This study aimed to understand how dietary vitamin C affects depression in adults. By analyzing data from the National Health and Nutrition Examination Survey spanning from 2005 to 2020, we focused on the relationship between vitamin C intake and depression levels among 38,157 participants.
Our findings revealed that individuals who consumed higher amounts of vitamin C had lower odds of experiencing depression. Specifically, those in the higher intake quartiles showed significantly reduced odds compared to those with the lowest intake. Interestingly, we discovered an L-shaped curve representing the relationship between vitamin C and depression, suggesting that while increased intake was beneficial up to a certain point (around 93.61 mg), higher consumption did not yield additional benefits.
While our results are promising, it's crucial to note that this was a cross-sectional study, meaning we cannot definitively claim that vitamin C intake causes changes in depression. Additionally, other factors might have influenced these associations, which we couldn't fully control for.
Overall, this research provides intriguing evidence of the potential role that dietary vitamin C might play in alleviating depressive symptoms, especially for those consuming lower amounts.
Read More
7
SunGold kiwifruit boosts vitamin C
SunGold Kiwifruit Consumption Restores Adequate to Optimal Vitamin C Status in People with a History of Severe Respiratory Infections.
We explored whether consuming SunGold kiwifruit could help restore sufficient vitamin C levels in people who have suffered from severe respiratory infections. Over six weeks, participants consumed two kiwifruits a day, which is about 300 mg of vitamin C.
Before the study, many participants had low intakes of fruits and vegetables, and their vitamin C levels were often inadequate. After the kiwifruit intervention, we observed that around 80% of the participants managed to boost their vitamin C levels to a good range.
Notably, along with improved vitamin C status, participants reported less fatigue and fewer feelings of depression. This suggests that vitamin C might play a role in enhancing mood, although further investigation is needed to fully understand its effects.
However, about 20% of the participants still struggled to reach adequate vitamin C levels, especially those who smoked or had higher body weight. Overall, our findings indicate that adding kiwifruit to the diet may provide mood-enhancing benefits while improving vitamin C status.
Read More
8
Vitamin C and depression study
Higher serum ascorbic acid levels are associated with lower depression prevalence in US adults: a case-control study.
We explored the connection between serum ascorbic acid levels—commonly known as vitamin C—and depression in US adults. The study involved data from over 3,400 participants from the National Health and Nutrition Examination Survey. By comparing individuals diagnosed with depression to those without, we aimed to uncover whether higher vitamin C levels could be linked to lower rates of depression.
Our findings were quite revealing. We observed that individuals with depression had significantly lower serum ascorbic acid levels compared to non-depressed individuals. Specifically, the average vitamin C level in those with depression was about 43 μmol/L, while it was around 53 μmol/L for those without depression.
The research indicated a clear trend: as vitamin C levels increased, the prevalence of depression decreased. In fact, the data showed that individuals in the highest quartile of vitamin C levels had a depression prevalence of just 5.4%, compared to 12.0% in the lowest quartile.
While this correlation suggests that higher vitamin C levels might help reduce the risk of depression, it’s important to note that the study did not test vitamin C as a treatment for depression directly. Therefore, while the association is noteworthy, we cannot definitively say that vitamin C supplementation will resolve depressive symptoms.
Read More
Most Useful Reviews
9
Excellent vitamin escape
I've been taking vitamin C for three years, prompted by Dr. Tokumi Fujikawa's recommendations. Previously, I often caught colds and had a sore throat, but now I haven’t been ill for two years. This excellent vitamin has aided in alleviating my depression and functional dyspepsia, particularly relevant given my age. I comfortably take two tablets each morning and evening. Though swallowing them was tricky at first, it became easier, and now I consider it essential for immunity, especially during these times.
