5/1/2025
Last update
5/1/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 67 Researches
7.8
USERS' SCORE
Good
Based on 7 Reviews
8.3
Supplement Facts
Serving Size: 1 Vegetable Capsule
Amount Per Serving
%DV
Advanced 40+ Acidophilus 1.5 billion CFUproviding:Lactobacillus. acidophilus, (LA-5®)300 million CFULactobacillus rhamnosus GG (LGG®)300 million CFULactobacillus paracasei (L. CASEI 431®)300 million CFU Bifidobacterium lactis (BB-12®)300 million CFUStreptococcus thermophilus, (TH-4®)300 million CFU
2.4 mg
**
Top Medical Research Studies
9.5
Bifidobacterium lactis reduced diarrhea duration
We explored the impact of Bifidobacterium animalis subsp. lactis BLa80 on diarrhea in young children through a well-structured, randomized, double-blinded, placebo-controlled study.
Our findings show that children receiving the probiotic experienced a significantly shorter duration of diarrhea and a higher recovery rate compared to those given a placebo.
Notably, we also observed beneficial changes in gut microbiome composition and gene functions that promote immune response.
This evidence suggests that Bifidobacterium lactis can effectively support recovery from acute diarrhea in children.
Our findings show that children receiving the probiotic experienced a significantly shorter duration of diarrhea and a higher recovery rate compared to those given a placebo.
Notably, we also observed beneficial changes in gut microbiome composition and gene functions that promote immune response.
This evidence suggests that Bifidobacterium lactis can effectively support recovery from acute diarrhea in children.
Read More
9.5
We explored the effectiveness of a live recombinant Lactococcus lactis vaccine designed to combat enterotoxigenic Escherichia coli, a major cause of diarrhea. The study involved administering the vaccine to mice, who then showed strong immune responses, such as increased antibody production and T cell activation.
After being challenged with ETEC, these mice exhibited complete protection from the disease. This suggests that the Lactococcus lactis vaccine could be a promising oral vaccine candidate against E. coli-related diarrhea.
After being challenged with ETEC, these mice exhibited complete protection from the disease. This suggests that the Lactococcus lactis vaccine could be a promising oral vaccine candidate against E. coli-related diarrhea.
Read More
9
We evaluated the effectiveness of Bifidobacterium lactis XLTG11 in treating acute watery diarrhea in children through a rigorous randomized, double-blind, placebo-controlled trial.
Children who received the probiotic alongside their conventional treatment had significantly shorter diarrhea durations and hospital stays compared to those who only got standard care. Additionally, those taking Bifidobacterium showed better improvement rates and healthier gut microbiomes after treatment.
Overall, this study suggests that Bifidobacterium lactis can be a beneficial adjunct therapy for children suffering from diarrhea.
Children who received the probiotic alongside their conventional treatment had significantly shorter diarrhea durations and hospital stays compared to those who only got standard care. Additionally, those taking Bifidobacterium showed better improvement rates and healthier gut microbiomes after treatment.
Overall, this study suggests that Bifidobacterium lactis can be a beneficial adjunct therapy for children suffering from diarrhea.
Read More
Most Useful Reviews
9
No adverse effects
11 people found this helpful
Very pleased. This is a wonderful product as I have lactose intolerance. I can enjoy a large soft serve "sweet frog" frozen yogurt without experiencing diarrhoea or stomach upset. No adverse side effects to report as of this review.
Read More
10
Stops diarrhoea
Happy gut! I appreciate the quality of the ingredients in this supplement; the packaging is excellent. It comes in just the right size for the effect I desire. One drop daily has worked wonders for my intestines. Since I began using it, my diarrhoea has ceased. I will continue purchasing this. After several months of use, I feel fantastic and highly recommend it to anyone aiming for good health.
