Can Solgar Advanced 40+ Acidophilus Help with Bloating?
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 33 Researches
7.7
USERS' SCORE
Good
Based on 10 Reviews
8.6
Supplement Facts
Serving Size: 1 Vegetable Capsule
Amount Per Serving
%DV
Advanced 40+ Acidophilus 1.5 billion CFUproviding:Lactobacillus. acidophilus, (LA-5®)300 million CFULactobacillus rhamnosus GG (LGG®)300 million CFULactobacillus paracasei (L. CASEI 431®)300 million CFU Bifidobacterium lactis (BB-12®)300 million CFUStreptococcus thermophilus, (TH-4®)300 million CFU
2.4 mg
**
Top Medical Research Studies
9
Bifidobacterium lactis alleviates bloating
Clinical trial: the effects of a fermented milk product containing Bifidobacterium lactis DN-173 010 on abdominal distension and gastrointestinal transit in irritable bowel syndrome with constipation.
We conducted a study to see if a fermented dairy product with Bifidobacterium lactis DN-173 010 could help reduce bloating in patients with irritable bowel syndrome (IBS) and constipation. In a controlled trial with 34 participants over four weeks, we found that this probiotic significantly decreased abdominal girth and improved gastrointestinal transit times.
Patients reported feeling less bloated, and symptom severity also decreased. These findings suggest that fostering faster transit times may be an effective method to combat abdominal distension.
Read More
9
Lactobacillus improves bloating symptoms
Probiotic bacteria Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07 versus placebo for the symptoms of bloating in patients with functional bowel disorders: a double-blind study.
We conducted a double-blind, placebo-controlled trial to assess how Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07 affect bloating in patients with functional bowel disorders.
Over eight weeks, patients reported a noticeable improvement in abdominal bloating when taking probiotics compared to those on a placebo.
Notably, results showed significant relief at four weeks and continued improvement by eight weeks, especially among those with irritable bowel syndrome. This suggests probiotics could be beneficial in managing bloating symptoms.
Read More
9
Lactobacillus acidophilus reduces bloating
[Lactobacilli in the treatment of dyspepsia due to dysmicrobia of various causes].
We examined how Lactobacillus acidophilus can help treat bloating in patients with dyspepsia due to imbalances in gut bacteria. In a study involving 30 participants, symptoms such as pain, pressure, and bloating were self-reported while objective measures like bowel movements and weight changes were also tracked.
Those affected by antibiotic-induced dysbiosis experienced rapid relief within days. Improvements were noted in symptoms of maldigestion over a week, and remarkable results were observed in patients with radiation enterocolitis. Overall, this probiotic showed promise for alleviating digestive discomfort without notable side effects.
Read More
Most Useful Reviews
9
Bloating alleviated
7 people found this helpful
Liked trying different prebiotics from our pharmacies—no effect. Thanks to these "animals," the bloated abdomen, heaviness inside, and unpleasant intestinal sensations disappeared, and my weight began to decrease. This isn't some form of advertising hype! I read about similar bacteria and took a pill each morning on an empty stomach, followed by breakfast with cereal or muesli.
Read More
7.5
Effective after adjustment
7 people found this helpful
I liked the probiotic and ordered two more cans. Initially, I experienced bloating as the probiotic seemed to be in conflict with the pathogenic microflora, leading to toxin release. However, after five days, the unpleasant sensations and bloating disappeared, and my stool improved. I recommend this probiotic—it’s effective, especially since I have much to compare it with.
Read More
9
Bloating relief
6 people found this helpful
An excellent probiotic that helped get rid of my bloating. I decided to make yogurt with it using farmer's unpasteurised milk, and it turned out quite tasty, resembling kefir, which my child enjoyed. I order several cans each winter to last until autumn. Bless you!
Probiotic bacteria Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07 versus placebo for the symptoms of bloating in patients with functional bowel disorders: a double-blind study.
We conducted a double-blind, placebo-controlled trial to assess how Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07 affect bloating in patients with functional bowel disorders.
Over eight weeks, patients reported a noticeable improvement in abdominal bloating when taking probiotics compared to those on a placebo.