Read More
7.5
Overcoming depression
Vitamin C strengthens the immune system, helping the body resist infections, cleanses blood vessels, increases their elasticity, strengthens them, and removes cholesterol plaques. It positively impacts the nervous system, aiding in overcoming depression, particularly in the colder months. A large dosage is convenient, though the pills are quite big. I found 500 mg more manageable. I experienced no side effects; it’s not difficult, just beneficial!
Read More
6
Considerable improvement
4 people found this helpful
I purchased this for mothers suffering from depression and sleep disorders. While this alone isn't an improvement, I've read various books and provided some supplements, as nutrition is vital. Visiting the hospital, it's challenging to ascertain what truly works, but I've noticed considerable improvement over the year.
Vitamin C improved anxiety and depression like behavior induced by chronic unpredictable mild stress in adolescent rats by influencing on oxidative stress balance, neurotransmitter systems, and inflammatory response.
We explored the impact of vitamin C on anxiety and depression behaviors prompted by chronic unpredictable mild stress (CUMS) in adolescent male rats. The study investigated whether exposure to this type of stress during adolescence could lead to mood-related issues in adulthood, and if vitamin C could help alleviate these problems.
Our research utilized several behavioral tests to measure anxiety and depression levels. We also examined how CUMS affected serotonin metabolism, inflammation levels, oxidative stress, and brain-derived neurotrophic factor (BDNF) in the brain tissue of the rats.
Our findings indicated that CUMS indeed worsened mood-related behaviors by negatively affecting the brain's balance between oxidative stress, inflammation, and serotonin levels. However, rats that received both CUMS treatment and vitamin C showed promising results. This co-treatment helped reverse the negative effects induced by CUMS, suggesting that vitamin C may restore the disturbed biochemical parameters.
Overall, we propose that vitamin C supplementation could be a safe and effective strategy for managing stress-induced anxiety and depression.
Read More
8
Vitamin C alleviates withdrawal depression
Ascorbic acid supplementation in adolescent rats ameliorates anxiety-like and depressive-like manifestations of nicotine-ethanol abstinence: Role of oxidative stress, inflammatory, and serotonergic mechanisms.
We explored the effects of vitamin C on anxiety and depression linked to abstinence from nicotine and ethanol in adolescent male rats. The study was carefully structured, dividing the rats into several groups, including a control group and various treatment groups receiving different doses of vitamin C during the withdrawal phase.
Our results suggested that vitamin C supplementation effectively reduced anxiety- and depressive-like behaviors. This was observed through various behavioral tests, such as the elevated plus maze and forced swimming test, indicating that the rats receiving vitamin C exhibited improved mood and reduced anxiety.
Notably, vitamin C appeared to enhance the antioxidant defense system, lower inflammation, and promote serotonin levels—important factors in mood regulation. While there were many facets at play due to the combined effects of nicotine and ethanol, the positive impact of vitamin C supplementation stands out as a potential therapeutic approach for managing withdrawal symptoms.
Overall, the findings highlight vitamin C's promising role in improving mental health during challenging withdrawal periods, making it a valuable supplement for further exploration in human studies.
Read More
8
Dietary antioxidants and depression
Association between Dietary Antioxidant Capacity in Midlife and Depressive Symptoms in Late Life: The Singapore Chinese Health Study.
We examined how midlife dietary intake of antioxidants, including vitamin C, relates to depressive symptoms in older age among a large group of Chinese participants in Singapore. By analyzing data from over 13,000 individuals, we were able to see clear patterns connecting antioxidant consumption—specifically from vitamins C and E, as well as carotenoids and flavonoids—to mental health outcomes.
Participants, initially assessed at a mean age of 52, were later evaluated for depressive symptoms around age 73. The results revealed that higher intakes of antioxidants were linked with reduced odds of experiencing depression. In fact, those with the highest consumption showed significantly lower likelihoods of developing depressive symptoms.
This reinforces the importance of an antioxidant-rich diet, suggesting that such dietary choices might help in preventing depression in later life. Though we didn't isolate vitamin C's effects from the other antioxidants, its presence in a balanced diet could contribute positively to mental health.