Read More
10
Relieved stomach
My stomach feels relieved, and the diarrhoea has subsided.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 67 Researches
7.8
- All Researches
9.5
We explored the impact of Lactobacillus acidophilus and L. plantarum on patients suffering from diarrhea-predominant irritable bowel syndrome (IBS-D). In a randomized, single-blinded clinical trial of 100 patients, some received standard IBS treatment alone while others added probiotics to their therapy.
After 12 weeks, both groups saw improvements, but those who took probiotics reported significantly better outcomes. Patients using probiotics experienced greater reductions in IBS symptoms, achieving near complete relief, while some on standard treatment still faced moderate symptoms. This suggests probiotics could enhance IBS management.
After 12 weeks, both groups saw improvements, but those who took probiotics reported significantly better outcomes. Patients using probiotics experienced greater reductions in IBS symptoms, achieving near complete relief, while some on standard treatment still faced moderate symptoms. This suggests probiotics could enhance IBS management.
Read More
9.5
We explored the impact of Lactobacillus acidophilus and L. plantarum on patients suffering from diarrhea-predominant irritable bowel syndrome (IBS-D). In a randomized, single-blinded clinical trial of 100 patients, some received standard IBS treatment alone while others added probiotics to their therapy.
After 12 weeks, both groups saw improvements, but those who took probiotics reported significantly better outcomes. Patients using probiotics experienced greater reductions in IBS symptoms, achieving near complete relief, while some on standard treatment still faced moderate symptoms. This suggests probiotics could enhance IBS management.
After 12 weeks, both groups saw improvements, but those who took probiotics reported significantly better outcomes. Patients using probiotics experienced greater reductions in IBS symptoms, achieving near complete relief, while some on standard treatment still faced moderate symptoms. This suggests probiotics could enhance IBS management.
Read More
9.5
Lactobacillus shows promise for diarrhea
We aimed to explore how Lactobacillus acidophilus can help relieve diarrhea symptoms associated with irritable bowel syndrome (IBS) and antibiotic-associated diarrhea (AAD).
In a study with 54 patients, those taking the probiotic Neobiotic Lactobalance® for 21 days saw significant reductions in diarrhea severity and abdominal pain, with scores dropping impressively on the Gastrointestinal Symptom Rating Scale.
Fecal analysis indicated improved intestinal health, highlighting Lactobacillus's potential benefits for those struggling with these conditions.
In a study with 54 patients, those taking the probiotic Neobiotic Lactobalance® for 21 days saw significant reductions in diarrhea severity and abdominal pain, with scores dropping impressively on the Gastrointestinal Symptom Rating Scale.
Fecal analysis indicated improved intestinal health, highlighting Lactobacillus's potential benefits for those struggling with these conditions.
Read More
9.5
Bifidobacterium lactis reduced diarrhea duration
We explored the impact of Bifidobacterium animalis subsp. lactis BLa80 on diarrhea in young children through a well-structured, randomized, double-blinded, placebo-controlled study.
Our findings show that children receiving the probiotic experienced a significantly shorter duration of diarrhea and a higher recovery rate compared to those given a placebo.
Notably, we also observed beneficial changes in gut microbiome composition and gene functions that promote immune response.
This evidence suggests that Bifidobacterium lactis can effectively support recovery from acute diarrhea in children.
Our findings show that children receiving the probiotic experienced a significantly shorter duration of diarrhea and a higher recovery rate compared to those given a placebo.
Notably, we also observed beneficial changes in gut microbiome composition and gene functions that promote immune response.
This evidence suggests that Bifidobacterium lactis can effectively support recovery from acute diarrhea in children.
Read More
9.5
We explored the effectiveness of a live recombinant Lactococcus lactis vaccine designed to combat enterotoxigenic Escherichia coli, a major cause of diarrhea. The study involved administering the vaccine to mice, who then showed strong immune responses, such as increased antibody production and T cell activation.
After being challenged with ETEC, these mice exhibited complete protection from the disease. This suggests that the Lactococcus lactis vaccine could be a promising oral vaccine candidate against E. coli-related diarrhea.