Notably, results showed significant relief at four weeks and continued improvement by eight weeks, especially among those with irritable bowel syndrome. This suggests probiotics could be beneficial in managing bloating symptoms.
Read More
9
SCM-III improves IBS symptoms
Single-blind follow-up study on the effectiveness of a symbiotic preparation in irritable bowel syndrome.
We conducted a study examining the effects of a novel symbiotic treatment, SCM-III, on patients with irritable bowel syndrome (IBS). Sixty-eight adults were divided into two groups—one received SCM-III and the other a heat-inactivated version, both for 12 weeks.
Our findings showed that most patients reported significant improvements in bloating and abdominal pain compared to a control group. Over 80% felt the treatment was effective, while less than 5% labelled it ineffective.
Overall, this suggests that certain IBS patients could greatly benefit from symbiotic treatments like SCM-III, though it may require a cyclic use for best results.
Read More
9
Lactobacillus acidophilus reduces bloating
[Lactobacilli in the treatment of dyspepsia due to dysmicrobia of various causes].
We examined how Lactobacillus acidophilus can help treat bloating in patients with dyspepsia due to imbalances in gut bacteria. In a study involving 30 participants, symptoms such as pain, pressure, and bloating were self-reported while objective measures like bowel movements and weight changes were also tracked.
Those affected by antibiotic-induced dysbiosis experienced rapid relief within days. Improvements were noted in symptoms of maldigestion over a week, and remarkable results were observed in patients with radiation enterocolitis. Overall, this probiotic showed promise for alleviating digestive discomfort without notable side effects.
Read More
9
Probiotics improve allergy symptoms
[The results of the use of a combined probiotic ( and spp. ВB-12) in children with gastrointestinal and skin manifestations of food allergy].
We evaluated the effects of a combined probiotic treatment on food allergies in children aged 4 to 5. In our study, 92 children participated, where one group took probiotics containing Lactobacillus rhamnosus GG for 21 days, while the other group did not.
The children on probiotics experienced significant improvements in skin and gastrointestinal symptoms, including a decrease in bloating. Their IgE levels also dropped notably, suggesting an overall healthier immune response. The control group showed no significant changes.
Overall, lactobacillus rhamnosus proved beneficial for reducing allergy symptoms and improving gut health.
Read More
9
Lactobacillus rhamnosus reduces bloating
Effects of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001 in IBS patients.
We investigated how a combination of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001, along with vitamin B6, affects bloating in patients with irritable bowel syndrome (IBS). In a well-structured crossover trial involving 25 IBS patients, we found that this formula significantly reduced bloating by about 36% compared to a placebo. Additionally, patients experienced reduced abdominal pain and improved gut health. Overall, this treatment shows promise for alleviating IBS symptoms and enhancing gut health.
Liked trying different prebiotics from our pharmacies—no effect. Thanks to these "animals," the bloated abdomen, heaviness inside, and unpleasant intestinal sensations disappeared, and my weight began to decrease. This isn't some form of advertising hype! I read about similar bacteria and took a pill each morning on an empty stomach, followed by breakfast with cereal or muesli.
Read More
7.5
Effective after adjustment
7 people found this helpful
I liked the probiotic and ordered two more cans. Initially, I experienced bloating as the probiotic seemed to be in conflict with the pathogenic microflora, leading to toxin release. However, after five days, the unpleasant sensations and bloating disappeared, and my stool improved. I recommend this probiotic—it’s effective, especially since I have much to compare it with.
Read More
9
Bloating relief
6 people found this helpful
An excellent probiotic that helped get rid of my bloating. I decided to make yogurt with it using farmer's unpasteurised milk, and it turned out quite tasty, resembling kefir, which my child enjoyed. I order several cans each winter to last until autumn. Bless you!
Read More
9
Temporary relief
4 people found this helpful
Good pills that effectively manage my bloating, and I experience much less constipation! However, once I stop taking them, all problems promptly return the very next day, hence I give it four stars.