Read More
8
Vitamin C intake linked to depression
Association of dietary vitamin C intake with depression in adults: A cross-sectional study of NHANES from 2005 to 2020.
This study aimed to understand how dietary vitamin C affects depression in adults. By analyzing data from the National Health and Nutrition Examination Survey spanning from 2005 to 2020, we focused on the relationship between vitamin C intake and depression levels among 38,157 participants.
Our findings revealed that individuals who consumed higher amounts of vitamin C had lower odds of experiencing depression. Specifically, those in the higher intake quartiles showed significantly reduced odds compared to those with the lowest intake. Interestingly, we discovered an L-shaped curve representing the relationship between vitamin C and depression, suggesting that while increased intake was beneficial up to a certain point (around 93.61 mg), higher consumption did not yield additional benefits.
While our results are promising, it's crucial to note that this was a cross-sectional study, meaning we cannot definitively claim that vitamin C intake causes changes in depression. Additionally, other factors might have influenced these associations, which we couldn't fully control for.
Overall, this research provides intriguing evidence of the potential role that dietary vitamin C might play in alleviating depressive symptoms, especially for those consuming lower amounts.
Read More
8
Vitamin C and depression study
Higher serum ascorbic acid levels are associated with lower depression prevalence in US adults: a case-control study.
We explored the connection between serum ascorbic acid levels—commonly known as vitamin C—and depression in US adults. The study involved data from over 3,400 participants from the National Health and Nutrition Examination Survey. By comparing individuals diagnosed with depression to those without, we aimed to uncover whether higher vitamin C levels could be linked to lower rates of depression.
Our findings were quite revealing. We observed that individuals with depression had significantly lower serum ascorbic acid levels compared to non-depressed individuals. Specifically, the average vitamin C level in those with depression was about 43 μmol/L, while it was around 53 μmol/L for those without depression.
The research indicated a clear trend: as vitamin C levels increased, the prevalence of depression decreased. In fact, the data showed that individuals in the highest quartile of vitamin C levels had a depression prevalence of just 5.4%, compared to 12.0% in the lowest quartile.
While this correlation suggests that higher vitamin C levels might help reduce the risk of depression, it’s important to note that the study did not test vitamin C as a treatment for depression directly. Therefore, while the association is noteworthy, we cannot definitively say that vitamin C supplementation will resolve depressive symptoms.
I've been taking vitamin C for three years, prompted by Dr. Tokumi Fujikawa's recommendations. Previously, I often caught colds and had a sore throat, but now I haven’t been ill for two years. This excellent vitamin has aided in alleviating my depression and functional dyspepsia, particularly relevant given my age. I comfortably take two tablets each morning and evening. Though swallowing them was tricky at first, it became easier, and now I consider it essential for immunity, especially during these times.
Read More
7.5
Overcoming depression
Vitamin C strengthens the immune system, helping the body resist infections, cleanses blood vessels, increases their elasticity, strengthens them, and removes cholesterol plaques. It positively impacts the nervous system, aiding in overcoming depression, particularly in the colder months. A large dosage is convenient, though the pills are quite big. I found 500 mg more manageable. I experienced no side effects; it’s not difficult, just beneficial!
Read More
6
Considerable improvement
4 people found this helpful
I purchased this for mothers suffering from depression and sleep disorders. While this alone isn't an improvement, I've read various books and provided some supplements, as nutrition is vital. Visiting the hospital, it's challenging to ascertain what truly works, but I've noticed considerable improvement over the year.
Read More
Frequently Asked Questions
Depression is a common and serious mental health condition characterized by persistent feelings of sadness, hopelessness, and a lack of interest or pleasure in activities that were once enjoyable. It can affect anyone, regardless of age, gender, or background, and it goes beyond just feeling down; it can interfere significantly with daily life, impacting relationships, work performance, and overall well-being. Symptoms of depression may include changes in appetite or weight, sleep disturbances, fatigue, difficulty concentrating, and thoughts of worthlessness or suicide.