After being challenged with ETEC, these mice exhibited complete protection from the disease. This suggests that the Lactococcus lactis vaccine could be a promising oral vaccine candidate against E. coli-related diarrhea.
Read More
User Reviews
USERS' SCORE
Good
Based on 7 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
No adverse effects
11 people found this helpful
Very pleased. This is a wonderful product as I have lactose intolerance. I can enjoy a large soft serve "sweet frog" frozen yogurt without experiencing diarrhoea or stomach upset. No adverse side effects to report as of this review.
Read More
10
Stops diarrhoea
Happy gut! I appreciate the quality of the ingredients in this supplement; the packaging is excellent. It comes in just the right size for the effect I desire. One drop daily has worked wonders for my intestines. Since I began using it, my diarrhoea has ceased. I will continue purchasing this. After several months of use, I feel fantastic and highly recommend it to anyone aiming for good health.
Read More
10
Relieved stomach
My stomach feels relieved, and the diarrhoea has subsided.
Read More
9
Improved gastric health
A must-have product for me. As a long-time sufferer of Candida, this has become one of my essentials. I first bought it 4-5 years ago, noticing a significant improvement in my gastric health, bloating, diarrhoea, and overall health. I rely on it after consuming too many carbs or experiencing stomach discomfort, and it's a travel companion for me. I've tried various products, but this one truly makes a difference. Thank you!
Read More
9
Restores intestinal activity
Known in Italy as BIOFLOR, this prebiotic, along with multidiphilus, plays a crucial role in restoring intestinal activity. It is especially useful for traveller's diarrhoea and effectively recolonises the intestines.
Read More
Frequently Asked Questions
10
Relieved stomach
My stomach feels relieved, and the diarrhoea has subsided.
9
Improved gastric health
A must-have product for me. As a long-time sufferer of Candida, this has become one of my essentials. I first bought it 4-5 years ago, noticing a significant improvement in my gastric health, bloating, diarrhoea, and overall health. I rely on it after consuming too many carbs or experiencing stomach discomfort, and it's a travel companion for me. I've tried various products, but this one truly makes a difference. Thank you!
10
Stops diarrhoea
Happy gut! I appreciate the quality of the ingredients in this supplement; the packaging is excellent. It comes in just the right size for the effect I desire. One drop daily has worked wonders for my intestines. Since I began using it, my diarrhoea has ceased. I will continue purchasing this. After several months of use, I feel fantastic and highly recommend it to anyone aiming for good health.
7.5
Relaxes intestines
A very good product for after experiencing diarrhoea or after eating something that doesn't agree with you. It helps your intestines to relax and function properly once again.
9
Restores intestinal activity
Known in Italy as BIOFLOR, this prebiotic, along with multidiphilus, plays a crucial role in restoring intestinal activity. It is especially useful for traveller's diarrhoea and effectively recolonises the intestines.
9
Lactobacillus acidophilus aids diarrhea recovery
We explored the impact of Lactobacillus acidophilus paired with montmorillonite powder on children suffering from rotavirus enteritis. In a study involving 94 kids, we divided them into two groups. One received standard care, while the other got the probiotic treatment as well. After five days, we found that children receiving the compound had faster relief from diarrhea, vomiting, fever, and dehydration. While there was an improvement in inflammatory responses, the difference in C-reactive protein levels wasn’t significant, and both groups reported a similar rate of side effects.
8
We looked into how effective probiotics, specifically Lactobacillus acidophilus and others commonly available in Japan, are in treating diarrhea caused by acute gastroenteritis in children.
In our analysis of 14 studies, we found that children who took probiotics had diarrhea lasting about one day shorter and fewer were hospitalized compared to those receiving a placebo.
However, the overall evidence is considered very low, suggesting that while there might be some benefits, more research is needed.
In our analysis of 14 studies, we found that children who took probiotics had diarrhea lasting about one day shorter and fewer were hospitalized compared to those receiving a placebo.
However, the overall evidence is considered very low, suggesting that while there might be some benefits, more research is needed.