Read More
9
Bloating eradicated
3 people found this helpful
I tried various prebiotics from our pharmacies, which had no effect. However, thanks to these "animals," the bloated stomach, heaviness, and unpleasant intestinal sensations disappeared, and my weight started to drop. This is certainly not just advertising nonsense! I took a pill each morning on an empty stomach and had porridge or muesli for breakfast.
Bloating is a common gastrointestinal condition characterized by a sensation of fullness, tightness, or swelling in the abdomen. It often occurs after eating and can be accompanied by visible distension of the belly. This discomfort may be caused by various factors, including excessive gas production, food intolerances, overeating, or certain medical conditions affecting the digestive system. Many people experience bloating occasionally, but when it becomes chronic, it can significantly impact one's quality of life.
Managing bloating typically involves dietary adjustments, such as identifying and avoiding trigger foods, eating smaller meals, and incorporating more fiber into your diet. Staying hydrated and engaging in regular physical activity can also help alleviate symptoms. If bloating is persistent or accompanied by other troubling symptoms like severe pain or changes in bowel habits, it is advisable to consult a healthcare professional for proper evaluation and guidance.
Probiotics are live microorganisms, primarily bacteria, that are intended to provide health benefits when consumed in adequate amounts. These beneficial bacteria are often referred to as "good" or "friendly" bacteria because they help maintain a balanced gut microbiome, which plays a vital role in digestion, immune function, and overall health. Probiotics can be found in various foods such as yogurt, kefir, sauerkraut, and kombucha, as well as in dietary supplements. The most common strains include Lactobacillus and Bifidobacterium, which have been studied for their positive effects on gastrointestinal health, including the alleviation of symptoms related to irritable bowel syndrome (IBS) and diarrhea.
Incorporating probiotics into your diet may help support a healthy gut by competing with harmful bacteria and promoting a more diverse microbiome. However, it's important to note that the specific effects of probiotics can vary widely depending on the strain, dosage, and individual health conditions. While many people may benefit from including probiotics in their diet, it's advisable to consult a healthcare professional before starting any new supplement regimen, especially if you have underlying health issues or concerns. For those looking to explore the world of probiotics, it’s worth experimenting with various sources to find what works best for your body.
Probiotics may offer relief for bloating, depending on the underlying causes and individual responses. These beneficial bacteria can help restore the natural balance of gut flora, which may alleviate digestive issues, including bloating. Several studies suggest that specific strains of probiotics, like Lactobacillus and Bifidobacterium, can improve gastrointestinal health by enhancing digestion and reducing gas production. As a result, individuals experiencing bloating due to an imbalance of gut bacteria might find improvement when incorporating probiotics into their diet.
However, it's important to note that not everyone will experience the same benefits, and results can vary. Some people may need to try different probiotic strains to find one that works best for them. Additionally, bloating can stem from various dietary or medical issues, so it's advisable to consult a healthcare professional if symptoms persist. While probiotics can be a helpful part of a digestive health regimen, they should be considered alongside other lifestyle factors, such as diet and hydration, for more effective bloating relief.
Based on user reviews, the time it takes to see results from this bloating supplement can vary. Some users report noticing relief very quickly; for instance, one reviewer mentioned feeling a decrease in bloating within just one day of starting the supplement (Read Review). Others have experienced improvements over a few days, with a user noting that their uncomfortable sensations and bloating disappeared after about five days (Read Review).
However, it's essential to note that the effectiveness of the supplement can be individual. Some users felt significant relief from their bloating after consistent use, while others mentioned that symptoms returned quickly after stopping (Read Review). Overall, while quick relief within a day is possible, many users suggest that a period of several days may be typical to notice significant changes.
The effectiveness of probiotics in reducing bloating is supported by a variety of studies, showcasing their potential benefits for individuals with gastrointestinal discomfort. For instance, a comprehensive analysis involving 81 studies highlighted specific probiotic strains, such as Lactobacillus acidophilus and Bifidobacterium lactis, as effective in alleviating bloating, particularly among those diagnosed with irritable bowel syndrome (IBS) [1]. Another study demonstrated the positive impact of Lactobacillus acidophilus in a controlled trial where participants reported significant reductions in bloating symptoms [11]. Furthermore, AB-kefir, a probiotic-rich fermented dairy product, showed notable effectiveness in alleviating abdominal bloating over a three-week period [5].