The causes of depression are complex and may involve a combination of genetic, biological, environmental, and psychological factors. While it's a serious condition that can be debilitating, the good news is that it is treatable. Various treatment options are available, including therapy, medication, lifestyle changes, and support groups. If you or someone you know is struggling with depression, seeking help from a healthcare professional is a crucial step toward recovery.
Vitamin C, also known as ascorbic acid, is a water-soluble vitamin that plays a critical role in numerous bodily functions. As an essential nutrient, it contributes to the growth and repair of tissues in the body, and it is vital for the production of collagen, an important protein that helps maintain skin, cartilage, tendons, ligaments, and blood vessels. Additionally, Vitamin C acts as a powerful antioxidant, which means it helps combat free radicals—unstable molecules that can cause oxidative stress and contribute to various chronic diseases.
Moreover, Vitamin C enhances iron absorption from plant-based foods, making it a vital component for those following vegetarian or vegan diets. While many people get sufficient Vitamin C from a well-balanced diet that includes fruits and vegetables like oranges, strawberries, kiwi, broccoli, and bell peppers, some individuals might require supplementation. It's generally recommended to stay within the daily intake guidelines, as excessive consumption can lead to gastrointestinal disturbances. Overall, Vitamin C is not just a skincare celebrity—it's a fundamental part of maintaining overall health and well-being.
Research suggests that vitamin C may play a role in alleviating symptoms of depression, although it should not be considered a standalone treatment. Vitamin C is an essential nutrient that acts as a powerful antioxidant, helping to combat oxidative stress in the brain, which has been linked to mood disorders. Some studies indicate that individuals with lower levels of vitamin C may experience higher rates of depression, while supplementation could potentially improve mood and overall well-being. However, it's important to note that while a balanced diet rich in fruits and vegetables can contribute positively to mental health, vitamin C should complement other treatments, such as therapy or medication, rather than replace them.
If you're considering vitamin C supplementation as part of your strategy to address depression, it's wise to consult with a healthcare professional, as they can provide personalized advice and ensure that you are addressing all aspects of your mental health. Supplements are available, but the best approach is to focus on a varied diet that includes citrus fruits, berries, peppers, and leafy greens that naturally boost your vitamin C intake. While the research is promising, remember that mental health is complex, and a comprehensive approach is essential for effective management.
Based on user reviews, the timeline for seeing results from taking a vitamin C supplement for depression can vary. One user reported that after three years of consistent use, they felt significant improvement in their depression symptoms alongside other health benefits, highlighting the long-term commitment required for noticeable changes Read Review. Another review suggested a more gradual change, with one user stating that considerable improvement was observed over the course of a year, indicating that while some may notice effects sooner, others may need to wait longer to see substantial results Read Review.
Many users have emphasized the importance of combining vitamin C with other supplements and dietary adjustments, suggesting a multifaceted approach could be beneficial for managing depression Read Review. Therefore, while initial effects might be felt relatively soon, significant progress often appears over several months to years of consistent use.
While vitamin C has been associated with various aspects of mental health, the scientific evidence regarding its direct efficacy in reducing depression remains inconclusive. Several studies indicate that lower levels of vitamin C may correlate with higher risks of depressive symptoms. For instance, an analysis of data from the National Health and Nutrition Examination Survey revealed that individuals with lower serum vitamin C levels had a notable prevalence of depression, suggesting that adequate vitamin C might help in mood regulation [9]. Another study indicated that vitamin C supplementation might alleviate depressive behaviors in rats exposed to chronic stress [2]. However, the findings do not establish a definitive causal relationship between vitamin C supplementation and depression treatment.