7
We examined how Bifidobacterium lactis BB-12 and yogurt can help counter the effects of the antibiotic amoxicillin-clavulanate (AMC) on mouse gut health. Over ten days, male and female mice were treated with BB-12, yogurt, or a combination, while others received saline with AMC.
Interestingly, male mice on AMC lost weight, but those taking BB-12 or yogurt showed body weights similar to healthy controls after a week. Both BB-12 and yogurt appeared to balance gut bacteria, potentially lessening dysbiosis caused by antibiotics.
Interestingly, male mice on AMC lost weight, but those taking BB-12 or yogurt showed body weights similar to healthy controls after a week. Both BB-12 and yogurt appeared to balance gut bacteria, potentially lessening dysbiosis caused by antibiotics.
5
We examined the effects of a combination of probiotics and zinc on young children suffering from acute gastroenteritis. In this randomized controlled trial, children were split into two groups: one received probiotics with zinc, while the other received probiotics alone.
While we found that the combination treatment didn’t significantly reduce the severity of diarrhea, it did help children recover faster compared to those who only took probiotics. This subtle yet positive impact suggests that probiotics paired with zinc could be beneficial in managing diarrhea symptoms.
While we found that the combination treatment didn’t significantly reduce the severity of diarrhea, it did help children recover faster compared to those who only took probiotics. This subtle yet positive impact suggests that probiotics paired with zinc could be beneficial in managing diarrhea symptoms.
References
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- Wei Q, Song LY, Rao R, Yang HW, Wen YP, et al. The Impact of Combined Therapy with Lactobacillus acidophilus and Montmorillonite Powder on the Inflammatory Response in Pediatric Rotavirus Enteritis. Int Arch Allergy Immunol. 2024. 10.1159/000542593
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- Alharbi BF, Alateek AA. Investigating the influence of probiotics in preventing Traveler's diarrhea: Meta-analysis based systematic review. Travel Med Infect Dis. 2024;59:102703. 10.1016/j.tmaid.2024.102703
- Miranda-Yuquilema J, Taboada J, Once V, Coyago M, Briñez W. Effect of Agroindustrial Waste Substrate Fermented with Lactic Acid Bacteria and Yeast on Changes in the Gut Microbiota of Guinea Pigs. Microorganisms. 2024;12. 10.3390/microorganisms12010133
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- Kumar M, Kala A, Chaudhary LC, Agarwal N, Kochewad SA. Microencapsulated and Lyophilized Lactobacillus acidophilus Improved Gut Health and Immune Status of Preruminant Calves. Probiotics Antimicrob Proteins. 2022;14:523. 10.1007/s12602-021-09821-4
- Chorawala MR, Chauhan S, Patel R, Shah G. Cell Wall Contents of Probiotics (Lactobacillus species) Protect Against Lipopolysaccharide (LPS)-Induced Murine Colitis by Limiting Immuno-inflammation and Oxidative Stress. Probiotics Antimicrob Proteins. 2021;13:1005. 10.1007/s12602-020-09738-4
- Gunaratnam S, Diarra C, Paquette PD, Ship N, Millette M, et al. The Acid-Dependent and Independent Effects of Lactobacillus acidophilus CL1285, Lacticaseibacillus casei LBC80R, and Lacticaseibacillus rhamnosus CLR2 on Clostridioides difficile R20291. Probiotics Antimicrob Proteins. 2021;13:949. 10.1007/s12602-020-09729-5