However, not all probiotic treatments yield the same results. A study assessing a probiotic blend for functional constipation found little improvement in bloating, indicating that while some probiotics do help, their efficacy can vary widely depending on the specific strains used and individual circumstances [6]. Additionally, a trial involving multispecies probiotics showed that 68% of IBS participants experienced significant relief from symptoms, including bloating, suggesting multifactorial influences in treatment effectiveness [9]. Overall, while many studies support the use of certain probiotics for managing bloating, individualized approaches remain essential to ensure optimal relief.
Based on user reviews, many individuals have reported significant improvements in symptoms related to bloating and digestive discomfort after using this probiotic. For instance, one user noted that their symptoms, including a bloated abdomen and unpleasant intestinal sensations, vanished after starting the supplement, with additional weight loss as a benefit (Read Review). Others have experienced similar relief, with one reviewer stating that all discomfort disappeared after five days of consistent use (Read Review). Another user emphasized the product's effectiveness in eliminating bloating and normalizing bowel movements, which they appreciated greatly (Read Review).
However, it's crucial to remember that experiences vary widely among users, with some reporting that their symptoms return quickly after discontinuation of the product (Read Review). While many praise the probiotic for balancing gut flora and providing overall digestive support, including improvements in gas formation and stool regularity (Read Review), others may need to consider maintaining consistent use for optimal results.
Users have reported mixed experiences when combining this probiotic with other supplements for managing bloating. Some have noted improvements when taken with specific food combinations, such as cereal or muesli. One reviewer highlighted that they took the probiotic on an empty stomach before breakfast to enhance its effectiveness, leading to significant relief from their bloating and digestive discomfort (Read Review). On the other hand, another user mentioned that initially, they experienced some bloating, which they attributed to the probiotic clashing with their existing gut microflora, indicating that individual responses might vary widely (Read Review).
Additionally, some users have found overall benefits for their gut health and bloating management when taking this supplement consistently. A reviewer stated that once they started using the probiotic, they noticed immediate improvements without any bloating (Read Review). However, others cautioned that symptoms tended to return rapidly after discontinuation, suggesting the importance of sustained use for optimal results (Read Review). Overall, the combination of this probiotic with other dietary components may yield positive outcomes, but users should pay attention to their individual responses to determine the best results.
When it comes to using probiotics for alleviating bloating, multiple studies have identified specific strains that have shown effectiveness. Notably, findings from a comprehensive analysis involving over 9,000 participants suggested that particular strains, such as MTCC 5856 and CNCM I-3856, are the most effective in treating bloating associated with irritable bowel syndrome (IBS) [1]. Other significant evidence points towards Lactobacillus acidophilus and Bifidobacterium lactis as beneficial for reducing bloating symptoms. A double-blind trial revealed that probiotics like Lactobacillus acidophilus NCFM significantly improved bloating symptoms in patients with functional bowel disorders over eight weeks, with noticeable effects seen by the fourth week [11].
For those considering the potential benefits of probiotics, consistency in intake is important. Some studies demonstrated significant improvements in bloating after an 8-week regimen with certain probiotic strains [17]. Moreover, important additional research suggests that combining strains could enhance effectiveness even further. Strategies involving multispecies probiotics have also proven to be advantageous, showing substantial relief in IBS patients after just four weeks [9]. If bloating is your primary concern, focusing on these specific strains, especially within the framework of a consistent probiotic regimen, may provide the relief you're seeking.
10
Immediate results
2 people found this helpful
This product was perfect for me at 55. As soon as I started taking one capsule on an empty stomach, I noticed results after the first day: my bloating disappeared, and my stool returned to normal. I felt relief in my liver and pancreas as well. The quality is high, and the composition is excellent. I highly recommend it for gastrointestinal issues.
7.5
Effective after adjustment
7 people found this helpful
I liked the probiotic and ordered two more cans. Initially, I experienced bloating as the probiotic seemed to be in conflict with the pathogenic microflora, leading to toxin release. However, after five days, the unpleasant sensations and bloating disappeared, and my stool improved. I recommend this probiotic—it’s effective, especially since I have much to compare it with.