In experimental models, there is evidence suggesting that vitamin C could enhance the effects of traditional antidepressants like escitalopram and citalopram, indicating a potential supportive role rather than a primary treatment [10], [8]. Despite these interesting findings, it's crucial to note that no studies have conclusively demonstrated that vitamin C acts as an effective standalone treatment for depression. Thus, while vitamin C shows promise in relation to mood enhancement, more comprehensive human studies are needed to validate its therapeutic benefits in managing depression directly.
Users have reported various improvements in their symptoms after taking vitamin C supplements, particularly concerning depression and overall health. One long-term user shared that they experienced a significant alleviation of depression symptoms and were able to fend off illnesses such as colds and sore throats after three years of consistent vitamin C intake, underscoring its potential role in bolstering both immune function and mental well-being Read Review. Another review highlights that vitamin C positively impacts the nervous system, particularly during cold months, contributing to better mood management and resilience against depressive episodes Read Review.
Additionally, a user noted that while vitamin C was just one part of a broader strategy—including dietary adjustments and other supplements—there was observable improvement over a year's time, which illustrates the multifaceted approach that some users advocate for when dealing with depression Read Review. It's important to remember that individual results can vary widely, with some users feeling the benefits after several months and others finding it takes a year or more.
Users have reported a range of experiences when combining vitamin C with other supplements and dietary changes to manage depression. One user specifically indicated that while vitamin C alone did not yield significant improvements, a comprehensive approach—which included additional supplements and careful attention to nutrition—showed considerable progress over the course of a year Read Review. This highlights the belief in a multifaceted strategy for treating depression, suggesting that the best results may be achieved through a combination of factors rather than relying on a single supplement.
Moreover, it's noted that vitamin C not only supports immune health but also positively influences the nervous system, potentially enhancing mood, especially during colder months Read Review. Users recommend a holistic approach that includes vitamin C along with other dietary considerations to maximize its therapeutic effects, reinforcing the idea that synergy among various supplements can create a more effective framework for managing symptoms of depression.
Users report varying experiences with Vitamin C doses for treating depression. One user, who has taken Vitamin C for three years, mentions that they comfortably consume two tablets each morning and evening, suggesting that a consistent regimen has significantly aided in alleviating their depressive symptoms Read Review. Another user found that a dose of 500 mg was more manageable, indicating that smaller doses can still provide benefits without side effects Read Review.
However, it's important to note that some users emphasize the need for a comprehensive approach to mental health, suggesting that while Vitamin C may help, it should be part of a broader strategy that includes good nutrition and possibly other supplements Read Review. Overall, users seem to find that incorporating Vitamin C into their daily routine—with preferences for different dosages—can contribute positively to managing depression.
9
Excellent vitamin escape
I've been taking vitamin C for three years, prompted by Dr. Tokumi Fujikawa's recommendations. Previously, I often caught colds and had a sore throat, but now I haven’t been ill for two years. This excellent vitamin has aided in alleviating my depression and functional dyspepsia, particularly relevant given my age. I comfortably take two tablets each morning and evening. Though swallowing them was tricky at first, it became easier, and now I consider it essential for immunity, especially during these times.
6
Considerable improvement
4 people found this helpful
I purchased this for mothers suffering from depression and sleep disorders. While this alone isn't an improvement, I've read various books and provided some supplements, as nutrition is vital. Visiting the hospital, it's challenging to ascertain what truly works, but I've noticed considerable improvement over the year.
7.5
Overcoming depression
Vitamin C strengthens the immune system, helping the body resist infections, cleanses blood vessels, increases their elasticity, strengthens them, and removes cholesterol plaques. It positively impacts the nervous system, aiding in overcoming depression, particularly in the colder months. A large dosage is convenient, though the pills are quite big. I found 500 mg more manageable. I experienced no side effects; it’s not difficult, just beneficial!
8
Vitamin C and depression study
Higher serum ascorbic acid levels are associated with lower depression prevalence in US adults: a case-control study.