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- Gwee KA, Lee WRW, Chua Q, Chiou FK, Aw MM, et al. The evidence for probiotics in the treatment of digestive disorders in the pediatric population. J Gastroenterol Hepatol. 2025;40:41. 10.1111/jgh.16809
- Shah J, Adnan SH, Yousaf MS, Din SJU, Haq MU, et al. A Multi-Hospital Comparative Study on the Efficacy of Probiotics Versus Placebo in Preventing Antibiotic-Associated Diarrhea in Adult Patients. Cureus. 2024;16:e70881. 10.7759/cureus.70881
- Shawky LM, Abo El Wafa SM, Behery M, Bahr MH, Abu Alnasr MT, et al. Lactobacillus rhamnosus GG and Tannic Acid Synergistically Promote the Gut Barrier Integrity in a Rat Model of Experimental Diarrhea via Selective Immunomodulatory Cytokine Targeting. Mol Nutr Food Res. 2024;68:e2400295. 10.1002/mnfr.202400295
- Anvarifard P, Anbari M, Ghalichi F, Ghoreishi Z, Zarezadeh M. The effectiveness of probiotics as an adjunct therapy in patients under mechanical ventilation: an umbrella systematic review and meta-analysis. Food Funct. 2024;15:5737. 10.1039/d3fo04653b
- Abdulah DM, Sulaiman SJ, Ahmed ZW. Effect of probiotics plus zinc supplementation on clinical outcomes of infants and children with acute infectious diarrhea: a randomized controlled trial. Clin Exp Pediatr. 2024;67:203. 10.3345/cep.2023.01340
- Waitzberg D, Guarner F, Hojsak I, Ianiro G, Polk DB, et al. Can the Evidence-Based Use of Probiotics (Notably Saccharomyces boulardii CNCM I-745 and Lactobacillus rhamnosus GG) Mitigate the Clinical Effects of Antibiotic-Associated Dysbiosis?. Adv Ther. 2024;41:901. 10.1007/s12325-024-02783-3
- Saviano A, Petruzziello C, Cancro C, Macerola N, Petti A, et al. The Efficacy of a Mix of Probiotics ( LMG P-27481 and GG ATCC 53103) in Preventing Antibiotic-Associated Diarrhea and Infection in Hospitalized Patients: Single-Center, Open-Label, Randomized Trial. Microorganisms. 2024;12. 10.3390/microorganisms12010198
- Poeta M, Cioffi V, Tarallo A, Damiano C, Lo Vecchio A, et al. Postbiotic Preparation of against Diarrhea and Oxidative Stress Induced by Spike Protein of SARS-CoV-2 in Human Enterocytes. Antioxidants (Basel). 2023;12. 10.3390/antiox12101878
- Mego M, Danis R, Chovanec J, Jurisova S, Bystricky B, et al. Randomized double-blind, placebo-controlled multicenter phase III study of prevention of irinotecan-induced diarrhea by a probiotic mixture containing Bifidobacterium BB-12 LGG in colorectal cancer patients. Front Oncol. 2023;13:1168654. 10.3389/fonc.2023.1168654
- Yang Q, Hu Z, Lei Y, Li X, Xu C, et al. Overview of systematic reviews of probiotics in the prevention and treatment of antibiotic-associated diarrhea in children. Front Pharmacol. 2023;14:1153070. 10.3389/fphar.2023.1153070
- Niu H, Zhou X, Liu P, Wu Y, Lyu L, et al. Lactobacillus rhamnosus MN-431 Metabolic Tryptophan Alleviates Complementary Food-Induced Diarrhea through PXR-NF-κB Pathway and AHR-Th17 Cell Response Pathways. Mol Nutr Food Res. 2023;67:e2200530. 10.1002/mnfr.202200530
- Li J, Li Q, Wu Q, Gao N, Wang Z, et al. Exopolysaccharides of Lactobacillus rhamnosus GG ameliorate Salmonella typhimurium-induced intestinal inflammation via the TLR4/NF-κB/MAPK pathway. J Anim Sci Biotechnol. 2023;14:23. 10.1186/s40104-023-00830-7