9
Temporary relief
4 people found this helpful
Good pills that effectively manage my bloating, and I experience much less constipation! However, once I stop taking them, all problems promptly return the very next day, hence I give it four stars.
9
Bloating alleviated
7 people found this helpful
Liked trying different prebiotics from our pharmacies—no effect. Thanks to these "animals," the bloated abdomen, heaviness inside, and unpleasant intestinal sensations disappeared, and my weight began to decrease. This isn't some form of advertising hype! I read about similar bacteria and took a pill each morning on an empty stomach, followed by breakfast with cereal or muesli.
9
Consistent improvement
2 people found this helpful
A good probiotic that has helped establish regular bowel movements without any bloating. Additionally, the yogurt I created turned out well.
9
Effective treatment
This product truly works by restoring intestinal microflora; my bloating and gas formation have ceased. I highly recommend it.
7
Probiotics show mixed efficacy
Outcome-Specific Efficacy of Different Probiotic Strains and Mixtures in Irritable Bowel Syndrome: A Systematic Review and Network Meta-Analysis.
We explored the effectiveness of various probiotic strains and combinations in treating bloating related to irritable bowel syndrome (IBS). This comprehensive analysis included data from 9,253 participants across 81 studies.
While some probiotics showed promise in alleviating abdominal bloating, the results indicated that only specific strains were effective. Among them, noteworthy probiotics included MTCC 5856 and CNCM I-3856.
Overall, the findings highlight that while probiotics can help some IBS symptoms, not all are effective for bloating, calling for more research to better understand these treatments.
9
Lactobacillus improves bloating symptoms
Probiotic bacteria Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07 versus placebo for the symptoms of bloating in patients with functional bowel disorders: a double-blind study.
We conducted a double-blind, placebo-controlled trial to assess how Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07 affect bloating in patients with functional bowel disorders.
Over eight weeks, patients reported a noticeable improvement in abdominal bloating when taking probiotics compared to those on a placebo.
Notably, results showed significant relief at four weeks and continued improvement by eight weeks, especially among those with irritable bowel syndrome. This suggests probiotics could be beneficial in managing bloating symptoms.
7
Kefir probiotics reduce bloating
Putative Probiotic Strains Isolated from Kefir Improve Gastrointestinal Health Parameters in Adults: a Randomized, Single-Blind, Placebo-Controlled Study.
We explored the effects of probiotic strains from kefir on gastrointestinal health. Fifty-six healthy adults participated in a randomized, single-blind, placebo-controlled study. Over three weeks, those consuming AB-kefir experienced significantly reduced bloating and abdominal pain compared to the control group.
Notably, male participants showed marked improvements, along with shifts in their gut microbiota. This suggests that AB-kefir could be a natural approach to enhance gut health in adults.
4
Probiotic blend shows mixed results
The effect of a probiotic blend on gastrointestinal symptoms in constipated patients: a double blind, randomised, placebo controlled 2-week trial.
In a double-blind, placebo-controlled trial, we examined the effect of a probiotic blend on bloating in adults experiencing functional constipation. Over two weeks, 156 participants were divided to receive either the probiotic or a placebo.
While we found no significant improvements in bloating or other digestive symptoms overall, a noteworthy reduction in flatulence was observed in the probiotic group at specific intervals. This suggests the probiotics may help with some digestive discomfort, though they did not significantly alleviate bloating itself.
8
Probiotics alleviate bloating in IBS
Effect of multispecies probiotics on irritable bowel syndrome: a randomized, double-blind, placebo-controlled trial.
We examined how multispecies probiotics, including Lactobacillus acidophilus, affect bloating in individuals with irritable bowel syndrome (IBS). In a randomized, double-blind trial, 49 IBS patients were split into two groups: one received probiotics and the other a placebo for four weeks.
By the end of the study, we found that 68% of the probiotics group reported significant relief from IBS symptoms, including reduced bloating. Fecal analysis indicated beneficial changes in gut bacteria from the probiotics, highlighting their potential role in improving IBS symptoms.
