswe/PS1dE9 mice that received either Q10 or a combination of Q10 and low-intensity pulsed ultrasound (LIPUS). The latter approach aimed to enhance the delivery of Q10 through the blood-brain barrier, which is crucial since many treatments struggle to reach the brain effectively.
Our findings indicated that combining Q10 with LIPUS significantly improved anxiety-like and depression-like behaviors in these mice compared to Q10 alone. With the optimal intensity of LIPUS, the treatment led to increased levels of serotonin and dopamine in the brain, while also reducing harmful substances like formaldehyde and protein plaques associated with Alzheimer’s.
However, we must note that despite these encouraging results, the effectiveness of the LIPUS treatment, particularly at varying intensities, only partially addressed anxiety and memory issues. Thus, while this combination therapy holds promise, it is clear that more research is necessary to understand how Q10 alone impacts anxiety effectively, especially without the influence of LIPUS.
Our findings indicated that combining Q10 with LIPUS significantly improved anxiety-like and depression-like behaviors in these mice compared to Q10 alone. With the optimal intensity of LIPUS, the treatment led to increased levels of serotonin and dopamine in the brain, while also reducing harmful substances like formaldehyde and protein plaques associated with Alzheimer’s.
However, we must note that despite these encouraging results, the effectiveness of the LIPUS treatment, particularly at varying intensities, only partially addressed anxiety and memory issues. Thus, while this combination therapy holds promise, it is clear that more research is necessary to understand how Q10 alone impacts anxiety effectively, especially without the influence of LIPUS.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Energiser and relief
This product serves as my energiser and relieves my stress. I highly recommend it to anyone experiencing anxiety and lack of energy.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Luo Q, Ye X, Xu J, Sun Z, Wang P, et al. Low-intensity pulsed ultrasound enhances delivery of 30 nm Q10 for improving mental and memory disorder in APP/PS1 mice. Drug Deliv Transl Res. 2025. 10.1007/s13346-025-01814-y
- Mahmoudi J, Kazmi S, Vatandoust S, Athari SZ, Sadigh-Eteghad S, et al. Coenzyme Q10 and vitamin E alleviate heat stress-induced mood disturbances in male mice: Modulation of inflammatory pathways and the HPA axis. Behav Brain Res. 2025;476:115259. 10.1016/j.bbr.2024.115259