- Uttarwar RG, Mekonnen SA, Van Beeck W, Wang A, Finnegan P, et al. Effects of Bifidobacterium animalis subsp. lactis BB-12 and yogurt on mice during oral antibiotic administration. Microbiol Res. 2024;286:127794. 10.1016/j.micres.2024.127794
- Chen K, Jin S, Ma Y, Cai L, Xu P, et al. Adjudicative efficacy of Bifidobacterium animalis subsp. lactis BLa80 in treating acute diarrhea in children: a randomized, double-blinded, placebo-controlled study. Eur J Clin Nutr. 2024;78:501. 10.1038/s41430-024-01428-6
- Chen K, Jin S, Ma Y, Cai L, Xu P, et al. Adjunctive efficacy of Lactis XLTG11 for Acute diarrhea in children: A randomized, blinded, placebo-controlled study. Nutrition. 2023;111:112052. 10.1016/j.nut.2023.112052
- Pang J, Liu Y, Kang L, Ye H, Zang J, et al. Bifidobacterium animalis Promotes the Growth of Weaning Piglets by Improving Intestinal Development, Enhancing Antioxidant Capacity, and Modulating Gut Microbiota. Appl Environ Microbiol. 2022;88:e0129622. 10.1128/aem.01296-22
- Şahin K, Şahintürk Y, Köker G, Özçelik Köker G, Bostan F, et al. Metformin with Versus without Concomitant Probiotic Therapy in Newly Diagnosed Patients with Type 2 Diabetes or Prediabetes: A Comparative Analysis in Relation to Glycemic Control, Gastrointestinal Side Effects, and Treatment Compliance. Turk J Gastroenterol. 2022;33:925. 10.5152/tjg.2022.211063
- Xu B, Liang S, Zhao J, Li X, Guo J, et al. subsp. XLTG11 improves antibiotic-related diarrhea by alleviating inflammation, enhancing intestinal barrier function and regulating intestinal flora. Food Funct. 2022;13:6404. 10.1039/d1fo04305f
- Liu B, Wang C, Huasai S, Han A, Zhang J, et al. Compound Probiotics Improve the Diarrhea Rate and Intestinal Microbiota of Newborn Calves. Animals (Basel). 2022;12. 10.3390/ani12030322
- Michels M, Córneo E, Cucker L, Simon CS, de Jesus GFA, et al. Bifidobacterium lactis CCT 7858 Improves Gastrointestinal Symptoms by Antibiotics Treatment: a Double-Blind, Randomized, Placebo-Controlled Trial. Probiotics Antimicrob Proteins. 2023;15:738. 10.1007/s12602-021-09900-6
- Cheng J, Laitila A, Ouwehand AC. subsp. HN019 Effects on Gut Health: A Review. Front Nutr. 2021;8:790561. 10.3389/fnut.2021.790561
- Li Z, Zhu G, Li C, Lai H, Liu X, et al. Which Probiotic Is the Most Effective for Treating Acute Diarrhea in Children? A Bayesian Network Meta-Analysis of Randomized Controlled Trials. Nutrients. 2021;13. 10.3390/nu13124319
- Guo Y, Li Z, Deng M, Li Y, Liu G, et al. Effects of a multi-strain probiotic on growth, health, and fecal bacterial flora of neonatal dairy calves. Anim Biosci. 2022;35:204. 10.5713/ab.21.0084
- Merenstein D, Fraser CM, Roberts RF, Liu T, Grant-Beurmann S, et al. subsp. BB-12 Protects against Antibiotic-Induced Functional and Compositional Changes in Human Fecal Microbiome. Nutrients. 2021;13. 10.3390/nu13082814
- Kluijfhout S, Trieu TV, Vandenplas Y. Efficacy of the Probiotic Probiotical Confirmed in Acute Gastroenteritis. Pediatr Gastroenterol Hepatol Nutr. 2020;23:464. 10.5223/pghn.2020.23.5.464
- Shin SY, Park S, Moon JM, Kim K, Kim JW, et al. Compositional Changes in the Gut Microbiota of Responders and Non-responders to Probiotic Treatment Among Patients With Diarrhea-predominant Irritable Bowel Syndrome: A Post Hoc Analysis of a Randomized Clinical Trial. J Neurogastroenterol Motil. 2022;28:642. 10.5056/jnm21202