8
L. rhamnosus may reduce bloating
Effect of Lacticaseibacillus rhamnosus IDCC 3201 on irritable bowel syndrome with constipation: a randomized, double-blind, and placebo-controlled trial.
We focused on how Lacticaseibacillus rhamnosus IDCC 3201 affects bloating in people with irritable bowel syndrome with constipation (IBS-C).
In a randomized, double-blind, placebo-controlled trial involving 30 participants, those taking the probiotic experienced significant improvements.
After 8 weeks, symptoms like abdominal bloating and bowel satisfaction notably improved in the probiotic group compared to those on placebo.
This suggests that RH 3201 may enhance gut health by boosting beneficial bacteria and associated metabolites.
References
Xie P, Luo M, Deng X, Fan J, Xiong L. Outcome-Specific Efficacy of Different Probiotic Strains and Mixtures in Irritable Bowel Syndrome: A Systematic Review and Network Meta-Analysis. Nutrients. 2023;15. doi:10.3390/nu15173856
Wagner NRF, Ramos MRZ, de Oliveira Carlos L, da Cruz MRR, Taconeli CA, et al. Effects of Probiotics Supplementation on Gastrointestinal Symptoms and SIBO after Roux-en-Y Gastric Bypass: a Prospective, Randomized, Double-Blind, Placebo-Controlled Trial. Obes Surg. 2021;31:143. doi:10.1007/s11695-020-04900-x
Maixent JM, Pons O, Sennoune SR, Sadrin S. Clinical effects of Lactobacillus strains as probiotics in the treatment of irritable bowel syndrome. Results from the LAPIBSS trial: Future objectives. Cell Mol Biol (Noisy-le-grand). 2020;66:211.
Sadrin S, Sennoune S, Gout B, Marque S, Moreau J, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis. 2020;52:534. doi:10.1016/j.dld.2019.12.009
Wang MC, Zaydi AI, Lin WH, Lin JS, Liong MT, et al. Putative Probiotic Strains Isolated from Kefir Improve Gastrointestinal Health Parameters in Adults: a Randomized, Single-Blind, Placebo-Controlled Study. Probiotics Antimicrob Proteins. 2020;12:840. doi:10.1007/s12602-019-09615-9
Airaksinen K, Yeung N, Lyra A, Lahtinen SJ, Huttunen T, et al. The effect of a probiotic blend on gastrointestinal symptoms in constipated patients: a double blind, randomised, placebo controlled 2-week trial. Benef Microbes. 2019;10:617. doi:10.3920/BM2018.0163
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Yoon JS, Sohn W, Lee OY, Lee SP, Lee KN, et al. Effect of multispecies probiotics on irritable bowel syndrome: a randomized, double-blind, placebo-controlled trial. J Gastroenterol Hepatol. 2014;29:52. doi:10.1111/jgh.12322
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Ringel-Kulka T, Palsson OS, Maier D, Carroll I, Galanko JA, et al. Probiotic bacteria Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07 versus placebo for the symptoms of bloating in patients with functional bowel disorders: a double-blind study. J Clin Gastroenterol. 2011;45:518. doi:10.1097/MCG.0b013e31820ca4d6
Nova E, Viadel B, Wärnberg J, Carreres JE, Marcos A. Beneficial effects of a synbiotic supplement on self-perceived gastrointestinal well-being and immunoinflammatory status of healthy adults. J Med Food. 2011;14:79. doi:10.1089/jmf.2008.0328
Tsuchiya J, Barreto R, Okura R, Kawakita S, Fesce E, et al. Single-blind follow-up study on the effectiveness of a symbiotic preparation in irritable bowel syndrome. Chin J Dig Dis. 2004;5:169.