We explored the connection between serum ascorbic acid levels—commonly known as vitamin C—and depression in US adults. The study involved data from over 3,400 participants from the National Health and Nutrition Examination Survey. By comparing individuals diagnosed with depression to those without, we aimed to uncover whether higher vitamin C levels could be linked to lower rates of depression.
Our findings were quite revealing. We observed that individuals with depression had significantly lower serum ascorbic acid levels compared to non-depressed individuals. Specifically, the average vitamin C level in those with depression was about 43 μmol/L, while it was around 53 μmol/L for those without depression.
The research indicated a clear trend: as vitamin C levels increased, the prevalence of depression decreased. In fact, the data showed that individuals in the highest quartile of vitamin C levels had a depression prevalence of just 5.4%, compared to 12.0% in the lowest quartile.
While this correlation suggests that higher vitamin C levels might help reduce the risk of depression, it’s important to note that the study did not test vitamin C as a treatment for depression directly. Therefore, while the association is noteworthy, we cannot definitively say that vitamin C supplementation will resolve depressive symptoms.
9
Vitamin C counters stress-related depression
Vitamin C improved anxiety and depression like behavior induced by chronic unpredictable mild stress in adolescent rats by influencing on oxidative stress balance, neurotransmitter systems, and inflammatory response.
We explored the impact of vitamin C on anxiety and depression behaviors prompted by chronic unpredictable mild stress (CUMS) in adolescent male rats. The study investigated whether exposure to this type of stress during adolescence could lead to mood-related issues in adulthood, and if vitamin C could help alleviate these problems.
Our research utilized several behavioral tests to measure anxiety and depression levels. We also examined how CUMS affected serotonin metabolism, inflammation levels, oxidative stress, and brain-derived neurotrophic factor (BDNF) in the brain tissue of the rats.
Our findings indicated that CUMS indeed worsened mood-related behaviors by negatively affecting the brain's balance between oxidative stress, inflammation, and serotonin levels. However, rats that received both CUMS treatment and vitamin C showed promising results. This co-treatment helped reverse the negative effects induced by CUMS, suggesting that vitamin C may restore the disturbed biochemical parameters.
Overall, we propose that vitamin C supplementation could be a safe and effective strategy for managing stress-induced anxiety and depression.
8
Vitamin C enhances depression treatment
Unraveling the potential of vitamins C and D as adjuvants in depression treatment with escitalopram in an LPS animal model.
We conducted an evaluation of how vitamin C might enhance the effectiveness of escitalopram, a common antidepressant, in combating depression. In our experiment, we used male Swiss albino mice subjected to a model of depression induced by lipopolysaccharide (LPS). Mice were divided into several groups, including those receiving escitalopram alone and those given a combination of escitalopram with vitamin C.
After a week of treatment, we saw promising results. The group treated with both escitalopram and vitamin C, along with vitamin D, showed a significant improvement in depressive symptoms compared to the group that received only LPS. This suggests that vitamin C, when used alongside escitalopram, may provide a beneficial boost in mood regulation.
It's important to note that while vitamin C appeared to enhance the antidepressant response, prominent sedation was observed in all treated groups, raising questions about the side effects. Additionally, we found that vitamin C helped restore levels of Brain-Derived Neurotrophic Factor (BDNF) in the hippocampus, which is crucial for brain health and mood. Overall, our findings support the idea that vitamin C could be a valuable adjunct in depression treatment, emphasizing the need for further research in this area.
7
Vitamins enhance antidepressant effects
Exploring the Roles of Vitamins C and D and Etifoxine in Combination with Citalopram in Depression/Anxiety Model: A Focus on ICAM-1, SIRT1 and Nitric Oxide.
We set out to investigate how vitamin C, along with other treatments, impacts depression and anxiety in an experimental model. To do this, we used BALB/c mice, dividing them into several groups, including a control and those receiving citalopram—the well-known antidepressant—combined with vitamin C, vitamin D, or etifoxine.