- Shen SR, Chen WJ, Chu HF, Wu SH, Wang YR, et al. Amelioration of 5-fluorouracil-induced intestinal mucositis by Streptococcus thermophilus ST4 in a mouse model. PLoS One. 2021;16:e0253540. 10.1371/journal.pone.0253540
- Skrzydło-Radomańska B, Prozorow-Król B, Cichoż-Lach H, Majsiak E, Bierła JB, et al. The Effectiveness and Safety of Multi-Strain Probiotic Preparation in Patients with Diarrhea-Predominant Irritable Bowel Syndrome: A Randomized Controlled Study. Nutrients. 2021;13. 10.3390/nu13030756
- Velasco M, Requena T, Delgado-Iribarren A, Peláez C, Guijarro C. Probiotic Yogurt for the Prevention of Antibiotic-associated Diarrhea in Adults: A Randomized Double-blind Placebo-controlled Trial. J Clin Gastroenterol. 2019;53:717. 10.1097/MCG.0000000000001131
- Levit R, Savoy de Giori G, de Moreno de LeBlanc A, LeBlanc JG. Folate-producing lactic acid bacteria reduce inflammation in mice with induced intestinal mucositis. J Appl Microbiol. 2018;125:1494. 10.1111/jam.14038
- Zhou H, Li S, Chen Y, Zhang Q, Bai X, et al. Evaluation of Streptococcus thermophilus IFFI 6038 Microcapsules Prepared Using an Ultra-fine Particle Processing System. AAPS PharmSciTech. 2018;19:1020. 10.1208/s12249-017-0907-x
- Feng JR, Wang F, Qiu X, McFarland LV, Chen PF, et al. Efficacy and safety of probiotic-supplemented triple therapy for eradication of Helicobacter pylori in children: a systematic review and network meta-analysis. Eur J Clin Pharmacol. 2017;73:1199. 10.1007/s00228-017-2291-6
- Yoon H, Park YS, Lee DH, Seo JG, Shin CM, et al. Effect of administering a multi-species probiotic mixture on the changes in fecal microbiota and symptoms of irritable bowel syndrome: a randomized, double-blind, placebo-controlled trial. J Clin Biochem Nutr. 2015;57:129. 10.3164/jcbn.15-14
- Ringel-Kulka T, Kotch JB, Jensen ET, Savage E, Weber DJ. Randomized, double-blind, placebo-controlled study of synbiotic yogurt effect on the health of children. J Pediatr. 2015;166:1475. 10.1016/j.jpeds.2015.02.038
- Ivakhnenko ES, Nian'kovskiĭ SL. [Effect of probiotics on the dynamics of gastrointestinal symptoms of food allergy to cow's milk protein in infants]. Georgian Med News. 2013.
- Kolling GL, Wu M, Warren CA, Durmaz E, Klaenhammer TR, et al. Lactic acid production by Streptococcus thermophilus alters Clostridium difficile infection and in vitro Toxin A production. Gut Microbes. 2012;3:523. 10.4161/gmic.21757
- Ki Cha B, Mun Jung S, Hwan Choi C, Song ID, Woong Lee H, et al. The effect of a multispecies probiotic mixture on the symptoms and fecal microbiota in diarrhea-dominant irritable bowel syndrome: a randomized, double-blind, placebo-controlled trial. J Clin Gastroenterol. 2012;46:220. 10.1097/MCG.0b013e31823712b1
- Cai X, Yi P, Chen X, Wu J, Lan G, et al. Intake of compound probiotics accelerates the construction of immune function and gut microbiome in Holstein calves. Microbiol Spectr. 2024;12:e0190923. 10.1128/spectrum.01909-23
- Yu J, Fu J, Liu H, Kang C, Wang Z, et al. Application of Recombinant Lactic Acid Bacteria (LAB) Live Vector Oral Vaccine in the Prevention of F4+ Enterotoxigenic . Vaccines (Basel). 2024;12. 10.3390/vaccines12030304
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