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Vorobieva OA, Shih EV, Drozdov VN, Shikh NV. [The results of the use of a combined probiotic ( and spp. ВB-12) in children with gastrointestinal and skin manifestations of food allergy]. Vopr Pitan. 2023;92:79. doi:10.33029/0042-8833-2023-92-3-79-86
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Vitellio P, Celano G, Bonfrate L, Gobbetti M, Portincasa P, et al. Effects of and on Gut Microbiota in Patients with Lactose Intolerance and Persisting Functional Gastrointestinal Symptoms: A Randomised, Double-Blind, Cross-Over Study. Nutrients. 2019;11. doi:10.3390/nu11040886
Hayes SR, Vargas AJ. Probiotics for the Prevention of Pediatric Antibiotic-Associated Diarrhea. Explore (NY). 2016;12:463. doi:10.1016/j.explore.2016.08.015
Goldenberg JZ, Lytvyn L, Steurich J, Parkin P, Mahant S, et al. Probiotics for the prevention of pediatric antibiotic-associated diarrhea. Cochrane Database Syst Rev. 2015. doi:10.1002/14651858.CD004827.pub4
Hauser G, Salkic N, Vukelic K, JajacKnez A, Stimac D. Probiotics for standard triple Helicobacter pylori eradication: a randomized, double-blind, placebo-controlled trial. Medicine (Baltimore). 2015;94:e685. doi:10.1097/MD.0000000000000685
Lan W, Yang H, Zhong Z, Luo C, Huang Q, et al. subsp. LPL-RH improves postoperative gastrointestinal symptoms and nutrition indexes by regulating the gut microbiota in patients with valvular heart disease: a randomized controlled trial. Food Funct. 2024;15:7605. doi:10.1039/d4fo01471e
Şahin K, Şahintürk Y, Köker G, Özçelik Köker G, Bostan F, et al. Metformin with Versus without Concomitant Probiotic Therapy in Newly Diagnosed Patients with Type 2 Diabetes or Prediabetes: A Comparative Analysis in Relation to Glycemic Control, Gastrointestinal Side Effects, and Treatment Compliance. Turk J Gastroenterol. 2022;33:925. doi:10.5152/tjg.2022.211063
Shin CM, Choi YJ, Lee DH, Moon JS, Kim TY, et al. Validity and safety of ID-JPL934 in lower gastrointestinal symptom improvement. Sci Rep. 2021;11:13046. doi:10.1038/s41598-021-92007-3
Zhang C, Jiang J, Tian F, Zhao J, Zhang H, et al. Meta-analysis of randomized controlled trials of the effects of probiotics on functional constipation in adults. Clin Nutr. 2020;39:2960. doi:10.1016/j.clnu.2020.01.005
Marteau P, Le Nevé B, Quinquis L, Pichon C, Whorwell PJ, et al. Consumption of a Fermented Milk Product Containing CNCM I-2494 in Women Complaining of Minor Digestive Symptoms: Rapid Response Which Is Independent of Dietary Fibre Intake or Physical Activity. Nutrients. 2019;11. doi:10.3390/nu11010092
Baştürk A, Artan R, Yılmaz A. Efficacy of synbiotic, probiotic, and prebiotic treatments for irritable bowel syndrome in children: A randomized controlled trial. Turk J Gastroenterol. 2016;27:439. doi:10.5152/tjg.2016.16301
Del Piano M, Carmagnola S, Anderloni A, Andorno S, Ballarè M, et al. The use of probiotics in healthy volunteers with evacuation disorders and hard stools: a double-blind, randomized, placebo-controlled study. J Clin Gastroenterol. 2010;44 Suppl 1:S30. doi:10.1097/MCG.0b013e3181ee31c3
Agrawal A, Houghton LA, Morris J, Reilly B, Guyonnet D, et al. Clinical trial: the effects of a fermented milk product containing Bifidobacterium lactis DN-173 010 on abdominal distension and gastrointestinal transit in irritable bowel syndrome with constipation. Aliment Pharmacol Ther. 2009;29:104. doi:10.1111/j.1365-2036.2008.03853.x
Guyonnet D, Chassany O, Ducrotte P, Picard C, Mouret M, et al. Effect of a fermented milk containing Bifidobacterium animalis DN-173 010 on the health-related quality of life and symptoms in irritable bowel syndrome in adults in primary care: a multicentre, randomized, double-blind, controlled trial. Aliment Pharmacol Ther. 2007;26:475.