Over a week, we observed the effects of these combinations after subjecting the mice to stress tests designed to measure depression and anxiety symptoms. Our findings illustrate that adding vitamin C to citalopram enhanced its antidepressant effects, as indicated by improved behaviors in the tests we conducted. Notably, we found that vitamin C was able to modulate important biological markers related to depression, which include ICAM-1, SIRT1, and nitric oxide in the brain.
Despite the promising results from the combination treatments, our analysis suggests that vitamin C's isolated effects are still somewhat unclear since it was always combined with citalopram in our study design. Overall, vitamin C appears to play a beneficial role in managing depression when paired with citalopram, although we must delve deeper to clarify its specific contributions.
References
Najafzadeh A, Mahdizadeh M, Kakhki S, Rahimi A, Ahmadi-Soleimani SM, et al. Ascorbic acid supplementation in adolescent rats ameliorates anxiety-like and depressive-like manifestations of nicotine-ethanol abstinence: Role of oxidative stress, inflammatory, and serotonergic mechanisms. Int J Dev Neurosci. 2025;85:e10392. doi:10.1002/jdn.10392
Masoudi M, Goodarzi M, Rahmani MA, Rajabi M, Mahdizadeh M, et al. Vitamin C improved anxiety and depression like behavior induced by chronic unpredictable mild stress in adolescent rats by influencing on oxidative stress balance, neurotransmitter systems, and inflammatory response. Nutr Neurosci. 2024. doi:10.1080/1028415X.2024.2389499
Cao Q, Hong A, Chen M, Wang C, Zhu M, et al. The association between vitamin C and depressive risk based on the National Health and Nutrition Examination Survey of 2017-2018 and Mendelian randomization study. Am J Transl Res. 2024;16:5137. doi:10.62347/FXXD5655
Li H, Sheng LT, Tai BC, Pan A, Koh WP. Association between Dietary Antioxidant Capacity in Midlife and Depressive Symptoms in Late Life: The Singapore Chinese Health Study. Antioxidants (Basel). 2024;13. doi:10.3390/antiox13050576
Zhao D, Long X, Wang J. Association of dietary vitamin C intake with depression in adults: A cross-sectional study of NHANES from 2005 to 2020. J Affect Disord. 2024;358:113. doi:10.1016/j.jad.2024.05.032
Lu Z, Yang Y, Zhao G, Zhang Y, Sun Y, et al. The Association of Redox Regulatory Drug Target Genes with Psychiatric Disorders: A Mendelian Randomization Study. Antioxidants (Basel). 2024;13. doi:10.3390/antiox13040398
Vlasiuk E, Zawari M, Storer M, Maze MJ, Williman J, et al. SunGold Kiwifruit Consumption Restores Adequate to Optimal Vitamin C Status in People with a History of Severe Respiratory Infections. Antioxidants (Basel). 2024;13. doi:10.3390/antiox13030272
Gammoh O, Ibrahim A, Yehya A, Alqudah A, Qnais E, et al. Exploring the Roles of Vitamins C and D and Etifoxine in Combination with Citalopram in Depression/Anxiety Model: A Focus on ICAM-1, SIRT1 and Nitric Oxide. Int J Mol Sci. 2024;25. doi:10.3390/ijms25041960
Chen M, Luo H, Han Y, Li Y, Zhou L, et al. Higher serum ascorbic acid levels are associated with lower depression prevalence in US adults: a case-control study. Front Nutr. 2024;11:1324835. doi:10.3389/fnut.2024.1324835
Gammoh O, Akasheh RT, Qnais E, Al-Taber S, Athamneh RY, et al. Unraveling the potential of vitamins C and D as adjuvants in depression treatment with escitalopram in an LPS animal model. Inflammopharmacology. 2024;32:1147. doi:10.1007/s10787-023-01404-9